ATE409699T1 - Verfahren zur minimierung von thioamidverunreinigungen - Google Patents
Verfahren zur minimierung von thioamidverunreinigungenInfo
- Publication number
- ATE409699T1 ATE409699T1 AT05738187T AT05738187T ATE409699T1 AT E409699 T1 ATE409699 T1 AT E409699T1 AT 05738187 T AT05738187 T AT 05738187T AT 05738187 T AT05738187 T AT 05738187T AT E409699 T1 ATE409699 T1 AT E409699T1
- Authority
- AT
- Austria
- Prior art keywords
- minimizing
- thioamide
- pollution
- thionations
- products
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- AEOCXXJPGCBFJA-UHFFFAOYSA-N ethionamide Chemical compound CCC1=CC(C(N)=S)=CC=N1 AEOCXXJPGCBFJA-UHFFFAOYSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001728 carbonyl compounds Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 125000002560 nitrile group Chemical group 0.000 abstract 1
- 150000003556 thioamides Chemical class 0.000 abstract 1
- 238000007280 thionation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Glass Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56040304P | 2004-04-08 | 2004-04-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE409699T1 true ATE409699T1 (de) | 2008-10-15 |
Family
ID=34966434
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05738187T ATE409699T1 (de) | 2004-04-08 | 2005-04-07 | Verfahren zur minimierung von thioamidverunreinigungen |
Country Status (14)
Country | Link |
---|---|
US (2) | US7314932B2 (de) |
EP (1) | EP1732922B1 (de) |
JP (1) | JP4950027B2 (de) |
CN (1) | CN1938298B (de) |
AT (1) | ATE409699T1 (de) |
AU (1) | AU2005233648B2 (de) |
BR (1) | BRPI0509213A (de) |
CA (1) | CA2561313C (de) |
DE (1) | DE602005010065D1 (de) |
DK (1) | DK1732922T3 (de) |
ES (1) | ES2313334T3 (de) |
MX (1) | MXPA06011695A (de) |
PL (1) | PL1732922T3 (de) |
WO (1) | WO2005100347A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005100347A1 (en) | 2004-04-08 | 2005-10-27 | Wyeth | Methods for minimizing thioamide impurities |
CN100522960C (zh) * | 2004-04-08 | 2009-08-05 | 惠氏公司 | 作为***受体调节剂的硫代酰胺衍生物 |
JP2011507853A (ja) * | 2007-12-20 | 2011-03-10 | テバ ウィメンズ ヘルス インコーポレイテッド | 緊急避妊のための投与量レジメンならびに薬学的組成物およびパッケージ |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8308064D0 (en) * | 1983-03-24 | 1983-05-05 | Beecham Group Plc | Active compounds |
US4997950A (en) * | 1989-04-20 | 1991-03-05 | Richard Finbar Murphy | Novel C-terminal gastrin antagonists |
JPH0834775A (ja) * | 1994-05-16 | 1996-02-06 | Sumitomo Chem Co Ltd | テトラゾール化合物の製造法 |
EA004511B1 (ru) * | 1999-05-04 | 2004-04-29 | Америкэн Хоум Продактс Корпорейшн | Циклотиокарбаматные производные в качестве модуляторов рецептора прогестерона |
US6391907B1 (en) * | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
US6509334B1 (en) * | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
US6417214B1 (en) * | 1999-05-04 | 2002-07-09 | Wyeth | 3,3-substituted indoline derivatives |
MXPA01011285A (es) * | 1999-05-04 | 2003-09-04 | American Home Prod | Derivados de tio-oxindol. |
US6407101B1 (en) * | 1999-05-04 | 2002-06-18 | American Home Products Corporation | Cyanopyrroles |
UA73119C2 (en) * | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
US7132445B2 (en) * | 2001-04-16 | 2006-11-07 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
AR040644A1 (es) * | 2002-06-25 | 2005-04-13 | Wyeth Corp | Un moduladores del receptor de progesterona benzoxazina-2-tiona, una composicion farmaceutica, uso del compuesto para preparar un dedicamento para tratar una enfermedad neoplasica-hormona-dependiente y el uso de un compuesto benzoxazina-2-tiona, benzoxazina-2-ilideno cianamida o benzoxazina-2-iliden |
AU2003245637A1 (en) * | 2002-06-25 | 2004-01-06 | Wyeth | Use of thio-oxindole derivatives in treatment of hormone-related conditions |
JP2005535625A (ja) * | 2002-06-25 | 2005-11-24 | ワイス | 皮膚障害の治療におけるチオオキシインドール誘導体の使用 |
WO2004000801A2 (en) * | 2002-06-25 | 2003-12-31 | Wyeth | Use of cyclothiocarbamate derivatives in treatment of hormone-related conditions |
WO2005100347A1 (en) | 2004-04-08 | 2005-10-27 | Wyeth | Methods for minimizing thioamide impurities |
CN100522960C (zh) * | 2004-04-08 | 2009-08-05 | 惠氏公司 | 作为***受体调节剂的硫代酰胺衍生物 |
-
2005
- 2005-04-07 WO PCT/US2005/013657 patent/WO2005100347A1/en not_active Application Discontinuation
- 2005-04-07 MX MXPA06011695A patent/MXPA06011695A/es active IP Right Grant
- 2005-04-07 AT AT05738187T patent/ATE409699T1/de not_active IP Right Cessation
- 2005-04-07 BR BRPI0509213-2A patent/BRPI0509213A/pt not_active IP Right Cessation
- 2005-04-07 PL PL05738187T patent/PL1732922T3/pl unknown
- 2005-04-07 JP JP2007507577A patent/JP4950027B2/ja not_active Expired - Fee Related
- 2005-04-07 DK DK05738187T patent/DK1732922T3/da active
- 2005-04-07 CN CN2005800102930A patent/CN1938298B/zh not_active Expired - Fee Related
- 2005-04-07 ES ES05738187T patent/ES2313334T3/es active Active
- 2005-04-07 US US11/100,863 patent/US7314932B2/en not_active Expired - Fee Related
- 2005-04-07 DE DE602005010065T patent/DE602005010065D1/de active Active
- 2005-04-07 AU AU2005233648A patent/AU2005233648B2/en not_active Ceased
- 2005-04-07 EP EP05738187A patent/EP1732922B1/de not_active Not-in-force
- 2005-04-07 CA CA2561313A patent/CA2561313C/en not_active Expired - Fee Related
-
2007
- 2007-11-16 US US11/985,774 patent/US7572824B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20080071083A1 (en) | 2008-03-20 |
JP4950027B2 (ja) | 2012-06-13 |
CN1938298B (zh) | 2013-02-06 |
PL1732922T3 (pl) | 2009-03-31 |
US7572824B2 (en) | 2009-08-11 |
US7314932B2 (en) | 2008-01-01 |
DK1732922T3 (da) | 2009-01-12 |
CA2561313A1 (en) | 2005-10-27 |
JP2007532581A (ja) | 2007-11-15 |
CN1938298A (zh) | 2007-03-28 |
CA2561313C (en) | 2012-12-04 |
EP1732922A1 (de) | 2006-12-20 |
AU2005233648B2 (en) | 2011-06-23 |
WO2005100347A1 (en) | 2005-10-27 |
BRPI0509213A (pt) | 2007-08-28 |
ES2313334T3 (es) | 2009-03-01 |
MXPA06011695A (es) | 2006-12-14 |
DE602005010065D1 (de) | 2008-11-13 |
EP1732922B1 (de) | 2008-10-01 |
AU2005233648A1 (en) | 2005-10-27 |
US20050228179A1 (en) | 2005-10-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |