SE0003795D0 - Pharmaceutically useful compounds - Google Patents

Pharmaceutically useful compounds

Info

Publication number
SE0003795D0
SE0003795D0 SE0003795A SE0003795A SE0003795D0 SE 0003795 D0 SE0003795 D0 SE 0003795D0 SE 0003795 A SE0003795 A SE 0003795A SE 0003795 A SE0003795 A SE 0003795A SE 0003795 D0 SE0003795 D0 SE 0003795D0
Authority
SE
Sweden
Prior art keywords
sup
pharmaceutically useful
useful compounds
arrhythmias
prophylaxis
Prior art date
Application number
SE0003795A
Other languages
English (en)
Inventor
Magnus Bjoersne
Kurt-Juergen Hoffmann
Fritiof Ponten
Gert Strandlund
Peder Svensson
Michael Wilstermann
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0003795A priority Critical patent/SE0003795D0/sv
Publication of SE0003795D0 publication Critical patent/SE0003795D0/sv
Priority to PCT/SE2001/002294 priority patent/WO2002032902A1/en
Priority to AU2001296173A priority patent/AU2001296173A1/en
Priority to EP01977023A priority patent/EP1328526A1/en
Priority to US10/399,663 priority patent/US7012074B2/en
Priority to JP2002536284A priority patent/JP2004511559A/ja

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
SE0003795A 2000-10-20 2000-10-20 Pharmaceutically useful compounds SE0003795D0 (sv)

Priority Applications (6)

Application Number Priority Date Filing Date Title
SE0003795A SE0003795D0 (sv) 2000-10-20 2000-10-20 Pharmaceutically useful compounds
PCT/SE2001/002294 WO2002032902A1 (en) 2000-10-20 2001-10-18 3,8-diazabicyclo[3.2.1]octanes and their use in the treatment of cardiac arrhythmias
AU2001296173A AU2001296173A1 (en) 2000-10-20 2001-10-18 3,8-diazabicyclo(3.2.1)octanes and their use in the treatment of cardiac arrhythmias
EP01977023A EP1328526A1 (en) 2000-10-20 2001-10-18 3,8-diazabicyclo[3.2.1]octanes and their use in the treatment of cardiac arrhythmias
US10/399,663 US7012074B2 (en) 2000-10-20 2001-10-18 3,8-Diazabicyclo[3.2.1]octanes and their use in the treatment of cardiac arrhythmias
JP2002536284A JP2004511559A (ja) 2000-10-20 2001-10-18 3,8−ジアザビシクロ[3.2.1]オクタン及び心不整脈の治療におけるその使用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0003795A SE0003795D0 (sv) 2000-10-20 2000-10-20 Pharmaceutically useful compounds

Publications (1)

Publication Number Publication Date
SE0003795D0 true SE0003795D0 (sv) 2000-10-20

Family

ID=20281488

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0003795A SE0003795D0 (sv) 2000-10-20 2000-10-20 Pharmaceutically useful compounds

Country Status (6)

Country Link
US (1) US7012074B2 (sv)
EP (1) EP1328526A1 (sv)
JP (1) JP2004511559A (sv)
AU (1) AU2001296173A1 (sv)
SE (1) SE0003795D0 (sv)
WO (1) WO2002032902A1 (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ530705A (en) * 2001-07-19 2005-08-26 Cv Therapeutics Inc Substituted piperazine compounds and their use as fatty acid oxidation inhibitors
JP2006510670A (ja) * 2002-12-05 2006-03-30 シーブイ・セラピューティクス・インコーポレイテッド 置換ヘテロ環化合物
EP1578737B1 (en) * 2003-01-03 2009-09-16 Cv Therapeutics, Inc. Substituted heterocyclic compounds
JP2006515891A (ja) * 2003-01-17 2006-06-08 シーブイ・セラピューティクス・インコーポレイテッド 循環器疾患の処置に有効な置換ヘテロ環化合物
CA2530376A1 (en) * 2003-06-23 2005-01-06 Cv Therapeutics, Inc. Urea derivatives of piperazines and piperidines as fatty acid oxidation inhibitors
US8673920B2 (en) * 2009-05-06 2014-03-18 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
CN107383025B (zh) * 2017-06-30 2019-04-26 吉林凯莱英医药化学有限公司 桥环化合物的制备方法
CN111892599B (zh) * 2020-08-14 2023-01-13 黄芳 一种2,5-二氮杂双环[2.2.2]辛烷-2-羧酸叔丁酯的合成方法

