BR112014024033A8 - Formulação vesicular, método para o tratamento da rosácea e uso de um ou mais fosfo, sulfolipídios e surfactantes - Google Patents
Formulação vesicular, método para o tratamento da rosácea e uso de um ou mais fosfo, sulfolipídios e surfactantesInfo
- Publication number
- BR112014024033A8 BR112014024033A8 BR112014024033A BR112014024033A BR112014024033A8 BR 112014024033 A8 BR112014024033 A8 BR 112014024033A8 BR 112014024033 A BR112014024033 A BR 112014024033A BR 112014024033 A BR112014024033 A BR 112014024033A BR 112014024033 A8 BR112014024033 A8 BR 112014024033A8
- Authority
- BR
- Brazil
- Prior art keywords
- rosacea
- treatment
- sulpholipids
- phospho
- surfactants
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/688—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols both hydroxy compounds having nitrogen atoms, e.g. sphingomyelins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/77—Polymers containing oxygen of oxiranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
Abstract
FORMULAÇÃO VESICULAR E SEU USO. A presente invenção refere-se a formulações vesiculares para o tratamento da rosácea. Refere-se também a um método de tratamento de rosácea, compreendendo a administração de uma formulação vesicular acordo com a invenção.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1205642.0A GB201205642D0 (en) | 2012-03-29 | 2012-03-29 | Vesicular formulations |
PCT/EP2013/056694 WO2013144289A1 (en) | 2012-03-29 | 2013-03-28 | Vesicular formulations |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112014024033A2 BR112014024033A2 (pt) | 2017-06-20 |
BR112014024033A8 true BR112014024033A8 (pt) | 2017-07-25 |
Family
ID=46159988
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014024033A BR112014024033A8 (pt) | 2012-03-29 | 2013-03-28 | Formulação vesicular, método para o tratamento da rosácea e uso de um ou mais fosfo, sulfolipídios e surfactantes |
Country Status (19)
Country | Link |
---|---|
US (1) | US9555051B2 (pt) |
EP (1) | EP2830630A1 (pt) |
JP (1) | JP2015511618A (pt) |
KR (1) | KR20150004798A (pt) |
CN (1) | CN104349782A (pt) |
AU (1) | AU2013241701A1 (pt) |
BR (1) | BR112014024033A8 (pt) |
CA (1) | CA2867749A1 (pt) |
CL (1) | CL2014002547A1 (pt) |
CO (1) | CO7121334A2 (pt) |
EA (1) | EA038899B1 (pt) |
GB (2) | GB201205642D0 (pt) |
IL (1) | IL234747A0 (pt) |
IN (1) | IN2014DN07913A (pt) |
MX (1) | MX2014011516A (pt) |
NZ (1) | NZ700472A (pt) |
PH (1) | PH12014502065A1 (pt) |
SG (1) | SG11201406144TA (pt) |
WO (1) | WO2013144289A1 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102770162B (zh) | 2009-08-21 | 2016-09-28 | 靶向递送技术有限公司 | 囊泡制剂 |
JP6822962B2 (ja) * | 2014-12-23 | 2021-01-27 | カムルス エービー | 制御放出製剤 |
ES2895910T3 (es) | 2015-06-30 | 2022-02-23 | Sequessome Tech Holdings Limited | Composiciones multifásicas |
US20190083386A1 (en) | 2017-09-15 | 2019-03-21 | Ampersand Biopharmaceuticals, Inc. | Methods and formulations for transdermal administration of buffering agents |
WO2022180199A1 (en) * | 2021-02-25 | 2022-09-01 | Exinov | Emulsion for use in the treatment of rosacea |
Family Cites Families (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60136511A (ja) | 1983-12-26 | 1985-07-20 | Eisai Co Ltd | 高尿酸血症治療剤 |
