DOP2012000037A - Octasacáridos n-acilos activadores de los receptores de los fgf, su preparación y su aplicación en terapéutica. - Google Patents
Octasacáridos n-acilos activadores de los receptores de los fgf, su preparación y su aplicación en terapéutica.Info
- Publication number
- DOP2012000037A DOP2012000037A DO2012000037A DO2012000037A DOP2012000037A DO P2012000037 A DOP2012000037 A DO P2012000037A DO 2012000037 A DO2012000037 A DO 2012000037A DO 2012000037 A DO2012000037 A DO 2012000037A DO P2012000037 A DOP2012000037 A DO P2012000037A
- Authority
- DO
- Dominican Republic
- Prior art keywords
- activadores
- acilos
- therapeutics
- preparation
- application
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Physical Education & Sports Medicine (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
Abstract
OCTASACARIDOS N-ACILOS ACTIVADORES DE LOS RECEPTORES DE LOS FGF, QUE RESPONDEN A LA FORMULA (I): EN LA QUE R1 REPRESENTA UN GRUPO O-ALQUILO SUSTITUIDO OPCIONALEMENTE CON UNO O VARIOS GRUPOS ARILOS O CICLOALQUILOS, R2 REPRESENTA UN GRUPO OSO3- O HIDROXILO, R3 REPRESENTA UN GRUPO ALQUILO, CICLIALQUILO O ALQUILCICLOALQUILO, Y R4 REPRESENTA UN DISACARIDO DE FORMULA (II), R6 REPRESENTA UN DISACARIDO DE FORMULA (III) Y R8 REPRESENTA UN DISACARIDO DE FORMULA (IV), EN LA QUE R5, R7 Y R9 REPRESENTAN LOS GRUPOS OSO3- O HIDROXILOS: SU PREPARACION Y SU APLICACION EN TERAPEUTICA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0903968A FR2949114B1 (fr) | 2009-08-14 | 2009-08-14 | OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
Publications (1)
Publication Number | Publication Date |
---|---|
DOP2012000037A true DOP2012000037A (es) | 2012-04-15 |
Family
ID=42035764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DO2012000037A DOP2012000037A (es) | 2009-08-14 | 2012-02-08 | Octasacáridos n-acilos activadores de los receptores de los fgf, su preparación y su aplicación en terapéutica. |
Country Status (27)
Country | Link |
---|---|
US (1) | US9012413B2 (es) |
EP (1) | EP2464667A2 (es) |
JP (1) | JP5671536B2 (es) |
KR (1) | KR101718567B1 (es) |
CN (1) | CN102574931B (es) |
AR (1) | AR078094A1 (es) |
AU (1) | AU2010283614B2 (es) |
BR (1) | BR112012007883A2 (es) |
CA (1) | CA2771056C (es) |
CL (1) | CL2012000393A1 (es) |
CO (1) | CO6612193A2 (es) |
DO (1) | DOP2012000037A (es) |
EA (1) | EA020485B1 (es) |
EC (1) | ECSP12011671A (es) |
FR (1) | FR2949114B1 (es) |
IL (1) | IL218068A (es) |
MA (1) | MA33573B1 (es) |
MX (1) | MX2012001947A (es) |
NI (1) | NI201200026A (es) |
NZ (1) | NZ598174A (es) |
PE (1) | PE20120915A1 (es) |
SG (2) | SG10201404221RA (es) |
TN (1) | TN2012000052A1 (es) |
TW (1) | TWI572615B (es) |
UY (1) | UY32843A (es) |
WO (1) | WO2011018588A2 (es) |
ZA (1) | ZA201201028B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2949114B1 (fr) | 2009-08-14 | 2011-08-26 | Sanofi Aventis | OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
FR2949115B1 (fr) * | 2009-08-14 | 2012-11-02 | Sanofi Aventis | OLIGOSACCHARIDES N-SULFATES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
FR2970969B1 (fr) * | 2011-01-27 | 2013-10-18 | Sanofi Aventis | Oligosaccharides 3-o-alkyles activateurs des recepteurs des fgfs, leur preparation et leur application en therapeutique |
WO2012121617A1 (en) * | 2011-03-10 | 2012-09-13 | Industrial Research Limited | Oligosaccharide compounds |
