EA201291039A1 - Антитела, связывающие cd27 человека, и их применение - Google Patents

Антитела, связывающие cd27 человека, и их применение

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Publication number
EA201291039A1
EA201291039A1 EA201291039A EA201291039A EA201291039A1 EA 201291039 A1 EA201291039 A1 EA 201291039A1 EA 201291039 A EA201291039 A EA 201291039A EA 201291039 A EA201291039 A EA 201291039A EA 201291039 A1 EA201291039 A1 EA 201291039A1
Authority
EA
Eurasian Patent Office
Prior art keywords
antibodies
human
application
bind
diagnosis
Prior art date
Application number
EA201291039A
Other languages
English (en)
Other versions
EA024701B1 (ru
Inventor
Тибор Келер
Генри К. Марш
Личжэнь Хе
Лаура А. Витале
Лоренс Дж. Томас
Original Assignee
Селлдекс Терапьютикс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44534592&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201291039(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Селлдекс Терапьютикс Инк. filed Critical Селлдекс Терапьютикс Инк.
Publication of EA201291039A1 publication Critical patent/EA201291039A1/ru
Publication of EA024701B1 publication Critical patent/EA024701B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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Abstract

Описаны выделенные моноклональные антитела, связывающиеся с CD27 человека, и связанные с ними композиции и молекулы на основе антител. Кроме того, описаны также способы лечения и диагностики с использованием указанных антител.
EA201291039A 2010-04-13 2011-04-13 Антитела, связывающие cd27 человека, и их применение EA024701B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32372010P 2010-04-13 2010-04-13
US201161471459P 2011-04-04 2011-04-04
PCT/US2011/032355 WO2011130434A2 (en) 2010-04-13 2011-04-13 Antibodies that bind human cd27 and uses thereof

Publications (2)

Publication Number Publication Date
EA201291039A1 true EA201291039A1 (ru) 2013-04-30
EA024701B1 EA024701B1 (ru) 2016-10-31

Family

ID=44534592

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201690310A EA201690310A1 (ru) 2010-04-13 2011-04-13 Антитела, связывающие cd27 человека, и их применение
EA201291039A EA024701B1 (ru) 2010-04-13 2011-04-13 Антитела, связывающие cd27 человека, и их применение

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EA201690310A EA201690310A1 (ru) 2010-04-13 2011-04-13 Антитела, связывающие cd27 человека, и их применение

Country Status (15)

Country Link
US (3) US9169325B2 (ru)
EP (2) EP3165540A1 (ru)
JP (2) JP6002659B2 (ru)
KR (1) KR101958753B1 (ru)
CN (2) CN103154034B (ru)
AU (1) AU2011239706B2 (ru)
BR (1) BR112012026227A2 (ru)
CA (1) CA2796571C (ru)
EA (2) EA201690310A1 (ru)
ES (1) ES2608475T3 (ru)
IL (1) IL222329B (ru)
MX (1) MX339621B (ru)
NZ (2) NZ602892A (ru)
SG (1) SG184310A1 (ru)
WO (1) WO2011130434A2 (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2730665C2 (ru) * 2014-11-10 2020-08-24 Медиммун Лимитед Связывающие молекулы, специфичные в отношении CD73, и пути их применения

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ602892A (en) 2010-04-13 2014-08-29 Celldex Therapeutics Inc Antibodies that bind human cd27 and uses thereof
AU2011275749C1 (en) * 2010-07-09 2015-09-17 Aduro Biotech Holdings, Europe B.V. Agonistic antibody to CD27
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