DK669088D0 - Fremgangsmaade og praeparat til forbedring af erkendelsesfunktionen - Google Patents

Fremgangsmaade og praeparat til forbedring af erkendelsesfunktionen

Info

Publication number
DK669088D0
DK669088D0 DK669088A DK669088A DK669088D0 DK 669088 D0 DK669088 D0 DK 669088D0 DK 669088 A DK669088 A DK 669088A DK 669088 A DK669088 A DK 669088A DK 669088 D0 DK669088 D0 DK 669088D0
Authority
DK
Denmark
Prior art keywords
improving
procedure
preparation
recognition function
cycloserine
Prior art date
Application number
DK669088A
Other languages
English (en)
Other versions
DK669088A (da
DK173589B1 (da
Inventor
Alex A Cordi
Gail E Handelmann
Joseph B Monahan
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of DK669088D0 publication Critical patent/DK669088D0/da
Publication of DK669088A publication Critical patent/DK669088A/da
Application granted granted Critical
Publication of DK173589B1 publication Critical patent/DK173589B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
DK198806690A 1987-12-01 1988-11-30 Anvendelse af D-cycloserin og dets forstadier eller farmaceutisk acceptable salte deraf til fremstilling af præparater til DK173589B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/127,121 US4904681A (en) 1987-12-01 1987-12-01 D-cycloserine and its prodrugs as cognitive enhancers
US12712187 1987-12-01

Publications (3)

Publication Number Publication Date
DK669088D0 true DK669088D0 (da) 1988-11-30
DK669088A DK669088A (da) 1989-06-02
DK173589B1 DK173589B1 (da) 2001-04-02

Family

ID=22428413

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198806690A DK173589B1 (da) 1987-12-01 1988-11-30 Anvendelse af D-cycloserin og dets forstadier eller farmaceutisk acceptable salte deraf til fremstilling af præparater til

Country Status (20)

