BR0206164A - Partìculas cristalinas de oxalato de escitalopram, método para a produção de partìculas cristalinas de oxalato de escitalopram, e, forma de dosagem unitária sólida - Google Patents

Partìculas cristalinas de oxalato de escitalopram, método para a produção de partìculas cristalinas de oxalato de escitalopram, e, forma de dosagem unitária sólida

Info

Publication number
BR0206164A
BR0206164A BR0206164-3A BR0206164A BR0206164A BR 0206164 A BR0206164 A BR 0206164A BR 0206164 A BR0206164 A BR 0206164A BR 0206164 A BR0206164 A BR 0206164A
Authority
BR
Brazil
Prior art keywords
crystalline particles
escitalopram oxalate
oxalate crystalline
production
dosage form
Prior art date
Application number
BR0206164-3A
Other languages
English (en)
Inventor
Troels Volsgaard Christensen
Ken Liljegren
Michiel Onne Elema
Lene Andresen
Shashank Mahashabde
Sebastian O Assenza
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8160647&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0206164(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of BR0206164A publication Critical patent/BR0206164A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Abstract

"PARTìCULAS CRISTALINAS DE OXALATO DE ESCITALOPRAM, MéTODO PARA A PRODUçãO DE PARTìCULAS CRISTALINAS DE OXALATO DE ESCITALOPRAM, E, FORMA DE DOSAGEM UNITáRIA SóLIDA". Resumo: são apresentadas partículas cristalinas de oxalato de escitalopram com um tamanho de partícula de pelo menos 40 <109>g. São apresentados, o método para produzir as referidas partículas cristalinas e as composições farmacêuticas compreendendo as referidas partículas cristalinas.
BR0206164-3A 2001-07-31 2002-07-25 Partìculas cristalinas de oxalato de escitalopram, método para a produção de partìculas cristalinas de oxalato de escitalopram, e, forma de dosagem unitária sólida BR0206164A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101164 2001-07-31
PCT/DK2002/000513 WO2003011278A1 (en) 2001-07-31 2002-07-25 Crystalline composition containing escitalopram

Publications (1)

Publication Number Publication Date
BR0206164A true BR0206164A (pt) 2003-10-28

Family

ID=8160647

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0206164-3A BR0206164A (pt) 2001-07-31 2002-07-25 Partìculas cristalinas de oxalato de escitalopram, método para a produção de partìculas cristalinas de oxalato de escitalopram, e, forma de dosagem unitária sólida

Country Status (40)

Country Link
US (3) US6916941B2 (pt)
EP (2) EP1414435B1 (pt)
JP (4) JP2005525993A (pt)
KR (1) KR20040028947A (pt)
CN (2) CN1660074A (pt)
AR (1) AR034898A1 (pt)
AT (2) ATE286730T1 (pt)
AU (1) AU2002355624B2 (pt)
BG (1) BG108571A (pt)
BR (1) BR0206164A (pt)
CA (1) CA2451915C (pt)
CO (1) CO5560540A2 (pt)
CY (1) CY1106413T1 (pt)
DE (2) DE60217932T2 (pt)
DK (2) DK1522539T3 (pt)
EA (1) EA006213B1 (pt)
EG (1) EG24206A (pt)
ES (2) ES2233842T3 (pt)
HK (1) HK1070000A1 (pt)
HR (2) HRP20031073A2 (pt)
HU (1) HUP0401946A2 (pt)
IL (2) IL159326A0 (pt)
IS (1) IS7077A (pt)
MA (1) MA27349A1 (pt)
ME (1) MEP2108A (pt)
MX (1) MXPA04000849A (pt)
MY (1) MY126238A (pt)
NO (1) NO328346B1 (pt)
NZ (1) NZ530157A (pt)
PE (1) PE20030304A1 (pt)
PL (1) PL366995A1 (pt)
PT (2) PT1414435E (pt)
RS (1) RS8304A (pt)
SI (1) SI1414435T1 (pt)
TN (1) TNSN04021A1 (pt)
TR (1) TR200400189T2 (pt)
UA (1) UA79930C2 (pt)
UY (1) UY27404A1 (pt)
WO (1) WO2003011278A1 (pt)
ZA (1) ZA200309684B (pt)

