DK175582B1 - Anvendelse af en 17-ketosteroid forbindelse til brug ved profylakse og behandling af retroviral infektion - Google Patents

Anvendelse af en 17-ketosteroid forbindelse til brug ved profylakse og behandling af retroviral infektion Download PDF

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Publication number
DK175582B1
DK175582B1 DK198802081A DK208188A DK175582B1 DK 175582 B1 DK175582 B1 DK 175582B1 DK 198802081 A DK198802081 A DK 198802081A DK 208188 A DK208188 A DK 208188A DK 175582 B1 DK175582 B1 DK 175582B1
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DK
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Prior art keywords
compound
hiv
cells
infection
prophylaxis
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DK198802081A
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Danish (da)
English (en)
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DK208188D0 (da
DK208188A (da
Inventor
Patrick Thomas Prendergast
Original Assignee
Patrick Thomas Prendergast
Colthurst Ltd
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Publication date
Application filed by Patrick Thomas Prendergast, Colthurst Ltd filed Critical Patrick Thomas Prendergast
Publication of DK208188D0 publication Critical patent/DK208188D0/da
Publication of DK208188A publication Critical patent/DK208188A/da
Application granted granted Critical
Publication of DK175582B1 publication Critical patent/DK175582B1/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK198802081A 1987-04-16 1988-04-15 Anvendelse af en 17-ketosteroid forbindelse til brug ved profylakse og behandling af retroviral infektion DK175582B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IE99787 1987-04-16
IE99787 1987-04-16
IE228987 1987-08-27
IE228987 1987-08-27

Publications (3)

Publication Number Publication Date
DK208188D0 DK208188D0 (da) 1988-04-15
DK208188A DK208188A (da) 1988-10-17
DK175582B1 true DK175582B1 (da) 2004-12-13

Family

ID=26319024

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198802081A DK175582B1 (da) 1987-04-16 1988-04-15 Anvendelse af en 17-ketosteroid forbindelse til brug ved profylakse og behandling af retroviral infektion

Country Status (23)

Country Link
US (1) US4956355A (nl)
JP (1) JP2577771B2 (nl)
KR (1) KR960014988B1 (nl)
AT (1) AT401470B (nl)
AU (1) AU608824B2 (nl)
BE (1) BE1004315A5 (nl)
CA (1) CA1325594C (nl)
CH (1) CH675358A5 (nl)
DE (1) DE3812595C2 (nl)
DK (1) DK175582B1 (nl)
FI (1) FI881773A (nl)
FR (1) FR2615394B1 (nl)
GB (1) GB2204237B (nl)
GR (1) GR1002240B (nl)
IL (1) IL86089A (nl)
IT (1) IT1227073B (nl)
LU (1) LU87202A1 (nl)
NL (1) NL194728C (nl)
NZ (1) NZ224272A (nl)
OA (1) OA08729A (nl)
PH (1) PH25907A (nl)
PT (1) PT87259B (nl)
SE (1) SE503482C2 (nl)

