DK1526134T3 - Triazolyltropanderivater som CCR5-modulatorer - Google Patents

Triazolyltropanderivater som CCR5-modulatorer

Info

Publication number: DK1526134T3
Authority: DK; Denmark
Prior art keywords: triazolyltropane; derivatives; ccr5 modulators; ccr5; modulators
Prior art date: 2000-05-26

Application number

DK04004193T

Other languages

English (en)

Inventor

Manoussos Perros

David Anthony Price

Blanda Luzia Christa Stammen

Anthony Wood

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-26

Filing date

2001-05-09

Publication date

2008-11-17

2000-05-26 Priority claimed from GB0014046A external-priority patent/GB0014046D0/en

2000-06-27 Priority claimed from GB0015835A external-priority patent/GB0015835D0/en

2001-05-09 Application filed by Pfizer filed Critical Pfizer

2008-11-17 Application granted granted Critical

2008-11-17 Publication of DK1526134T3 publication Critical patent/DK1526134T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
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- A—HUMAN NECESSITIES
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- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A61P37/02—Immunomodulators
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Virology (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Obesity (AREA)
Hematology (AREA)
Physical Education & Sports Medicine (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Molecular Biology (AREA)
Emergency Medicine (AREA)
AIDS & HIV (AREA)
Pain & Pain Management (AREA)
Reproductive Health (AREA)
Psychiatry (AREA)
Transplantation (AREA)

DK04004193T 2000-05-26 2001-05-09 Triazolyltropanderivater som CCR5-modulatorer DK1526134T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB0014046A GB0014046D0 (en)	2000-05-26	2000-05-26	Compounds useful in therapy
GB0015835A GB0015835D0 (en)	2000-06-27	2000-06-27	Compounds useful in therapy
PCT/IB2001/000806 WO2001090106A2 (en)	2000-05-26	2001-05-09	Tryasolyl tropane derivatives as ccr5 modulators

Publications (1)

Publication Number	Publication Date
DK1526134T3 true DK1526134T3 (da)	2008-11-17

Family

ID=26244452

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK01925808T DK1284974T3 (da)	2000-05-26	2001-05-09	Triazolyltropanderivater som CCR5-modulatorer
DK04004193T DK1526134T3 (da)	2000-05-26	2001-05-09	Triazolyltropanderivater som CCR5-modulatorer

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK01925808T DK1284974T3 (da)	2000-05-26	2001-05-09	Triazolyltropanderivater som CCR5-modulatorer

Country Status (51)

Country	Link
EP (3)	EP1526134B1 (da)
JP (2)	JP3693957B2 (da)
KR (2)	KR100548854B1 (da)
CN (2)	CN1279040C (da)
AP (1)	AP1965A (da)
AR (2)	AR028622A1 (da)
AT (2)	ATE260914T1 (da)
AU (2)	AU5248201A (da)
BG (1)	BG65966B1 (da)
BR (1)	BRPI0110955B8 (da)
CA (1)	CA2408909C (da)
CR (1)	CR10145A (da)
CU (1)	CU23288B7 (da)
CY (2)	CY2008006I2 (da)
CZ (1)	CZ299102B6 (da)
DE (3)	DE122008000011I1 (da)
DK (2)	DK1284974T3 (da)
DZ (1)	DZ3464A1 (da)
EA (2)	EA005382B1 (da)
EE (1)	EE05110B1 (da)
EG (1)	EG24137A (da)
ES (3)	ES2215129T3 (da)
FR (1)	FR08C0007I2 (da)
GE (1)	GEP20063799B (da)
HK (3)	HK1054927A1 (da)
HR (1)	HRP20020938B1 (da)
HU (1)	HU225810B1 (da)
IL (2)	IL152531A0 (da)
IS (1)	IS2511B (da)
LT (1)	LTC1284974I2 (da)
LU (1)	LU91417I2 (da)
MA (1)	MA26902A1 (da)
ME (1)	ME00555B (da)
MX (1)	MXPA02011631A (da)
MY (3)	MY153023A (da)
NL (1)	NL300338I2 (da)
NO (3)	NO327892B1 (da)
NZ (1)	NZ521477A (da)
OA (1)	OA12264A (da)
PA (1)	PA8517101A1 (da)
PE (1)	PE20011371A1 (da)
PL (1)	PL200551B1 (da)
PT (2)	PT1284974E (da)
RS (2)	RS51436B (da)
SI (2)	SI1284974T1 (da)
SK (1)	SK286129B6 (da)
TN (1)	TNSN01077A1 (da)
TR (1)	TR200400541T4 (da)
TW (1)	TWI230160B (da)
UY (1)	UY26727A1 (da)
WO (1)	WO2001090106A2 (da)

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WO2008132128A2 (en) *	2007-04-27	2008-11-06	Solvay (Société Anonyme)	Synthesis of a pharmaceutically active compound
CA2716838C (en) *	2008-02-29	2014-01-07	Schering Corporation	Ccr5 antagonists as prophylactics for preventing hiv infection and methods of inhibiting transmission of same
CN101712679B (zh) *	2008-10-08	2013-04-10	中国科学院上海药物研究所	一种酰胺类化合物、其药物组合物及其制备方法和用途
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CN102140104B (zh) *	2010-02-03	2014-11-12	中国科学院上海药物研究所	1-(3-(s)-氨基丙基)-哌啶-4-氨基酰胺类化合物、其药物组合物及其制备方法和用途
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Also Published As

