DK1732921T3 - Thiomidderivater som progesteronreceptormodulatorer - Google Patents
Thiomidderivater som progesteronreceptormodulatorerInfo
- Publication number
- DK1732921T3 DK1732921T3 DK05735464T DK05735464T DK1732921T3 DK 1732921 T3 DK1732921 T3 DK 1732921T3 DK 05735464 T DK05735464 T DK 05735464T DK 05735464 T DK05735464 T DK 05735464T DK 1732921 T3 DK1732921 T3 DK 1732921T3
- Authority
- DK
- Denmark
- Prior art keywords
- receptor modulators
- thiomide
- derivatives
- progesterone receptor
- thioamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Gynecology & Obstetrics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Ink Jet (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56056904P | 2004-04-08 | 2004-04-08 | |
PCT/US2005/011757 WO2005100346A1 (en) | 2004-04-08 | 2005-04-07 | Thioamide derivatives as progesterone receptor modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1732921T3 true DK1732921T3 (da) | 2009-02-23 |
Family
ID=34965700
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK05735464T DK1732921T3 (da) | 2004-04-08 | 2005-04-07 | Thiomidderivater som progesteronreceptormodulatorer |
Country Status (14)
Country | Link |
---|---|
US (4) | US7358246B2 (ja) |
EP (1) | EP1732921B1 (ja) |
JP (1) | JP4869221B2 (ja) |
CN (1) | CN100522960C (ja) |
AT (1) | ATE413398T1 (ja) |
AU (1) | AU2005233591B2 (ja) |
BR (1) | BRPI0509209A (ja) |
CA (1) | CA2561014C (ja) |
DE (1) | DE602005010840D1 (ja) |
DK (1) | DK1732921T3 (ja) |
ES (1) | ES2317223T3 (ja) |
MX (1) | MXPA06011696A (ja) |
PL (1) | PL1732921T3 (ja) |
WO (1) | WO2005100346A1 (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE409699T1 (de) * | 2004-04-08 | 2008-10-15 | Wyeth Corp | Verfahren zur minimierung von thioamidverunreinigungen |
WO2005100346A1 (en) * | 2004-04-08 | 2005-10-27 | Wyeth | Thioamide derivatives as progesterone receptor modulators |
GT200500185A (es) * | 2004-08-09 | 2006-04-10 | Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos | |
US20070093548A1 (en) * | 2005-10-25 | 2007-04-26 | Wyeth | Use of progesterone receptor modulators |
US7618989B2 (en) * | 2006-08-15 | 2009-11-17 | Wyeth | Tricyclic oxazolidone derivatives useful as PR modulators |
AU2008341138A1 (en) * | 2007-12-20 | 2009-07-02 | Teva Women's Health, Inc. | Dosage regimens and pharmaceutical compositions and packages for emergency contraception |
CN107281215A (zh) * | 2016-04-01 | 2017-10-24 | 复旦大学附属妇产科医院 | 硫化氢供体硫氢化钠在制药中的用途 |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3536809A (en) * | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
US3598123A (en) * | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
US3845770A (en) * | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3916899A (en) * | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
US4008719A (en) * | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
US4295987A (en) * | 1979-12-26 | 1981-10-20 | The Procter & Gamble Company | Cross-linked sodium polyacrylate absorbent |
US4959217A (en) * | 1986-05-22 | 1990-09-25 | Syntex (U.S.A.) Inc. | Delayed/sustained release of macromolecules |
AU608891B2 (en) | 1987-09-24 | 1991-04-18 | Merck & Co., Inc. | Solubility modulated drug delivery device |
US5273752A (en) * | 1989-07-18 | 1993-12-28 | Alza Corporation | Controlled release dispenser comprising beneficial agent |
US5124455A (en) * | 1990-08-08 | 1992-06-23 | American Home Products Corporation | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents |
US5459151A (en) * | 1993-04-30 | 1995-10-17 | American Home Products Corporation | N-acyl substituted phenyl piperidines as bronchodilators and antiinflammatory agents |
US5854388A (en) * | 1993-06-24 | 1998-12-29 | Washington State University Research Foundation | Angiotensin IV peptides and receptor |
US5817343A (en) * | 1996-05-14 | 1998-10-06 | Alkermes, Inc. | Method for fabricating polymer-based controlled-release devices |
US5756127A (en) * | 1996-10-29 | 1998-05-26 | Wright Medical Technology, Inc. | Implantable bioresorbable string of calcium sulfate beads |
FI971385A0 (fi) | 1997-04-04 | 1997-04-04 | Bioxid Oy | Biokompatibel komposition, metoder foer dess framstaellning samt anvaendning daerav |
US6509334B1 (en) * | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
CN1143847C (zh) * | 1999-05-04 | 2004-03-31 | 美国家庭用品有限公司 | 硫代-羟吲哚衍生物 |
