DK1351703T3 - Anvendelse af et polypeptid omfattende det ekstracellulære domæne af IL-20RA og IL-20RB til behandling af inflammation - Google Patents
Anvendelse af et polypeptid omfattende det ekstracellulære domæne af IL-20RA og IL-20RB til behandling af inflammationInfo
- Publication number
- DK1351703T3 DK1351703T3 DK01970886T DK01970886T DK1351703T3 DK 1351703 T3 DK1351703 T3 DK 1351703T3 DK 01970886 T DK01970886 T DK 01970886T DK 01970886 T DK01970886 T DK 01970886T DK 1351703 T3 DK1351703 T3 DK 1351703T3
- Authority
- DK
- Denmark
- Prior art keywords
- polypeptide
- inflammation
- treatment
- extracellular domain
- seq
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23330500P | 2000-09-15 | 2000-09-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1351703T3 true DK1351703T3 (da) | 2006-11-27 |
Family
ID=22876714
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01970886T DK1351703T3 (da) | 2000-09-15 | 2001-09-13 | Anvendelse af et polypeptid omfattende det ekstracellulære domæne af IL-20RA og IL-20RB til behandling af inflammation |
Country Status (10)
Country | Link |
---|---|
US (2) | US7855269B2 (de) |
EP (2) | EP1803733B1 (de) |
JP (1) | JP4908723B2 (de) |
AT (2) | ATE333888T1 (de) |
AU (1) | AU2001290837A1 (de) |
CA (1) | CA2422033A1 (de) |
DE (2) | DE60141546D1 (de) |
DK (1) | DK1351703T3 (de) |
ES (1) | ES2267814T3 (de) |
WO (1) | WO2002022153A2 (de) |
Families Citing this family (83)
Publication number | Priority date | Publication date | Assignee | Title |
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US5965704A (en) * | 1997-08-05 | 1999-10-12 | Zymogenetics, Inc. | Class two cytokine receptor-11 |
ES2381650T3 (es) * | 2000-08-08 | 2012-05-30 | Zymogenetics, Inc. | Receptores de citoquinas Zcytor11 solubles |
EP1803733B1 (de) * | 2000-09-15 | 2010-03-10 | ZymoGenetics, Inc. | Polypeptide enthaltend extrazellulären Domäne von IL-20RA und/oderr IL-20RB |
KR20110091598A (ko) * | 2003-03-24 | 2011-08-11 | 지모제넥틱스, 인코포레이티드 | 항-il-22ra 항체 및 결합 파트너 및 염증에 있어서의 사용 방법 |
US20040248097A1 (en) * | 2003-05-23 | 2004-12-09 | Ming-Shi Chang | Interleukin-20 variants and promoters |
EP2087905A2 (de) | 2003-08-08 | 2009-08-12 | Novo Nordisk A/S | Interleukin-20 zur Behandlung und Diagnose von mit Neovaskularization verbunden Zuständen |
SI1725249T1 (sl) | 2003-11-06 | 2014-04-30 | Seattle Genetics, Inc. | Spojine monometilvalina, sposobne konjugacije na ligande |
EP2143733A1 (de) * | 2003-11-21 | 2010-01-13 | ZymoGenetics, Inc. | Anti-il-20-Rezeptor-Antikörper und Bindungspartner und Verfahren zur Anwendung bei Entzündungen |
EP2286844A3 (de) | 2004-06-01 | 2012-08-22 | Genentech, Inc. | Antikörper-Arzneimittelkonjugate und Verfahren |
WO2006034488A2 (en) | 2004-09-23 | 2006-03-30 | Genentech, Inc. | Cysteine engineered antibodies and conjugates |
US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
PT1812476E (pt) * | 2004-10-22 | 2010-11-08 | Zymogenetics Inc | Anticorpos anti-il-22ra e parceiros de ligação e métodos de utilização no tratamento de inflamações |
AU2006212807A1 (en) * | 2005-02-08 | 2006-08-17 | Zymogenetics, Inc. | Anti-IL-20, anti-IL-22 and anti-IL-22RA antibodies and binding partners and methods of using in inflammation |
US7932055B2 (en) | 2006-06-22 | 2011-04-26 | Novo Nordisk A/S | Soluble heterodimeric CD94/NKG2 receptors fusion proteins |
AU2010292172A1 (en) | 2009-09-09 | 2012-05-03 | Centrose, Llc | Extracellular targeted drug conjugates |
PE20130342A1 (es) | 2010-04-15 | 2013-04-20 | Spirogen Sarl | Pirrolobenzodiacepinas y conjugados de las mismas |
EP2579897A1 (de) | 2010-06-08 | 2013-04-17 | Genentech, Inc. | Cystein-manipulierte antikörper und konjugate |
ES2544608T3 (es) | 2010-11-17 | 2015-09-02 | Genentech, Inc. | Conjugados de anticuerpo y de alaninil-maitansinol |
