DK1522539T3 - Krystallinsk komposition indeholdende excitalopram - Google Patents

Krystallinsk komposition indeholdende excitalopram

Info

Publication number
DK1522539T3
DK1522539T3 DK04029282T DK04029282T DK1522539T3 DK 1522539 T3 DK1522539 T3 DK 1522539T3 DK 04029282 T DK04029282 T DK 04029282T DK 04029282 T DK04029282 T DK 04029282T DK 1522539 T3 DK1522539 T3 DK 1522539T3
Authority
DK
Denmark
Prior art keywords
excitalopram
composition containing
crystalline composition
crystalline
containing excitalopram
Prior art date
Application number
DK04029282T
Other languages
Danish (da)
English (en)
Inventor
Troels Volsgaard Christensen
Michiel Onne Elema
Shashank Mahashabde
Sebastian P Assenza
Ken Liljegren
Lene Andresen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8160647&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1522539(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of DK1522539T3 publication Critical patent/DK1522539T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
DK04029282T 2001-07-31 2002-07-25 Krystallinsk komposition indeholdende excitalopram DK1522539T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101164 2001-07-31
PCT/DK2002/000513 WO2003011278A1 (en) 2001-07-31 2002-07-25 Crystalline composition containing escitalopram

Publications (1)

Publication Number Publication Date
DK1522539T3 true DK1522539T3 (da) 2007-05-07

Family

ID=8160647

Family Applications (2)

Application Number Title Priority Date Filing Date
DK04029282T DK1522539T3 (da) 2001-07-31 2002-07-25 Krystallinsk komposition indeholdende excitalopram
DK02750846T DK1414435T3 (da) 2001-07-31 2002-07-25 Krystallinsk komposition indeholdende escitalopram

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK02750846T DK1414435T3 (da) 2001-07-31 2002-07-25 Krystallinsk komposition indeholdende escitalopram

Country Status (40)

