DK2248809T3 - Alkyl-3-[2-(benzo[b]thiophen-5-yl)-ethoxy]-propanoater som mellemprodukt i fremstilling af Azetidin-3-ol-derivater - Google Patents

Alkyl-3-[2-(benzo[b]thiophen-5-yl)-ethoxy]-propanoater som mellemprodukt i fremstilling af Azetidin-3-ol-derivater

Info

Publication number
DK2248809T3
DK2248809T3 DK10007872.4T DK10007872T DK2248809T3 DK 2248809 T3 DK2248809 T3 DK 2248809T3 DK 10007872 T DK10007872 T DK 10007872T DK 2248809 T3 DK2248809 T3 DK 2248809T3
Authority
DK
Denmark
Prior art keywords
azetidin
ethoxy
propanoates
thiophen
benzo
Prior art date
Application number
DK10007872.4T
Other languages
English (en)
Inventor
Akihito Saitoh
Yoshiaki Suzuki
Kenji Yonezawa
Mitsuhide Kawamura
Takahiko Kusanagi
Takashi Nakai
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Application granted granted Critical
Publication of DK2248809T3 publication Critical patent/DK2248809T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK10007872.4T 2005-03-28 2006-03-27 Alkyl-3-[2-(benzo[b]thiophen-5-yl)-ethoxy]-propanoater som mellemprodukt i fremstilling af Azetidin-3-ol-derivater DK2248809T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2005090831 2005-03-28
JP2005174738 2005-06-15
JP2005206808 2005-07-15
JP2005230666 2005-08-09
EP06730075A EP1864978A4 (en) 2005-03-28 2006-03-27 PROCESS FOR PRODUCING 1- (3- (2- (1-BENZOTHIOPHEN-5-YL) -ETHOXY) PROPYL) AZETIDIN-3-OL OR ITS SALTS

Publications (1)

Publication Number Publication Date
DK2248809T3 true DK2248809T3 (da) 2012-06-18

Family

ID=37053344

Family Applications (2)

Application Number Title Priority Date Filing Date
DK10007872.4T DK2248809T3 (da) 2005-03-28 2006-03-27 Alkyl-3-[2-(benzo[b]thiophen-5-yl)-ethoxy]-propanoater som mellemprodukt i fremstilling af Azetidin-3-ol-derivater
DK10002020.5T DK2210884T3 (da) 2005-03-28 2006-03-27 Fremgangsmåde til fremstilling af 1-(3-(2-(1-benzothiophen-5-yl)-ethoxy)propionsyre eller salte deraf

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK10002020.5T DK2210884T3 (da) 2005-03-28 2006-03-27 Fremgangsmåde til fremstilling af 1-(3-(2-(1-benzothiophen-5-yl)-ethoxy)propionsyre eller salte deraf

Country Status (22)

Country Link
US (2) US7951963B2 (da)
EP (4) EP2210884B1 (da)
JP (1) JP5031554B2 (da)
KR (2) KR101337382B1 (da)
CN (1) CN101151257B (da)
AT (2) ATE557020T1 (da)
AU (1) AU2006229271B2 (da)
BR (1) BRPI0609496C8 (da)
CA (2) CA2799659C (da)
CY (3) CY1112956T1 (da)
DK (2) DK2248809T3 (da)
ES (3) ES2384312T3 (da)
IL (2) IL186044A (da)
MX (1) MX2007011938A (da)
NO (3) NO340071B1 (da)
NZ (2) NZ561672A (da)
PL (3) PL2248809T3 (da)
PT (3) PT2210884E (da)
SG (1) SG155251A1 (da)
SI (3) SI2348022T1 (da)
WO (1) WO2006104088A1 (da)
ZA (1) ZA200708262B (da)

