DK541177A - Fremgangsmaade til fremstilling af derivater af vinca-alkaloider - Google Patents

Fremgangsmaade til fremstilling af derivater af vinca-alkaloider

Info

Publication number: DK541177A
Authority: DK; Denmark
Prior art keywords: vinca alkaloid; alkaloid derivatives; preparing; preparing vinca; derivatives
Prior art date: 1976-12-06

Application number

DK541177A

Other languages

English (en)

Other versions

DK144916B (da

DK144916C (da

Inventor

J C Miller

G E Gutowski

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-12-06

Filing date

1977-12-05

Publication date

1978-06-07

1977-12-05 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1978-06-07 Publication of DK541177A publication Critical patent/DK541177A/da

1982-07-05 Publication of DK144916B publication Critical patent/DK144916B/da

1982-12-06 Application granted granted Critical

1982-12-06 Publication of DK144916C publication Critical patent/DK144916C/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

DK541177A 1976-12-06 1977-12-05 Fremgangsmaade til fremstilling af vlb-3-spiro-5"-oxazolidin-2",4"-dion eller ikke-toxiske syreadditionssalte heraf DK144916C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US74757576		1976-12-06
US05/747,575 US4096148A (en)	1976-12-06	1976-12-06	Oxazolidinedione derivatives of Vinca alkaloids

Publications (3)

Publication Number	Publication Date
DK541177A true DK541177A (da)	1978-06-07
DK144916B DK144916B (da)	1982-07-05
DK144916C DK144916C (da)	1982-12-06

Family

ID=25005690

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK541177A DK144916C (da)	1976-12-06	1977-12-05	Fremgangsmaade til fremstilling af vlb-3-spiro-5"-oxazolidin-2",4"-dion eller ikke-toxiske syreadditionssalte heraf
DK541077A DK145001C (da)	1976-12-06	1977-12-05	Fremgangsmaade til fremstilling af derivater af vinca-alkaloider

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK541077A DK145001C (da)	1976-12-06	1977-12-05	Fremgangsmaade til fremstilling af derivater af vinca-alkaloider

Country Status (31)

Country	Link
US (1)	US4096148A (da)
JP (1)	JPS5371100A (da)
AR (1)	AR218467A1 (da)
AT (2)	AT353987B (da)
AU (1)	AU513936B2 (da)
BE (1)	BE861417A (da)
BG (1)	BG33436A3 (da)
CA (2)	CA1082180A (da)
CH (2)	CH632516A5 (da)
CS (2)	CS195343B2 (da)
DD (2)	DD134227A5 (da)
DE (1)	DE2753791A1 (da)
DK (2)	DK144916C (da)
ES (2)	ES464764A1 (da)
FR (1)	FR2372839A1 (da)
GB (1)	GB1590649A (da)
GR (2)	GR67243B (da)
HK (1)	HK57281A (da)
HU (2)	HU180725B (da)
IE (1)	IE46105B1 (da)
IL (1)	IL53506A (da)
MX (1)	MX4326E (da)
MY (1)	MY8200176A (da)
NL (1)	NL7713336A (da)
NZ (1)	NZ185818A (da)
PL (2)	PL106522B1 (da)
PT (2)	PT67342B (da)
RO (2)	RO75391A (da)
SE (2)	SE435930B (da)
SU (2)	SU843753A3 (da)
ZA (1)	ZA777237B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU181874B (en) *	1977-08-08	1983-11-28	Lilly Co Eli	Process for preparing amides of deacetyl-leurosine and deacetyl-leuroformine
US4357334A (en) *	1980-03-20	1982-11-02	Eli Lilly And Company	Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
US4362664A (en) *	1980-12-29	1982-12-07	Eli Lilly And Company	Vinblastine oxazolidinedione disulfides and related compounds
GR81790B (da) *	1983-04-29	1984-12-12	Omnichem Sa
HUT76925A (hu) *	1995-04-04	1998-01-28	MTA Enzimológiai Intézet	Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények
CA2385528C (en)	1999-10-01	2013-12-10	Immunogen, Inc.	Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL125835C (da) *	1960-05-24
HU165986B (da) *	1973-02-16	1974-12-28
AR204004A1 (es) *	1973-04-02	1975-11-12	Lilly Co Eli	Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
US4012390A (en) *	1974-10-16	1977-03-15	Eli Lilly And Company	Vinblastinoic acid