Country Link
US (1) US4904681A (da)
EP (2) EP0319824B1 (da)
JP (2) JPH0621065B2 (da)
KR (1) KR0134198B1 (da)
AT (1) ATE68698T1 (da)
AU (4) AU622630B2 (da)
CA (1) CA1328617C (da)
DE (1) DE3865817D1 (da)
DK (1) DK173589B1 (da)
ES (1) ES2040314T3 (da)
FI (1) FI885559A0 (da)
GR (1) GR3003571T3 (da)
IE (1) IE61825B1 (da)
IL (1) IL88531A (da)
NO (1) NO885337D0 (da)
NZ (1) NZ227131A (da)
PH (1) PH26467A (da)
PT (1) PT89109B (da)
WO (1) WO1989005144A1 (da)
ZA (1) ZA888981B (da)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5187171A (en) * 1989-01-09 1993-02-16 G. D. Searle & Co. Use of a glycine b partial agonist as an antipsychotic
US5061721A (en) * 1989-03-15 1991-10-29 G. D. Searle & Co. Composition containing d-cycloserine and d-alanine for memory and learning enhancement or treatment of a cognitive or psychotic disorder
US5260324A (en) * 1990-02-06 1993-11-09 G. D. Searle & Company Composition containing D-cycloserine and D-alanine for memory and learning enhancement or treatment of a cognitive or psychotic disorder
US5066665A (en) * 1990-05-21 1991-11-19 Warner-Lambert Co. Substituted isoxazolidin-3-ones and derivatives thereof acting at muscarinic receptors
JPH07505908A (ja) * 1992-09-28 1995-06-29 マックセチーニ、マリア　ルイザ Ｎｍｄａ受容体のアロステリックモジュレーター
US5428069A (en) * 1993-01-11 1995-06-27 The United States Of America As Represented By The Department Of Health & Human Services Treating cognition with, aminocyclopropanecarboxylic derivatives
US5523323A (en) * 1993-09-14 1996-06-04 Maccecchini; Maria-Luisa Use of partial agonists of the NMDA receptor to reduce opiate induced tolerance and dependence
NZ260302A (en) * 1994-04-13 1996-05-28 New Zealand Meat Ind Res Inst Treating bait aversion by including substances which disrupt the associative learning process into bait compositions
WO1996015787A1 (en) * 1994-11-23 1996-05-30 G.D. Searle & Co. Use of amino-isoxazolidone compounds for treatment of memory impairment following traumatic brain injury
WO1996015788A1 (en) * 1994-11-23 1996-05-30 G.D. Searle & Co. Use of amino-isoxazolidone compounds for improvement of implicit memory
US5731348A (en) * 1995-02-15 1998-03-24 Bearsden Bio, Inc. Alkylcarboxy amino acids-modulators of the kainate receptor
US6361957B1 (en) 1999-08-03 2002-03-26 Glytech, Inc. Assay for D-serine transport antagonist and use for treating psychosis
US6355681B2 (en) * 1995-12-07 2002-03-12 Glytech, Inc. Glycine substitutes and precursors for treating a psychosis
EP0871440B1 (en) * 1995-12-07 2006-03-22 Daniel C. Javitt Treatment of negative and cognitive symptoms of schizophrenia with glycine uptake antagonists
FR2742748B1 (fr) * 1995-12-21 1998-01-30 Adir Nouveau derive de 4-imidazolidinone, son procede de preparation et les compositions pharmaceutiques qui le contiennent
KR100396114B1 (ko) * 1996-10-31 2003-11-20 동아제약 주식회사 D-시클로세린의 제조방법
ATE369848T1 (de) 1998-04-14 2007-09-15 Gen Hospital Corp Verwendung von d-serine oder d-alanine zur behandlung von schizophrenie
ES2262322T3 (es) 1998-06-10 2006-11-16 Meiji Seika Kaisha, Ltd. Tratamiento de la degenaracion espinocereberal y comoposiciones utiles para el tratamiento de degeneracion espinocerebelar.
US20040122090A1 (en) * 2001-12-07 2004-06-24 Lipton Stuart A. Methods for treating neuropsychiatric disorders with nmda receptor antagonists
ATE519485T1 (de) * 2001-03-29 2011-08-15 Michael Davis Akute pharmakologische verstärkung einer psychotherapie mit d-cycloserine
US20060252761A1 (en) * 2001-03-29 2006-11-09 Michael Davis Augmentation of extinction via administration of sub-antimicrobial doses of D-cycloserine
CN1527813A (zh) * 2001-04-02 2004-09-08 О 作为治疗剂的抗氧化剂硝基氧和亚硝氮碳基
US7160913B2 (en) * 2002-09-13 2007-01-09 Thomas Jefferson University Methods and kit for treating Parkinson's disease
UA80055C2 (en) * 2003-05-27 2007-08-10 Forest Laboratories Combination of nmda-receptor antagonist and selective inhibitor of serotonin reuptake for a depression and other pscihiatric disorders treatment
CA2534909A1 (en) * 2003-08-08 2005-02-17 The Burnham Institute P16 mediated regulation of nmda receptors
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
EP2243475B1 (en) 2005-04-06 2016-01-13 Adamas Pharmaceuticals, Inc. Combination of memantine and donepezil for treatment of CNS disorders
JP5702288B2 (ja) 2008-09-18 2015-04-15 ノースウエスタン ユニバーシティ Ｎｍｄａレセプターモジュレータ及びその用途
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
US8951968B2 (en) 2009-10-05 2015-02-10 Northwestern University Methods of treating depression and other related diseases
BR112012020142A2 (pt) 2010-02-11 2020-08-18 Northwestern University moduladores do receptor de nmda com estrutura secundária estabilizada e usos dos mesmos.
KR101692275B1 (ko) 2010-02-11 2017-01-04 노오쓰웨스턴 유니버시티 ２차 구조 안정화된 ｎｍｄａ 수용체 조절제 및 그의 용도
WO2014120789A1 (en) 2013-01-29 2014-08-07 Naurex, Inc. Spiro-lactam nmda receptor modulators and uses thereof
CA2899191A1 (en) 2013-01-29 2014-08-07 Naurex, Inc. Spiro-lactam nmda receptor modulators and uses thereof
WO2014120784A1 (en) 2013-01-29 2014-08-07 Naurex, Inc. Spiro-lactam nmda receptor modulators and uses thereof
LT3514158T (lt) 2013-01-29 2023-02-10 Aptinyx Inc. Spirolaktaminiai nmda receptoriaus moduliatoriai ir jų panaudojimas
SG11201505934XA (en) 2013-01-29 2015-09-29 Naurex Inc Spiro-lactam nmda receptor modulators and uses thereof
PE20190174A1 (es) 2016-05-19 2019-02-01 Aptinyx Inc Moduladores del receptor espiro-lactama n-metil-d-aspartato y usos de los mismos
WO2017201285A1 (en) 2016-05-19 2017-11-23 Aptinyx Inc. Spiro-lactam nmda receptor modulators and uses thereof
IL264482B (en) 2016-08-01 2022-09-01 Aptinyx Inc Spiro-lactam nmda modulators and methods of their use
IL286107B1 (en) 2016-08-01 2024-05-01 Aptinyx Inc Spiro-lactam NMDA receptor modulators and their uses
BR112019001921A2 (pt) 2016-08-01 2019-05-14 Aptinyx Inc. moduladores do receptor nmda de espiro-lactama e seus usos
MX2019001319A (es) 2016-08-01 2019-07-04 Aptinyx Inc Moduladores del receptor nmda espiro-lactam y uso de los mismos.
EP3490994B8 (en) 2016-08-01 2024-03-13 Tenacia Biotechnology (Hong Kong) Co., Limited Spiro-lactam and bis-spiro-lactam nmda receptor modulators and uses thereof
EP3427729A1 (en) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid for use in treating epileptic diseases, disorders or conditions
KR20200115611A (ko) 2018-01-31 2020-10-07 앱티닉스 인크. 스피로-락탐 nmda 수용체 조정제 및 그의 용도
US12012413B2 (en) 2019-11-11 2024-06-18 Tenacia Biotechnology (Hong Kong) Co., Limited Methods of treating painful diabetic peripheral neuropathy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3050800C2 (da) * 1979-03-22 1989-06-22 Continental Pharma Inc., Bruessel/Bruxelles, Be

