EA201100699A1 - Способ получения альфа-токотриенола и его производных - Google Patents

Способ получения альфа-токотриенола и его производных

Info

Publication number
EA201100699A1
EA201100699A1 EA201100699A EA201100699A EA201100699A1 EA 201100699 A1 EA201100699 A1 EA 201100699A1 EA 201100699 A EA201100699 A EA 201100699A EA 201100699 A EA201100699 A EA 201100699A EA 201100699 A1 EA201100699 A1 EA 201100699A1
Authority
EA
Eurasian Patent Office
Prior art keywords
tokotrienol
derivatives
producing alpha
tocotrienol
alpha
Prior art date
Application number
EA201100699A
Other languages
English (en)
Other versions
EA026417B1 (ru
Inventor
Кирон Е. Вессон
Эндрю В. Хинман
Орион Д. Янковски
Original Assignee
Эдисон Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эдисон Фармасьютикалз, Инк. filed Critical Эдисон Фармасьютикалз, Инк.
Publication of EA201100699A1 publication Critical patent/EA201100699A1/ru
Publication of EA026417B1 publication Critical patent/EA026417B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C07C46/06—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Изобретение раскрывает новые способы получения, обогащения и/или выделения альфа-токотриенола из исходного материала, включающего по меньшей мере один токотриенол, не представляющий собой альфа-токотриенол, такого как природные экстракты, включающие смешанные токотриенолы.
EA201100699A 2008-10-28 2009-10-27 СПОСОБ ПОЛУЧЕНИЯ α-ТОКОТРИЕНОЛА И ЕГО ПРОИЗВОДНЫХ EA026417B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19758508P 2008-10-28 2008-10-28
PCT/US2009/062212 WO2010051277A1 (en) 2008-10-28 2009-10-27 Process for the production of alpha-tocotrienol and derivatives

Publications (2)

Publication Number Publication Date
EA201100699A1 true EA201100699A1 (ru) 2011-12-30
EA026417B1 EA026417B1 (ru) 2017-04-28

Family

ID=42118126

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201100699A EA026417B1 (ru) 2008-10-28 2009-10-27 СПОСОБ ПОЛУЧЕНИЯ α-ТОКОТРИЕНОЛА И ЕГО ПРОИЗВОДНЫХ
EA201692046A EA201692046A1 (ru) 2008-10-28 2009-10-27 СПОСОБ ПОЛУЧЕНИЯ α-ТОКОТРИЕНОЛА И ЕГО ПРОИЗВОДНЫХ

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA201692046A EA201692046A1 (ru) 2008-10-28 2009-10-27 СПОСОБ ПОЛУЧЕНИЯ α-ТОКОТРИЕНОЛА И ЕГО ПРОИЗВОДНЫХ

Country Status (18)

Country Link
US (6) US8106223B2 (ru)
EP (3) EP2362875B1 (ru)
JP (7) JP5775459B2 (ru)
CN (2) CN102264730B (ru)
BR (1) BRPI0920414B1 (ru)
CA (2) CA2974482C (ru)
DK (2) DK2963006T3 (ru)
EA (2) EA026417B1 (ru)
ES (2) ES2553557T3 (ru)
HK (2) HK1161876A1 (ru)
HU (1) HUE041714T2 (ru)
MX (1) MX2011004440A (ru)
MY (2) MY185183A (ru)
PL (2) PL2362875T3 (ru)
PT (2) PT2963006T (ru)
SI (1) SI2963006T1 (ru)
TR (1) TR201819154T4 (ru)
WO (1) WO2010051277A1 (ru)

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US20100105930A1 (en) 2010-04-29
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