HRP20031073A2 - Crystalline composition containing escitalopram - Google Patents

Crystalline composition containing escitalopram

Info

Publication number
HRP20031073A2
HRP20031073A2 HR20031073A HRP20031073A HRP20031073A2 HR P20031073 A2 HRP20031073 A2 HR P20031073A2 HR 20031073 A HR20031073 A HR 20031073A HR P20031073 A HRP20031073 A HR P20031073A HR P20031073 A2 HRP20031073 A2 HR P20031073A2
Authority
HR
Croatia
Prior art keywords
composition containing
crystalline composition
containing escitalopram
escitalopram
crystalline
Prior art date
Application number
HR20031073A
Other languages
English (en)
Inventor
Troels Volsgaard Christensen
Ken Liljegren
Michiel Onne Elema
Lene Andresen
Shashank Mahashabde
Sebastian P Assenza
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8160647&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20031073(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of HRP20031073A2 publication Critical patent/HRP20031073A2/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
HR20031073A 2001-07-31 2003-12-23 Crystalline composition containing escitalopram HRP20031073A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101164 2001-07-31
PCT/DK2002/000513 WO2003011278A1 (en) 2001-07-31 2002-07-25 Crystalline composition containing escitalopram

Publications (1)

Publication Number Publication Date
HRP20031073A2 true HRP20031073A2 (en) 2004-04-30

Family

ID=8160647

Family Applications (2)

Application Number Title Priority Date Filing Date
HR20031073A HRP20031073A2 (en) 2001-07-31 2003-12-23 Crystalline composition containing escitalopram
HR20080410A HRPK20080410B3 (en) 2001-07-31 2008-08-22 Crystalline composition containing escitalopram

Family Applications After (1)

Application Number Title Priority Date Filing Date
HR20080410A HRPK20080410B3 (en) 2001-07-31 2008-08-22 Crystalline composition containing escitalopram

Country Status (40)

