DK1604687T3 - Micellefremstilling indeholdende ringe vandopløseligt anticancermiddel og ny blokcopolymer - Google Patents

Micellefremstilling indeholdende ringe vandopløseligt anticancermiddel og ny blokcopolymer

Info

Publication number
DK1604687T3
DK1604687T3 DK04721673.4T DK04721673T DK1604687T3 DK 1604687 T3 DK1604687 T3 DK 1604687T3 DK 04721673 T DK04721673 T DK 04721673T DK 1604687 T3 DK1604687 T3 DK 1604687T3
Authority
DK
Denmark
Prior art keywords
anticancer agent
block copolymer
soluble anticancer
integer
low water
Prior art date
Application number
DK04721673.4T
Other languages
English (en)
Inventor
Kazuhisa Shimizu
Toshitaka Murata
Katsuhiko Sagawa
Original Assignee
Nippon Kayaku Kk
Nanocarrier Kabushiki Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Kayaku Kk, Nanocarrier Kabushiki Kaisha filed Critical Nippon Kayaku Kk
Application granted granted Critical
Publication of DK1604687T3 publication Critical patent/DK1604687T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyamides (AREA)
  • Peptides Or Proteins (AREA)
DK04721673.4T 2003-03-20 2004-03-18 Micellefremstilling indeholdende ringe vandopløseligt anticancermiddel og ny blokcopolymer DK1604687T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003077607 2003-03-20
PCT/JP2004/003647 WO2004082718A1 (ja) 2003-03-20 2004-03-18 難水溶性抗癌剤と新規ブロック共重合体を含むミセル調製物

Publications (1)

Publication Number Publication Date
DK1604687T3 true DK1604687T3 (da) 2010-11-15

Family

ID=33027953

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04721673.4T DK1604687T3 (da) 2003-03-20 2004-03-18 Micellefremstilling indeholdende ringe vandopløseligt anticancermiddel og ny blokcopolymer

Country Status (14)

Country Link
US (3) US20060099265A1 (da)
EP (1) EP1604687B1 (da)
JP (1) JP4757633B2 (da)
KR (1) KR101064901B1 (da)
CN (1) CN1761485B (da)
AT (1) ATE483476T1 (da)
AU (1) AU2004222439B2 (da)
CA (1) CA2518964C (da)
DE (1) DE602004029449D1 (da)
DK (1) DK1604687T3 (da)
ES (1) ES2351338T3 (da)
PL (1) PL1604687T3 (da)
RU (1) RU2324701C2 (da)
WO (1) WO2004082718A1 (da)

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JP5503872B2 (ja) 2006-11-06 2014-05-28 日本化薬株式会社 核酸系代謝拮抗剤の高分子誘導体
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DK2474306T3 (da) * 2009-08-31 2017-02-06 Nanocarrier Co Ltd Partikelsammensætning og farmaceutisk sammensætning, der indeholder samme
CN103221054A (zh) 2010-11-17 2013-07-24 日本化药株式会社 新的胞苷类代谢拮抗剂的高分子衍生物
RU2623426C2 (ru) * 2011-09-11 2017-06-26 Ниппон Каяку Кабусики Кайся Способ получения блок-сополимера
US10945997B2 (en) 2016-01-08 2021-03-16 Nippon Kayaku Kabushiki Kaisha Polymer derivative of macrolide immunosuppressant
CN109476841B (zh) 2016-07-30 2021-08-24 日本化药株式会社 新型高分子衍生物和使用其的新型高分子衍生物成像探针
CN109642024A (zh) 2016-08-02 2019-04-16 日本化药株式会社 主动靶向型高分子衍生物、包含该高分子衍生物的组合物以及它们的用途
WO2022008527A1 (en) 2020-07-06 2022-01-13 Rheinisch-Westfälische Technische Hochschule (Rwth) Aachen Polymeric micelles comprising glucuronide-prodrugs

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CN101977631A (zh) * 2008-03-18 2011-02-16 日本化药株式会社 生理活性物质的高分子量偶联物
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Also Published As

Publication number Publication date
AU2004222439A1 (en) 2004-09-30
US20140142167A1 (en) 2014-05-22
KR101064901B1 (ko) 2011-09-16
PL1604687T3 (pl) 2011-04-29
RU2005132309A (ru) 2006-04-10
EP1604687A1 (en) 2005-12-14
EP1604687A4 (en) 2009-03-18
ES2351338T3 (es) 2011-02-03
CN1761485A (zh) 2006-04-19
JPWO2004082718A1 (ja) 2006-06-22
DE602004029449D1 (de) 2010-11-18
RU2324701C2 (ru) 2008-05-20
EP1604687B1 (en) 2010-10-06
CA2518964A1 (en) 2004-09-30
KR20050107800A (ko) 2005-11-15
JP4757633B2 (ja) 2011-08-24
US20060099265A1 (en) 2006-05-11
WO2004082718A1 (ja) 2004-09-30
AU2004222439B2 (en) 2008-08-21
CN1761485B (zh) 2010-04-28
US7820759B2 (en) 2010-10-26
CA2518964C (en) 2011-09-13
US20090156742A1 (en) 2009-06-18
ATE483476T1 (de) 2010-10-15

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