CN104370980B (zh) * | 2014-10-17 | 2017-12-01 | 九芝堂股份有限公司 | 一种抑制内源性因子x酶活性的寡糖类化合物及其药物组合物 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US481816A (en) * | 1892-08-30 | Coin-controlled mechanism | ||
EP0300099A1 (en) * | 1987-07-20 | 1989-01-25 | Akzo N.V. | New pentasaccharides |
EP0333243A3 (en) * | 1988-03-10 | 1989-09-27 | Akzo N.V. | Sulphated k5 antigen and sulphated k5 antigen fragments |
WO1992018546A1 (en) * | 1991-04-17 | 1992-10-29 | Glycomed, Inc. | Sulfated polysaccharides as inhibitors of smooth muscle cell proliferation |
IL102758A (en) | 1991-08-23 | 1997-03-18 | Akzo Nv | Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them |
FR2704226B1 (fr) | 1993-04-22 | 1995-07-21 | Sanofi Elf | 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
NZ264340A (en) | 1993-09-01 | 1995-04-27 | Akzo Nobel Nv | Bisconjugate comprising two saccharides and a spacer, use in pharmaceutical compositions |
FR2749849B1 (fr) * | 1996-06-14 | 1998-09-04 | Sanofi Sa | Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant |
FR2751334B1 (fr) | 1996-07-19 | 1998-10-16 | Sanofi Sa | Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant |
FR2773804B1 (fr) | 1998-01-19 | 2000-02-18 | Sanofi Sa | Polysaccharides de synthese, procede pour leur preparation et compositions pharmaceutiques le contenant |
FR2800074B1 (fr) * | 1999-10-22 | 2001-12-21 | Aventis Pharma Sa | Nouveaux oligosaccharides, leur preparation et les compositions pharmaceutiques les contenant |
US6617316B1 (en) | 1999-10-22 | 2003-09-09 | Aventis Pharma | Oligosaccharides, their preparation and pharmaceutical compositions containing them |
US7582737B2 (en) | 2004-07-20 | 2009-09-01 | Academia Sinica | Orthogonally protected disaccharide building blocks for synthesis of heparin oligosaccharides |
FR2873377B1 (fr) * | 2004-07-23 | 2006-10-13 | Sanofi Synthelabo | Derives d'azasucre, inhibiteurs d'heparanases, leur procede de preparation, les compositions en contenant et leur utilisation |
CA2652205A1 (en) * | 2006-05-25 | 2007-12-06 | Mallik Sundaram | Low molecular weight heparin composition and uses thereof |
FR2949114B1 (fr) | 2009-08-14 | 2011-08-26 | Sanofi Aventis | OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
-
2009
- 2009-08-14 FR FR0903968A patent/FR2949114B1/fr not_active Expired - Fee Related
-
2010
- 2010-08-12 EA EA201270277A patent/EA020485B1/ru not_active IP Right Cessation
- 2010-08-12 CN CN201080046585.0A patent/CN102574931B/zh not_active Expired - Fee Related
- 2010-08-12 EP EP10761049A patent/EP2464667A2/fr not_active Withdrawn
- 2010-08-12 PE PE2012000205A patent/PE20120915A1/es not_active Application Discontinuation
- 2010-08-12 SG SG10201404221RA patent/SG10201404221RA/en unknown
- 2010-08-12 KR KR1020127006510A patent/KR101718567B1/ko active IP Right Grant
- 2010-08-12 WO PCT/FR2010/051703 patent/WO2011018588A2/fr active Application Filing
- 2010-08-12 CA CA2771056A patent/CA2771056C/fr active Active
- 2010-08-12 JP JP2012524265A patent/JP5671536B2/ja not_active Expired - Fee Related
- 2010-08-12 NZ NZ598174A patent/NZ598174A/en not_active IP Right Cessation
- 2010-08-12 BR BR112012007883A patent/BR112012007883A2/pt active Search and Examination
- 2010-08-12 SG SG2012010203A patent/SG178405A1/en unknown
- 2010-08-12 AU AU2010283614A patent/AU2010283614B2/en not_active Ceased
- 2010-08-12 MX MX2012001947A patent/MX2012001947A/es active IP Right Grant
- 2010-08-13 AR ARP100102985A patent/AR078094A1/es unknown
