US7591994B2
(en)
|
2002-12-13 |
2009-09-22 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
US8435529B2
(en)
|
2002-06-14 |
2013-05-07 |
Immunomedics, Inc. |
Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy
|
US8877901B2
(en)
|
2002-12-13 |
2014-11-04 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
US8361464B2
(en)
|
2002-03-01 |
2013-01-29 |
Immunomedics, Inc. |
Anthracycline-Antibody Conjugates for Cancer Therapy
|
US8658773B2
(en)
|
2011-05-02 |
2014-02-25 |
Immunomedics, Inc. |
Ultrafiltration concentration of allotype selected antibodies for small-volume administration
|
US20160279239A1
(en)
|
2011-05-02 |
2016-09-29 |
Immunomedics, Inc. |
Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease
|
US9770517B2
(en)
|
2002-03-01 |
2017-09-26 |
Immunomedics, Inc. |
Anti-Trop-2 antibody-drug conjugates and uses thereof
|
US9745380B2
(en)
*
|
2002-03-01 |
2017-08-29 |
Immunomedics, Inc. |
RS7 antibodies
|
KR20050008788A
(ko)
*
|
2002-06-05 |
2005-01-21 |
파마시아 앤드 업존 캄파니 엘엘씨 |
고처리량 스크리닝을 위한 불소 nmr의 용도
|
US7597876B2
(en)
*
|
2007-01-11 |
2009-10-06 |
Immunomedics, Inc. |
Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
|
US7993626B2
(en)
*
|
2007-01-11 |
2011-08-09 |
Immunomedics, Inc. |
Methods and compositions for F-18 labeling of proteins, peptides and other molecules
|
CA2501616C
(en)
*
|
2002-10-08 |
2015-05-12 |
Immunomedics, Inc. |
Antibody therapy
|
WO2004054622A1
(en)
*
|
2002-12-13 |
2004-07-01 |
Immunomedics, Inc. |
Immunoconjugates with an intracellularly-cleavable linkage
|
US8420086B2
(en)
|
2002-12-13 |
2013-04-16 |
Immunomedics, Inc. |
Camptothecin conjugates of anti-CD22 antibodies for treatment of B cell diseases
|
US20040202666A1
(en)
*
|
2003-01-24 |
2004-10-14 |
Immunomedics, Inc. |
Anti-cancer anthracycline drug-antibody conjugates
|
CA2514277C
(en)
*
|
2003-01-31 |
2015-01-20 |
Immunomedics, Inc. |
Methods and compositions for administering therapeutic and diagnostic agents
|
US20070128117A1
(en)
*
|
2003-02-04 |
2007-06-07 |
Bracco International B.V. |
Ultrasound contrast agents and process for the preparation thereof
|
CN2885311Y
(zh)
|
2006-01-18 |
2007-04-04 |
郑成福 |
经尿道光动力疗法***治疗仪
|
US10376711B2
(en)
|
2003-03-14 |
2019-08-13 |
Light Sciences Oncology Inc. |
Light generating guide wire for intravascular use
|
JP5026072B2
(ja)
*
|
2003-07-01 |
2012-09-12 |
イミューノメディクス、インコーポレイテッド |
二重特異性抗体の多価キャリヤー
|
WO2005027808A1
(en)
|
2003-09-12 |
2005-03-31 |
Z-Medica Corporation |
Calcium zeolite hemostatic agent
|
US20060228331A1
(en)
|
2003-10-10 |
2006-10-12 |
Novo Nordisk A/S |
IL-21 Derivatives and variants
|
WO2005037306A1
(en)
*
|
2003-10-17 |
2005-04-28 |
Novo Nordisk A/S |
Combination therapy
|
US9481878B2
(en)
|
2004-02-13 |
2016-11-01 |
Immunomedics, Inc. |
Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity
|
US9550838B2
(en)
|
2004-02-13 |
2017-01-24 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
US8883160B2
(en)
*
|
2004-02-13 |
2014-11-11 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
JP5150103B2
(ja)
*
|
2004-02-13 |
2013-02-20 |
イミューノメディクス、インコーポレイテッド |
組み換え細胞毒性RNAseを含む融合タンパク質
|
US8551480B2
(en)
|
2004-02-13 |
2013-10-08 |
Immunomedics, Inc. |
Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity
|
EP1853326B1
(en)
|
2005-02-15 |
2016-06-15 |
Virginia Commonwealth University |
