EA200700703A1 - Гранулярные препараты габоксадола - Google Patents

Гранулярные препараты габоксадола

Info

Publication number
EA200700703A1
EA200700703A1 EA200700703A EA200700703A EA200700703A1 EA 200700703 A1 EA200700703 A1 EA 200700703A1 EA 200700703 A EA200700703 A EA 200700703A EA 200700703 A EA200700703 A EA 200700703A EA 200700703 A1 EA200700703 A1 EA 200700703A1
Authority
EA
Eurasian Patent Office
Prior art keywords
hoboxadol
granular preparations
gaboxadol
granular
melting
Prior art date
Application number
EA200700703A
Other languages
English (en)
Inventor
Михиль Онне Элема
Лене Андресен
Пер Хольм
Original Assignee
Х.Лундбекк А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Х.Лундбекк А/С filed Critical Х.Лундбекк А/С
Publication of EA200700703A1 publication Critical patent/EA200700703A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Настоящее изобретение относится к гранулированному продукту, содержащему габоксадол в виде аддитивной соли кислоты, к способу гранулирования путем расплавления для его получения и к твердым фармацевтическим стандартным дозированным формам, получаемым из указанного гранулярного препарата габоксадола.
EA200700703A 2001-05-21 2002-05-17 Гранулярные препараты габоксадола EA200700703A1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200100817 2001-05-21

Publications (1)

Publication Number Publication Date
EA200700703A1 true EA200700703A1 (ru) 2007-08-31

Family

ID=8160520

Family Applications (2)

Application Number Title Priority Date Filing Date
EA200700703A EA200700703A1 (ru) 2001-05-21 2002-05-17 Гранулярные препараты габоксадола
EA200301282A EA009731B1 (ru) 2001-05-21 2002-05-17 Гранулярные препараты габоксадола

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA200301282A EA009731B1 (ru) 2001-05-21 2002-05-17 Гранулярные препараты габоксадола

Country Status (26)

Country Link
US (1) US20040157876A1 (ru)
EP (1) EP1389091A1 (ru)
JP (1) JP2004530695A (ru)
KR (1) KR20030097890A (ru)
CN (1) CN1511026A (ru)
AR (1) AR033896A1 (ru)
AU (1) AU2002338855B2 (ru)
BG (1) BG108441A (ru)
BR (1) BR0209834A (ru)
CA (1) CA2447603A1 (ru)
CZ (1) CZ20033269A3 (ru)
EA (2) EA200700703A1 (ru)
HR (1) HRP20030950A2 (ru)
HU (1) HUP0400051A2 (ru)
IL (1) IL158733A0 (ru)
IS (1) IS7020A (ru)
ME (1) MEP6308A (ru)
MX (1) MXPA03010596A (ru)
NO (1) NO20035146D0 (ru)
NZ (1) NZ547636A (ru)
PL (1) PL366541A1 (ru)
SK (1) SK15542003A3 (ru)
UA (1) UA80092C2 (ru)
WO (1) WO2002094225A1 (ru)
YU (1) YU92103A (ru)
ZA (1) ZA200308594B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2385749A1 (en) * 1999-09-28 2001-04-05 H. Lundbeck A/S Melt granulated composition and modified release dosage form prepared from said composition
PL1641456T3 (pl) 2003-06-25 2010-08-31 H Lundbeck As Gaboksadol do leczenia depresji i innych zaburzeń afektywnych
TW200528098A (en) * 2003-12-18 2005-09-01 Lundbeck & Co As H Treatment of insomnia in human patients
GB0402118D0 (en) 2004-01-30 2004-03-03 Merck Sharp & Dohme Polymorphic forms of a GABAA agonist
EP2292222A1 (en) 2005-01-28 2011-03-09 H. Lundbeck A/S Polymorphic Forms of a GABAA Agonist
EP1906953A4 (en) * 2005-04-29 2009-05-20 Lundbeck & Co As H FORMS OF ACID SALTS AND BASIC SALTS OF GABOXADOL
JP5792061B2 (ja) * 2008-05-30 2015-10-07 サイコジェニックス・インコーポレーテッドＰｓｙｃｈｏｇｅｎｉｃｓ Ｉｎｃ． 神経及び精神障害の治療法
CA2732636A1 (en) * 2008-09-01 2009-05-07 H. Lundbeck A/S Pharmaceutical composition comprising gaboxadol and an inhibitor of pat1 or oat
WO2013090452A1 (en) 2011-12-12 2013-06-20 Orbis Biosciences, Inc. Sustained release particle formulations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4315934A (en) * 1979-09-24 1982-02-16 Sandoz Ltd. Organic compounds
DE19525598C2 (de) * 1995-07-13 1997-09-25 Max Planck Gesellschaft Schlafmittel
US6649186B1 (en) * 1996-09-20 2003-11-18 Ethypharm Effervescent granules and methods for their preparation
CA2385749A1 (en) * 1999-09-28 2001-04-05 H. Lundbeck A/S Melt granulated composition and modified release dosage form prepared from said composition
US6375982B1 (en) * 2000-07-05 2002-04-23 Capricorn Pharma, Inc. Rapid-melt semi-solid compositions, methods of making same and method of using same