- 2010-08-13 TW TW099127180A patent/TWI572615B/zh not_active IP Right Cessation
- 2010-08-13 UY UY0001032843A patent/UY32843A/es not_active Application Discontinuation
-
2012
- 2012-02-03 TN TNP2012000052A patent/TN2012000052A1/fr unknown
- 2012-02-08 DO DO2012000037A patent/DOP2012000037A/es unknown
- 2012-02-09 US US13/369,675 patent/US9012413B2/en not_active Expired - Fee Related
- 2012-02-12 IL IL218068A patent/IL218068A/en not_active IP Right Cessation
- 2012-02-13 EC ECSP12011671 patent/ECSP12011671A/es unknown
- 2012-02-13 CO CO12024409A patent/CO6612193A2/es not_active Application Discontinuation
- 2012-02-13 NI NI201200026A patent/NI201200026A/es unknown
- 2012-02-13 ZA ZA2012/01028A patent/ZA201201028B/en unknown
- 2012-02-14 CL CL2012000393A patent/CL2012000393A1/es unknown
- 2012-03-08 MA MA34673A patent/MA33573B1/fr unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CL2017003258A1 (es) | Nuevos derivados hidroxiéster, un proceso para su preparación y composiciones farmacéuticas que los contienen | |
ECSP12012011A (es) | Ciertas triazolopiridinas y triazolopirazinas, composiciones de estas y sus métodos de empleo | |
CU24309B1 (es) | Compuestos derivados tienopirimidina y composiciones farmacéuticas que los contienen | |
CR20170118A (es) | Derivados espirodiamina como inhibidores de la aldosterona sintasa | |
CO7170131A2 (es) | Compuestos de heterociclilo | |
CL2013003450A1 (es) | Composicion que contiene oxintomodulina, un polimero de polietilenglicol y 9-fluorenilmetoxicarbonilo o 2-sulfo-9-fluorenilmetoxicarbonilo; metodos de uso. | |
SV2011003800A (es) | Derivados de piridino-piridinonas, su preparacion y su aplicacion en terapeutica | |
CL2011002825A1 (es) | Compuestos derivados de bencimidazol heteroarilo sustituido; composición farmacéutica que los comprende; y su uso en el tratamiento de la hepatitis c. | |
CR20120158A (es) | Compuestos de diòxido de iminotiadiazina como inhibidores de bace, composiciones y su uso. | |
GT201300196A (es) | Moduladores del receptor de glucagón | |
UY34336A (es) | Derivados 5-fluoro pirimidina disustituidos que contienen un grupo sulfoximina | |
ATE496051T1 (de) | Pyrazolotetrahydropyridinderivate als orexinrezeptorantagonisten | |
DOP2012000037A (es) | Octasacáridos n-acilos activadores de los receptores de los fgf, su preparación y su aplicación en terapéutica. | |
BR112013018747A2 (pt) | aditivos para composições líquidas curáveis | |
DOP2013000307A (es) | Antagonistas de trpv4 | |
NI200900042A (es) | Nuevo derivados de dismetina, su procedimiento de preparación y las composiciones farmacéuticas que los contienen. | |
CR20120362A (es) | Ciertas triazolopiridinas y triazolopirazinas, composiciones de estas y sus métodos de empleo | |
BR112015008912A2 (pt) | composições solidificáveis compreendendo volastonita e pedra-pomes e métodos de uso | |
CR20110062A (es) | Nuevos derivados de acilaminobenzamida | |
EA201200602A1 (ru) | Индазолы и пиразолопиридины в качестве антагонистов рецептора ccr1 | |
UA114123C2 (xx) | Водна композиція диклофенаку | |
NI201600016A (es) | Nuevos compuestos isoindolina o isoquinolina, un proceso para su preparación y composiciones farmacéuticas que los continen. | |
FR3003753B1 (fr) | Composition hydro-alcoolique parfumante contenant un ether aliphatique | |
TR201100150A2 (tr) | Suda çözünür dozaj formları | |
AR084310A1 (es) | Polimero y metodos para prepararlo y usarlo |