Country Link
US (3) US6916941B2 (xx)
EP (2) EP1522539B1 (xx)
JP (4) JP2005525993A (xx)
KR (1) KR20040028947A (xx)
CN (2) CN1311819C (xx)
AR (1) AR034898A1 (xx)
AT (2) ATE352546T1 (xx)
AU (1) AU2002355624B2 (xx)
BG (1) BG108571A (xx)
BR (1) BR0206164A (xx)
CA (1) CA2451915C (xx)
CO (1) CO5560540A2 (xx)
CY (1) CY1106413T1 (xx)
DE (2) DE60217932T2 (xx)
DK (2) DK1414435T3 (xx)
EA (1) EA006213B1 (xx)
EG (1) EG24206A (xx)
ES (2) ES2280892T3 (xx)
HK (1) HK1070000A1 (xx)
HR (2) HRP20031073A2 (xx)
HU (1) HUP0401946A2 (xx)
IL (2) IL159326A0 (xx)
IS (1) IS7077A (xx)
MA (1) MA27349A1 (xx)
ME (1) MEP2108A (xx)
MX (1) MXPA04000849A (xx)
MY (1) MY126238A (xx)
NO (1) NO328346B1 (xx)
NZ (1) NZ530157A (xx)
PE (1) PE20030304A1 (xx)
PL (1) PL366995A1 (xx)
PT (2) PT1414435E (xx)
RS (1) RS8304A (xx)
SI (1) SI1414435T1 (xx)
TN (1) TNSN04021A1 (xx)
TR (1) TR200400189T2 (xx)
UA (1) UA79930C2 (xx)
UY (1) UY27404A1 (xx)
WO (1) WO2003011278A1 (xx)
ZA (1) ZA200309684B (xx)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200102957T2 (tr) 1999-04-14 2004-12-21 H. Lundbeck A/S Sitalopram hazırlanması için metod.
US20030232881A1 (en) * 2000-10-27 2003-12-18 H. Lundbeck A/S Crystals of pharmaceutically acceptable salts of citalopram, methods of crystallization, and pharmaceutical compositions comprising them
US20030109577A1 (en) * 2000-10-27 2003-06-12 Ken Liljegren Pharmaceutical composition containing citalopram
ES2280892T3 (es) 2001-07-31 2007-09-16 H. Lundbeck A/S Composicion cristalina que contiene escitalopram.
TWI306846B (en) 2002-08-12 2009-03-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
US20050154052A1 (en) * 2003-03-24 2005-07-14 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
US20040265375A1 (en) * 2003-04-16 2004-12-30 Platteeuw Johannes J. Orally disintegrating tablets
TWI339651B (en) * 2004-02-12 2011-04-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
US20050196453A1 (en) * 2004-03-05 2005-09-08 H. Lundbeck A/S Crystalline composition containing escitalopram
EA200601641A1 (ru) * 2004-03-05 2006-12-29 Х. Лундбекк А/С Кристаллическая композиция, содержащая оксалат эсциталопрама
WO2006123243A2 (en) * 2005-05-20 2006-11-23 Aurobindo Pharma Limited Pharmaceutical dosage forms comprising escitalopram in form of granules
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
TWI347942B (en) * 2005-06-22 2011-09-01 Lundbeck & Co As H Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
BRPI0606122A2 (pt) * 2005-08-29 2009-06-02 Teva Pharma tadalafil particulado sólido que tem uma distribuição de tamanho de partìcula bimodal
EP1954257A4 (en) 2005-10-14 2009-05-20 Lundbeck & Co As H METHOD FOR TREATING DISORDERS OF THE CENTRAL NERVOUS SYSTEM WITH A LOW-DOSED COMBINATION OF ESCITALOPRAM AND BUPROPION
US20070134322A1 (en) * 2005-12-14 2007-06-14 Forest Laboratories, Inc. Modified and pulsatile release pharmaceutical formulations of escitalopram
GB0601286D0 (en) 2006-01-23 2006-03-01 Sandoz Ag Asymmetric synthesis
WO2008059514A2 (en) * 2006-07-31 2008-05-22 Cadila Healthcare Limited Process for preparing escitalopram
EP2086509A1 (en) * 2006-10-20 2009-08-12 Ratiopharm GmbH Escitalopram and solid pharmaceutical composition comprising the same
US20090048336A1 (en) * 2007-08-17 2009-02-19 Naveen Kumar Kolla Escitalopram oxalate powders
WO2009135646A2 (en) * 2008-05-05 2009-11-12 Farmaprojects, Sa Stable pharmaceutical compositions and their processes for preparation suitable for industrial scale
EP2116231A1 (en) 2008-05-07 2009-11-11 Hexal Ag Granulate comprising escitalopram oxalate
GR20080100696A (el) 2008-10-23 2010-05-13 Genepharm �.�. Φαρμακοτεχνικη μορφη με βελτιωμενη γευση του φαρμακευτικα αποδεκτου αλατος εσιταλοπραμης
ITMI20120106A1 (it) * 2012-01-30 2013-07-31 Carthesia S A S Pastiglie liofilizzate di escitalopram ossalato per somministrazione sublinguale
ITMI20120448A1 (it) * 2012-01-30 2013-07-31 Carthesia Sas Composizione liofilizzata di escitalopram ossalato per somministrazione sublinguale
CN106389374A (zh) * 2015-08-03 2017-02-15 深圳信立泰药业股份有限公司 一种含有lcz696的药物组合物及其制备方法
JP2018016569A (ja) * 2016-07-26 2018-02-01 株式会社トクヤマ (1s)−1−[3−(ジメチルアミノ)プロピル]−1−(4−フルオロフェニル)−1,3−ジヒドロイソベンゾフラン−5−カルボニトリル蓚酸塩の製造方法
JP6423133B1 (ja) * 2017-04-10 2018-11-14 東和薬品株式会社 エスシタロプラム医薬組成物
CN107441052A (zh) * 2017-06-21 2017-12-08 山东京卫制药有限公司 一种含有草酸艾司西酞普兰的片剂及其制备方法
KR102089737B1 (ko) 2017-11-01 2020-03-16 한국화학연구원 에씨탈로프람을 함유한 미립구형 서방출 주사제 및 그의 제조방법
JP7453859B2 (ja) 2020-06-22 2024-03-21 東和薬品株式会社 エスシタロプラム錠剤