Mineral technologies (mt) for acute hemostasis and for the treatment of acute wounds and chronic ulcers
|
US20160355591A1
(en)
|
2011-05-02 |
2016-12-08 |
Immunomedics, Inc. |
Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies
|
US10058621B2
(en)
|
2015-06-25 |
2018-08-28 |
Immunomedics, Inc. |
Combination therapy with anti-HLA-DR antibodies and kinase inhibitors in hematopoietic cancers
|
US9707302B2
(en)
|
2013-07-23 |
2017-07-18 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
US9326995B2
(en)
|
2005-04-04 |
2016-05-03 |
The Regents Of The University Of California |
Oxides for wound healing and body repair
|
BRPI0614366A2
(pt)
*
|
2005-08-11 |
2009-10-06 |
Arpi Matossian Rogers |
peptìdeo, anticorpo ou fragmento de anticorpo, anticorpo ou ligante funcionalmente equivalente, molécula de ácido nucleico, vetor, célula hospedeira, métodos para expressar um peptìdeo, um anticorpo ou fragmento de anticorpo, um anticorpo ou ligante equivalente e para tratar uma doença em um paciente, composição farmacêutica, composição de vacina, métodos de vacinação de um indivìduo contra uma doença ou um distúrbio e de diagnose de um indivìduo para a presença de anticorpos autoimunes, e, arranjo de peptìdeos
|
AU2007209201A1
(en)
*
|
2006-01-24 |
2007-08-02 |
Domantis Limited |
Fusion proteins that contain natural junctions
|
US20080213267A1
(en)
*
|
2006-02-24 |
2008-09-04 |
Arius Research, Inc. |
Cytotoxicity mediation of cells evidencing surface expression of TROP-2
|
US20080305104A1
(en)
*
|
2006-02-24 |
2008-12-11 |
Young David S F |
Cytotoxicity mediation of cells evidencing surface expression of TROP-2
|
US7420040B2
(en)
*
|
2006-02-24 |
2008-09-02 |
Arius Research Inc. |
Cytotoxicity mediation of cells evidencing surface expression of TROP-2
|
US20080131428A1
(en)
*
|
2006-02-24 |
2008-06-05 |
Arius Research, Inc. |
Cytotoxicity mediation of cells evidencing surface expression of TROP-2
|
US8938898B2
(en)
|
2006-04-27 |
2015-01-27 |
Z-Medica, Llc |
Devices for the identification of medical products
|
US7604819B2
(en)
|
2006-05-26 |
2009-10-20 |
Z-Medica Corporation |
Clay-based hemostatic agents and devices for the delivery thereof
|
US20100009390A1
(en)
*
|
2008-05-09 |
2010-01-14 |
The Regents Of The University Of California |
Mutant antibodies with high affinity for egfr
|
US20100008978A1
(en)
*
|
2008-05-09 |
2010-01-14 |
The Regents Of The University Of California |
Nanoparticles effective for internalization into cells
|
US7993640B2
(en)
|
2008-08-06 |
2011-08-09 |
Light Sciences Oncology, Inc. |
Enhancement of light activated therapy by immune augmentation using anti-CTLA-4 antibody
|
JP2012504961A
(ja)
|
2008-10-06 |
2012-03-01 |
ミネルバ バイオテクノロジーズ コーポレーション |
Muc1*抗体
|
EP2386062B1
(en)
*
|
2009-01-09 |
2016-01-06 |
Oxford Biomedica (UK) Ltd |
Factors
|
AU2009339664B2
(en)
*
|
2009-02-05 |
2014-12-04 |
Oncoxx Biotech S.R.L. |
Anti-Trop-2 monoclonal antibodies and uses thereof in the treatment and diagnosis of tumors
|
EP3243527B1
(en)
|
2009-02-13 |
2019-06-05 |
Immunomedics, Inc. |
Immunoconjugates with an intracellularly-cleavable linkage
|
CN104877026B
(zh)
|
2009-03-10 |
2019-10-25 |
比奥根Ma公司 |
抗-bcma抗体
|
WO2010121125A1
(en)
|
2009-04-17 |
2010-10-21 |
Wake Forest University Health Sciences |
Il-13 receptor binding peptides
|
NZ597512A