JPS63501289A (ja) | 1985-09-27 | 1988-05-19 | ザ リ−ジエンツ オブ ザ ユニバ−シテイ オブ カリフオルニア | リポソ−ム経皮薬剤供給系 |
JPS6295134A (ja) | 1985-10-21 | 1987-05-01 | Nippon Saafuakutanto Kogyo Kk | リポソ−ムの製造法 |
US5015483A (en) | 1989-02-09 | 1991-05-14 | Nabisco Brands, Inc. | Liposome composition for the stabilization of oxidizable substances |
US5498607A (en) | 1990-07-30 | 1996-03-12 | University Of Miami | Treatment for hypercholesterolemia |
CA2067754C (en) | 1990-08-24 | 2002-06-04 | Gregor Cevc | Preparation for the application of agents in mini-droplets |
US6165500A (en) | 1990-08-24 | 2000-12-26 | Idea Ag | Preparation for the application of agents in mini-droplets |
US5498420A (en) | 1991-04-12 | 1996-03-12 | Merz & Co. Gmbh & Co. | Stable small particle liposome preparations, their production and use in topical cosmetic, and pharmaceutical compositions |
AU4327193A (en) | 1992-07-08 | 1994-01-31 | Dianorm-Gerate G. Maierhofer | Liposomes, method of preparing them and their use in the preparation of drugs |
FR2714382B1 (fr) | 1993-12-27 | 1996-02-02 | Roussel Uclaf | Phospholipides vecteur de molécule active, leur préparation et leur utilisation dans des compositions cosmétiques ou dermatologiques. |
DE4447287C1 (de) | 1994-12-30 | 1996-11-07 | Cevc Gregor | Präparat zum Wirkstofftransport durch Barrieren |
US5902604A (en) | 1995-06-06 | 1999-05-11 | Board Of Regents, The University Of Texas System | Submicron liposome suspensions obtained from preliposome lyophilizates |
FR2767691B1 (fr) | 1997-08-27 | 2000-02-18 | Oreal | Utilisation d'une dispersion a base de vehicules lipidiques comme composition anti-inflammatoire |
PL202454B1 (pl) * | 1997-11-19 | 2009-06-30 | Intendis Gmbh | Kompozycja farmaceutyczna zawierająca kwas azelainowy i jej zastosowanie |
US6165997A (en) | 1997-11-20 | 2000-12-26 | Statens Serum Institut | Phospholipids having antimicrobial activity with or without the presence of antimicrobials |
KR20010106462A (ko) | 1998-09-01 | 2001-11-29 | 체에베체 그레고르 | 배리어를 가로지른 대전 침투제의 전기적으로 제어된수송 |
TR200101790T2 (tr) | 1998-12-23 | 2001-10-22 | Idea Ag. | Yayılgan olmayan in vivo topik uygulamalar için geliştirilmiş formül |
SI1031346T1 (en) | 1999-01-27 | 2002-08-31 | Idea Ag | Noninvasive vaccination through the skin |
US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
WO2001001962A1 (en) | 1999-07-05 | 2001-01-11 | Idea Ag. | A method for the improvement of transport across adaptable semi-permeable barriers |
US6248728B1 (en) | 2000-03-10 | 2001-06-19 | Kansas State University Research Foundation | Phosphatidylcholine compositions and methods for lowering intestinal absorption and plasma levels of cholesterol |
US6191121B1 (en) * | 2000-04-06 | 2001-02-20 | Nicholas V. Perricone | Treatment of skin damage using polyenylphosphatidylcholine |
ES2295149T3 (es) | 2000-04-12 | 2008-04-16 | Liplasome Pharma A/S | Sistemas de suministro de farmacos contra infecciones parasiticas. |
TWI281407B (en) | 2000-09-18 | 2007-05-21 | Vasogen Ireland Ltd | Apoptosis-mimicking synthetic entities and use thereof in medical treatment |
US20030064948A1 (en) | 2001-02-08 | 2003-04-03 | Alfred Fahr | Invasomes for therapy of disorders, their preparation and use |
CZ20033241A3 (cs) | 2001-05-31 | 2004-08-18 | Pharmaciaácorporation | Kůži prostupující přípravek obsahující selektivně inhibující cyklooxygenázu@@ a jednosytný alkohol |
