DK467388D0 - Quinolon- og naphthyridinderivater, antibakterielle midler indeholdende disse og fremgangsmaader til fremstilling deraf - Google Patents

Quinolon- og naphthyridinderivater, antibakterielle midler indeholdende disse og fremgangsmaader til fremstilling deraf

Info

Publication number
DK467388D0
DK467388D0 DK467388A DK467388A DK467388D0 DK 467388 D0 DK467388 D0 DK 467388D0 DK 467388 A DK467388 A DK 467388A DK 467388 A DK467388 A DK 467388A DK 467388 D0 DK467388 D0 DK 467388D0
Authority
DK
Denmark
Prior art keywords
quinolon
procedures
preparing
antibacterial agents
agents containing
Prior art date
Application number
DK467388A
Other languages
English (en)
Other versions
DK172152B1 (da
DK467388A (da
Inventor
Joseph Peter Sanchez
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DK467388D0 publication Critical patent/DK467388D0/da
Publication of DK467388A publication Critical patent/DK467388A/da
Application granted granted Critical
Publication of DK172152B1 publication Critical patent/DK172152B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK467388A 1987-08-21 1988-08-19 Quinolon- og naphthyridinderivater DK172152B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8795087A 1987-08-21 1987-08-21
US8795087 1987-08-21
US07/220,177 US4851418A (en) 1987-08-21 1988-07-20 Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent
US22017788 1988-07-20

Publications (3)

Publication Number Publication Date
DK467388D0 true DK467388D0 (da) 1988-08-19
DK467388A DK467388A (da) 1989-02-22
DK172152B1 DK172152B1 (da) 1997-12-01

Family

ID=26777552

Family Applications (1)

Application Number Title Priority Date Filing Date
DK467388A DK172152B1 (da) 1987-08-21 1988-08-19 Quinolon- og naphthyridinderivater

Country Status (16)

Country Link
US (1) US4851418A (da)
EP (1) EP0304087B1 (da)
JP (1) JP2679818B2 (da)
KR (1) KR0120389B1 (da)
AU (1) AU608881B2 (da)
CA (1) CA1339216C (da)
DE (1) DE3888754T2 (da)
DK (1) DK172152B1 (da)
ES (1) ES2063011T3 (da)
FI (1) FI90237C (da)
HK (1) HK1000802A1 (da)
IE (1) IE62787B1 (da)
NO (1) NO171979C (da)
NZ (1) NZ225870A (da)
PH (1) PH25460A (da)
PT (1) PT88289B (da)