Also Published As

Publication number Publication date
WO2002094225A1 (en) 2002-11-28
NZ547636A (en) 2008-03-28
AR033896A1 (es) 2004-01-07
EA200301282A1 (ru) 2004-04-29
IL158733A0 (en) 2004-05-12
CA2447603A1 (en) 2002-11-28
BG108441A (en) 2005-02-28
AU2002338855B2 (en) 2007-08-16
UA80092C2 (en) 2007-08-27
PL366541A1 (en) 2005-02-07
NO20035146L (no) 2003-11-19
SK15542003A3 (sk) 2004-05-04
HUP0400051A2 (hu) 2004-04-28
CZ20033269A3 (en) 2004-03-17
US20040157876A1 (en) 2004-08-12
KR20030097890A (ko) 2003-12-31
EA009731B1 (ru) 2008-02-28
JP2004530695A (ja) 2004-10-07
CN1511026A (zh) 2004-07-07
HRP20030950A2 (en) 2005-08-31
BR0209834A (pt) 2004-06-15
EP1389091A1 (en) 2004-02-18
MEP6308A (xx) 2010-02-10
IS7020A (is) 2003-11-10
MXPA03010596A (es) 2004-03-09
ZA200308594B (en) 2004-11-04
NO20035146D0 (no) 2003-11-19
YU92103A (sh) 2006-05-25

Similar Documents

Publication Publication Date Title
EA200300776A1 (ru) Производные фенэтаноламина для лечения респираторных заболеваний
CA2481848A1 (en) Active ingredient particles carrying clopidogrel or a salt thereof, their use and method of preparation
IL145429A0 (en) N-cyanomethyl amides, processes for the preparation thereof and pharmaceutical compositions containing the same
CY1110318T1 (el) Παραγωγα φαινοξυοξικου οξεος
EA200100524A1 (ru) Амиды антраниловой кислоты и их применение в качестве лекарственных средств
EA017764B8 (ru) Фармацевтическая композиция, способ ее получения и способ лечения вирусных заболеваний с ее использованием
NO20006282D0 (no) Nye cyklosporiner
TW200505837A (en) Novel compounds
MXPA04003636A (es) Composiciones farmaceuticas que comprenden acido micofenolico o sal de micofenolato.
EA200300334A1 (ru) Новая соль периндоприла и содержащие ее фармацевтические композиции
AU7642001A (en) Novel $G(Y) crystalline form of perindopril tert-butylamine salt, preparation method, and pharmaceutical compositions containing same.
EA200702375A1 (ru) Производные мочевины, способы их получения и применения
DK1373207T3 (da) Nyt amlodipincamsylat og fremgangsmåde til fremstilling heraf
NO20024237L (no) Farmasöytiske formuleringer
IL160171A0 (en) Depsipeptide derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
EA200700703A1 (ru) Гранулярные препараты габоксадола
HUP0303813A3 (en) Arylsulfonamides as antiviral agents, process for preparation of the compounds and pharmaceutical compositions containing them
NO20023551D0 (no) Ibuprofen-inneholdende aktivt middel-preparat
MXPA02012889A (es) Esteres de acidos 4-alcoxi-ciclohexano-1-amino-carboxilicos y procedimiento para su obtencion.
ATE519755T1 (de) Modulatoren des vitamin-d-rezeptors
EA200401289A1 (ru) Новые противоинфекционные соединения, способы их получения и фармацевтические композиции, содержащие эти соединения
HUP0600084A2 (en) Pharmaceutical compositions containing ascorbic acid derivatives, methods of production of the active ingredient
WO2004098577A3 (en) Dosage form containing (s)-pantoprazole as active ingredient
DE60302951D1 (de) Pyroglutaminsäure-salz von Amlodipin
WO2002030874A3 (en) Aliphatic, cyclic amino carboxylic acids as integrin antagonists