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US8563573B2 (en) 2007-11-02 2013-10-22 Vertex Pharmaceuticals Incorporated Azaindole derivatives as CFTR modulators
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KR101927556B1 (ko) 2011-03-02 2018-12-10 바이엘 인텔렉쳐 프로퍼티 게엠베하 아릴- 및 헤테로아릴아세트산 유도체의 제조 방법
EP2762225B1 (en) 2011-09-30 2018-09-12 Mitsubishi Chemical Corporation Polymerizable inorganic particle-dispersing agent, inorganic/organic composite particles containing said polymerizable inorganic particle-dispersing agent, and inorganic/organic resin composite
PL2818165T3 (pl) 2012-02-22 2019-09-30 Fujifilm Toyama Chemical Co., Ltd. Stała kompozycja farmaceutyczna zawierająca 1-(3-(2-(1-benzotiofen-5-ylo)etoksy)propylo)-azetydyn-3-ol albo jego sól
US9012496B2 (en) 2012-07-16 2015-04-21 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions of (R)-1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide and administration thereof
SG10201907035TA (en) 2014-01-31 2019-09-27 Fujifilm Toyama Chemical Co Ltd Post nerve injury rehabilitation effect-enhancing agent comprising alkyl ether derivative or salt thereof
ES2957761T3 (es) 2014-04-15 2024-01-25 Vertex Pharma Composiciones farmacéuticas para el tratamiento de enfermedades mediadas por el regulador de la conductancia transmembrana de fibrosis quística
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Also Published As

Publication number Publication date
PT2348022E (pt) 2013-02-13
EP2248809B1 (en) 2012-05-09
EP2348022B1 (en) 2013-01-09
CA2799659A1 (en) 2006-10-05
EP1864978A4 (en) 2009-07-01
AU2006229271A1 (en) 2006-10-05
PT2248809E (pt) 2012-07-02
US20110098484A1 (en) 2011-04-28
EP2210884B1 (en) 2012-02-22
KR20080008334A (ko) 2008-01-23
BRPI0609496C8 (pt) 2021-05-25
NO20074618L (no) 2007-10-25
ATE546443T1 (de) 2012-03-15
CA2600381C (en) 2013-11-12
IL186044A (en) 2013-12-31
BRPI0609496C1 (pt) 2021-05-11
KR20130010090A (ko) 2013-01-25
ATE557020T1 (de) 2012-05-15
SI2210884T1 (sl) 2012-06-29
NO20161418A1 (no) 2007-10-25
PL2210884T3 (pl) 2012-07-31
CA2600381A1 (en) 2006-10-05
CN101151257A (zh) 2008-03-26
US20090069576A1 (en) 2009-03-12
EP2210884A3 (en) 2010-09-22
CA2799659C (en) 2014-12-02
WO2006104088A1 (ja) 2006-10-05
ES2380443T3 (es) 2012-05-11
EP2210884A2 (en) 2010-07-28
ES2398934T3 (es) 2013-03-22
NO340420B1 (no) 2017-04-18
CN101151257B (zh) 2012-07-18
BRPI0609496B1 (pt) 2020-11-24
PL2248809T3 (pl) 2012-10-31
EP2248809A1 (en) 2010-11-10
EP2348022A1 (en) 2011-07-27
AU2006229271B2 (en) 2012-02-09
JPWO2006104088A1 (ja) 2008-09-04
JP5031554B2 (ja) 2012-09-19
NO340071B1 (no) 2017-03-06
KR101337382B1 (ko) 2013-12-06
NZ561672A (en) 2010-04-30
NZ583580A (en) 2010-10-29
KR101283930B1 (ko) 2013-07-16
NO340366B1 (no) 2017-04-10
EP1864978A1 (en) 2007-12-12
IL186044A0 (en) 2008-02-09
SI2348022T1 (sl) 2013-05-31
MX2007011938A (es) 2008-03-14
PL2348022T3 (pl) 2013-06-28
CY1113571T1 (el) 2016-06-22
US7951963B2 (en) 2011-05-31
SI2248809T1 (sl) 2012-09-28
NO20161419A1 (no) 2016-06-07
ZA200708262B (en) 2009-01-28
BRPI0609496A2 (pt) 2011-10-18
DK2210884T3 (da) 2012-03-26
PT2210884E (pt) 2012-04-10
CY1112885T1 (el) 2016-04-13
ES2384312T3 (es) 2012-07-03
US8273902B2 (en) 2012-09-25
IL214245A (en) 2014-12-31
SG155251A1 (en) 2009-09-30
CY1112956T1 (el) 2016-04-13
IL214245A0 (en) 2011-08-31

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