DK296477A - Fremgangsmade til fremstilling af 2-brom-6-fluor-n-2-imidazolidinylidenbenzamin eller syreadditionssalte heraf - Google Patents

Fremgangsmade til fremstilling af 2-brom-6-fluor-n-2-imidazolidinylidenbenzamin eller syreadditionssalte heraf

Info

Publication number
DK296477A
DK296477A DK296477A DK296477A DK296477A DK 296477 A DK296477 A DK 296477A DK 296477 A DK296477 A DK 296477A DK 296477 A DK296477 A DK 296477A DK 296477 A DK296477 A DK 296477A
Authority
DK
Denmark
Prior art keywords
benzamine
imidazolidinylidene
bromo
fluoro
procedure
Prior art date
Application number
DK296477A
Other languages
English (en)
Other versions
DK146281B (da
DK146281C (da
Inventor
H Staehle
H Koeppe
W Kummer
W Hoefke
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of DK296477A publication Critical patent/DK296477A/da
Publication of DK146281B publication Critical patent/DK146281B/da
Application granted granted Critical
Publication of DK146281C publication Critical patent/DK146281C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • C07D233/50Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electric Clocks (AREA)
DK296477A 1976-07-03 1977-07-01 Analogifremgangsmaade til fremstilling af 2-brom-6-fluor-n-2-imidazolidinyliden-benzamin eller syreadditionssalte heraf DK146281C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2630060 1976-07-03
DE2630060A DE2630060C2 (de) 1976-07-03 1976-07-03 2-(2-Brom-6-fluor-phenylimino)-imidazolidin, dessen Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung

Publications (3)

Publication Number Publication Date
DK296477A true DK296477A (da) 1978-01-04
DK146281B DK146281B (da) 1983-08-22
DK146281C DK146281C (da) 1984-01-30

Family

ID=5982175

Family Applications (1)

Application Number Title Priority Date Filing Date
DK296477A DK146281C (da) 1976-07-03 1977-07-01 Analogifremgangsmaade til fremstilling af 2-brom-6-fluor-n-2-imidazolidinyliden-benzamin eller syreadditionssalte heraf

Country Status (32)

Country Link
US (1) US4166859A (da)
JP (1) JPS6026108B2 (da)
AT (1) AT354436B (da)
AU (1) AU507260B2 (da)
BE (1) BE856395A (da)
BG (1) BG28049A3 (da)
CA (1) CA1088550A (da)
CH (2) CH633273A5 (da)
CS (1) CS204005B2 (da)
DD (1) DD132965A5 (da)
DE (1) DE2630060C2 (da)
DK (1) DK146281C (da)
ES (4) ES460351A1 (da)
FI (1) FI64146C (da)
FR (1) FR2356642B1 (da)
GB (1) GB1575147A (da)
GR (1) GR63636B (da)
HU (1) HU180429B (da)
IE (1) IE45109B1 (da)
IL (1) IL52433A (da)
LU (1) LU77679A1 (da)
MX (1) MX4841E (da)
NL (2) NL188643C (da)
NO (2) NO145951C (da)
NZ (1) NZ184539A (da)
PH (1) PH14572A (da)
PL (1) PL102918B1 (da)
PT (1) PT66756B (da)
SE (1) SE431871B (da)
SU (2) SU680644A3 (da)
YU (1) YU161977A (da)
ZA (1) ZA773979B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2806811A1 (de) * 1978-02-17 1979-08-23 Boehringer Sohn Ingelheim Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben
DE2806775A1 (de) * 1978-02-17 1979-08-30 Boehringer Sohn Ingelheim Neue substituierte 2-phenylimino- imidazolidine deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
US4644007A (en) * 1981-11-20 1987-02-17 Alcon Laboratories, Inc. 3-chloro-4-(4,5-dihydro-1H-imidazo-2-yl)-amino-5-alkylbenzoic acids, esters, salts, compositions and methods
US4461904A (en) * 1981-11-20 1984-07-24 Alcon Laboratories, Inc. 2-(Trisubstituted phenylimino)-imidazolines
US4515800A (en) * 1981-11-20 1985-05-07 Icilio Cavero Method of lowering intraocular pressure using phenylimino-imidazoles
US4517199A (en) * 1981-11-20 1985-05-14 Alcon Laboratories, Inc. Method for lowering intraocular pressure using phenylimino-imidazoles
DE3437694A1 (de) * 1984-10-15 1986-04-17 Boehringer Ingelheim Vetmedica GmbH, 6507 Ingelheim Verwendung einer substanz als sedativum
US4587257A (en) * 1984-12-14 1986-05-06 Alcon Laboratories, Inc. Control of ocular bleeding using clonidine derivatives
JPH0317363Y2 (da) * 1986-11-19 1991-04-12
US5441339A (en) * 1992-10-22 1995-08-15 Prince Corporation Vehicle light
WO2005000818A1 (en) 2003-06-27 2005-01-06 Warner-Lambert Company Llc 5-substituted-4-`(substituted phenyl)!amino!-2-pyridone deviatives for use as mek inhibitors
CN115784896A (zh) * 2022-11-24 2023-03-14 山东诚创蓝海医药科技有限公司 一种2-溴-6-氟苯胺的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1770874B2 (de) * 1968-07-12 1977-09-15 Veb Arzneimittelwerk Dresden, Ddr 8122 Radebeul Verfahren zur herstellung von 2-(2,6- dichlorphenylamino)-imidazolin-2
BE787683A (fr) * 1971-08-20 1973-02-19 Boehringer Sohn Ingelheim 2-phenylimino-imidazolidines, leurs sels d'addition avec des acides et procedes pour les fabriquer
DE2446758C3 (de) * 1974-10-01 1979-01-04 C.H. Boehringer Sohn, 6507 Ingelheim 2-(2-Fluor-6-trifluormethylphenylimino)-imidazolidin, dessen Säureadditionssalze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung der Hypertonie
DE2542702C2 (de) * 1975-09-25 1983-11-10 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Verfahren zur Herstellung von 1-Benzoyl-2-(2,6-dichlorphenylamino)-2-imidazolin