JP2004535434A (ja) | 2001-06-25 | 2004-11-25 | デピユイ | 関節炎にかかった関節の処置のためのグリコサミノグリカン類のリポソームカプセル化 |
CA2368656A1 (en) | 2002-01-21 | 2003-07-21 | Vasogen Ireland Limited | Receptor-ligand pairing for anti-inflammatory response |
EP1534213B1 (en) | 2002-03-13 | 2013-04-24 | Sköld, Thomas | Water-based delivery systems |
US20040009180A1 (en) | 2002-07-11 | 2004-01-15 | Allergan, Inc. | Transdermal botulinum toxin compositions |
JP2004131432A (ja) | 2002-10-11 | 2004-04-30 | Kumamoto Technology & Industry Foundation | 悪性腫瘍抑制剤 |
KR20050055723A (ko) | 2002-10-11 | 2005-06-13 | 이데아 아게 | 생체 내, 특히 피부를 통한 비침투성 약물 적용 및 반투성배리어를 통한 향상된 전달을 위한, 적어도 세 가지 양친성성분을 포함하는, 증가된 변형성을 갖는 응집체 |
US7473432B2 (en) | 2002-10-11 | 2009-01-06 | Idea Ag | NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery |
JP2006525368A (ja) | 2003-05-02 | 2006-11-09 | アロネックス,ファーマシューティカルズ,インコーポレーテッド | 脂質白金錯体およびその使用方法 |
EA200600297A1 (ru) | 2003-07-21 | 2006-08-25 | Васоджен Айеленд Лимитед | Лечение острого воспалительного состояния |
JP2005179313A (ja) * | 2003-12-24 | 2005-07-07 | Shu Uemura:Kk | 皮膚化粧料用基剤の製造方法および皮膚化粧料 |
US7476432B2 (en) | 2004-05-28 | 2009-01-13 | Tecton Products | Phosphorescent pultrusion |
WO2006050926A2 (en) | 2004-11-12 | 2006-05-18 | Idea Ag | Extended surface aggregates in the treatment of skin conditions |
WO2006086992A2 (en) | 2005-02-18 | 2006-08-24 | Liplasome Pharma A/S | Drug delivery systems containing phqspholipase a2 degradable lipid prodrug derivatives and the therapeutic uses thereof as. e.g. wound healing agents and peroxisome proliferator activated receptor ligands |
US20070042008A1 (en) | 2005-08-18 | 2007-02-22 | Bodybio, Inc. | Compositions containing phosphatidylcholine and essential fatty acids |
JP5432525B2 (ja) | 2005-08-29 | 2014-03-05 | セプシキュア、リミテッド、ライアビリティ、カンパニー | グラム陽性菌によって引き起こされる状態の治療又は予防方法 |
JP2009520824A (ja) | 2005-12-20 | 2009-05-28 | セネストラ エルエルシー | オメガ3脂肪酸製剤 |
JP5009547B2 (ja) * | 2006-03-31 | 2012-08-22 | 株式会社コーセー | 顔料とリポソームを含む化粧料 |
US7544375B1 (en) | 2006-06-12 | 2009-06-09 | Swiss Skin Repair, Inc. | Composition |
ES2599630T3 (es) | 2006-09-28 | 2017-02-02 | Hadasit Medical Research Services & Development Limited | Uso de glicerofosfolípidos para lubricación de las articulaciones |
JP4732307B2 (ja) | 2006-11-20 | 2011-07-27 | 株式会社アンズコーポレーション | ナノエマルション及びそれを配合した化粧料 |
US20100130611A1 (en) | 2006-12-20 | 2010-05-27 | Cenestra Llc | Omega 3 fatty acid formulations |
EP1938801A1 (en) | 2006-12-22 | 2008-07-02 | Biofrontera Bioscience GmbH | Nanoemulsion |
US9511016B2 (en) | 2007-06-12 | 2016-12-06 | Epicentrx, Inc. | Topical composition for treating pain |
ITVR20080006A1 (it) | 2008-01-23 | 2009-07-24 | David Ceretta | Apparato per la realizzazione di elementi d'impasto |
ES2335636B1 (es) | 2008-02-29 | 2011-05-11 | Lipotec, S.A. | Composicion cosmetica o dermofarmaceutica de micelas mixtas. |
JP2009256331A (ja) | 2008-03-25 | 2009-11-05 | Nagase Chemtex Corp | 高尿酸血症、又は痛風の予防、改善、又は治療剤 |
US20100105139A1 (en) | 2008-10-27 | 2010-04-29 | Remco Alexander Spanjaard | Ligand Targeted Nanocapsules for the delivery of RNAi and other Agents |
RU2011136624A (ru) | 2009-02-05 | 2013-03-10 | Тарджетед Деливери Текнолоджиз Лимитед | Способы уменьшения пролиферации и жизнеспособности микробных агентов |
