EA201490677A1 - Связывающие антиген cd27l белки - Google Patents

Связывающие антиген cd27l белки

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Publication number
EA201490677A1
EA201490677A1 EA201490677A EA201490677A EA201490677A1 EA 201490677 A1 EA201490677 A1 EA 201490677A1 EA 201490677 A EA201490677 A EA 201490677A EA 201490677 A EA201490677 A EA 201490677A EA 201490677 A1 EA201490677 A1 EA 201490677A1
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EA
Eurasian Patent Office
Prior art keywords
cd27l
proteins
antigen
bonding
antigen binding
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Application number
EA201490677A
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English (en)
Other versions
EA027900B1 (ru
Inventor
Джон М. Делейни
Уилльям Кристиан Фэнслоу Iii
Чэдвик Теренс Кинг
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Эмджен Инк.
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Application filed by Эмджен Инк. filed Critical Эмджен Инк.
Publication of EA201490677A1 publication Critical patent/EA201490677A1/ru
Publication of EA027900B1 publication Critical patent/EA027900B1/ru

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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
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    • A61K47/6851Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
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    • C07K16/2875Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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Abstract

Изобретение относится к связывающим антиген CD27L белкам, таким как антитела, полинуклеотидам, кодирующим указанные связывающие антиген CD27L белки, композициям конъюгатов лекарственное соединение - антитело и способам диагностики и лечения заболеваний, связанных с экспрессией CD27L.
EA201490677A 2011-09-22 2012-09-20 Связывающие антиген cd27l белки EA027900B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161538024P 2011-09-22 2011-09-22
PCT/US2012/056429 WO2013043933A2 (en) 2011-09-22 2012-09-20 Cd27l antigen binding proteins

Publications (2)

Publication Number Publication Date
EA201490677A1 true EA201490677A1 (ru) 2014-08-29
EA027900B1 EA027900B1 (ru) 2017-09-29

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ID=46964100

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201790757A EA201790757A1 (ru) 2011-09-22 2012-09-20 Связывающие антиген cd27l белки
EA201490677A EA027900B1 (ru) 2011-09-22 2012-09-20 Связывающие антиген cd27l белки

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EA201790757A EA201790757A1 (ru) 2011-09-22 2012-09-20 Связывающие антиген cd27l белки

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US (3) US8987422B2 (ru)
EP (1) EP2758437B1 (ru)
JP (2) JP6251678B2 (ru)
KR (1) KR102007055B1 (ru)
CN (1) CN104136461B (ru)
AP (1) AP2014007588A0 (ru)
AR (1) AR093186A1 (ru)
AU (2) AU2012312274B2 (ru)
BR (1) BR112014006822B1 (ru)
CA (1) CA2849318C (ru)
CL (2) CL2014000699A1 (ru)
CO (1) CO7020862A2 (ru)
CR (1) CR20140169A (ru)
EA (2) EA201790757A1 (ru)
ES (1) ES2806146T3 (ru)
HK (1) HK1199042A1 (ru)
IL (1) IL231603B (ru)
JO (1) JO3625B1 (ru)
MX (1) MX353958B (ru)
MY (1) MY173865A (ru)
PE (1) PE20141151A1 (ru)
SG (2) SG11201400859SA (ru)
TN (1) TN2014000120A1 (ru)
TW (2) TWI579298B (ru)
UA (1) UA118332C2 (ru)
UY (1) UY34343A (ru)
WO (1) WO2013043933A2 (ru)
ZA (1) ZA201402258B (ru)

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