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US5356900A (en) * 1986-10-07 1994-10-18 Bernard Bihari Method of treating chronic herpes virus infections using an opiate receptor antagonist
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US5204113A (en) * 1987-04-09 1993-04-20 Fisons Plc Pharmaceutical compositions containing pentamidine
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US5077284A (en) * 1988-12-30 1991-12-31 Loria Roger M Use of dehydroepiandrosterone to improve immune response
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US5562910A (en) * 1989-09-25 1996-10-08 University Of Utah Research Foundation Vaccine compositions and method for enhancing an immune response
US5824313A (en) * 1989-09-25 1998-10-20 University Of Utah Research Foundation Vaccine compositions and method for induction of mucosal immune response via systemic vaccination
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US5837269A (en) * 1989-09-25 1998-11-17 University Of Utah Research Foundation Vaccine compositions and method for enhancing an immune response
US5518725A (en) * 1989-09-25 1996-05-21 University Of Utah Research Foundation Vaccine compositions and method for induction of mucosal immune response via systemic vaccination
US5753237A (en) * 1989-09-25 1998-05-19 University Of Utah Research Foundation Method for augmenting immunological responses
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US5292730A (en) * 1990-08-29 1994-03-08 Humanetics Corporation Modulation of immune system with Δ5-androstenes
IE63418B1 (en) * 1990-09-10 1995-04-19 Elan Corp Plc Progression risk of HIV by assay of dehydroepiandrosterone in body fluid
US5206008A (en) * 1991-04-15 1993-04-27 Virginia Commonwealth University Enhancement of immune response
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FR2696934B1 (fr) * 1992-10-20 1995-06-02 Conservatoire Nal Arts Metiers Dérivés de stéroïdes naturels 3B hydroxyles ayant des propriétés de déclenchement et de stimulation de l'immunité, composition les contenant et procédé pour les obtenir.
US5776923A (en) * 1993-01-19 1998-07-07 Endorecherche, Inc. Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone
ATE275957T1 (de) * 1993-01-19 2004-10-15 Endorech Inc Therapeutische verwendungen und verabreichungsysteme von dehydroepiandrosteron
US5439899A (en) * 1993-03-10 1995-08-08 Purdue Research Foundation Cosalane and related compounds having activity against aids and aids-related infections
US5407927A (en) * 1993-04-16 1995-04-18 The Regents Of The University Of California Treatment of mild depression and restoration of IGF-I levels in aging by dehydroepiandrosterone
US5466465A (en) * 1993-12-30 1995-11-14 Harrogate Holdings, Limited Transdermal drug delivery system
AU701529B2 (en) * 1994-04-05 1999-01-28 Purdue Research Foundation NADH oxidase as a target in diagnosis and therapy
US5660835A (en) * 1995-02-24 1997-08-26 East Carolina University Method of treating adenosine depletion
US20020032160A1 (en) * 1995-02-24 2002-03-14 Nyce Jonathan W. Compositions & formulations with an epiandrosterone or a ubiquinone & kits & their use for treatment of asthma symptoms & for reducing adenosine/adenosine receptor levels
US7893044B2 (en) * 1995-02-24 2011-02-22 Epigenesis Pharmaceutical, Inc. Composition and method for altering levels of or sensitivity to adenosine with analogs of dehydroepiandrosterone
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US5922335A (en) * 1995-05-15 1999-07-13 Avon Products, Inc. Uses for ascorbyl-phosphoryl-cholesterol in topical compositions
US5736537A (en) 1995-09-12 1998-04-07 Estee Lauder, Inc. Dehydroep:androsterone sailcylate useful against skin atrophy
DE69605556T2 (de) * 1996-05-14 2000-06-15 Avon Prod Inc Ascorbyl-phosphorylcholesterol
GB9612990D0 (en) * 1996-06-20 1996-08-21 Stanford Rock Ltd Compositions and methods for the treatment of chronic infections
US5885977A (en) * 1997-01-15 1999-03-23 Humanetics Corporation Use of Δ5 androstenes in the treatment of HIV wasting syndrome
US5902593A (en) * 1997-10-01 1999-05-11 Kent; Frances B. Topically applied personal lubricant containing benzalkonium chloride as the active ingredient
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
US20060079492A1 (en) * 1999-10-25 2006-04-13 Ahlem Clarence N Compositions and treatment methods
US6667299B1 (en) 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
CN1328463A (zh) * 1998-11-24 2001-12-26 霍利斯-伊登医药公司 17-酮甾类化合物及其衍生物、代谢产物和前体在治疗丙型肝炎病毒和其他披膜病毒中的应用
US20070129282A1 (en) * 1998-11-24 2007-06-07 Ahlem Clarence N Pharmaceutical treatments and compositions
AP1584A (en) * 1998-11-24 2006-03-01 Hollis Eden Pharmaceuticals Inc Use of 17-ketosteroid compounds and derivatives, metabolites and precursors thereof in the treatment of malaria and the treatment of African and American trypanosomiasis.
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EP1422234A3 (en) * 1999-03-23 2010-12-08 Harbor BioSciences, Inc. Immunomodulatory steroids, in particular the hemihydrate of 16.alpha.-bromoepiandrosterone
RU2417792C2 (ru) * 1999-03-23 2011-05-10 Харбор Биосайенсиз, Инк. Иммуномодуляторные стероиды
FR2792201B1 (fr) * 1999-04-15 2001-11-02 Donatien Mavoungou Procede du renforcement immunitaire et du developpement d'un transporteur lipidique pour une therapie genique anti-vih et anti-bacterienne
US20050245502A1 (en) * 1999-08-23 2005-11-03 Phoenix Biosciences Treatments for viral infections
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US20050026890A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an antihistamine for treatment of asthma or chronic obstructive pulmonary disease
US20050026881A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anti-IgE antibody for treatment of asthma or chronic obstructive pulmonary disease
US20090317476A1 (en) * 2003-07-31 2009-12-24 Robinson Cynthia B Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
US20090297611A1 (en) * 2003-07-31 2009-12-03 Robinson Cynthia B Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a tyrosine kinase inhibitor, delta opioid receptor antagonist, neurokinin receptor antagonist, or vcam inhibitor for treatment of asthma or chronic obstructive pulmonary disease
US20050026882A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
US20050026879A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a tyrosine kinase inhibitor, delta opioid receptor antagonist, neurokinin receptor antagonist, or VCAM inhibitor for treatment of asthma or chronic obstructive pulmonary disease
US20090263381A1 (en) * 2003-07-31 2009-10-22 Robinson Cynthia B Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anti-ige antibody for treatment of asthma or chronic obstructive pulmonary disease
US20050026880A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a cromone for treatment of asthma or chronic obstructive pulmonary disease
US20090285899A1 (en) * 2003-07-31 2009-11-19 Robinson Cynthia B Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a methylxanthine derivative for treatment of asthma or chronic obstructive pulmonary disease
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US20050113318A1 (en) * 2003-07-31 2005-05-26 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a beta-agonist bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
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Also Published As