(en)
*
|
2009-07-16 |
2014-03-28 |
Beckman Coulter Inc |
Novel fluorescent dyes and uses thereof
|
IN2012DN01662A
(da)
*
|
2009-08-31 |
2015-06-05 |
Immunomedics Inc |
|
CA2774260C
(en)
|
2009-09-16 |
2018-10-09 |
Immunomedics, Inc. |
Class i anti-cea antibodies and uses thereof
|
EP2506881B1
(en)
*
|
2009-12-02 |
2024-03-06 |
Immunomedics, Inc. |
Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy
|
US8663950B2
(en)
|
2010-01-11 |
2014-03-04 |
Arizona Board Of Regents |
Production of a monoclonal antibody therapeutic against west nile virus in plants
|
US8362207B2
(en)
|
2010-04-16 |
2013-01-29 |
Wake Forest University Health Sciences |
Multi-level specific targeting of cancer cells with IL-13
|
ES2664809T3
(es)
*
|
2010-05-17 |
2018-04-23 |
Chiome Bioscience Inc. |
Anticuerpo anti-TROP-2 humano que tiene actividad antitumoral in vivo
|
EP2594589A1
(en)
*
|
2010-06-10 |
2013-05-22 |
Sapporo Medical University |
ANTI-Trop-2 ANTIBODY
|
EP3443985B1
(en)
*
|
2010-08-23 |
2020-12-16 |
XBiotech, Inc |
Treatment for neoplastic diseases
|
US8858969B2
(en)
|
2010-09-22 |
2014-10-14 |
Z-Medica, Llc |
Hemostatic compositions, devices, and methods
|
TR201810703T4
(tr)
*
|
2011-03-25 |
2018-08-27 |
Hoffmann La Roche |
Yeni protein saflaştırma yöntemleri.
|
WO2013006244A1
(en)
*
|
2011-06-08 |
2013-01-10 |
Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University |
Bispecific monoclonal antibody therapeutics against west nile virus with improved cns penetration
|
DK3006464T3
(da)
|
2011-06-10 |
2018-09-17 |
Canada Minister Nat Defence |
Antiricin-antistoffer og anvendelser dera
|
EP2776470A2
(en)
|
2011-11-11 |
2014-09-17 |
Rinat Neuroscience Corporation |
Antibodies specific for trop-2 and their uses
|
US9427464B2
(en)
*
|
2011-11-22 |
2016-08-30 |
Chiome Bioscience Inc. |
Anti-human TROP-2 antibody having an antitumor activity in vivo
|
BR112014031439A8
(pt)
|
2012-06-22 |
2023-01-31 |
Z Medica Llc |
Dispositivos e curativos hemostáticos e para feridas e processos para produzir dispositivo hemostático e para tratar feridas
|
US9382329B2
(en)
|
2012-08-14 |
2016-07-05 |
Ibc Pharmaceuticals, Inc. |
Disease therapy by inducing immune response to Trop-2 expressing cells
|
US9682143B2
(en)
|
2012-08-14 |
2017-06-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
US20150231241A1
(en)
|
2012-08-14 |
2015-08-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
US9315567B2
(en)
|
2012-08-14 |
2016-04-19 |
Ibc Pharmaceuticals, Inc. |
T-cell redirecting bispecific antibodies for treatment of disease
|
CA2882449C
(en)
|
2012-08-21 |
2018-09-04 |
Ronghui Lin |
Haptens of aripiprazole and their use in immunoassays
|
EP2888285B1
(en)
|
2012-08-21 |
2024-04-17 |
Janssen Pharmaceutica NV |
Antibodies to aripiprazole haptens and use thereof
|
WO2014031645A1
(en)
|
2012-08-21 |
2014-02-27 |
Ortho-Clinical Diagnostics, Inc |
Antibodies to risperidone haptens and use thereof
|
PL2888373T3
(pl)
|
2012-08-21 |
2018-08-31 |
Janssen Pharmaceutica Nv |
Przeciwciała dla arypiprazolu i ich zastosowanie
|
US10744129B2
(en)
|
2012-12-13 |
2020-08-18 |
Immunomedics, Inc. |
Therapy of small-cell lung cancer (SCLC) with a topoisomerase-I inhibiting antibody-drug conjugate (ADC) targeting Trop-2
|
US9107960B2
(en)
|
2012-12-13 |
2015-08-18 |
Immunimedics, Inc. |