Also Published As

Publication number Publication date
WO1989005144A1 (en) 1989-06-15
PT89109A (pt) 1989-12-29
EP0319824A1 (en) 1989-06-14
PH26467A (en) 1992-07-27
CA1328617C (en) 1994-04-19
IL88531A (en) 1993-02-21
DK669088A (da) 1989-06-02
US4904681A (en) 1990-02-27
AU2813089A (en) 1989-07-05
PT89109B (pt) 1993-07-30
AU1083992A (en) 1992-05-07
JPH05201859A (ja) 1993-08-10
KR890009392A (ko) 1989-08-01
JPH0621065B2 (ja) 1994-03-23
NZ227131A (en) 1991-09-25
ATE68698T1 (de) 1991-11-15
DK173589B1 (da) 2001-04-02
EP0421997A1 (en) 1991-04-17
IE883567L (en) 1989-06-01
JPH01193220A (ja) 1989-08-03
IE61825B1 (en) 1994-11-30
AU622630B2 (en) 1992-04-16
KR0134198B1 (ko) 1998-04-21
DE3865817D1 (da) 1991-11-28
GR3003571T3 (da) 1993-03-16
EP0319824B1 (en) 1991-10-23
FI885559A0 (fi) 1988-11-30
IL88531A0 (en) 1989-06-30
ES2040314T3 (es) 1995-04-01
AU7746794A (en) 1995-01-05
NO885337D0 (no) 1988-11-30
AU2631988A (en) 1989-06-01
ZA888981B (en) 1990-01-31

Similar Documents

Publication Publication Date Title
DK669088D0 (da) Fremgangsmaade og praeparat til forbedring af erkendelsesfunktionen
DE3779053D1 (da)
FI931708A0 (fi) Herbicida substituerade aryl-haloalkylpyrazoler
DE3774896D1 (de) Steilheitsverstaerker.
NO880809D0 (no) Antihyperkloresterolemiske tetrazolforbindelser.
DK0655454T3 (da) Fremgangsmåde til fremstilling af 2,2-difluorketensilylacetaler og alfa,alfa-difluor-beta-silyloxy-1,3-dioxolan-4-propansyreestere
DE3880982D1 (de) Bandspannungsvorrichtung.
ES2042726T3 (es) Beta-alquilmelatoninas.
DE3851470T2 (de) Methoxymethylverbindungen.
DE3850923D1 (de) Operationsverstärkerstufen.
NO885005D0 (no) Vannavstende belegg.
FI881267A0 (fi) Filmer och band.
DE3779675D1 (de) 6-(disubstituiertes amino)carbapenam-verbindungen.
ATE93512T1 (de) Oximino-aether-verbindungen.
DE3878192D1 (de) N-phenyltetrahydrophthalimidverbindungen.
DE68913972T2 (de) Oxazolidin-Verbindung.
IT8019611A0 (it) Procedimento per la stabilizzazione di un composto alogenante.
DK504988A (da) Fremgangsmaade til fremstilling af makrolidforbindelser
DK505888D0 (da) Fremgangsmaade til fremstilling af makrolidforbindelser
NO872282D0 (no) Framgangsmaate for traaling.
KR870001414U (ko) 버섯용 원목폿트(pot)
SE8704332D0 (sv) Hothouse for cultivation
MX9203569A (es) Compuestos benzoheterociclicos.
DK504888A (da) Fremgangsmaade til fremstilling af makrolidforbindelser
ATE81855T1 (de) 5-heterocyclisch substituierte oxazolidinhalogenacetamide.

Legal Events

Date Code Title Description
PBP Patent lapsed

Country of ref document: DK