1976
- 1976-12-06 US US05/747,575 patent/US4096148A/en not_active Expired - Lifetime
1977
- 1977-11-30 CS CS777939A patent/CS195343B2/cs unknown
- 1977-11-30 RO RO7792261A patent/RO75391A/ro unknown
- 1977-11-30 GB GB49906/77A patent/GB1590649A/en not_active Expired
- 1977-11-30 CA CA292,101A patent/CA1082180A/en not_active Expired
- 1977-11-30 NZ NZ185818A patent/NZ185818A/xx unknown
- 1977-11-30 SE SE7713587A patent/SE435930B/sv not_active IP Right Cessation
- 1977-11-30 GR GR54897A patent/GR67243B/el unknown
- 1977-11-30 RO RO7792262A patent/RO74137A/ro unknown
- 1977-11-30 PT PT67342A patent/PT67342B/pt unknown
- 1977-11-30 CS CS777940A patent/CS195344B2/cs unknown
- 1977-11-30 CA CA292,072A patent/CA1103664A/en not_active Expired
- 1977-11-30 SE SE7713586A patent/SE436036B/sv not_active IP Right Cessation
- 1977-11-30 PT PT67343A patent/PT67343B/pt unknown
- 1977-11-30 GR GR54898A patent/GR67244B/el unknown
- 1977-12-01 IL IL53506A patent/IL53506A/xx unknown
- 1977-12-01 NL NL7713336A patent/NL7713336A/xx not_active Application Discontinuation
- 1977-12-02 BG BG7737936A patent/BG33436A3/xx unknown
- 1977-12-02 FR FR7736437A patent/FR2372839A1/fr active Granted
- 1977-12-02 JP JP14561377A patent/JPS5371100A/ja active Granted
- 1977-12-02 BE BE1008557A patent/BE861417A/xx not_active IP Right Cessation
- 1977-12-02 DE DE19772753791 patent/DE2753791A1/de active Granted
- 1977-12-05 PL PL1977202660A patent/PL106522B1/pl unknown
- 1977-12-05 CH CH1486277A patent/CH632516A5/de not_active IP Right Cessation
- 1977-12-05 HU HU77EI7723A patent/HU180725B/hu not_active IP Right Cessation
- 1977-12-05 DK DK541177A patent/DK144916C/da not_active IP Right Cessation
- 1977-12-05 SU SU772549952A patent/SU843753A3/ru active
- 1977-12-05 ES ES464764A patent/ES464764A1/es not_active Expired
- 1977-12-05 AT AT868877A patent/AT353987B/de not_active IP Right Cessation
- 1977-12-05 AT AT868777A patent/AT361638B/de not_active IP Right Cessation
- 1977-12-05 SU SU772549000A patent/SU865127A3/ru active
- 1977-12-05 IE IE2469/77A patent/IE46105B1/en unknown
- 1977-12-05 ZA ZA00777237A patent/ZA777237B/xx unknown
- 1977-12-05 DK DK541077A patent/DK145001C/da not_active IP Right Cessation
- 1977-12-05 MX MX776608U patent/MX4326E/es unknown
- 1977-12-05 CH CH1486177A patent/CH634076A5/de not_active IP Right Cessation
- 1977-12-05 PL PL1977202659A patent/PL110671B1/pl unknown
- 1977-12-05 HU HU77EI771A patent/HU180724B/hu not_active IP Right Cessation
- 1977-12-05 AU AU31230/77A patent/AU513936B2/en not_active Expired
- 1977-12-05 ES ES464765A patent/ES464765A1/es not_active Expired
- 1977-12-06 DD DD77202423A patent/DD134227A5/xx unknown
- 1977-12-06 DD DD77202424A patent/DD134228A5/xx unknown
- 1977-12-06 AR AR270267A patent/AR218467A1/es active
1981
- 1981-11-19 HK HK572/81A patent/HK57281A/xx unknown
1982
- 1982-12-30 MY MY176/82A patent/MY8200176A/xx unknown

