DK172236B1 - Lægemiddel indeholdende dipyridamol eller mopidamol og o-acetylsalicylsyre eller fysiologisk acceptable salte deraf - Google Patents

Lægemiddel indeholdende dipyridamol eller mopidamol og o-acetylsalicylsyre eller fysiologisk acceptable salte deraf Download PDF

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Publication number
DK172236B1
DK172236B1 DK421187A DK421187A DK172236B1 DK 172236 B1 DK172236 B1 DK 172236B1 DK 421187 A DK421187 A DK 421187A DK 421187 A DK421187 A DK 421187A DK 172236 B1 DK172236 B1 DK 172236B1
Authority
DK
Denmark
Prior art keywords
acetylsalicylic acid
dipyridamole
acceptable salts
physiologically acceptable
mopidamole
Prior art date
Application number
DK421187A
Other languages
Danish (da)
English (en)
Other versions
DK421187D0 (da
DK421187A (da
Inventor
Wolfgang Eisert
Peter Gruber
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6307286&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK172236(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK421187D0 publication Critical patent/DK421187D0/da
Publication of DK421187A publication Critical patent/DK421187A/da
Application granted granted Critical
Publication of DK172236B1 publication Critical patent/DK172236B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK421187A 1986-08-13 1987-08-12 Lægemiddel indeholdende dipyridamol eller mopidamol og o-acetylsalicylsyre eller fysiologisk acceptable salte deraf DK172236B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3627423 1986-08-13
DE19863627423 DE3627423A1 (de) 1986-08-13 1986-08-13 Arzneimittel enthaltend dipyridamol oder mopidamol und o-acetylsalicylsaeure bzw. deren physiologisch vertraegliche salze, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung der thrombusbildung

Publications (3)

Publication Number Publication Date
DK421187D0 DK421187D0 (da) 1987-08-12
DK421187A DK421187A (da) 1988-02-14
DK172236B1 true DK172236B1 (da) 1998-02-02

Family

ID=6307286

Family Applications (1)

Application Number Title Priority Date Filing Date
DK421187A DK172236B1 (da) 1986-08-13 1987-08-12 Lægemiddel indeholdende dipyridamol eller mopidamol og o-acetylsalicylsyre eller fysiologisk acceptable salte deraf

Country Status (26)