Country Link
US (3) US6916941B2 (pt)
EP (2) EP1522539B1 (pt)
JP (4) JP2005525993A (pt)
KR (1) KR20040028947A (pt)
CN (2) CN1660074A (pt)
AR (1) AR034898A1 (pt)
AT (2) ATE352546T1 (pt)
AU (1) AU2002355624B2 (pt)
BG (1) BG108571A (pt)
BR (1) BR0206164A (pt)
CA (1) CA2451915C (pt)
CO (1) CO5560540A2 (pt)
CY (1) CY1106413T1 (pt)
DE (2) DE60202615T2 (pt)
DK (2) DK1522539T3 (pt)
EA (1) EA006213B1 (pt)
EG (1) EG24206A (pt)
ES (2) ES2233842T3 (pt)
HK (1) HK1070000A1 (pt)
HR (2) HRP20031073A2 (pt)
HU (1) HUP0401946A2 (pt)
IL (2) IL159326A0 (pt)
IS (1) IS7077A (pt)
MA (1) MA27349A1 (pt)
ME (1) MEP2108A (pt)
MX (1) MXPA04000849A (pt)
MY (1) MY126238A (pt)
NO (1) NO328346B1 (pt)
NZ (1) NZ530157A (pt)
PE (1) PE20030304A1 (pt)
PL (1) PL366995A1 (pt)
PT (2) PT1522539E (pt)
RS (1) RS8304A (pt)
SI (1) SI1414435T1 (pt)
TN (1) TNSN04021A1 (pt)
TR (1) TR200400189T2 (pt)
UA (1) UA79930C2 (pt)
UY (1) UY27404A1 (pt)
WO (1) WO2003011278A1 (pt)
ZA (1) ZA200309684B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1142926C (zh) 1999-04-14 2004-03-24 H·隆德贝克有限公司 制备西酞普兰的方法
US20030232881A1 (en) * 2000-10-27 2003-12-18 H. Lundbeck A/S Crystals of pharmaceutically acceptable salts of citalopram, methods of crystallization, and pharmaceutical compositions comprising them
US20030109577A1 (en) * 2000-10-27 2003-06-12 Ken Liljegren Pharmaceutical composition containing citalopram
IL159326A0 (en) 2001-07-31 2004-06-01 Lundbeck & Co As H Crystalline composition containing escitalopram
PE20040991A1 (es) 2002-08-12 2004-12-27 Lundbeck & Co As H Separacion de intermediarios para la preparacion de escitalopram
TR200504022T1 (tr) * 2003-03-24 2006-08-21 Hetero Drugs Limited (S)-sitalopram oksalatın yeni sıvı kristal formları.
US20040265375A1 (en) * 2003-04-16 2004-12-30 Platteeuw Johannes J. Orally disintegrating tablets
TWI339651B (en) * 2004-02-12 2011-04-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
US20050196453A1 (en) * 2004-03-05 2005-09-08 H. Lundbeck A/S Crystalline composition containing escitalopram
WO2005084643A1 (en) * 2004-03-05 2005-09-15 H. Lundbeck A/S Crystalline composition containing escitalopram oxalate
WO2006123243A2 (en) * 2005-05-20 2006-11-23 Aurobindo Pharma Limited Pharmaceutical dosage forms comprising escitalopram in form of granules
TWI358407B (en) * 2005-06-22 2012-02-21 Lundbeck & Co As H Crystalline base of escitalopram and orodispersibl
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
US20070098804A1 (en) * 2005-08-29 2007-05-03 Judith Aronhime Solid particulate tadalafil having a bimodal particle size distribution
EA200801081A1 (ru) 2005-10-14 2008-10-30 Х. Лундбекк А/С Способы лечения расстройств центральной нервной системы комбинацией малых доз эсциталопрама и бупропиона
US20070134322A1 (en) * 2005-12-14 2007-06-14 Forest Laboratories, Inc. Modified and pulsatile release pharmaceutical formulations of escitalopram
GB0601286D0 (en) 2006-01-23 2006-03-01 Sandoz Ag Asymmetric synthesis
WO2008059514A2 (en) * 2006-07-31 2008-05-22 Cadila Healthcare Limited Process for preparing escitalopram
EP2086509A1 (en) * 2006-10-20 2009-08-12 Ratiopharm GmbH Escitalopram and solid pharmaceutical composition comprising the same
US20090048336A1 (en) * 2007-08-17 2009-02-19 Naveen Kumar Kolla Escitalopram oxalate powders
EP2291177A2 (en) * 2008-05-05 2011-03-09 Farmaprojects, S.A. Stable pharmaceutical compositions and their processes for preparation suitable for industrial scale
EP2116231A1 (en) 2008-05-07 2009-11-11 Hexal Ag Granulate comprising escitalopram oxalate
GR20080100696A (el) 2008-10-23 2010-05-13 Genepharm �.�. Φαρμακοτεχνικη μορφη με βελτιωμενη γευση του φαρμακευτικα αποδεκτου αλατος εσιταλοπραμης
ITMI20120448A1 (it) * 2012-01-30 2013-07-31 Carthesia Sas Composizione liofilizzata di escitalopram ossalato per somministrazione sublinguale
ITMI20120106A1 (it) * 2012-01-30 2013-07-31 Carthesia S A S Pastiglie liofilizzate di escitalopram ossalato per somministrazione sublinguale
CN106397249A (zh) * 2015-08-03 2017-02-15 深圳信立泰药业股份有限公司 一种高稳定性lcz696结晶粉末及其制备方法
JP2018016569A (ja) * 2016-07-26 2018-02-01 株式会社トクヤマ （１ｓ）−１−［３−（ジメチルアミノ）プロピル］−１−（４−フルオロフェニル）−１，３−ジヒドロイソベンゾフラン−５−カルボニトリル蓚酸塩の製造方法
JP6423133B1 (ja) * 2017-04-10 2018-11-14 東和薬品株式会社 エスシタロプラム医薬組成物
CN107441052A (zh) * 2017-06-21 2017-12-08 山东京卫制药有限公司 一种含有草酸艾司西酞普兰的片剂及其制备方法
KR102089737B1 (ko) * 2017-11-01 2020-03-16 한국화학연구원 에씨탈로프람을 함유한 미립구형 서방출 주사제 및 그의 제조방법
JP7453859B2 (ja) 2020-06-22 2024-03-21 東和薬品株式会社 エスシタロプラム錠剤