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Publication number Priority date Publication date Assignee Title
ES2195554T5 (es) 1999-04-14 2010-02-02 H. Lundbeck A/S Metodo para la preparacion de citalopram.
US20030109577A1 (en) * 2000-10-27 2003-06-12 Ken Liljegren Pharmaceutical composition containing citalopram
US20030232881A1 (en) * 2000-10-27 2003-12-18 H. Lundbeck A/S Crystals of pharmaceutically acceptable salts of citalopram, methods of crystallization, and pharmaceutical compositions comprising them
TR200400189T2 (tr) * 2001-07-31 2004-12-21 H.Lundbeck A/S Esitalopram içeren kristal yapılı bileşim.
PE20040991A1 (es) 2002-08-12 2004-12-27 Lundbeck & Co As H Separacion de intermediarios para la preparacion de escitalopram
AU2003223105A1 (en) * 2003-03-24 2004-10-18 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
US20040265375A1 (en) * 2003-04-16 2004-12-30 Platteeuw Johannes J. Orally disintegrating tablets
TWI339651B (en) * 2004-02-12 2011-04-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
US20050196453A1 (en) 2004-03-05 2005-09-08 H. Lundbeck A/S Crystalline composition containing escitalopram
WO2005084643A1 (en) * 2004-03-05 2005-09-15 H. Lundbeck A/S Crystalline composition containing escitalopram oxalate
EP1901714A2 (en) * 2005-05-20 2008-03-26 Aurobindo Pharma Limited Pharmaceutical dosage forms comprising escitalopram in form of granules
TWI347942B (en) * 2005-06-22 2011-09-01 Lundbeck & Co As H Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
ES2308750T3 (es) * 2005-08-29 2008-12-01 Teva Pharmaceutical Industries Ltd Tadalafil en particulas solidas que presenta una distribucion de particulas bimodal.
JP2009511606A (ja) 2005-10-14 2009-03-19 ハー・ルンドベック・アクチエゼルスカベット エスシタロプラムおよびブプロピオンの低用量の併用を用いる中枢神経系障害の治療方法
US20070134322A1 (en) * 2005-12-14 2007-06-14 Forest Laboratories, Inc. Modified and pulsatile release pharmaceutical formulations of escitalopram
GB0601286D0 (en) 2006-01-23 2006-03-01 Sandoz Ag Asymmetric synthesis
WO2008059514A2 (en) * 2006-07-31 2008-05-22 Cadila Healthcare Limited Process for preparing escitalopram
CA2672925A1 (en) 2006-10-20 2008-04-24 Ratiopharm Gmbh Escitalopram and solid pharmaceutical composition comprising the same
US20090048336A1 (en) * 2007-08-17 2009-02-19 Naveen Kumar Kolla Escitalopram oxalate powders
WO2009135646A2 (en) * 2008-05-05 2009-11-12 Farmaprojects, Sa Stable pharmaceutical compositions and their processes for preparation suitable for industrial scale
EP2116231A1 (en) 2008-05-07 2009-11-11 Hexal Ag Granulate comprising escitalopram oxalate
GR20080100696A (el) 2008-10-23 2010-05-13 Genepharm �.�. Φαρμακοτεχνικη μορφη με βελτιωμενη γευση του φαρμακευτικα αποδεκτου αλατος εσιταλοπραμης
ITMI20120448A1 (it) * 2012-01-30 2013-07-31 Carthesia Sas Composizione liofilizzata di escitalopram ossalato per somministrazione sublinguale
ITMI20120106A1 (it) * 2012-01-30 2013-07-31 Carthesia S A S Pastiglie liofilizzate di escitalopram ossalato per somministrazione sublinguale
CN106397249A (zh) * 2015-08-03 2017-02-15 深圳信立泰药业股份有限公司 一种高稳定性lcz696结晶粉末及其制备方法
JP2018016569A (ja) * 2016-07-26 2018-02-01 株式会社トクヤマ （１ｓ）−１−［３−（ジメチルアミノ）プロピル］−１−（４−フルオロフェニル）−１，３−ジヒドロイソベンゾフラン−５−カルボニトリル蓚酸塩の製造方法
WO2018190294A1 (ja) * 2017-04-10 2018-10-18 東和薬品株式会社 エスシタロプラム医薬組成物
CN107441052A (zh) * 2017-06-21 2017-12-08 山东京卫制药有限公司 一种含有草酸艾司西酞普兰的片剂及其制备方法
KR102089737B1 (ko) * 2017-11-01 2020-03-16 한국화학연구원 에씨탈로프람을 함유한 미립구형 서방출 주사제 및 그의 제조방법
JP7453859B2 (ja) 2020-06-22 2024-03-21 東和薬品株式会社 エスシタロプラム錠剤