US6417214B1 (en) * | 1999-05-04 | 2002-07-09 | Wyeth | 3,3-substituted indoline derivatives |
US6355648B1 (en) * | 1999-05-04 | 2002-03-12 | American Home Products Corporation | Thio-oxindole derivatives |
US6391907B1 (en) * | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
HUP0203332A3 (en) * | 1999-05-04 | 2004-12-28 | Wyeth Corp | Cyclothiocarbamate derivatives, their use as progesterone receptor modulators and pharmaceutical compositions containing them |
US6407101B1 (en) * | 1999-05-04 | 2002-06-18 | American Home Products Corporation | Cyanopyrroles |
CN1368952A (zh) * | 1999-08-10 | 2002-09-11 | 史密丝克莱恩比彻姆公司 | 1,4-取代的4,4-二芳基环己烷 |
US6258833B1 (en) * | 1999-12-23 | 2001-07-10 | Icos Corporation | Cyclic AMP-specific phosphodiesterase inhibitors |
UA73119C2 (en) | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
JP4716547B2 (ja) * | 2000-08-10 | 2011-07-06 | 住友精化株式会社 | 2−フェニルチアゾール類の製造方法 |
US20030225273A1 (en) * | 2002-03-21 | 2003-12-04 | Michaelides Michael R. | Thiopyrimidine and isothiazolopyrimidine kinase inhibitors |
EP1514552A4 (en) * | 2002-06-06 | 2008-04-02 | Eisai R&D Man Co Ltd | NEW MILED IMIDAZOLE DERIVATIVE |
RU2005101638A (ru) * | 2002-06-25 | 2006-01-20 | Уайт (Us) | Использование циклокарбаматных производных для лечения гормонзависимых состояний |
RU2005101624A (ru) | 2002-06-25 | 2005-06-27 | Уайт (Us) | Применение производных тиооксиндола в терапии кожных нарушений |
AU2003245657A1 (en) | 2002-06-25 | 2004-01-06 | Wyeth | Cyclothiocarbamative derivatives as pr modulators and use thereof for treatment of skin disorders |
CA2489813A1 (en) | 2002-06-25 | 2003-12-31 | Wyeth | Use of thio-oxindole derivatives in treatment of hormone-related conditions |
CA2561047C (en) * | 2004-04-08 | 2013-07-16 | Wyeth | Method for preparing 3-cyclopentyloxy-4-methoxybenzaldehyde |
WO2005100346A1 (en) * | 2004-04-08 | 2005-10-27 | Wyeth | Thioamide derivatives as progesterone receptor modulators |
ATE409699T1 (de) * | 2004-04-08 | 2008-10-15 | Wyeth Corp | Verfahren zur minimierung von thioamidverunreinigungen |
AU2005237520B2 (en) * | 2004-04-27 | 2012-01-19 | Wyeth | Purification of progesterone receptor modulators |
-
2005
- 2005-04-07 WO PCT/US2005/011757 patent/WO2005100346A1/en active Application Filing
- 2005-04-07 CN CNB2005800108301A patent/CN100522960C/zh not_active Expired - Fee Related
- 2005-04-07 AT AT05735464T patent/ATE413398T1/de not_active IP Right Cessation
- 2005-04-07 DK DK05735464T patent/DK1732921T3/da active
- 2005-04-07 EP EP05735464A patent/EP1732921B1/en not_active Not-in-force
- 2005-04-07 JP JP2007507494A patent/JP4869221B2/ja not_active Expired - Fee Related
- 2005-04-07 PL PL05735464T patent/PL1732921T3/pl unknown
- 2005-04-07 AU AU2005233591A patent/AU2005233591B2/en not_active Ceased
- 2005-04-07 CA CA2561014A patent/CA2561014C/en not_active Expired - Fee Related
- 2005-04-07 US US11/100,860 patent/US7358246B2/en not_active Expired - Fee Related
- 2005-04-07 BR BRPI0509209-4A patent/BRPI0509209A/pt not_active IP Right Cessation
- 2005-04-07 ES ES05735464T patent/ES2317223T3/es active Active
- 2005-04-07 DE DE602005010840T patent/DE602005010840D1/de active Active
- 2005-04-07 MX MXPA06011696A patent/MXPA06011696A/es active IP Right Grant
-
2008
- 2008-03-07 US US12/044,287 patent/US7511071B2/en not_active Expired - Fee Related
-
2009
- 2009-02-12 US US12/369,789 patent/US7659265B2/en not_active Expired - Fee Related
-
2010
- 2010-02-02 US US12/698,472 patent/US8168672B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1732921B1 (en) | 2008-11-05 |
PL1732921T3 (pl) | 2009-04-30 |
US7511071B2 (en) | 2009-03-31 |
JP4869221B2 (ja) | 2012-02-08 |
CA2561014A1 (en) | 2005-10-27 |
AU2005233591B2 (en) | 2011-10-27 |
JP2007532564A (ja) | 2007-11-15 |
ATE413398T1 (de) | 2008-11-15 |
EP1732921A1 (en) | 2006-12-20 |
DE602005010840D1 (de) | 2008-12-18 |
AU2005233591A1 (en) | 2005-10-27 |
MXPA06011696A (es) | 2006-12-14 |
US20080167299A1 (en) | 2008-07-10 |
US20050227971A1 (en) | 2005-10-13 |
CA2561014C (en) | 2013-09-10 |
BRPI0509209A (pt) | 2007-08-28 |
US20100197645A1 (en) | 2010-08-05 |
US8168672B2 (en) | 2012-05-01 |
WO2005100346A1 (en) | 2005-10-27 |
US7358246B2 (en) | 2008-04-15 |
US7659265B2 (en) | 2010-02-09 |
CN1938299A (zh) | 2007-03-28 |
US20090143345A1 (en) | 2009-06-04 |
CN100522960C (zh) | 2009-08-05 |
ES2317223T3 (es) | 2009-04-16 |
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