EA201071329A1 - Диамидные производные адамантана и их применение - Google Patents

Диамидные производные адамантана и их применение

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Publication number
EA201071329A1
EA201071329A1 EA201071329A EA201071329A EA201071329A1 EA 201071329 A1 EA201071329 A1 EA 201071329A1 EA 201071329 A EA201071329 A EA 201071329A EA 201071329 A EA201071329 A EA 201071329A EA 201071329 A1 EA201071329 A1 EA 201071329A1
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EA
Eurasian Patent Office
Prior art keywords
derivatives
adamantania
diamid
application
adamanane
Prior art date
Application number
EA201071329A
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English (en)
Other versions
EA019546B1 (ru
Inventor
Эрмогенес Н. Хименес
Гуйин Ли
Дарио Доллер
Мишель Гренон
Эндрю Д. Уайт
Маоцзюнь Го
Гил Ма
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Х. Лундбекк А/С
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Application filed by Х. Лундбекк А/С filed Critical Х. Лундбекк А/С
Publication of EA201071329A1 publication Critical patent/EA201071329A1/ru
Publication of EA019546B1 publication Critical patent/EA019546B1/ru

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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

Abstract

Настоящее изобретение относится к диамидным производным адаманана формулы (I)где Rи Rимеют указанные здесь значения, или их фармацевтически приемлемым солям; а также к фармацевтическим композициям и способам их применения.
EA201071329A 2008-07-25 2009-07-17 Диамидные производные адамантана, содержащая их фармацевтическая композиция и их применение EA019546B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8356308P 2008-07-25 2008-07-25
US16080409P 2009-03-17 2009-03-17
PCT/US2009/050934 WO2010011570A1 (en) 2008-07-25 2009-07-17 Adamantyl diamide derivatives and uses of same

Publications (2)

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EA201071329A1 true EA201071329A1 (ru) 2011-06-30
EA019546B1 EA019546B1 (ru) 2014-04-30

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JP (1) JP5572625B2 (ru)
KR (1) KR20110036797A (ru)
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US7947680B2 (en) 2008-07-25 2011-05-24 H. Lundbeck A/S Adamantyl diamide derivatives and uses of same
JP5693452B2 (ja) * 2008-08-04 2015-04-01 シーエイチディーアイ ファウンデーション，インコーポレーテッド 特定のキヌレニン−３−モノオキシゲナーゼインヒビター、医薬組成物およびそれらの使用方法
KR20110123657A (ko) * 2010-05-07 2011-11-15 에스케이케미칼주식회사 피콜린아마이드 및 피리미딘-4-카복사미드 화합물, 이의 제조방법 및 이를 함유하는 약제학적 조성물
WO2012062750A1 (en) * 2010-11-08 2012-05-18 Janssen Pharmaceuticals, Inc. 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
TWI538905B (zh) * 2010-12-22 2016-06-21 Ｈ 朗德貝克公司 雙環［３．２．１］辛基醯胺衍生物及其用途
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