Country Link
US (1) US6015577A (fr)
EP (1) EP0257344B1 (fr)
JP (1) JP2593879B2 (fr)
KR (1) KR950009098B1 (fr)
AT (1) ATE59961T1 (fr)
AU (1) AU603146B2 (fr)
BR (1) BR1100593A (fr)
CA (1) CA1302272C (fr)
CL (1) CL2004001252A1 (fr)
DD (1) DD263918A5 (fr)
DE (3) DE3627423A1 (fr)
DK (1) DK172236B1 (fr)
ES (1) ES2020974B3 (fr)
FI (1) FI873492A (fr)
GR (1) GR3001695T3 (fr)
HK (1) HK14494A (fr)
HU (1) HU202404B (fr)
IE (1) IE60862B1 (fr)
IL (1) IL83510A (fr)
NL (1) NL990001I2 (fr)
NO (2) NO175132C (fr)
NZ (1) NZ221424A (fr)
PH (1) PH27176A (fr)
PT (1) PT85525B (fr)
SG (1) SG122593G (fr)
ZA (1) ZA875947B (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19927689A1 (de) * 1999-06-17 2000-12-21 Gruenenthal Gmbh Orale Darreichungsformen zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac
EP1093814A1 (fr) * 1999-10-22 2001-04-25 Boehringer Ingelheim Pharma KG Utilisation du dipyridamole ou du mopidamol dans la fabrication d'un médicament pour le traitement et la prévention des troubles de la microcirculation dépendants de la fibrine
US7064130B2 (en) * 2001-04-20 2006-06-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Use of radical-scavenging compounds for treatment and prevention of NO-dependent microcirculation disorders
US20040058056A1 (en) * 2001-07-06 2004-03-25 Shigemasa Osaki Drug diffusion coatings, applications and methods
WO2003030823A2 (fr) * 2001-10-05 2003-04-17 Combinatorx, Incorporated Combinaisons permettant le traitement des troubles inflammatoires
TW200301135A (en) * 2001-12-27 2003-07-01 Otsuka Maryland Res Inst Inc Pharmaceutical compositions comprising a multifunctional phosphodiesterase inhibitor and an adenosine uptake inhibitor
US20030181488A1 (en) * 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof
DE10209982A1 (de) * 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Oral zu applizierende Darreichungsform für schwerlösliche basische Wirkstoffe
US7485322B2 (en) * 2002-12-24 2009-02-03 Lek Pharmaceuticals D.D. Modified release pharmaceutical composition
CA2515266A1 (fr) * 2003-02-07 2004-08-19 Boehringer Ingelheim International Gmbh Utilisation du dipyridamole ou mopidamole pour le traitement et la prevention de troubles dependant de mmp-9
DE10306179A1 (de) 2003-02-13 2004-08-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe
BRPI0409796A (pt) * 2003-04-24 2006-05-30 Boehringer Ingelheim Int uso de dipiridamol ou mopidamol para tratamento e prevenção de doenças tromboembolìticas e distúrbios provocados pela formação excessiva de trombina e/ou pela expressão elevada de receptores de trombina
US7041286B2 (en) * 2003-07-23 2006-05-09 Nerenberg Arnold P Composition for mitigating a pernicious thrombotic event
TW200517114A (en) * 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
WO2005113006A2 (fr) * 2004-05-13 2005-12-01 Boehringer Ingelheim International Gmbh Utilisation de dipyridamole pour le traitement de la resistance a des inhibiteurs plaquettaires
US9205054B2 (en) 2005-03-22 2015-12-08 Losan Pharma Gmbh Solubilized ibuprofen
BRPI0614870A2 (pt) * 2005-08-22 2011-04-19 Novartis Ag composições farmacêuticas
CA2640382C (fr) 2006-01-27 2015-12-29 Eurand, Inc Systeme d'administration de medicaments comprenant des medicaments faiblement basiques et des acides organiques
CN103211779B (zh) * 2006-01-27 2016-03-16 阿代尔制药股份有限公司 包含弱碱性选择性5-羟色胺5-ht3阻断剂和有机酸的药物递送***
EP1820506B1 (fr) * 2006-02-09 2008-03-26 Teva Pharmaceutical Industries Ltd. Compositions de dipyridamole à libération prolongée et leur procédé de préparation
WO2007139753A2 (fr) * 2006-05-22 2007-12-06 Combinatorx, Incorporated Méthodes et compositions pour le traitement de maladies ou d'affections associées à des taux accrus de protéine c réactive, d'interleukine 6 ou d'interféron gamma
ITRM20060460A1 (it) * 2006-08-31 2006-11-30 Univ Roma Uso di acido acetil salicilico in combinazione con inibitori dei canali mrp4 per il trattamento di pazienti resistenti a detto acido acetil salicilico
WO2008095263A1 (fr) * 2007-02-09 2008-08-14 Alphapharm Pty Ltd Forme pharmaceutique contenant deux ou davantage de principes actifs pharmaceutiques sous des formes physiques différentes
CA2737131A1 (fr) * 2007-09-19 2009-03-26 Zalicus Inc. Regimes therapeutiques pour le traitement de troubles immunoinflammatoires
CA2709561A1 (fr) * 2007-12-17 2009-06-25 Combinatorx, Incorporated Regimes therapeutiques pour le traitement de troubles immuno-inflammatoires
WO2009097156A1 (fr) * 2008-02-01 2009-08-06 Barr Laboratories, Inc. Capsules pharmaceutiques comprenant des granules de dipyridamole à libération prolongée
US8133506B2 (en) * 2008-03-12 2012-03-13 Aptalis Pharmatech, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
WO2009118321A1 (fr) * 2008-03-28 2009-10-01 Boehringer Ingelheim International Gmbh Procédé de production de granules d'acide
US20100080846A1 (en) * 2008-09-25 2010-04-01 Avshalom Ben-Menachem Dipyridamole and acetylsalicylic acid formulations and process for preparing same
US20110003005A1 (en) * 2009-07-06 2011-01-06 Gopi Venkatesh Methods of Treating PDNV and PONV with Extended Release Ondansetron Compositions
EP2361615A1 (fr) 2010-02-19 2011-08-31 Alfred E. Tiefenbacher GmbH & Co. KG Comprimé à libération prolongée de dipyridamole
JP2014517843A (ja) * 2011-05-24 2014-07-24 テバ ファーマシューティカル インダストリーズ リミティド 医薬組成物用の圧縮コア
CN103239724A (zh) * 2013-05-27 2013-08-14 成都自豪药业有限公司 抗血栓形成的联合用药物及其药物组合物
ES2974674T3 (es) * 2017-06-19 2024-07-01 Cleveland Clinic Found Tratamiento de enfermedades y promoción de la pérdida de peso inhibiendo la vía TMA/FMO3/TMAO