Antibody-SN-38 immunoconjugates with a CL2A linker
|
US9492566B2
(en)
|
2012-12-13 |
2016-11-15 |
Immunomedics, Inc. |
Antibody-drug conjugates and uses thereof
|
US9931417B2
(en)
|
2012-12-13 |
2018-04-03 |
Immunomedics, Inc. |
Antibody-SN-38 immunoconjugates with a CL2A linker
|
US10413539B2
(en)
|
2012-12-13 |
2019-09-17 |
Immunomedics, Inc. |
Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132)
|
US10137196B2
(en)
|
2012-12-13 |
2018-11-27 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
|
HRP20220399T1
(hr)
|
2012-12-13 |
2022-05-13 |
Immunomedics, Inc. |
Režim doziranja imunokonjugata protutijela i sn-38 za poboljšanu učinkovitost i smanjenu toksičnost
|
US10206918B2
(en)
|
2012-12-13 |
2019-02-19 |
Immunomedics, Inc. |
Efficacy of anti-HLA-DR antiboddy drug conjugate IMMU-140 (hL243-CL2A-SN-38) in HLA-DR positive cancers
|
US8877202B2
(en)
|
2013-02-07 |
2014-11-04 |
Immunomedics, Inc. |
Pro-drug form (P2PDOX) of the highly potent 2-pyrrolinodoxorubicin conjugated to antibodies for targeted therapy of cancer
|
EP2774930A1
(en)
|
2013-03-07 |
2014-09-10 |
Aptenia S.R.L. |
Metallocene compounds and labeled molecules comprising the same for in vivo imaging.
|
WO2014152361A1
(en)
|
2013-03-15 |
2014-09-25 |
Wake Forest University Health Sciences |
Antibodies against human and canine il-13ra2
|
US11253606B2
(en)
|
2013-07-23 |
2022-02-22 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
CA2920192A1
(en)
*
|
2013-09-27 |
2015-04-02 |
Immunomedics, Inc. |
Anti-trop-2 antibody-drug conjugates and uses thereof
|
TN2016000137A1
(en)
|
2013-10-18 |
2017-10-06 |
Deutsches Krebsforsch |
Labeled inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer.
|
WO2015070210A1
(en)
|
2013-11-11 |
2015-05-14 |
Wake Forest University Health Sciences |
Epha3 and multi-valent targeting of tumors
|
AU2014371934B2
(en)
|
2013-12-25 |
2020-01-23 |
Daiichi Sankyo Company, Limited |
Anti-TROP2 antibody-drug conjugate
|
WO2015113055A2
(en)
|
2014-01-27 |
2015-07-30 |
Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University |
Plant-derived antibodies and derivatives that reduce risk of antibody-dependent enhancement (ade) of infection
|
MX2016010683A
(es)
*
|
2014-02-21 |
2017-05-11 |
Ibc Pharmaceuticals Inc |
Terapia para tratar enfermedades mediante la induccion de respuesta inmune de las células que expresan trop-2.
|
CN106029098A
(zh)
|
2014-02-25 |
2016-10-12 |
免疫医疗公司 |
人源化rfb4抗cd22抗体
|
SG11201608194VA
(en)
|
2014-04-03 |
2016-10-28 |
Igm Biosciences Inc |
Modified j-chain
|
CN112851822A
(zh)
*
|
2014-04-09 |
2021-05-28 |
广州复能基因有限公司 |
一种人重组乙型干扰素融合蛋白
|
US9580495B2
(en)
|
2014-06-24 |
2017-02-28 |
Immunomedics, Inc. |
Anti-histone therapy for vascular necrosis in severe glomerulonephritis
|
US10442863B2
(en)
|
2014-09-08 |
2019-10-15 |
Lutana Gmbh |
Construct for the delivery of a molecule into the cytoplasm of a cell
|
CN106999517A
(zh)
|
2014-10-07 |
2017-08-01 |
免疫医疗公司 |
抗体‑药物缀合物的新辅助剂用途
|
US10501555B2
(en)
|
2014-12-04 |
2019-12-10 |
Abruzzo Theranostic S.R.L. |
Humanized anti-trop-2 monoclonal antibodies and uses thereof
|
JP6895890B2
(ja)
|
2015-02-10 |
2021-06-30 |
ミネルバ バイオテクノロジーズ コーポレーション |
ヒト化抗muc1* 抗体
|
MX2017013383A
(es)
|
2015-04-20 |
2017-12-07 |
Tolero Pharmaceuticals Inc |
Prediccion de respuesta a alvocidib mediante perfilado mitocondrial.
|
EP3286224A4
(en)
|
2015-04-22 |
2018-11-14 |
Immunomedics, Inc. |
Isolation, detection, diagnosis and/or characterization of circulating trop-2-positive cancer cells
|
KR102608921B1
(ko)
|
2015-05-18 |
2023-12-01 |
스미토모 파마 온콜로지, 인크. |
생체 이용률이 증가된 알보시딥 프로드러그
|
CN107708741A
(zh)
*
|
2015-06-12 |
2018-02-16 |
免疫医疗公司 |
用嵌合抗原受体(car)构建体和表达car构建体的t细胞(car‑t)或nk细胞(car‑nk)进行的疾病疗法
|
US10195175B2
(en)
|
2015-06-25 |
2019-02-05 |
Immunomedics, Inc. |
Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors
|
WO2016210108A1
(en)
|
2015-06-25 |
2016-12-29 |
Immunomedics, Inc. |
Combining anti-hla-dr or anti-trop-2 antibodies with microtubule inhibitors, parp inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
KR20180021723A
(ko)
|
2015-06-29 |
2018-03-05 |
다이이찌 산쿄 가부시키가이샤 |
항체-약물 콘주게이트의 선택적 제조 방법
|
SI3316885T1
(sl)
|
2015-07-01 |
2021-09-30 |
Immunomedics, Inc. |
Imunokonjugati protitelo-SN-38 z linkerjem CL2A
|
MX2018001289A
(es)
|
2015-08-03 |
2018-04-30 |
Tolero Pharmaceuticals Inc |
Terapias de combinacion para el tratamiento del cancer.
|
US10618978B2
(en)
|
2015-09-30 |
2020-04-14 |
Igm Biosciences, Inc. |
Binding molecules with modified J-chain
|
ES2819870T3
(es)
|
2015-09-30 |
2021-04-19 |
Igm Biosciences Inc |
Moléculas de unión con cadena J modificada
|
AU2016379292B2
(en)
|
2015-12-24 |
2021-03-25 |
Kyowa Kirin Co., Ltd. |
α, β unsaturated amide compound
|
CA3011372A1
(en)
|
2016-02-10 |
2017-08-17 |
Immunomedics, Inc. |
Combination of abcg2 inhibitors with sacituzumab govitecan (immu-132) overcomes resistance to sn-38 in trop-2 expressing cancers
|
WO2017189279A1
(en)
|
2016-04-27 |
2017-11-02 |
Immunomedics, Inc. |
Efficacy of anti-trop-2-sn-38 antibody drug conjugates for therapy of tumors relapsed/refractory to checkpoint inhibitors
|
CN115317603A
(zh)
|
2016-07-07 |
2022-11-11 |
小利兰·斯坦福大学托管委员会 |
抗体佐剂缀合物
|
WO2018036438A1
(zh)
*
|
2016-08-23 |
2018-03-01 |
四川科伦博泰生物医药股份有限公司 |
一种抗体-药物偶联物及其制备方法和应用
|
JP6786973B2
(ja)
*
|
2016-09-08 |
2020-11-18 |
ブラザー工業株式会社 |
画像解析装置
|
CN108066772B
(zh)
*
|
2016-11-14 |
2021-07-13 |
中国科学院上海药物研究所 |
靶向tacstd2的抗体与药物偶联体(adc)分子
|
US11279694B2
(en)
|
2016-11-18 |
2022-03-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
WO2018110515A1
(ja)
|
2016-12-12 |
2018-06-21 |
第一三共株式会社 |
抗体-薬物コンジュゲートと免疫チェックポイント阻害剤の組み合わせ
|
US10132797B2
(en)
|
2016-12-19 |
2018-11-20 |
Tolero Pharmaceuticals, Inc. |
Profiling peptides and methods for sensitivity profiling
|
MX2019008059A
(es)
|
2017-01-17 |
2019-12-11 |
Daiichi Sankyo Co Ltd |
Anticuerpo anti-gpr20 y conjugado de anticuerpo-medicamento anti-gpr20.