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Publication number Priority date Publication date Assignee Title
GB1143702A (xx) * 1965-03-18
GB1358915A (en) 1971-09-13 1974-07-03 Merck & Co Inc Directly compressed tablet and composition therefor
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
EP0223403B1 (en) * 1985-10-25 1993-08-04 Beecham Group Plc Piperidine derivative, its preparation, and its use as medicament
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) * 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
GB9325644D0 (en) 1993-12-15 1994-02-16 Smithkline Beecham Plc Novel formulation
US5683720A (en) * 1994-10-28 1997-11-04 Fuisz Technologies Ltd. Liquiflash particles and method of making same
EP0714663A3 (en) 1994-11-28 1997-01-15 Lilly Co Eli Potentiation of drug responses by serotonin 1A receptor antagonists
WO1996041633A1 (en) 1995-06-08 1996-12-27 Eli Lilly And Company Methods of treating cold and allergic rhinitis
PT1015416E (pt) 1997-07-08 2002-03-28 Lundbeck & Co As H Metodo para a producao de citalopram
GB9714841D0 (en) 1997-07-14 1997-09-17 Smithkline Beecham Plc Treatment method
US5840334A (en) * 1997-08-20 1998-11-24 Fuisz Technologies Ltd. Self-binding shearform compositions
US5869098A (en) * 1997-08-20 1999-02-09 Fuisz Technologies Ltd. Fast-dissolving comestible units formed under high-speed/high-pressure conditions
US5980941A (en) * 1997-08-20 1999-11-09 Fuisz Technologies Ltd. Self-binding shearform compositions
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
AU738359B2 (en) * 1997-11-11 2001-09-13 H. Lundbeck A/S Method for the preparation of citalopram
HU228576B1 (en) 1998-10-20 2013-04-29 Lundbeck & Co As H Method for the preparation of citalopram
TWI230618B (en) * 1998-12-15 2005-04-11 Gilead Sciences Inc Pharmaceutical compositions of 9-[2-[[bis[(pivaloyloxy)methyl]phosphono]methoxy]ethyl]adenine and tablets or capsules containing the same
TR200102957T2 (tr) 1999-04-14 2004-12-21 H. Lundbeck A/S Sitalopram hazırlanması için metod.
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
AR021155A1 (es) 1999-07-08 2002-06-12 Lundbeck & Co As H Tratamiento de desordenes neuroticos
EP1220658A1 (en) * 1999-09-28 2002-07-10 H. Lundbeck A/S Melt granulated composition and modified release dosage form prepared from said composition
GB2357762B (en) 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
US6977306B2 (en) * 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof
US20030232881A1 (en) * 2000-10-27 2003-12-18 H. Lundbeck A/S Crystals of pharmaceutically acceptable salts of citalopram, methods of crystallization, and pharmaceutical compositions comprising them
ES2280892T3 (es) 2001-07-31 2007-09-16 H. Lundbeck A/S Composicion cristalina que contiene escitalopram.

Also Published As

Publication number Publication date
JP2011195591A (ja) 2011-10-06
HK1070000A1 (en) 2005-06-10
PT1522539E (pt) 2007-03-30
JP2010150283A (ja) 2010-07-08
BG108571A (en) 2005-02-28
UA79930C2 (en) 2007-08-10
NZ530157A (en) 2007-06-29
IL159326A (en) 2010-05-31
CA2451915A1 (en) 2003-02-13
CO5560540A2 (es) 2005-09-30
US20030212128A1 (en) 2003-11-13
EP1522539A1 (en) 2005-04-13
AR034898A1 (es) 2004-03-24
UY27404A1 (es) 2003-02-28
WO2003011278A1 (en) 2003-02-13
IS7077A (is) 2003-12-15
DE60217932T2 (de) 2007-08-30
DE60202615T2 (de) 2006-01-12
JP2012211186A (ja) 2012-11-01
US20050147674A1 (en) 2005-07-07
MXPA04000849A (es) 2004-05-14
TNSN04021A1 (en) 2006-06-01
US6916941B2 (en) 2005-07-12
ATE286730T1 (de) 2005-01-15
ZA200309684B (en) 2004-12-22
US20080305164A1 (en) 2008-12-11
JP5192568B2 (ja) 2013-05-08
EP1414435A1 (en) 2004-05-06
MA27349A1 (fr) 2005-06-01
DE60217932D1 (de) 2007-03-15
EP1414435B1 (en) 2005-01-12
HRPK20080410B3 (en) 2009-09-30
DE60202615D1 (de) 2005-02-17
JP5719811B2 (ja) 2015-05-20
EP1522539B1 (en) 2007-01-24
KR20040028947A (ko) 2004-04-03
PL366995A1 (en) 2005-02-07
EG24206A (en) 2008-10-21
ES2233842T3 (es) 2005-06-16
AU2002355624B2 (en) 2006-02-02
MEP2108A (xx) 2010-02-10
CA2451915C (en) 2010-09-21
PT1414435E (pt) 2005-05-31
CN1536997A (zh) 2004-10-13
MY126238A (en) 2006-09-29
CY1106413T1 (el) 2011-10-12
DK1414435T3 (da) 2005-05-09
JP2005525993A (ja) 2005-09-02
BR0206164A (pt) 2003-10-28
TR200400189T2 (tr) 2004-12-21
US7420069B2 (en) 2008-09-02
DK1522539T3 (da) 2007-05-07
EA200400243A1 (ru) 2004-06-24
IL159326A0 (en) 2004-06-01
HUP0401946A2 (hu) 2005-01-28
EA006213B1 (ru) 2005-10-27
NO328346B1 (no) 2010-02-01
PE20030304A1 (es) 2003-03-27
HRP20080410A2 (en) 2008-10-31
JP4971477B2 (ja) 2012-07-11
NO20040380L (no) 2004-01-28
CN1311819C (zh) 2007-04-25
ATE352546T1 (de) 2007-02-15
RS8304A (xx) 2006-12-15
ES2280892T3 (es) 2007-09-16
SI1414435T1 (en) 2005-06-30
CN1660074A (zh) 2005-08-31

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