Publication number Publication date
GB2204237B (en) 1991-02-06
BE1004315A5 (fr) 1992-11-03
DE3812595C2 (de) 1997-07-03
DK208188D0 (da) 1988-04-15
FR2615394A1 (fr) 1988-11-25
AT401470B (de) 1996-09-25
IL86089A (en) 1992-11-15
PH25907A (en) 1991-12-19
IT8847858A0 (it) 1988-04-15
FI881773A0 (fi) 1988-04-15
CA1325594C (en) 1993-12-28
DE3812595A1 (de) 1988-10-27
ATA98488A (de) 1996-02-15
KR880012233A (ko) 1988-11-26
NL194728B (nl) 2002-09-02
PT87259B (pt) 1992-08-31
AU1467888A (en) 1988-10-20
NL8800926A (nl) 1988-11-16
GR1002240B (en) 1996-04-22
DK208188A (da) 1988-10-17
SE8801406D0 (sv) 1988-04-15
NL194728C (nl) 2003-01-07
FI881773A (fi) 1988-10-17
PT87259A (pt) 1988-05-01
GB8808864D0 (en) 1988-05-18
IL86089A0 (en) 1988-09-30
JPS6425722A (en) 1989-01-27
GR880100248A (el) 1989-01-31
LU87202A1 (fr) 1988-11-17
US4956355A (en) 1990-09-11
FR2615394B1 (fr) 1994-09-23
JP2577771B2 (ja) 1997-02-05
SE503482C2 (sv) 1996-06-24
NZ224272A (en) 1991-09-25
SE8801406L (sv) 1988-10-17
CH675358A5 (nl) 1990-09-28
GB2204237A (en) 1988-11-09
IT1227073B (it) 1991-03-14
OA08729A (en) 1989-03-31
AU608824B2 (en) 1991-04-18
KR960014988B1 (ko) 1996-10-23

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