|
AU2018224319B2
(en)
*
|
2017-02-27 |
2024-04-04 |
Dragonfly Therapeutics, Inc. |
Multispecific binding proteins targeting CEA
|
WO2018183041A1
(en)
|
2017-03-27 |
2018-10-04 |
Immunomedics, Inc. |
Treatment of trop-2 expressing triple negative breast cancer with sacituzumab govitecan and a rad51 inhibitor
|
EP3606964A4
(en)
|
2017-04-03 |
2020-12-09 |
Immunomedics, Inc. |
SUBCUTANE ADMINISTRATION OF ANTIBODY DRUG CONJUGATES FOR CANCER THERAPY
|
US11207420B2
(en)
|
2017-04-19 |
2021-12-28 |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. |
Cytotoxin and conjugate, uses of same and preparation method therefor
|
CN107446050A
(zh)
*
|
2017-08-11 |
2017-12-08 |
百奥泰生物科技(广州)有限公司 |
Trop2阳性疾病治疗的化合物及方法
|
CN111051330A
(zh)
|
2017-08-31 |
2020-04-21 |
第一三共株式会社 |
抗体-药物缀合物的改进制备方法
|
US11318212B2
(en)
|
2017-08-31 |
2022-05-03 |
Daiichi Sankyo Company, Limited |
Method for producing antibody-drug conjugate
|
WO2019055579A1
(en)
|
2017-09-12 |
2019-03-21 |
Tolero Pharmaceuticals, Inc. |
TREATMENT REGIME FOR CANCERS THAT ARE INSENSITIVE TO BCL-2 INHIBITORS USING THE MCL-1 ALVOCIDIB INHIBITOR
|
CN111164208B
(zh)
|
2017-09-29 |
2023-08-04 |
第一三共株式会社 |
抗体-吡咯并苯并二氮杂卓衍生物偶联物
|
CA3080236A1
(en)
|
2017-12-15 |
2019-06-20 |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. |
Bioactive molecule conjugate, preparation method and use thereof
|
CN108680750A
(zh)
*
|
2017-12-29 |
2018-10-19 |
广西壮族自治区人民医院 |
Trop2蛋白表达量的elisa检测方法及试剂盒
|
WO2019148186A1
(en)
*
|
2018-01-29 |
2019-08-01 |
Silarus Therapeutics, Inc. |
Antibodies binding erfe and methods of use
|
EP3794041B1
(en)
|
2018-05-18 |
2023-07-12 |
Glycotope GmbH |
Anti-muc1 antibody
|
US20210340628A1
(en)
|
2018-08-23 |
2021-11-04 |
Daiichi Sankyo Company, Limited |
Sensitivity marker for antibody-drug conjugate
|
MX2021003184A
(es)
|
2018-09-26 |
2021-08-11 |
Ascendis Pharma As |
Hidrogeles de acido hialuronico degradables.
|
CN113260384A
(zh)
|
2018-11-05 |
2021-08-13 |
西纳福克斯股份有限公司 |
用于靶向表达trop-2的肿瘤的抗体缀合物
|
MX2021006544A
(es)
|
2018-12-04 |
2021-07-07 |
Sumitomo Pharma Oncology Inc |
Inhibidores de cinasa dependiente de ciclina 9 (cdk9) y polimorfos de los mismos para uso como agentes para el tratamiento de cancer.
