EA201100268A1 - Вакцина - Google Patents
ВакцинаInfo
- Publication number
- EA201100268A1 EA201100268A1 EA201100268A EA201100268A EA201100268A1 EA 201100268 A1 EA201100268 A1 EA 201100268A1 EA 201100268 A EA201100268 A EA 201100268A EA 201100268 A EA201100268 A EA 201100268A EA 201100268 A1 EA201100268 A1 EA 201100268A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- antigen
- vaccine
- particle
- delivery
- combined
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6018—Lipids, e.g. in lipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15071—Demonstrated in vivo effect
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
В данном изобретении предлагается иммуногенная композиция, содержащая по меньшей мере одну частицу для доставки антигена и по меньшей мере один антиген, где антиген и частицу для доставки антигена соединяют, используя промежуточный линкер.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9258208P | 2008-08-28 | 2008-08-28 | |
US9574708P | 2008-10-15 | 2008-10-15 | |
US16568809P | 2009-04-01 | 2009-04-01 | |
PCT/EP2009/060967 WO2010023216A1 (en) | 2008-08-28 | 2009-08-26 | Vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201100268A1 true EA201100268A1 (ru) | 2011-10-31 |
Family
ID=41338517
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201100268A EA201100268A1 (ru) | 2008-08-28 | 2009-08-26 | Вакцина |
Country Status (13)
Country | Link |
---|---|
US (1) | US8846080B2 (ru) |
EP (1) | EP2328613A1 (ru) |
JP (2) | JP5769624B2 (ru) |
KR (1) | KR20110050531A (ru) |
CN (1) | CN102202689A (ru) |
AU (1) | AU2009286769A1 (ru) |
BR (1) | BRPI0916884A2 (ru) |
CA (1) | CA2734950A1 (ru) |
EA (1) | EA201100268A1 (ru) |
IL (1) | IL211233A0 (ru) |
MX (1) | MX2011002267A (ru) |
WO (1) | WO2010023216A1 (ru) |
ZA (1) | ZA201101481B (ru) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUE031380T2 (en) * | 2005-06-27 | 2017-07-28 | Glaxosmithkline Biologicals Sa | A method for producing vaccines |
US9308253B2 (en) * | 2011-09-19 | 2016-04-12 | The Johns Hopkins University | Cancer immunotherapy |
DK3311827T3 (da) | 2011-10-03 | 2023-04-03 | Canqura Oncology Ab | Nanopartikler, fremgangsmåde til fremstilling og anvendelse deraf som bærere for amfipatiske eller hydrofobe molekyler inden for det medicinske område, inklusiv cancerbehandling, samt fødevarerelaterede forbindelser |
GB201120000D0 (en) * | 2011-11-20 | 2012-01-04 | Glaxosmithkline Biolog Sa | Vaccine |
US9956276B2 (en) | 2012-01-19 | 2018-05-01 | Duke University | Vaccines against antigens involved in therapy resistance and methods of using same |
AU2014292926B2 (en) | 2013-07-25 | 2020-03-05 | Exicure Operating Company | Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use |
CA2932122C (en) * | 2013-12-03 | 2022-04-19 | Northwestern University | Liposomal particles, methods of making same and uses thereof |
PL3164113T3 (pl) | 2014-06-04 | 2019-09-30 | Exicure, Inc. | Wielowartościowe dostarczanie modulatorów immunologicznych w liposomowych kolistych kwasach nukleinowych do zastosowań profilaktycznych lub terapeutycznych |
CA2954279C (en) | 2014-07-07 | 2023-11-14 | Duke University | Vaccines against an oncogenic isoform of esr1 and methods of using the same |
WO2016007499A1 (en) | 2014-07-07 | 2016-01-14 | Duke University | Vaccines against an oncogenic isoform of her2 (erbb2) and methods of using the same |
US9775898B2 (en) | 2015-02-26 | 2017-10-03 | Thevax Genetics Vaccine Co., Ltd. | Vaccine composition comprising an immunogenic protein and combination adjuvants for use in eliciting antigen-specific T-cell responses |
WO2017057540A1 (ja) * | 2015-09-30 | 2017-04-06 | 塩野義製薬株式会社 | 免疫賦活活性を有する核酸誘導体 |
US10940201B2 (en) | 2015-09-30 | 2021-03-09 | Shionogi & Co., Ltd. | Nucleic acid derivative having immunostimulatory activity |
CN108697779B (zh) | 2016-01-07 | 2023-09-19 | 杜克大学 | 癌症疫苗和递送方法 |
