CY1113571T1 - Μεθοδος για την παραγωγη 1-(3-(2-(1-βενζοθειοφαιν-5-υλ)-αιθοξυ)προπυλ)αζετιδιν-3-ολης ή αλατων αυτης - Google Patents

Μεθοδος για την παραγωγη 1-(3-(2-(1-βενζοθειοφαιν-5-υλ)-αιθοξυ)προπυλ)αζετιδιν-3-ολης ή αλατων αυτης

Info

Publication number
CY1113571T1
CY1113571T1 CY20131100075T CY131100075T CY1113571T1 CY 1113571 T1 CY1113571 T1 CY 1113571T1 CY 20131100075 T CY20131100075 T CY 20131100075T CY 131100075 T CY131100075 T CY 131100075T CY 1113571 T1 CY1113571 T1 CY 1113571T1
Authority
CY
Cyprus
Prior art keywords
azetidin
ethoxy
propyl
salts
production
Prior art date
Application number
CY20131100075T
Other languages
English (en)
Inventor
Akihito Saitoh
Yoshiaki Suzuki
Kenji Yonezawa
Mitsuhide Kawamura
Takahiko Kusanagi
Takashi Nakai
Original Assignee
Toyama Chemical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co., Ltd. filed Critical Toyama Chemical Co., Ltd.
Publication of CY1113571T1 publication Critical patent/CY1113571T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Η εφεύρεση παρέχει μία μέθοδο για την παραγωγή 1-(3-(2-(1-βενζοθειοφαιν-5-υλ)αιθοξυ)προπυλ)αζετιδιν-3-όλης ή αλάτων αυτής χαρακτηριζόμενη από υποβολή της 1-(3-(2-(1-βενζοθειοφαιν-5-υλ)αιθοξυ)προπιονυλ)αζετιδιν-3-όλης σε αντίδραση αναγωγής με την προσθήκη ενεργοποιητή παρουσία βοριοϋδριδίου αλκαλίου.
CY20131100075T 2005-03-28 2013-01-25 Μεθοδος για την παραγωγη 1-(3-(2-(1-βενζοθειοφαιν-5-υλ)-αιθοξυ)προπυλ)αζετιδιν-3-ολης ή αλατων αυτης CY1113571T1 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2005090831 2005-03-28
JP2005174738 2005-06-15
JP2005206808 2005-07-15
JP2005230666 2005-08-09
EP11002265A EP2348022B1 (en) 2005-03-28 2006-03-27 Process for production of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salts thereof

Publications (1)

Publication Number Publication Date
CY1113571T1 true CY1113571T1 (el) 2016-06-22

Family

ID=37053344

Family Applications (3)

Application Number Title Priority Date Filing Date
CY20121100434T CY1112956T1 (el) 2005-03-28 2012-05-08 Μεθοδος για την παραγωγη 1-(3-(2-(1-βενζοθειοφαιν-5-υλ)-αιθοξυ)προπιονικου οξεος ή αλατων αυτου
CY20121100566T CY1112885T1 (el) 2005-03-28 2012-06-27 Αλκυλ-3-[2-(βενζο[b]θειοφαιν-5-υλ)-αιθοξυ]-προπανοϊκα αλατα ως ενδιαμεσα στην παραγωγη παραγωγων αζετιδιν-3-ολης
CY20131100075T CY1113571T1 (el) 2005-03-28 2013-01-25 Μεθοδος για την παραγωγη 1-(3-(2-(1-βενζοθειοφαιν-5-υλ)-αιθοξυ)προπυλ)αζετιδιν-3-ολης ή αλατων αυτης

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CY20121100434T CY1112956T1 (el) 2005-03-28 2012-05-08 Μεθοδος για την παραγωγη 1-(3-(2-(1-βενζοθειοφαιν-5-υλ)-αιθοξυ)προπιονικου οξεος ή αλατων αυτου
CY20121100566T CY1112885T1 (el) 2005-03-28 2012-06-27 Αλκυλ-3-[2-(βενζο[b]θειοφαιν-5-υλ)-αιθοξυ]-προπανοϊκα αλατα ως ενδιαμεσα στην παραγωγη παραγωγων αζετιδιν-3-ολης