|
AU2020205100A1
(en)
*
|
2019-01-04 |
2021-08-19 |
Trio Pharmaceuticals, Inc. |
Multi-specific protein molecules and uses thereof
|
WO2020190725A1
(en)
|
2019-03-15 |
2020-09-24 |
Bolt Biotherapeutics, Inc. |
Immunoconjugates targeting her2
|
WO2020191326A1
(en)
|
2019-03-20 |
2020-09-24 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (aml) with venetoclax failure
|
WO2020196474A1
(ja)
|
2019-03-25 |
2020-10-01 |
第一三共株式会社 |
抗体-ピロロベンゾジアゼピン誘導体コンジュゲート
|
TW202102226A
(zh)
|
2019-03-27 |
2021-01-16 |
日商第一三共股份有限公司 |
抗體-吡咯并苯二氮呯衍生物結合物及parp抑制劑之組合
|
SG11202112429PA
(en)
|
2019-05-29 |
2021-12-30 |
Daiichi Sankyo Co Ltd |
Dosage of an antibody-drug conjugate
|
JP2023503943A
(ja)
|
2019-11-27 |
2023-02-01 |
エーエルエックス オンコロジー インコーポレイテッド |
がんを治療するための組み合わせ療法
|
US20230101735A1
(en)
|
2020-01-22 |
2023-03-30 |
Jiangsu Hengrui Medicine Co., Ltd. |
Anti-trop-2 antidody-exatecan analog conjugate and medical use thereof
|
JP2023511163A
(ja)
|
2020-01-22 |
2023-03-16 |
上海森輝医薬有限公司 |
エリブリン誘導体の薬物複合体、その調製方法及びその医薬的応用
|
CA3176095A1
(en)
|
2020-03-20 |
2021-09-23 |
Immunomedics, Inc. |
Biomarkers for sacituzumab govitecan therapy
|
TW202200212A
(zh)
|
2020-05-03 |
2022-01-01 |
中國大陸商聯寧(蘇州)生物製藥有限公司 |
包含抗-trop-2抗體之抗體藥物結合物
|
WO2021226440A1
(en)
|
2020-05-08 |
2021-11-11 |
Bolt Biotherapeutics, Inc. |
Elastase-substrate, peptide linker immunoconjugates, and uses thereof
|
WO2022010797A2
(en)
|
2020-07-07 |
2022-01-13 |
Bionecure Therapeutics, Inc. |
Novel maytansinoids as adc payloads and their use for the treatment of cancer
|
JP2023533173A
(ja)
|
2020-07-09 |
2023-08-02 |
エフ. ホフマン-ラ ロシュ アーゲー |
タンパク質の濃縮組成物、それらの調製及びそれらの使用
|
CA3186059A1
(en)
|
2020-08-13 |
2022-02-17 |
Romas Kudirka |
Pyrazoloazepine immunoconjugates, and uses thereof
|
CA3197423A1
(en)
|
2020-11-04 |
2022-05-12 |
Daniel Getts |
Engineered chimeric fusion protein compositions and methods of use thereof
|
IT202000031838A1
(it)
|
2020-12-22 |
2022-06-22 |
Saverio Alberti |
Piattaforma per ottenere anticorpi monoclonali diretti contro antigeni processati tumore-specifici
|
KR20230147105A
(ko)
|
2021-01-28 |
2023-10-20 |
진콴텀 헬스케어 (쑤저우) 씨오., 엘티디. |
리가제 융합 단백질 및 그 응용
|
IL306114A
(en)
|
2021-03-26 |
2023-11-01 |
Bolt Biotherapeutics Inc |
2-amino-4-carboxamide-benzazepine immunoconjugates and uses thereof
|
WO2022204536A1
(en)
|
2021-03-26 |
2022-09-29 |
Bolt Biotherapeutics, Inc. |
2-amino-4-carboxamide-benzazepine immunoconjugates, and uses thereof
|
CA3173758A1
(en)
|
2021-04-29 |
2022-11-03 |
Hui Zhang |
Preparation method and application of antibody drug conjugate
|
EP4342497A1
(en)
|
2021-05-10 |
2024-03-27 |
Kawasaki Institute of Industrial Promotion |
Antibody having reduced binding affinity for antigen
|
EP4337190A1
(en)
|
2021-05-13 |
2024-03-20 |
ALX Oncology Inc. |
Combination therapies for treating cancer
|