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US4780468A (en) * 1987-08-07 1988-10-25 Warner-Lambert Company 8-trifluoromethyl quinolones as antibacterial agents
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CA1340285C (en) * 1988-05-19 1998-12-22 Hiroyuki Nagano Novel quinolonecarboxylic acid derivatives having at 7-position a piperidin-1-yl substituent
JP2844079B2 (ja) * 1988-05-23 1999-01-06 塩野義製薬株式会社 ピリドンカルボン酸系抗菌剤
FI95130C (fi) * 1988-07-20 1995-12-27 Sankyo Co Menetelmä lääkeaineena käyttökelpoisten 4-oksokinoliini-3-karboksyylihapon johdannaisten valmistamiseksi
US5057520A (en) * 1989-03-24 1991-10-15 Abbott Laboratories 7-(peptidylpyrolidinyl)naphthyridine antibacterial compounds
US5057523A (en) * 1988-09-22 1991-10-15 Abbott Laboratories Dipeptide quinolone derivatives
IE76284B1 (en) * 1988-09-22 1997-10-08 Abbott Lab Amino acid quinoline and naphthyridine derivatives
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EP0366189A3 (en) * 1988-10-24 1992-01-02 Norwich Eaton Pharmaceuticals, Inc. Novel antimicrobial lactam-quinolones
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FR2676445B1 (fr) * 1991-05-16 1995-02-03 Esteve Labor Dr Derives de pyridone amino acide azetidinyl substitues, leur preparation et leur application en tant que medicaments.
ES2151488T3 (es) * 1991-05-28 2001-01-01 Daiichi Seiyaku Co Derivado de acido piridonacarboxilico.
US5177217A (en) * 1992-04-27 1993-01-05 Warner-Lambert Company Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines
FR2692577B1 (fr) * 1992-05-26 1996-02-02 Bouchara Sa Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant.
US5290794A (en) * 1992-10-27 1994-03-01 Warner Lambert Co. Soluble calcium lactate antibacterial complexes as non-irritating parenteral forms
WO1994025464A1 (en) * 1993-04-24 1994-11-10 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and process for preparing the same
KR950018003A (ko) * 1993-12-09 1995-07-22 스미스클라인 비참 피엘씨 신규한 퀴놀론 유도체 및 그의 제조 방법
RU2140919C1 (ru) * 1994-07-18 1999-11-10 Убе Индастриз Лтд. Производные 8-трифторметилхинолинкарбоновой кислоты, фармацевтическая композиция и способ ингибирования вируса иммунодефицита
US5602254A (en) * 1995-05-26 1997-02-11 Warner-Lambert Company Method for making quinoline carboxylic acids or naphthyridine carboxylic acids in free base form
ES2178701T3 (es) * 1995-06-15 2003-01-01 Pfizer Procedimiento para preparar derivados del acido azabiciclo naftriridina carboxilico que comprenden un dipeptido.
JP4057088B2 (ja) * 1996-04-22 2008-03-05 株式会社カネカ ピロリジン誘導体の製造方法
US6136823A (en) * 1996-11-28 2000-10-24 Wakunaga Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivatives or salts thereof and drugs containing the same as the active ingredient
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US7098219B2 (en) 2000-08-01 2006-08-29 Wockhart Limited Inhibitors of cellular efflux pumps of microbes
SE0003795D0 (sv) 2000-10-20 2000-10-20 Astrazeneca Ab Pharmaceutically useful compounds
US6964966B2 (en) 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6878713B2 (en) 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
WO2003099815A1 (en) 2002-05-28 2003-12-04 Wockhardt Limited Crystalline fluoroquinolone arginine salt form
KR20120030558A (ko) 2003-09-04 2012-03-28 욱크하트 리미티드 벤조퀴놀리진-2-카복실산 아르기닌 염 사수화물
WO2005035493A1 (ja) * 2003-10-08 2005-04-21 Teijin Pharma Limited アミノピロリジン誘導体の製造方法および中間体化合物
KR100939347B1 (ko) 2005-07-20 2010-01-29 (주)카이로드 광학적으로 순수한 (ｓ)-3-히드록시 피롤리딘의 제조방법
CN101239937B (zh) * 2007-02-07 2010-05-19 上海雅本化学有限公司 一种光学活性r-(-)-1-苄氧羰基-3-氨基吡咯烷及其盐酸盐的制备方法
AU2008276512A1 (en) * 2007-07-17 2009-01-22 Amgen Inc. Thiadiazole modulators of PKB
US7902227B2 (en) * 2007-07-27 2011-03-08 Janssen Pharmaceutica Nv. C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents
CN101983187A (zh) * 2008-04-02 2011-03-02 株式会社钟化 (s)-3-(1-氰基-1，1-二苯基甲基)吡咯烷的制备方法
US8445700B2 (en) 2008-11-24 2013-05-21 Council Of Scientific & Industrial Research Process for the preparation of optically active N-benzyl-3 hydroxypyrrolidines
CN114989165A (zh) * 2022-05-30 2022-09-02 青岛大学附属医院 一种抗持留菌和生物膜菌的化合物或组合物及其用途
EP4382529A1 (en) 2022-12-07 2024-06-12 Bayer Consumer Care AG A process for preparing pure (3s)-pyrrolidin-3-ol and pure (3s)-pyrrolidin-3-ol hydrochloride

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Also Published As

Publication number Publication date
FI883807A (fi) 1989-02-22
PT88289B (pt) 1995-03-31
DK172152B1 (da) 1997-12-01
FI90237C (fi) 1994-01-10
NO883722L (no) 1989-02-22
DE3888754D1 (de) 1994-05-05
NO171979B (no) 1993-02-15
JPH01125371A (ja) 1989-05-17
KR890003704A (ko) 1989-04-17
PH25460A (en) 1991-07-01
DE3888754T2 (de) 1994-07-14
PT88289A (pt) 1989-09-14
IE62787B1 (en) 1995-02-22
EP0304087A2 (en) 1989-02-22
KR0120389B1 (ko) 1997-11-04
HK1000802A1 (en) 1998-05-01
NO883722D0 (no) 1988-08-19
ES2063011T3 (es) 1995-01-01
EP0304087A3 (en) 1989-10-25
CA1339216C (en) 1997-08-05
NZ225870A (en) 1990-12-21
FI883807A0 (fi) 1988-08-17
US4851418A (en) 1989-07-25
EP0304087B1 (en) 1994-03-30
NO171979C (no) 1993-05-26
DK467388A (da) 1989-02-22
AU2062988A (en) 1989-02-23
AU608881B2 (en) 1991-04-18
JP2679818B2 (ja) 1997-11-19
IE882363L (en) 1989-02-21
FI90237B (fi) 1993-09-30

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B1 Patent granted (law 1993)
PBP Patent lapsed

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