DK468876A - Mellemprodukt til anvendelse ved fremstilling af 3,5-disubstituerede phenylethanolaminforbindelser eller syreadditionssalte heraf - Google Patents

Mellemprodukt til anvendelse ved fremstilling af 3,5-disubstituerede phenylethanolaminforbindelser eller syreadditionssalte heraf

Info

Publication number
DK468876A
DK468876A DK468876A DK468876A DK468876A DK 468876 A DK468876 A DK 468876A DK 468876 A DK468876 A DK 468876A DK 468876 A DK468876 A DK 468876A DK 468876 A DK468876 A DK 468876A
Authority
DK
Denmark
Prior art keywords
disubstituted
preparation
additional salts
acid additional
intermediate use
Prior art date
Application number
DK468876A
Other languages
English (en)
Inventor
K I L Wetterlin
L A Svensson
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Publication of DK468876A publication Critical patent/DK468876A/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/48Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation involving decarboxylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK468876A 1966-10-19 1976-10-18 Mellemprodukt til anvendelse ved fremstilling af 3,5-disubstituerede phenylethanolaminforbindelser eller syreadditionssalte heraf DK468876A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE14182/66A SE335359B (da) 1966-10-19 1966-10-19

Publications (1)

Publication Number Publication Date
DK468876A true DK468876A (da) 1976-10-18

Family

ID=20298669

Family Applications (2)

Application Number Title Priority Date Filing Date
DK518567AA DK128491B (da) 1966-10-19 1967-10-18 Analogifremgangsmåde til fremstilling af en eventuelt esterificeret 1-(3',5'-dihydroxyphenyl)-2-(t-butylamino)- eller -2-(cyclobutylamino)-ethanol eller syreadditionssalte heraf eller de tilsvarende optisk aktive forbindelser.
DK468876A DK468876A (da) 1966-10-19 1976-10-18 Mellemprodukt til anvendelse ved fremstilling af 3,5-disubstituerede phenylethanolaminforbindelser eller syreadditionssalte heraf

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK518567AA DK128491B (da) 1966-10-19 1967-10-18 Analogifremgangsmåde til fremstilling af en eventuelt esterificeret 1-(3',5'-dihydroxyphenyl)-2-(t-butylamino)- eller -2-(cyclobutylamino)-ethanol eller syreadditionssalte heraf eller de tilsvarende optisk aktive forbindelser.

Country Status (13)

Country Link
AT (4) AT287678B (da)
BE (1) BE704932A (da)
CH (1) CH510625A (da)
DE (2) DE1643296C3 (da)
DK (2) DK128491B (da)
ES (5) ES346131A1 (da)
FI (1) FI50786C (da)
FR (1) FR8011M (da)
GB (1) GB1199630A (da)
IT (1) IT8048168A0 (da)
NL (2) NL151693B (da)
NO (1) NO120686B (da)
SE (1) SE335359B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4138581A (en) 1969-04-01 1979-02-06 Sterling Drugs Inc. 3(Hydroxy or hydroxymethyl)-4(hydroxy)-α-(aminomethyl)benzyl alcohols
EP0046144B1 (en) * 1980-07-09 1984-04-11 Aktiebolaget Draco Therapeutically active derivatives of phenylethanol amines
ATE7689T1 (de) 1980-07-09 1984-06-15 Aktiebolaget Draco 1-(dihydroxyphenyl)-2-amino-aethanol-derivate, verfahren und mittel zu ihrer herstellung sowie diese derivate enthaltende mittel.
US4853381A (en) * 1984-04-17 1989-08-01 Glaxo Group Limited Ethanolamine compounds
US4581225A (en) * 1984-04-25 1986-04-08 Eli Lilly And Company Sustained release intranasal formulation and method of use thereof
EP0213108A3 (de) * 1985-06-26 1987-07-15 Kurt Dr. Burghart Pharmazeutische Zubereitung mit einem Antihypotonikum als wirksames Mittel
WO2013081565A1 (en) 2011-11-21 2013-06-06 Mahmut Bilgic Pharmaceutical compositions comprising roflumilast and terbutaline
WO2014108449A1 (en) 2013-01-08 2014-07-17 Atrogi Ab A screening method, a kit, a method of treatment and a compound for use in a method of treatment
WO2018182546A1 (en) 2017-03-27 2018-10-04 İlko Ilaç Sanayi Ve Ticaret Anonim Şirketi Stabilized pharmaceutical syrup composition comprising terbutaline sulphate and ambroxol hydrochloride
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
CN110057932B (zh) * 2019-04-22 2022-03-15 上海旭东海普药业有限公司 高效液相色谱分析硫酸特布他林有关物质的方法
CN111440078A (zh) * 2020-04-26 2020-07-24 梯尔希(南京)药物研发有限公司 特布他林衍生物的制备方法
CN113264839B (zh) * 2021-04-27 2022-08-30 苏州弘森药业股份有限公司 一种使用手性辅基制备左旋特布他林的方法
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses

Also Published As

Publication number Publication date
ES361431A1 (es) 1970-11-01
NL7513854A (nl) 1976-03-31
ES361432A1 (es) 1970-11-01
AT286964B (de) 1971-01-11
AT287679B (de) 1971-02-10
IT8048168A0 (it) 1980-03-14
FI50786B (da) 1976-03-31
GB1199630A (en) 1970-07-22
DE1643296C3 (de) 1974-06-12
AT287678B (de) 1971-02-10
DE1643296B2 (de) 1973-10-25
DE1793759B2 (de) 1978-05-11
FI50786C (fi) 1976-07-12
FR8011M (da) 1970-07-27
ES361429A1 (es) 1970-11-01
DE1793759C3 (de) 1979-01-11
NL6714191A (da) 1968-04-22
AT288356B (de) 1971-03-10
NL151693B (nl) 1976-12-15
ES361433A1 (es) 1970-11-01
ES346131A1 (es) 1969-05-16
DE1793759A1 (de) 1973-08-16
DE1643296A1 (de) 1971-09-30
BE704932A (da) 1968-02-15
SE335359B (da) 1971-05-24
NO120686B (da) 1970-11-23
CH510625A (de) 1971-07-31
DK128491B (da) 1974-05-13

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