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2368280A1 (fr) * 1976-10-20 1978-05-19 Theramex Nouvelle composition therapeutique presentant une activite anti-agregante plaquettaire, et son procede de preparation
FR2368272A1 (fr) * 1976-10-20 1978-05-19 Theramex Compositions therapeutiques solides pour combattre l'agregation plaquettaire
LU77353A1 (fr) * 1977-05-16 1979-01-19
DE3000979A1 (de) * 1980-01-12 1981-07-23 Dr. Karl Thomae Gmbh, 7950 Biberach Neue dipyridamol-retardformen und verfahren zu ihrer herstellung
FR2513118A1 (fr) * 1981-09-18 1983-03-25 Rocador Sa Composition pharmaceutique a base de dipyridamol et de sel d'aluminium de l'acide acetylsalicylique pour combattre l'agregation plaquettaire
ATE50497T1 (de) * 1984-07-21 1990-03-15 Hoechst Ag Kombinationspraeparat aus pyrimido-pyrimidinen und o-acetylsalicylsaeure bzw. deren pharmakologisch vertraeglichen salzen und dessen verwendung.

Also Published As

Publication number Publication date
NZ221424A (en) 1989-11-28
US6015577A (en) 2000-01-18
HU202404B (en) 1991-03-28
FI873492A (fi) 1988-02-14
AU7679587A (en) 1988-02-18
BR1100593A (pt) 2002-04-02
SG122593G (en) 1994-06-10
AU603146B2 (en) 1990-11-08
DE10299015I2 (de) 2005-06-16
PT85525B (pt) 1990-06-29
PT85525A (de) 1987-09-01
KR880002529A (ko) 1988-05-09
DE10299015I1 (de) 2002-10-10
ZA875947B (en) 1989-04-26
NO175132C (no) 1994-09-07
JPS6348219A (ja) 1988-02-29
DE3767408D1 (de) 1991-02-21
JP2593879B2 (ja) 1997-03-26
NO175132B (no) 1994-05-30
DD263918A5 (de) 1989-01-18
IE872152L (en) 1988-02-13
CA1302272C (fr) 1992-06-02
FI873492A0 (fi) 1987-08-12
HUT44937A (en) 1988-05-30
EP0257344B1 (fr) 1991-01-16
HK14494A (en) 1994-03-04
ES2020974B3 (es) 1991-10-16
NO873370D0 (no) 1987-08-12
GR3001695T3 (en) 1992-11-23
DK421187D0 (da) 1987-08-12
NO873370L (no) 1988-02-15
DE3627423A1 (de) 1988-02-18
IL83510A (en) 1992-02-16
CL2004001252A1 (es) 2005-03-04
IL83510A0 (en) 1988-01-31
PH27176A (en) 1993-04-02
NO1999014I1 (no) 1999-07-01
DK421187A (da) 1988-02-14
IE60862B1 (en) 1994-08-24
KR950009098B1 (en) 1995-08-14
NL990001I1 (nl) 1999-03-01
NL990001I2 (nl) 2000-04-03
EP0257344A1 (fr) 1988-03-02
ATE59961T1 (de) 1991-02-15

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
CTFF Application for supplementary protection certificate (spc) filed

Free format text: CA 2001 00022, 20010711, EXPIRES: 20120709

PUP Patent expired