Also Published As

Publication number Publication date
NL930111I2 (nl) 1995-04-03
FI771972A (da) 1978-01-04
FI64146B (fi) 1983-06-30
SU665800A3 (ru) 1979-05-30
NL188643B (nl) 1992-03-16
PL102918B1 (pl) 1979-05-31
BE856395A (fr) 1978-01-02
MX4841E (es) 1982-10-28
SU680644A3 (ru) 1979-08-15
PT66756B (de) 1979-06-07
NO145951B (no) 1982-03-22
ATA438777A (de) 1979-06-15
FR2356642A1 (fr) 1978-01-27
ZA773979B (en) 1979-03-28
IE45109L (en) 1978-01-03
HU180429B (en) 1983-03-28
PT66756A (de) 1977-08-01
LU77679A1 (da) 1978-09-14
JPS535164A (en) 1978-01-18
PL199298A1 (pl) 1978-03-28
US4166859A (en) 1979-09-04
DD132965A5 (de) 1978-11-22
JPS6026108B2 (ja) 1985-06-21
YU161977A (en) 1983-01-21
FR2356642B1 (fr) 1985-07-19
ES466850A1 (es) 1978-10-01
ES466852A1 (es) 1978-10-01
NO1994024I1 (no) 1994-11-25
CA1088550A (en) 1980-10-28
IL52433A (en) 1980-09-16
NZ184539A (en) 1980-03-05
ES460351A1 (es) 1978-08-16
DE2630060C2 (de) 1984-04-19
SE7707689L (sv) 1978-01-04
PH14572A (en) 1981-09-24
NL930111I1 (nl) 1993-10-18
NL7707308A (nl) 1978-01-05
AU507260B2 (en) 1980-02-07
AU2662077A (en) 1979-01-04
DK146281B (da) 1983-08-22
DK146281C (da) 1984-01-30
ES466851A1 (es) 1978-10-01
NO772329L (no) 1978-01-03
BG28049A3 (en) 1980-02-25
DE2630060A1 (de) 1978-01-12
CH633275A5 (de) 1982-11-30
IE45109B1 (en) 1982-06-16
IL52433A0 (en) 1977-10-31
GB1575147A (en) 1980-09-17
NO145951C (no) 1982-06-30
CS204005B2 (en) 1981-03-31
SE431871B (sv) 1984-03-05
NL188643C (nl) 1992-08-17
GR63636B (en) 1979-11-27
CH633273A5 (de) 1982-11-30
AT354436B (de) 1979-01-10
FI64146C (fi) 1983-10-10

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