WO2017200957A1 (en) * | 2016-05-16 | 2017-11-23 | Infectious Disease Research Institute | Pegylated liposomes and methods of use |
US11364304B2 (en) | 2016-08-25 | 2022-06-21 | Northwestern University | Crosslinked micellar spherical nucleic acids |
US10058606B2 (en) | 2016-09-19 | 2018-08-28 | Thevax Genetics Vaccine Co., Ltd. | Hepatitis B therapeutic vaccines |
US11224665B2 (en) | 2016-10-05 | 2022-01-18 | Duke University | Mitochondrial antiviral signaling (MAVS) protein compositions and methods of using the same |
US10487143B2 (en) | 2016-10-05 | 2019-11-26 | Duke University | Vaccines against HER3 antigens and methods of using the same |
SG11201908059YA (en) * | 2017-03-29 | 2019-10-30 | Shionogi & Co | Nucleic acid derivative having immunostimulatory activity |
MX2020000387A (es) | 2017-07-13 | 2020-08-17 | Univ Northwestern | Método general y directo para preparar nanopartículas de estructura organometálica funcionalizadas con oligonucleotidos. |
CN111551729B (zh) * | 2020-04-27 | 2021-02-09 | 浙江正熙生物技术股份有限公司 | 藻红蛋白免疫荧光探针制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2423335T3 (da) * | 2001-06-21 | 2014-08-18 | Dynavax Tech Corp | Kimæriske immunmodulatoriske forbindelser og fremgangsmåder til anvendelse deraf |
US7785610B2 (en) * | 2001-06-21 | 2010-08-31 | Dynavax Technologies Corporation | Chimeric immunomodulatory compounds and methods of using the same—III |
ES2295836T3 (es) * | 2003-03-13 | 2008-04-16 | Glaxosmithkline Biologicals S.A. | Procedimiento de purificacion de citolisina bacteriana. |
AU2004275876B2 (en) * | 2003-09-25 | 2011-03-31 | Coley Pharmaceutical Gmbh | Nucleic acid-lipophilic conjugates |
JP2007530449A (ja) * | 2003-12-08 | 2007-11-01 | イデラ ファーマシューティカルズ インコーポレイテッド | 小オリゴヌクレオチドに基づく化合物による免疫刺激特性の調節 |
US20070129320A9 (en) * | 2004-07-18 | 2007-06-07 | Coley Pharmaceutical Group, Ltd. | Methods and compositions for inducing innate immune responses |
GB0427131D0 (en) * | 2004-12-10 | 2005-01-12 | Glaxosmithkline Biolog Sa | Novel combination |
JP2008524237A (ja) * | 2004-12-17 | 2008-07-10 | ダイナバックス テクノロジーズ コーポレイション | 免疫寛容の誘導又は促進のための方法及び組成物 |
HUE031380T2 (en) * | 2005-06-27 | 2017-07-28 | Glaxosmithkline Biologicals Sa | A method for producing vaccines |
-
2009
- 2009-08-26 KR KR1020117006905A patent/KR20110050531A/ko not_active Application Discontinuation
- 2009-08-26 US US13/060,301 patent/US8846080B2/en not_active Expired - Fee Related
- 2009-08-26 WO PCT/EP2009/060967 patent/WO2010023216A1/en active Application Filing
- 2009-08-26 CN CN2009801437446A patent/CN102202689A/zh active Pending
- 2009-08-26 JP JP2011524363A patent/JP5769624B2/ja not_active Expired - Fee Related
- 2009-08-26 BR BRPI0916884A patent/BRPI0916884A2/pt not_active IP Right Cessation
- 2009-08-26 MX MX2011002267A patent/MX2011002267A/es not_active Application Discontinuation
- 2009-08-26 EA EA201100268A patent/EA201100268A1/ru unknown
- 2009-08-26 EP EP09782191A patent/EP2328613A1/en not_active Withdrawn
- 2009-08-26 CA CA2734950A patent/CA2734950A1/en active Pending
- 2009-08-26 AU AU2009286769A patent/AU2009286769A1/en not_active Abandoned
-
2011
- 2011-02-15 IL IL211233A patent/IL211233A0/en unknown
- 2011-02-24 ZA ZA2011/01481A patent/ZA201101481B/en unknown
-
2015
- 2015-04-09 JP JP2015079662A patent/JP2015163617A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2015163617A (ja) | 2015-09-10 |
JP2012500827A (ja) | 2012-01-12 |
BRPI0916884A2 (pt) | 2016-06-14 |
CA2734950A1 (en) | 2010-03-04 |
IL211233A0 (en) | 2011-04-28 |
WO2010023216A1 (en) | 2010-03-04 |
MX2011002267A (es) | 2011-03-30 |
US8846080B2 (en) | 2014-09-30 |
EP2328613A1 (en) | 2011-06-08 |
CN102202689A (zh) | 2011-09-28 |
AU2009286769A1 (en) | 2010-03-04 |
US20110159081A1 (en) | 2011-06-30 |
ZA201101481B (en) | 2012-07-25 |
JP5769624B2 (ja) | 2015-08-26 |
KR20110050531A (ko) | 2011-05-13 |
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