TW202313094A
(zh)
|
2021-05-18 |
2023-04-01 |
美商基利科學股份有限公司 |
使用FLT3L—Fc融合蛋白之方法
|
EP4349371A1
(en)
|
2021-06-02 |
2024-04-10 |
Bio-Thera Solutions, Ltd. |
Drug conjugate and use thereof
|
CA3222269A1
(en)
|
2021-06-11 |
2022-12-15 |
Gilead Sciences, Inc. |
Combination mcl-1 inhibitors with anti-cancer agents
|
WO2022261310A1
(en)
|
2021-06-11 |
2022-12-15 |
Gilead Sciences, Inc. |
Combination mcl-1 inhibitors with anti-body drug conjugates
|
WO2022266660A1
(en)
|
2021-06-17 |
2022-12-22 |
Amberstone Biosciences, Inc. |
Anti-cd3 constructs and uses thereof
|
AU2022314086A1
(en)
|
2021-07-21 |
2024-02-22 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Pharmaceutical composition containing anti-trop2 antibody drug conjugate and use thereof
|
CA3228311A1
(en)
|
2021-08-12 |
2023-02-16 |
Ke HE |
Bispecific recombinant protein and use thereof
|
WO2023016488A1
(zh)
|
2021-08-13 |
2023-02-16 |
昆山新蕴达生物科技有限公司 |
一种基于微管抑制剂的抗体偶联药物
|
CN117881431A
(zh)
|
2021-08-24 |
2024-04-12 |
昆山新蕴达生物科技有限公司 |
一种由可断裂连接子偶联的抗体偶联药物
|
TW202330504A
(zh)
|
2021-10-28 |
2023-08-01 |
美商基利科學股份有限公司 |
嗒𠯤—3(2h)—酮衍生物
|
US11919869B2
(en)
|
2021-10-29 |
2024-03-05 |
Gilead Sciences, Inc. |
CD73 compounds
|
WO2023076599A1
(en)
|
2021-10-29 |
2023-05-04 |
Bolt Biotherapeutics, Inc. |
Tlr agonist immunoconjugates with cysteine-mutant antibodies, and uses thereof
|
CN116199784A
(zh)
*
|
2021-11-30 |
2023-06-02 |
泽达生物医药有限公司 |
抗trop-2/pd-l1双特异性抗体
|
WO2023122615A1
(en)
|
2021-12-22 |
2023-06-29 |
Gilead Sciences, Inc. |
Ikaros zinc finger family degraders and uses thereof
|
US20240124412A1
(en)
|
2021-12-22 |
2024-04-18 |
Gilead Sciences, Inc. |
Ikaros zinc finger family degraders and uses thereof
|
TW202340168A
(zh)
|
2022-01-28 |
2023-10-16 |
美商基利科學股份有限公司 |
Parp7抑制劑
|
US20240059786A1
(en)
*
|
2022-02-24 |
2024-02-22 |
Xencor, Inc. |
Anti-cd28 x anti-trop2 antibodies
|
WO2023178181A1
(en)
|
2022-03-17 |
2023-09-21 |
Gilead Sciences, Inc. |
Ikaros zinc finger family degraders and uses thereof
|
WO2023180485A1
(en)
|
2022-03-23 |
2023-09-28 |
Synaffix B.V. |
Antibody-conjugates for targeting of tumours expressing trop-2
|
US20230355796A1
(en)
|
2022-03-24 |
2023-11-09 |
Gilead Sciences, Inc. |
Combination therapy for treating trop-2 expressing cancers
|
WO2023201267A1
(en)
|
2022-04-13 |
2023-10-19 |
Gilead Sciences, Inc. |
Combination therapy for treating trop-2 expressing cancers
|
WO2023201268A1
(en)
|
2022-04-13 |
2023-10-19 |
Gilead Sciences, Inc. |
Combination therapy for treating tumor antigen expressing cancers
|
TW202400138A
(zh)
|
2022-04-21 |
2024-01-01 |
美商基利科學股份有限公司 |
Kras g12d調節化合物
|
WO2023240135A2
(en)
|
2022-06-07 |
2023-12-14 |
Actinium Pharmaceuticals, Inc. |
Bifunctional chelators and conjugates
|
WO2024006929A1
(en)
|
2022-07-01 |
2024-01-04 |
Gilead Sciences, Inc. |
Cd73 compounds
|