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (pt) 1965-03-18
GB1358915A (en) 1971-09-13 1974-07-03 Merck & Co Inc Directly compressed tablet and composition therefor
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
DE3688827T2 (de) 1985-10-25 1994-03-31 Beecham Group Plc Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel.
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
GB9325644D0 (en) 1993-12-15 1994-02-16 Smithkline Beecham Plc Novel formulation
US5683720A (en) 1994-10-28 1997-11-04 Fuisz Technologies Ltd. Liquiflash particles and method of making same
EP0714663A3 (en) 1994-11-28 1997-01-15 Lilly Co Eli Potentiation of drug responses by serotonin 1A receptor antagonists
AU5966196A (en) 1995-06-08 1997-01-09 Eli Lilly And Company Methods of treating cold and allergic rhinitis
DE1015416T1 (de) 1997-07-08 2000-10-05 Lundbeck A S Kobenhavn Valby H Verfahren zur herstellung von citalopram
GB9714841D0 (en) 1997-07-14 1997-09-17 Smithkline Beecham Plc Treatment method
US5980941A (en) 1997-08-20 1999-11-09 Fuisz Technologies Ltd. Self-binding shearform compositions
US5840334A (en) 1997-08-20 1998-11-24 Fuisz Technologies Ltd. Self-binding shearform compositions
US5869098A (en) 1997-08-20 1999-02-09 Fuisz Technologies Ltd. Fast-dissolving comestible units formed under high-speed/high-pressure conditions
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
JP3813820B2 (ja) * 1997-11-11 2006-08-23 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
WO2000023431A1 (en) 1998-10-20 2000-04-27 H. Lundbeck A/S Method for the preparation of citalopram
TWI230618B (en) * 1998-12-15 2005-04-11 Gilead Sciences Inc Pharmaceutical compositions of 9-[2-[[bis[(pivaloyloxy)methyl]phosphono]methoxy]ethyl]adenine and tablets or capsules containing the same
CN1142926C (zh) 1999-04-14 2004-03-24 H·隆德贝克有限公司 制备西酞普兰的方法
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
AR021155A1 (es) 1999-07-08 2002-06-12 Lundbeck & Co As H Tratamiento de desordenes neuroticos
CA2385749A1 (en) * 1999-09-28 2001-04-05 H. Lundbeck A/S Melt granulated composition and modified release dosage form prepared from said composition
GB2357762B (en) 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
US6977306B2 (en) 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof
US20030232881A1 (en) * 2000-10-27 2003-12-18 H. Lundbeck A/S Crystals of pharmaceutically acceptable salts of citalopram, methods of crystallization, and pharmaceutical compositions comprising them
IL159326A0 (en) 2001-07-31 2004-06-01 Lundbeck & Co As H Crystalline composition containing escitalopram

Also Published As

Publication number Publication date
MXPA04000849A (es) 2004-05-14
MA27349A1 (fr) 2005-06-01
HRP20080410A2 (en) 2008-10-31
PT1414435E (pt) 2005-05-31
UY27404A1 (es) 2003-02-28
IS7077A (is) 2003-12-15
EG24206A (en) 2008-10-21
WO2003011278A1 (en) 2003-02-13
HUP0401946A2 (hu) 2005-01-28
AR034898A1 (es) 2004-03-24
EP1414435A1 (en) 2004-05-06
HRP20031073A2 (en) 2004-04-30
JP2012211186A (ja) 2012-11-01
US20030212128A1 (en) 2003-11-13
AU2002355624B2 (en) 2006-02-02
BG108571A (en) 2005-02-28
CA2451915C (en) 2010-09-21
EP1522539A1 (en) 2005-04-13
EP1522539B1 (en) 2007-01-24
JP2011195591A (ja) 2011-10-06
DE60202615T2 (de) 2006-01-12
PT1522539E (pt) 2007-03-30
ES2280892T3 (es) 2007-09-16
DE60202615D1 (de) 2005-02-17
DK1414435T3 (da) 2005-05-09
HRPK20080410B3 (en) 2009-09-30
ATE352546T1 (de) 2007-02-15
CO5560540A2 (es) 2005-09-30
NZ530157A (en) 2007-06-29
NO20040380L (no) 2004-01-28
HK1070000A1 (en) 2005-06-10
SI1414435T1 (en) 2005-06-30
CN1536997A (zh) 2004-10-13
JP2005525993A (ja) 2005-09-02
BR0206164A (pt) 2003-10-28
CN1311819C (zh) 2007-04-25
TNSN04021A1 (en) 2006-06-01
US6916941B2 (en) 2005-07-12
DE60217932T2 (de) 2007-08-30
US20080305164A1 (en) 2008-12-11
TR200400189T2 (tr) 2004-12-21
ES2233842T3 (es) 2005-06-16
NO328346B1 (no) 2010-02-01
UA79930C2 (en) 2007-08-10
EA200400243A1 (ru) 2004-06-24
PE20030304A1 (es) 2003-03-27
IL159326A0 (en) 2004-06-01
CY1106413T1 (el) 2011-10-12
IL159326A (en) 2010-05-31
US7420069B2 (en) 2008-09-02
CA2451915A1 (en) 2003-02-13
KR20040028947A (ko) 2004-04-03
ZA200309684B (en) 2004-12-22
US20050147674A1 (en) 2005-07-07
EP1414435B1 (en) 2005-01-12
JP2010150283A (ja) 2010-07-08
DE60217932D1 (de) 2007-03-15
CN1660074A (zh) 2005-08-31
ATE286730T1 (de) 2005-01-15
PL366995A1 (en) 2005-02-07
MY126238A (en) 2006-09-29
MEP2108A (xx) 2010-02-10
JP4971477B2 (ja) 2012-07-11
JP5719811B2 (ja) 2015-05-20
EA006213B1 (ru) 2005-10-27
RS8304A (en) 2006-12-15
JP5192568B2 (ja) 2013-05-08

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