EA201690914A1 - Новое соединение для лечения тяжелой гипогликемии - Google Patents

Новое соединение для лечения тяжелой гипогликемии

Info

Publication number
EA201690914A1
EA201690914A1 EA201690914A EA201690914A EA201690914A1 EA 201690914 A1 EA201690914 A1 EA 201690914A1 EA 201690914 A EA201690914 A EA 201690914A EA 201690914 A EA201690914 A EA 201690914A EA 201690914 A1 EA201690914 A1 EA 201690914A1
Authority
EA
Eurasian Patent Office
Prior art keywords
hypoglycemia
heavy
treatment
new connection
new
Prior art date
Application number
EA201690914A
Other languages
English (en)
Inventor
Хорхе Алсина-Фернандес
Роберт Чадвик Камминс
Лили Гуо
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of EA201690914A1 publication Critical patent/EA201690914A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

В настоящем изобретении предложено новое соединение, применяемое для лечения гипогликемии.
EA201690914A 2013-12-18 2014-12-11 Новое соединение для лечения тяжелой гипогликемии EA201690914A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361917597P 2013-12-18 2013-12-18
PCT/US2014/069643 WO2015094875A1 (en) 2013-12-18 2014-12-11 Novel compound for treatment of severe hypoglycemia

Publications (1)

Publication Number Publication Date
EA201690914A1 true EA201690914A1 (ru) 2016-09-30

Family

ID=52278802

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201690914A EA201690914A1 (ru) 2013-12-18 2014-12-11 Новое соединение для лечения тяжелой гипогликемии

Country Status (27)

Country Link
US (1) US9695225B2 (ru)
EP (1) EP3083668A1 (ru)
JP (1) JP2017509584A (ru)
KR (1) KR20160075825A (ru)
CN (1) CN105814076A (ru)
AP (1) AP2016009242A0 (ru)
AR (1) AR098614A1 (ru)
AU (1) AU2014366424B2 (ru)
BR (1) BR112016012067A2 (ru)
CA (1) CA2928985A1 (ru)
CL (1) CL2016001472A1 (ru)
CR (1) CR20160226A (ru)
DO (1) DOP2016000096A (ru)
EA (1) EA201690914A1 (ru)
EC (1) ECSP16024798A (ru)
GT (1) GT201600117A (ru)
HK (1) HK1224304A1 (ru)
IL (1) IL245400A0 (ru)
MA (1) MA39109B1 (ru)
MX (1) MX2016007982A (ru)
NZ (1) NZ719463A (ru)
PE (1) PE20160848A1 (ru)
PH (1) PH12016501182A1 (ru)
SG (1) SG11201604154SA (ru)
TN (1) TN2016000181A1 (ru)
TW (1) TW201609127A (ru)
WO (1) WO2015094875A1 (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI622596B (zh) 2015-10-26 2018-05-01 美國禮來大藥廠 升糖素受體促效劑
WO2019140024A1 (en) 2018-01-12 2019-07-18 Eli Lilly And Company Combination therapy
WO2020163125A1 (en) 2019-02-05 2020-08-13 Eli Lilly And Company Glucagon analog agonists and methods of using the same

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006258841B2 (en) 2005-06-13 2012-05-03 Imperial Innovations Limited Oxyntomodulin analogues and their effects on feeding behaviour
WO2008086086A2 (en) 2007-01-05 2008-07-17 Indiana University Research And Technology Corporation Glucagon analogs exhibiting enhanced solubility in physiological ph buffers
US20090098130A1 (en) * 2007-01-05 2009-04-16 Bradshaw Curt W Glucagon-like protein-1 receptor (glp-1r) agonist compounds
ES2650038T3 (es) 2008-06-17 2018-01-16 Indiana University Research And Technology Corporation Agonistas mixtos a base de GIP para el tratamiento de trastornos metabólicos y obesidad
JP5753779B2 (ja) * 2008-06-17 2015-07-22 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションＩｎｄｉａｎａ Ｕｎｉｖｅｒｓｉｔｙ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ 生理学的ｐＨの緩衝液中で向上した溶解性及び安定性を示すグルカゴン類縁体
JP5887265B2 (ja) 2009-06-16 2016-03-16 インディアナ・ユニバーシティ・リサーチ・アンド・テクノロジー・コーポレーション Ｇｉｐ受容体活性グルカゴン化合物
US20120148586A1 (en) * 2009-08-27 2012-06-14 Joyce Ching Tsu Chou Glucagon-like protein-1 receptor (glp-1r) agonists for treating autoimmune disorders
EP2512503A4 (en) 2009-12-18 2013-08-21 Univ Indiana Res & Tech Corp COAGONISTS OF GLUCAGON / GLP-1 RECEPTOR
BR112012028707A2 (pt) * 2010-05-13 2019-09-24 Univ Indiana Res & Tech Corp composto de glucagon da superfamília de peptídeos exibindo atividade do receptor g com proteína acoplada, pró farmaco, dímero ou multímro, composição farmacêutica que o compreendem e método de administração do mesmo.
EA201390941A1 (ru) 2010-12-22 2013-12-30 Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн Аналоги глюкагона, проявляющие активность на рецепторе gip
DK3434687T3 (da) * 2011-06-10 2021-06-07 Hanmi Science Co Ltd Hidtil ukendte oxyntomodulinderivater og farmaceutisk præparat til behandling af fedme omfattende samme
US9309301B2 (en) 2011-06-22 2016-04-12 Indiana University Research And Technology Corporation Glucagon/GLP-1 receptor co-agonists
WO2013004983A1 (en) * 2011-07-04 2013-01-10 Imperial Innovations Limited Novel compounds and their effects on feeding behaviour
MX2014015558A (es) * 2012-06-21 2015-03-05 Univ Indiana Res & Tech Corp Analogos de glucagon que exhiben actividad del receptor gip.

Also Published As

Publication number Publication date
US20160311881A1 (en) 2016-10-27
IL245400A0 (en) 2016-06-30
KR20160075825A (ko) 2016-06-29
PE20160848A1 (es) 2016-09-10
AP2016009242A0 (en) 2016-06-30
AR098614A1 (es) 2016-06-01
US9695225B2 (en) 2017-07-04
MX2016007982A (es) 2016-09-09
ECSP16024798A (es) 2017-05-31
SG11201604154SA (en) 2016-07-28
AU2014366424B2 (en) 2017-02-16
AU2014366424A1 (en) 2016-05-19
CA2928985A1 (en) 2015-06-25
NZ719463A (en) 2017-09-29
CN105814076A (zh) 2016-07-27
JP2017509584A (ja) 2017-04-06
CL2016001472A1 (es) 2017-03-10
DOP2016000096A (es) 2016-08-15
WO2015094875A1 (en) 2015-06-25
MA39109A1 (fr) 2017-09-29
CR20160226A (es) 2016-07-12
PH12016501182A1 (en) 2016-07-25
TW201609127A (zh) 2016-03-16
TN2016000181A1 (en) 2017-10-06
HK1224304A1 (zh) 2017-08-18
BR112016012067A2 (pt) 2017-09-26
MA39109B1 (fr) 2018-04-30
GT201600117A (es) 2017-07-06
EP3083668A1 (en) 2016-10-26

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