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3281421A (en) 1966-10-25 Pharmacologically active j,b-diaza- bicyclo-[j,z,l]-octanes
DE1445993A1 (de) 1961-06-26 1969-06-12 Lepetit S P A Gruppo Perr La R 3,8-Diazabicyclo-(3,2,1)-octane und Verfahren zu ihrer Herstellung
GB949088A (en) 1961-06-26 1964-02-12 Lepetit Spa Diazabicyclo-octane derivatives
US3328396A (en) 1961-11-09 1967-06-27 Sterling Drug Inc 3, 8-di-substituted-3, 8-diazabicyclo [3.2.1] octanes
GB1180060A (en) 1967-12-11 1970-02-04 Lepetit Spa New Diazabicyclo-Octane Derivative
CS149800B1 (sv) 1970-07-30 1973-08-23
DE2428792A1 (de) 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
DE3112055A1 (de) 1981-03-27 1982-10-07 Basf Ag, 6700 Ludwigshafen Bispidinderivate, ihre herstellung und diese enthaltende arzneimittel
FR2531709A1 (fr) 1982-08-13 1984-02-17 Sanofi Sa Diazabicyclooctanes, procede pour leur preparation et compositions pharmaceutiques les renfermant
DE3234697A1 (de) 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
FR2552762B1 (fr) 1983-09-30 1986-07-25 Delalande Sa Nouveaux amides piperaziniques et homopiperaziniques derives de l'acide 3,4-dioxymethylene cinnamique, leur procede de preparation et leur application en therapeutique
AT380346B (de) 1984-03-30 1986-05-12 Siemens Ag Oesterreich Blindenschrift-ausgabegeraet
US4571396A (en) 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
DE3601567A1 (de) 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate
DE3721745A1 (de) 1986-07-04 1988-01-14 Lentia Gmbh Bicyclisch substituierte chinoloncarbonsaeurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
EP0251308B1 (de) 1986-07-04 1990-11-22 Chemie Linz Gesellschaft m.b.H. 4-Chinolon-3-carbonsäurederivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
NZ222047A (en) 1986-10-08 1991-01-29 Bristol Myers Co Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents
ZA877471B (en) 1986-10-08 1988-04-05 Bristol-Myers Company 1-tertiary-alkyl-substituted naphthyridine-and quinoline-carboxylic acid antibacterial agents
DE3702393A1 (de) 1987-01-28 1988-08-11 Bayer Ag 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo- 3-chinolincarbonsaeuren, verfahren zu ihrer herstellung und diese enthaltende antibakterielle mittel
US4780468A (en) 1987-08-07 1988-10-25 Warner-Lambert Company 8-trifluoromethyl quinolones as antibacterial agents
US4851418A (en) 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent
PT88381B (pt) 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
DE3732094A1 (de) 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
CA2012681A1 (en) 1989-03-31 1990-09-30 Masayasu Okuhira Quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same
US5140033A (en) 1989-04-03 1992-08-18 Bayer Aktiengesellschaft Antibacterial 5-alkylquinolonecarboxylic acids
US5110933A (en) 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
KR920004385A (ko) 1990-08-09 1992-03-27 와꾸나가 기스께 신규 삼환화합물 또는 그의 염, 이의 제조방법 및 이를 함유하는 항균제
US5412098A (en) 1991-12-27 1995-05-02 Wakunaga Seiyaku Kabushiki Kaisha Quinolone derivative or salt thereof and antibacterial containing the same
CA2130937A1 (en) 1992-04-03 1993-10-14 Gordon L. Bundy Pharmaceutically active bicyclic-heterocyclic amines
IT1271350B (it) 1993-01-29 1997-05-27 Riace Establischment Derivati di 3,8 diazabiciclo (3,2,1) - ottani quali medicamenti ad attivita' analgesica centrale
TW301607B (sv) 1993-03-09 1997-04-01 Takeda Pharm Industry Co Ltd
TW273551B (sv) 1993-05-24 1996-04-01 Wakiei Seiyaku Kk
US5468858A (en) 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
CN1046515C (zh) * 1993-12-29 1999-11-17 辉瑞大药厂 二氮杂双环神经激肽拮抗剂
DE4402931A1 (de) 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh Neue 3-Phenylsulfonyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel
IT1274018B (it) 1994-02-23 1997-07-14 Riace Ets Derivati del 3,8-diazabiciclo(3.2.1.)ottano ad attivita' analgesica
US5763437A (en) 1994-07-29 1998-06-09 Fujisawa Pharmaceutical Co., Ltd. Benzodiazepine derivatives
GB2295387A (en) 1994-11-23 1996-05-29 Glaxo Inc Quinazoline antagonists of alpha 1c adrenergic receptors
CA2218503C (en) 1995-04-20 2001-07-24 Pfizer Inc. Arylsulfonyl hydroxamic acid derivatives
FR2733984B1 (fr) 1995-05-10 1997-07-04 Rhone Poulenc Rorer Sa Derives de tryptamine, leur preparation et les medicaments les contenant
PT825186E (pt) 1996-08-16 2002-08-30 Pfizer Derivados de 2-aminobenzazepina e sua utilizacao para o tratamento da imunossupressao
SE9704709D0 (sv) 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
IL145364A0 (en) * 1999-04-01 2002-06-30 Pfizer Prod Inc Aminopyrimidines as sorbitol dehydrogenase inhibitors