CN105434354A (zh) | 2009-06-03 | 2016-03-30 | 斯昆申技术控股有限责任公司 | 用于治疗深部组织疼痛的制剂 |
CN102770162B (zh) | 2009-08-21 | 2016-09-28 | 靶向递送技术有限公司 | 囊泡制剂 |
EP2382994A1 (en) | 2010-04-26 | 2011-11-02 | Maurizio Victor Cattaneo | Ligand targeted nanocapsules for the delivery of RNAi and other agents |
US8741373B2 (en) | 2010-06-21 | 2014-06-03 | Virun, Inc. | Compositions containing non-polar compounds |
US20120045405A1 (en) | 2010-08-18 | 2012-02-23 | Gilman Miles E | Under eye cream |
GB201206486D0 (en) | 2012-04-12 | 2012-05-30 | Sequessome Technology Holdings Ltd | Vesicular formulations and uses thereof |
GB201208409D0 (en) | 2012-05-14 | 2012-06-27 | Sequessome Technology Holdings Ltd | Vesicular formulations, kits and uses |
GB201208384D0 (en) | 2012-05-14 | 2012-06-27 | Sequessome Technology Holdings Ltd | Vesicular formulations, uses and methods |
CN105473162A (zh) | 2013-07-31 | 2016-04-06 | 斯昆申技术控股有限责任公司 | 囊泡 |
-
2012
- 2012-03-29 GB GBGB1205642.0A patent/GB201205642D0/en not_active Ceased
-
2013
- 2013-03-28 EP EP13712801.3A patent/EP2830630A1/en not_active Ceased
- 2013-03-28 MX MX2014011516A patent/MX2014011516A/es unknown
- 2013-03-28 EA EA201491581A patent/EA038899B1/ru unknown
- 2013-03-28 BR BR112014024033A patent/BR112014024033A8/pt not_active IP Right Cessation
- 2013-03-28 KR KR1020147027498A patent/KR20150004798A/ko not_active Application Discontinuation
- 2013-03-28 CA CA2867749A patent/CA2867749A1/en not_active Abandoned
- 2013-03-28 SG SG11201406144TA patent/SG11201406144TA/en unknown
- 2013-03-28 IN IN7913DEN2014 patent/IN2014DN07913A/en unknown
- 2013-03-28 CN CN201380027033.9A patent/CN104349782A/zh active Pending
- 2013-03-28 WO PCT/EP2013/056694 patent/WO2013144289A1/en active Application Filing
- 2013-03-28 JP JP2015502351A patent/JP2015511618A/ja active Pending
- 2013-03-28 NZ NZ700472A patent/NZ700472A/en unknown
- 2013-03-28 GB GB1419075.5A patent/GB2515440B/en active Active
- 2013-03-28 US US14/388,469 patent/US9555051B2/en active Active
- 2013-03-28 AU AU2013241701A patent/AU2013241701A1/en not_active Abandoned
-
2014
- 2014-09-17 PH PH12014502065A patent/PH12014502065A1/en unknown
- 2014-09-18 IL IL234747A patent/IL234747A0/en unknown
- 2014-09-25 CL CL2014002547A patent/CL2014002547A1/es unknown
- 2014-10-28 CO CO14238690A patent/CO7121334A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
CA2867749A1 (en) | 2013-10-03 |
PH12014502065A1 (en) | 2014-12-10 |
GB201205642D0 (en) | 2012-05-16 |
WO2013144289A1 (en) | 2013-10-03 |
US9555051B2 (en) | 2017-01-31 |
AU2013241701A1 (en) | 2014-10-16 |
US20150057249A1 (en) | 2015-02-26 |
IN2014DN07913A (pt) | 2015-04-24 |
EA201491581A1 (ru) | 2015-02-27 |
EP2830630A1 (en) | 2015-02-04 |
GB201419075D0 (en) | 2014-12-10 |
EA038899B1 (ru) | 2021-11-03 |
GB2515440A (en) | 2014-12-24 |
IL234747A0 (en) | 2014-11-30 |
SG11201406144TA (en) | 2014-10-30 |
CN104349782A (zh) | 2015-02-11 |
MX2014011516A (es) | 2015-04-08 |
CO7121334A2 (es) | 2014-11-20 |
GB2515440B (en) | 2017-02-08 |
NZ700472A (en) | 2016-02-26 |
KR20150004798A (ko) | 2015-01-13 |
BR112014024033A2 (pt) | 2017-06-20 |
CL2014002547A1 (es) | 2015-03-27 |
JP2015511618A (ja) | 2015-04-20 |
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