Publication number	Publication date
EP1526134A3 (en)	2006-11-29
IS6565A (is)	2002-09-24
HUP0302474A3 (en)	2007-05-29
IL152531A (en)	2010-05-17
BRPI0110955B1 (pt)	2016-06-28
MY153023A (en)	2014-12-31
AP1965A (en)	2009-03-04
AU2001252482C1 (en)	2001-12-03
EA007580B1 (ru)	2006-12-29
AP2002002663A0 (en)	2002-12-31
SI1284974T1 (en)	2004-08-31
HK1054927A1 (en)	2003-12-19
BR0110955A (pt)	2003-06-03
CA2408909C (en)	2006-06-27
ATE407134T1 (de)	2008-09-15
CZ299102B6 (cs)	2008-04-23
NO2020019I1 (no)	2020-06-30
CN1279040C (zh)	2006-10-11
CA2408909A1 (en)	2001-11-29
KR20030004417A (ko)	2003-01-14
UY26727A1 (es)	2001-12-28
PL359267A1 (en)	2004-08-23
SI1526134T1 (sl)	2008-12-31
HK1090836A1 (en)	2007-01-05
LTPA2008004I1 (lt)	2020-07-27
DK1284974T3 (da)	2004-06-07
PT1284974E (pt)	2004-06-30
NO20025227L (no)	2002-10-31
TR200400541T4 (tr)	2004-04-21
PL200551B1 (pl)	2009-01-30
EP1526134B1 (en)	2008-09-03
CY1108451T1 (el)	2014-04-09
ES2401812T3 (es)	2013-04-24
KR100548854B1 (ko)	2006-02-02
PA8517101A1 (es)	2002-10-24
CN1680371A (zh)	2005-10-12
DE60135685D1 (de)	2008-10-16
HU225810B1 (en)	2007-10-29
TWI230160B (en)	2005-04-01
YU82202A (sh)	2005-11-28
BRPI0110955B8 (pt)	2021-05-25
NL300338I2 (nl)	2008-06-02
TNSN01077A1 (fr)	2005-11-10
EP1990341A1 (en)	2008-11-12
GEP20063799B (en)	2006-04-25
ME00555A (en)	2011-12-20
DZ3464A1 (da)	2001-11-29
ES2311126T3 (es)	2009-02-01
MY156920A (en)	2016-04-15
NO327892B1 (no)	2009-10-12
KR100523501B1 (ko)	2005-10-25
NO20025227D0 (no)	2002-10-31
WO2001090106A2 (en)	2001-11-29
PE20011371A1 (es)	2002-01-18
NL300338I1 (nl)	2008-05-01
NO2010007I1 (no)	2010-04-08
IL152531A0 (en)	2003-05-29
RS20090438A (en)	2010-05-07
SK16432002A3 (sk)	2004-01-08
CU23288B7 (es)	2008-06-30
LU91417I2 (fr)	2008-04-22
EP1284974B1 (en)	2004-03-03
FR08C0007I2 (fr)	2009-01-15
ATE260914T1 (de)	2004-03-15
HK1078573A1 (en)	2006-03-17
OA12264A (en)	2003-11-10
LTC1284974I2 (lt)	2020-11-10
NZ521477A (en)	2004-07-30
EE05110B1 (et)	2008-12-15
ES2215129T3 (es)	2004-10-01
JP2003534343A (ja)	2003-11-18
BG65966B1 (bg)	2010-07-30
EP1990341B1 (en)	2013-01-23
HRP20020938A2 (en)	2005-02-28
LU91417I9 (da)	2019-01-02
RS50904B (sr)	2010-08-31
HRP20020938B1 (en)	2011-05-31
PT1526134E (pt)	2008-10-28
EE200200656A (et)	2004-06-15
JP3693957B2 (ja)	2005-09-14
ME00555B (me)	2011-12-20
AU2001252482B2 (en)	2006-01-19
AR060159A2 (es)	2008-05-28
CY2008006I1 (el)	2009-11-04
HUP0302474A2 (hu)	2003-11-28
DE60102233T2 (de)	2005-01-27
EP1284974A2 (en)	2003-02-26
EP1526134A2 (en)	2005-04-27
SK286129B6 (sk)	2008-04-07
CR10145A (es)	2008-08-19
RS51436B (en)	2011-04-30
CY2008006I2 (el)	2009-11-04
WO2001090106A3 (en)	2002-03-28
MY131019A (en)	2007-07-31
JP2005194283A (ja)	2005-07-21
EA005382B1 (ru)	2005-02-24
CZ20023806A3 (cs)	2004-01-14
DE122008000011I1 (de)	2008-06-05
EA200401056A1 (ru)	2005-04-28
KR20050046743A (ko)	2005-05-18
NO2010007I2 (no)	2013-09-09
CN100355753C (zh)	2007-12-19
AR028622A1 (es)	2003-05-14
DE60102233D1 (de)	2004-04-08
JP4854970B2 (ja)	2012-01-18
EA200201141A1 (ru)	2003-04-24
BG107140A (bg)	2003-05-30
MA26902A1 (fr)	2004-12-20
FR08C0007I1 (da)	2008-04-25
IS2511B (is)	2009-05-15
AU5248201A (en)	2001-12-03
MXPA02011631A (es)	2003-03-27
CN1437599A (zh)	2003-08-20
EG24137A (en)	2008-08-06

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