Also Published As

Publication number	Publication date
MX4326E (es)	1982-03-24
SU843753A3 (ru)	1981-06-30
GB1590649A (en)	1981-06-03
DE2753791C2 (da)	1990-08-02
ES464764A1 (es)	1979-01-01
RO75391A (ro)	1980-11-30
SE436036B (sv)	1984-11-05
IL53506A (en)	1981-09-13
US4096148A (en)	1978-06-20
SE7713587L (sv)	1978-06-07
GR67243B (da)	1981-06-25
IE46105B1 (en)	1983-02-23
ES464765A1 (es)	1979-01-01
BG33436A3 (en)	1983-02-15
ATA868777A (de)	1980-08-15
GR67244B (da)	1981-06-25
HU180725B (en)	1983-04-29
RO74137A (ro)	1981-08-30
DK145001C (da)	1982-12-27
HU180724B (en)	1983-04-29
AT353987B (de)	1979-12-10
SE435930B (sv)	1984-10-29
CH632516A5 (de)	1982-10-15
PT67343B (en)	1979-04-26
DK541077A (da)	1978-06-07
SU865127A3 (ru)	1981-09-15
AR218467A1 (es)	1980-06-13
IE46105L (en)	1978-06-06
PL202659A1 (pl)	1978-12-04
CA1082180A (en)	1980-07-22
BE861417A (fr)	1978-06-02
AU3123077A (en)	1979-06-14
IL53506A0 (en)	1978-03-10
DE2753791A1 (de)	1978-06-08
PL106522B1 (pl)	1979-12-31
PT67342A (en)	1977-12-01
CA1103664A (en)	1981-06-23
AU513936B2 (en)	1981-01-15
JPS625160B2 (da)	1987-02-03
PL110671B1 (en)	1980-07-31
FR2372839A1 (fr)	1978-06-30
NZ185818A (en)	1979-12-11
NL7713336A (nl)	1978-06-08
HK57281A (en)	1981-11-27
DD134227A5 (de)	1979-02-14
CS195344B2 (en)	1980-01-31
FR2372839B1 (da)	1981-11-06
SE7713586L (sv)	1978-06-07
AT361638B (de)	1981-03-25
CH634076A5 (de)	1983-01-14
DK145001B (da)	1982-07-26
ATA868877A (de)	1979-05-15
DK144916B (da)	1982-07-05
DD134228A5 (de)	1979-02-14
JPS5371100A (en)	1978-06-24
CS195343B2 (en)	1980-01-31
PL202660A1 (pl)	1978-08-28
DK144916C (da)	1982-12-06
ZA777237B (en)	1979-07-25
PT67343A (en)	1977-12-01
MY8200176A (en)	1982-12-31
PT67342B (en)	1979-04-26

Legal Events

Date	Code	Title	Description
1990-08-20	PBP	Patent lapsed

Publication	Publication Date	Title
DK286777A (da)	1977-12-30	Fremgangsmade til fremstilling af penicillansyrederivater
DK155084C (da)	1989-06-19	Fremgangsmaade til fremstilling af meta-aryloxy-benzaldehyder
DK152765C (da)	1988-10-10	Fremgangsmaade til fremstilling af d-(-)-n-carbamylphenylglycin
DK387177A (da)	1978-03-02	Fremgangsmaade til fremstilling af derivater af perhydro-aza-heterocycler
DK149446C (da)	1986-11-17	Fremgangsmaade til fremstilling af acylcyanider
PL215008A1 (pl)	1979-12-17	Sposob wytwarzania pochodnych piranonu-3
PL197372A1 (pl)	1979-06-18	Sposob wytwarzania pochodnych kanamycyny
DK584777A (da)	1978-07-01	Fremgangsmaade til fremstilling af sterolinforbindelser
DK147436C (da)	1985-03-11	Fremgangsmaade til fremstilling af acylcyanider
PL200583A1 (pl)	1979-06-04	Sposob wytwarzania nowych pochodnych benzopiranu
DK232080A (da)	1980-12-01	Fremgangsmaade til fremstilling af hydroxyaminoeburnanderivater
PL198878A1 (pl)	1978-04-10	Sposob wytwarzania pochodnych 2-chlorosulfinyloazetydynonu
PL200605A1 (pl)	1979-02-12	Sposob wytwarzania nowych pochodnych metioninoenkefaliny
DK541077A (da)	1978-06-07	Fremgangsmaade til fremstilling af derivater af vinca-alkaloider
DK300781A (da)	1981-07-07	Fremgangsmaade til fremstilling af halogenfenylpyridyllylamin-derivater
SE442707B (sv)	1986-01-27	Forfarande for utvinning av intravenost fordragbart gammaglobulin
DK551977A (da)	1978-06-11	Fremgangsmaade til fremstilling af naphthyridinderivater
DK149447C (da)	1986-11-17	Fremgangsmaade til fremstilling af acylcyanider
DK140172C (da)	1979-11-26	Fremgangsmaade til fremstilling af 5-androsten-17-on-derivater
DK235477A (da)	1977-11-29	Fremgangsmade til fremstilling af uracilderivater
DK208677A (da)	1977-11-14	Fremgangsmade til fremstilling af maphthylforbindelser
PL201161A1 (pl)	1979-01-29	Sposob wytwarzania nowych pochodnych 9-chloroprednisolonu
DK22077A (da)	1977-07-22	Fremgangsmade til fremstilling af penicillin- og cephalosporinderivater
DK588677A (da)	1978-07-01	Fremgangsmaade til fremstilling af azopigmenter
PL197646A1 (pl)	1978-01-02	Sposob wytwarzania pochodnych 1-karbamylouracylu