Also Published As

Publication number Publication date
JP2004511559A (ja) 2004-04-15
US7012074B2 (en) 2006-03-14
US20040023971A1 (en) 2004-02-05
AU2001296173A1 (en) 2002-04-29
EP1328526A1 (en) 2003-07-23
WO2002032902A1 (en) 2002-04-25

Similar Documents

Publication Publication Date Title
SE9704709D0 (sv) Pharmaceutically active compounds
AP1536A (en) New oxabispidine compounds useful in the treatment of cardiac arrhythmias.
ECSP044992A (es) Inhibidores de la alquín-aril fosfodiesterasa-4
SE0100326D0 (sv) New compounds
BR0114045A (pt) Poliarilcarboxamidas úteis como agentes redutores de lipìdeos
SE0004245D0 (sv) Novel compounds and their use
CA2370244A1 (en) Piperidine derivatives
AU3850600A (en) Dalda analogs and their use
MY133785A (en) Azabicyclooctane derivatives useful in the treatment of cardiac arrhythmias
TR200201128T2 (tr) PDE4 inhibitörleri olarak tetrahidrotiyopiranfitalazinon türevleri.
TW200612907A (en) New compounds
SE0003795D0 (sv) Pharmaceutically useful compounds
CA2412596A1 (en) Cyclic gmp-specific phosphodiesterase inhibitors
NO20031414L (no) Ny oksabispidinforbindelse som er nyttig i behandlingen av hjertearrytmier
DK1204659T3 (da) Serotonerge benzofuraner
DE50101861D1 (de) Tocotrienolchinon- zyklisierungsprodukte mit antihypercholesterin wirkung
DK1204658T3 (da) Benzofurylpiperazin-serotoninagonister
SE9902268D0 (sv) Pharmaceutically active compounds
UA85232C2 (ru) Оксабиспидиновые соединения и их применение в лечении сердечных аритмий
DE60121048D1 (de) PYRAZINOi1'2':1,6öPYRIDOi3,4-BöINDOLDERIVATE
AU2566101A (en) Compounds and methods for the treatment of pain
SE9902270D0 (sv) Pharmaceutically active compounds
SE0002603D0 (sv) New compounds
HRP20010885B1 (en) Ethanesulfonyl-piperidine derivatives
SE9902269D0 (sv) Pharmaceutically active compounds