Country Status (22)

Country Link
US (2) US7951963B2 (el)
EP (4) EP2210884B1 (el)
JP (1) JP5031554B2 (el)
KR (2) KR101337382B1 (el)
CN (1) CN101151257B (el)
AT (2) ATE557020T1 (el)
AU (1) AU2006229271B2 (el)
BR (1) BRPI0609496C8 (el)
CA (2) CA2799659C (el)
CY (3) CY1112956T1 (el)
DK (2) DK2248809T3 (el)
ES (3) ES2384312T3 (el)
IL (2) IL186044A (el)
MX (1) MX2007011938A (el)
NO (3) NO340071B1 (el)
NZ (2) NZ561672A (el)
PL (3) PL2248809T3 (el)
PT (3) PT2210884E (el)
SG (1) SG155251A1 (el)
SI (3) SI2348022T1 (el)
WO (1) WO2006104088A1 (el)
ZA (1) ZA200708262B (el)

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Also Published As

Publication number Publication date
PT2348022E (pt) 2013-02-13
EP2248809B1 (en) 2012-05-09
EP2348022B1 (en) 2013-01-09
CA2799659A1 (en) 2006-10-05
EP1864978A4 (en) 2009-07-01
AU2006229271A1 (en) 2006-10-05
PT2248809E (pt) 2012-07-02
US20110098484A1 (en) 2011-04-28
EP2210884B1 (en) 2012-02-22
KR20080008334A (ko) 2008-01-23
BRPI0609496C8 (pt) 2021-05-25
NO20074618L (no) 2007-10-25
ATE546443T1 (de) 2012-03-15
CA2600381C (en) 2013-11-12
IL186044A (en) 2013-12-31
BRPI0609496C1 (pt) 2021-05-11
KR20130010090A (ko) 2013-01-25
ATE557020T1 (de) 2012-05-15
SI2210884T1 (sl) 2012-06-29
NO20161418A1 (no) 2007-10-25
PL2210884T3 (pl) 2012-07-31
CA2600381A1 (en) 2006-10-05
CN101151257A (zh) 2008-03-26
US20090069576A1 (en) 2009-03-12
EP2210884A3 (en) 2010-09-22
CA2799659C (en) 2014-12-02
WO2006104088A1 (ja) 2006-10-05
ES2380443T3 (es) 2012-05-11
EP2210884A2 (en) 2010-07-28
ES2398934T3 (es) 2013-03-22
NO340420B1 (no) 2017-04-18
CN101151257B (zh) 2012-07-18
BRPI0609496B1 (pt) 2020-11-24
PL2248809T3 (pl) 2012-10-31
EP2248809A1 (en) 2010-11-10
EP2348022A1 (en) 2011-07-27
AU2006229271B2 (en) 2012-02-09
JPWO2006104088A1 (ja) 2008-09-04
JP5031554B2 (ja) 2012-09-19
NO340071B1 (no) 2017-03-06
KR101337382B1 (ko) 2013-12-06
NZ561672A (en) 2010-04-30
NZ583580A (en) 2010-10-29
KR101283930B1 (ko) 2013-07-16
NO340366B1 (no) 2017-04-10
EP1864978A1 (en) 2007-12-12
IL186044A0 (en) 2008-02-09
SI2348022T1 (sl) 2013-05-31
MX2007011938A (es) 2008-03-14
PL2348022T3 (pl) 2013-06-28
US7951963B2 (en) 2011-05-31
SI2248809T1 (sl) 2012-09-28
NO20161419A1 (no) 2016-06-07
ZA200708262B (en) 2009-01-28
BRPI0609496A2 (pt) 2011-10-18
DK2210884T3 (da) 2012-03-26
PT2210884E (pt) 2012-04-10
CY1112885T1 (el) 2016-04-13
ES2384312T3 (es) 2012-07-03
US8273902B2 (en) 2012-09-25
IL214245A (en) 2014-12-31
SG155251A1 (en) 2009-09-30
DK2248809T3 (da) 2012-06-18
CY1112956T1 (el) 2016-04-13
IL214245A0 (en) 2011-08-31

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