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ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
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TR200400189T2 (tr) 2001-07-31 2004-12-21 H.Lundbeck A/S Esitalopram içeren kristal yapılı bileşim.

Also Published As

Publication number Publication date
HUP0401946A2 (hu) 2005-01-28
EP1522539A1 (en) 2005-04-13
AU2002355624B2 (en) 2006-02-02
HRP20031073A2 (en) 2004-04-30
MY126238A (en) 2006-09-29
CN1311819C (zh) 2007-04-25
NZ530157A (en) 2007-06-29
MA27349A1 (fr) 2005-06-01
PT1414435E (pt) 2005-05-31
US6916941B2 (en) 2005-07-12
MXPA04000849A (es) 2004-05-14
JP2005525993A (ja) 2005-09-02
NO328346B1 (no) 2010-02-01
ATE286730T1 (de) 2005-01-15
SI1414435T1 (en) 2005-06-30
US20030212128A1 (en) 2003-11-13
AR034898A1 (es) 2004-03-24
JP2012211186A (ja) 2012-11-01
DE60217932D1 (de) 2007-03-15
TNSN04021A1 (en) 2006-06-01
EP1414435B1 (en) 2005-01-12
CN1536997A (zh) 2004-10-13
DK1522539T3 (da) 2007-05-07
WO2003011278A1 (en) 2003-02-13
DK1414435T3 (da) 2005-05-09
UY27404A1 (es) 2003-02-28
PE20030304A1 (es) 2003-03-27
DE60202615T2 (de) 2006-01-12
IL159326A0 (en) 2004-06-01
HK1070000A1 (en) 2005-06-10
RS8304A (en) 2006-12-15
US20080305164A1 (en) 2008-12-11
HRPK20080410B3 (en) 2009-09-30
JP5192568B2 (ja) 2013-05-08
ES2280892T3 (es) 2007-09-16
ZA200309684B (en) 2004-12-22
IS7077A (is) 2003-12-15
ATE352546T1 (de) 2007-02-15
JP2010150283A (ja) 2010-07-08
JP2011195591A (ja) 2011-10-06
CN1660074A (zh) 2005-08-31
EP1414435A1 (en) 2004-05-06
DE60202615D1 (de) 2005-02-17
JP4971477B2 (ja) 2012-07-11
IL159326A (en) 2010-05-31
CA2451915A1 (en) 2003-02-13
KR20040028947A (ko) 2004-04-03
US20050147674A1 (en) 2005-07-07
EA006213B1 (ru) 2005-10-27
PL366995A1 (en) 2005-02-07
TR200400189T2 (tr) 2004-12-21
JP5719811B2 (ja) 2015-05-20
MEP2108A (xx) 2010-02-10
EA200400243A1 (ru) 2004-06-24
EG24206A (en) 2008-10-21
UA79930C2 (en) 2007-08-10
HRP20080410A2 (en) 2008-10-31
CA2451915C (en) 2010-09-21
DE60217932T2 (de) 2007-08-30
EP1522539B1 (en) 2007-01-24
CO5560540A2 (es) 2005-09-30
PT1522539E (pt) 2007-03-30
US7420069B2 (en) 2008-09-02
ES2233842T3 (es) 2005-06-16
CY1106413T1 (el) 2011-10-12
NO20040380L (no) 2004-01-28
BG108571A (en) 2005-02-28

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIMENTO DO PRESENTE PEDIDO UMA VEZ QUE INCIDE NO ARTIGO 8O E 13 DA LPI ( LEI 9279/96 )

B12B Appeal against refusal [chapter 12.2 patent gazette]