EA200501504A1 - Лиганды каннабиноидных рецепторов и их применение - Google Patents

Лиганды каннабиноидных рецепторов и их применение

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Publication number
EA200501504A1
EA200501504A1 EA200501504A EA200501504A EA200501504A1 EA 200501504 A1 EA200501504 A1 EA 200501504A1 EA 200501504 A EA200501504 A EA 200501504A EA 200501504 A EA200501504 A EA 200501504A EA 200501504 A1 EA200501504 A1 EA 200501504A1
Authority
EA
Eurasian Patent Office
Prior art keywords
receptor ligands
cannabinoid receptor
cannabinoid receptors
ligands
cannabinoid
Prior art date
Application number
EA200501504A
Other languages
English (en)
Inventor
Филип Альберт Карпино
Роберт Ли Дау
Original Assignee
Пфайзер Продактс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Продактс, Инк. filed Critical Пфайзер Продактс, Инк.
Publication of EA200501504A1 publication Critical patent/EA200501504A1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Изобретение относится к соединениям формулы (I) и (II), которые действуют в качестве лигандов каннабиноидных рецепторов, и их применению для лечения у животных заболеваний, связанных с вовлечением каннабиноидных рецепторов.
EA200501504A 2003-04-23 2004-04-13 Лиганды каннабиноидных рецепторов и их применение EA200501504A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46490803P 2003-04-23 2003-04-23
PCT/IB2004/001357 WO2004094421A1 (en) 2003-04-23 2004-04-13 Cannabinoid receptor ligands and uses thereof

Publications (1)

Publication Number Publication Date
EA200501504A1 true EA200501504A1 (ru) 2006-04-28

Family

ID=33310977

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200501504A EA200501504A1 (ru) 2003-04-23 2004-04-13 Лиганды каннабиноидных рецепторов и их применение

Country Status (31)

Country Link
US (1) US20040214856A1 (ru)
EP (1) EP1622903B1 (ru)
JP (1) JP2006524225A (ru)
KR (1) KR20060006048A (ru)
CN (1) CN1809566A (ru)
AP (1) AP2005003427A0 (ru)
AR (1) AR044037A1 (ru)
AT (1) ATE409700T1 (ru)
AU (1) AU2004232552A1 (ru)
BR (1) BRPI0409791A (ru)
CA (1) CA2521538A1 (ru)
CL (1) CL2004000827A1 (ru)
CO (1) CO5640084A2 (ru)
DE (1) DE602004016839D1 (ru)
EA (1) EA200501504A1 (ru)
EC (1) ECSP056117A (ru)
ES (1) ES2309517T3 (ru)
GT (1) GT200400076A (ru)
IS (1) IS8054A (ru)
MA (1) MA27766A1 (ru)
MX (1) MXPA05011454A (ru)
NL (1) NL1026027C2 (ru)
NO (1) NO20055516L (ru)
OA (1) OA13047A (ru)
PA (1) PA8600601A1 (ru)
PE (1) PE20050419A1 (ru)
TN (1) TNSN05272A1 (ru)
TW (1) TW200510419A (ru)
UY (1) UY28276A1 (ru)
WO (1) WO2004094421A1 (ru)
ZA (1) ZA200508568B (ru)

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OA13047A (en) 2006-11-10
BRPI0409791A (pt) 2006-05-30
CA2521538A1 (en) 2004-11-04
CN1809566A (zh) 2006-07-26
ATE409700T1 (de) 2008-10-15
CL2004000827A1 (es) 2005-03-04
IS8054A (is) 2005-09-29
CO5640084A2 (es) 2006-05-31
MXPA05011454A (es) 2005-12-12
ECSP056117A (es) 2006-03-01
ZA200508568B (en) 2007-04-25
US20040214856A1 (en) 2004-10-28
ES2309517T3 (es) 2008-12-16
AR044037A1 (es) 2005-08-24
NL1026027A1 (nl) 2004-10-27
KR20060006048A (ko) 2006-01-18
GT200400076A (es) 2004-12-16
NO20055516L (no) 2005-11-22
TW200510419A (en) 2005-03-16
AP2005003427A0 (en) 2005-12-31
DE602004016839D1 (de) 2008-11-13
WO2004094421A1 (en) 2004-11-04
UY28276A1 (es) 2004-11-30
TNSN05272A1 (fr) 2007-07-10
EP1622903B1 (en) 2008-10-01
NL1026027C2 (nl) 2005-07-05
PA8600601A1 (es) 2005-05-24
PE20050419A1 (es) 2005-06-18
JP2006524225A (ja) 2006-10-26
AU2004232552A1 (en) 2004-11-04
EP1622903A1 (en) 2006-02-08
MA27766A1 (fr) 2006-02-01

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