DK1377586T3 - Tricykliske diazepiner som tocolytiske oxytocinreceptorantagonister - Google Patents

Tricykliske diazepiner som tocolytiske oxytocinreceptorantagonister

Info

Publication number
DK1377586T3
DK1377586T3 DK02731343T DK02731343T DK1377586T3 DK 1377586 T3 DK1377586 T3 DK 1377586T3 DK 02731343 T DK02731343 T DK 02731343T DK 02731343 T DK02731343 T DK 02731343T DK 1377586 T3 DK1377586 T3 DK 1377586T3
Authority
DK
Denmark
Prior art keywords
compounds
treatment
prevention
useful
receptor antagonists
Prior art date
Application number
DK02731343T
Other languages
English (en)
Inventor
Amedeo Arturo Failli
Jay Scott Shumsky
Thomas Joseph Caggiano
Joseph Peter Sabatucci
Kevin Anthony Memoli
Eugene John Trybulski
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of DK1377586T3 publication Critical patent/DK1377586T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK02731343T 2001-04-12 2002-04-11 Tricykliske diazepiner som tocolytiske oxytocinreceptorantagonister DK1377586T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28326401P 2001-04-12 2001-04-12

Publications (1)

Publication Number Publication Date
DK1377586T3 true DK1377586T3 (da) 2006-07-10

Family

ID=23085252

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02731343T DK1377586T3 (da) 2001-04-12 2002-04-11 Tricykliske diazepiner som tocolytiske oxytocinreceptorantagonister

Country Status (12)

Country Link
US (1) US7109193B2 (da)
EP (1) EP1377586B1 (da)
JP (1) JP2004526768A (da)
CN (1) CN1273469C (da)
AT (1) ATE321047T1 (da)
BR (1) BR0209014A (da)
CA (1) CA2443490A1 (da)
DE (1) DE60210067T2 (da)
DK (1) DK1377586T3 (da)
ES (1) ES2260434T3 (da)
MX (1) MXPA03009331A (da)
WO (1) WO2002083678A1 (da)

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US7326700B2 (en) * 2001-04-12 2008-02-05 Wyeth Cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
US7202239B2 (en) * 2001-04-12 2007-04-10 Wyeth Cyclohexylphenyl carboxamides tocolytic oxytocin receptor antagonists
US6903087B2 (en) 2001-04-12 2005-06-07 Wyeth Pyrido cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
US7064120B2 (en) * 2001-04-12 2006-06-20 Wyeth Tricyclic pyridyl carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists
US6977254B2 (en) * 2001-04-12 2005-12-20 Wyeth Hydroxy cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
US7022699B2 (en) * 2001-04-12 2006-04-04 Wyeth Cyclohexenyl phenyl diazepines vasopressin and oxytocin receptor modulators
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US7119088B2 (en) 2003-02-19 2006-10-10 Pfizer Inc. Triazole compounds useful in therapy
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MX2007014086A (es) * 2005-05-12 2008-02-07 Wyeth Corp Pirrolobenzodiazepinas y derivados de heteroaril, aril y cicloalquilaminocetona como antagonistas de receptor de hormona estimulante del foliculo.
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CN103450077B (zh) 2007-06-08 2016-07-06 满康德股份有限公司 IRE-1α抑制剂
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US10464955B2 (en) 2014-02-28 2019-11-05 Hangzhou Dac Biotech Co., Ltd. Charged linkers and their uses for conjugation
NZ739830A (en) 2015-07-12 2021-12-24 Hangzhou Dac Biotech Co Ltd Bridge linkers for conjugation of cell-binding molecules
US9839687B2 (en) 2015-07-15 2017-12-12 Suzhou M-Conj Biotech Co., Ltd. Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
US20210308277A1 (en) 2016-11-14 2021-10-07 Hangzhou Dac Biotech Co., Ltd. Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers

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Also Published As

Publication number Publication date
EP1377586A1 (en) 2004-01-07
JP2004526768A (ja) 2004-09-02
MXPA03009331A (es) 2004-11-12
EP1377586B1 (en) 2006-03-22
DE60210067D1 (en) 2006-05-11
US7109193B2 (en) 2006-09-19
WO2002083678A1 (en) 2002-10-24
ATE321047T1 (de) 2006-04-15
BR0209014A (pt) 2005-01-11
DE60210067T2 (de) 2006-10-19
CN1273469C (zh) 2006-09-06
CN1501932A (zh) 2004-06-02
US20030008863A1 (en) 2003-01-09
CA2443490A1 (en) 2002-10-24
ES2260434T3 (es) 2006-11-01

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