CA2833212C (en) | 2011-05-12 | 2020-06-09 | Genentech, Inc. | Multiple reaction monitoring lc-ms/ms method to detect therapeutic antibodies in animal samples using framework signature peptides |
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NZ707534A (en) | 2012-10-12 | 2018-08-31 | Adc Therapeutics Sa | Pyrrolobenzodiazepine-antibody conjugates |
MX364328B (es) | 2012-10-12 | 2019-04-23 | Medimmune Ltd | Conjugados del anticuerpo pirrolobenzodiazepina. |
EP2906297B1 (de) | 2012-10-12 | 2017-12-06 | ADC Therapeutics SA | Pyrrolobenzodiazepin-antikörper-konjugate |
NZ707486A (en) | 2012-10-12 | 2018-09-28 | Adc Therapeutics Sa | Pyrrolobenzodiazepine - anti-psma antibody conjugates |
WO2014057114A1 (en) | 2012-10-12 | 2014-04-17 | Adc Therapeutics Sàrl | Pyrrolobenzodiazepine-anti-psma antibody conjugates |
DK2906251T3 (da) | 2012-10-12 | 2017-11-20 | Adc Therapeutics Sa | Pyrrolobenzodiazepin-anti-CD22-antistofkonjugater |
PL2766048T3 (pl) | 2012-10-12 | 2015-05-29 | Medimmune Ltd | Pirolobenzodiazepiny i ich koniugaty |
CA2894959C (en) | 2012-12-21 | 2022-01-11 | Spirogen Sarl | Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases |
CN110452242A (zh) | 2012-12-21 | 2019-11-15 | 麦迪穆有限责任公司 | 吡咯并苯并二氮杂卓及其结合物 |
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CN105142674B (zh) | 2013-03-13 | 2018-11-13 | 麦迪穆有限责任公司 | 吡咯并苯并二氮杂卓和其结合物 |
EA201690195A1 (ru) | 2013-08-12 | 2016-05-31 | Дженентек, Инк. | Конъюгатные соединения антитело-лекарство на основе димера 1-(хлорметил)-2,3-дигидро-1h-бензо[e]индола и способы применения и лечения |
GB201317982D0 (en) | 2013-10-11 | 2013-11-27 | Spirogen Sarl | Pyrrolobenzodiazepines and conjugates thereof |
WO2015052534A1 (en) | 2013-10-11 | 2015-04-16 | Spirogen Sàrl | Pyrrolobenzodiazepine-antibody conjugates |
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CN105873614B (zh) | 2013-12-16 | 2020-10-30 | 基因泰克公司 | 肽模拟化合物及其抗体-药物缀合物 |
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SI3151921T1 (sl) | 2014-06-06 | 2019-12-31 | Bristol-Myers Squibb Company | Protitelesa proti z glukortikoidom induciranim receptorjem za faktor nekroze tumorja(GITR) in njihova uporaba |
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AR101844A1 (es) | 2014-09-12 | 2017-01-18 | Genentech Inc | Anticuerpos y conjugados modificados genéticamente con cisteína |
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JP2017533887A (ja) | 2014-09-17 | 2017-11-16 | ジェネンテック, インコーポレイテッド | ピロロベンゾジアゼピン類及びその抗体ジスルフィドコンジュゲート |
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CN107743586B (zh) | 2015-06-03 | 2021-07-02 | 百时美施贵宝公司 | 用于癌症诊断的抗gitr抗体 |
MA43345A (fr) | 2015-10-02 | 2018-08-08 | Hoffmann La Roche | Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation |
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KR102442736B1 (ko) | 2017-06-14 | 2022-09-16 | 에이디씨 테라퓨틱스 에스에이 | 항-cd19 adc의 투여를 위한 투약량 체제 |
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GB201814281D0 (en) | 2018-09-03 | 2018-10-17 | Femtogenix Ltd | Cytotoxic agents |
EP3870235A1 (de) | 2018-10-24 | 2021-09-01 | F. Hoffmann-La Roche AG | Konjugierte chemische abbauauslöser und verwendungsverfahren |
CN113227119A (zh) | 2018-12-10 | 2021-08-06 | 基因泰克公司 | 用于与含Fc的蛋白质进行位点特异性缀合的光交联肽 |
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-
2001
- 2001-09-13 EP EP05028379A patent/EP1803733B1/de not_active Expired - Lifetime
- 2001-09-13 AT AT01970886T patent/ATE333888T1/de active
- 2001-09-13 DE DE60141546T patent/DE60141546D1/de not_active Expired - Lifetime
- 2001-09-13 JP JP2002526403A patent/JP4908723B2/ja not_active Expired - Fee Related
- 2001-09-13 AT AT05028379T patent/ATE460429T1/de not_active IP Right Cessation
- 2001-09-13 ES ES01970886T patent/ES2267814T3/es not_active Expired - Lifetime
- 2001-09-13 US US09/951,268 patent/US7855269B2/en not_active Expired - Fee Related
- 2001-09-13 AU AU2001290837A patent/AU2001290837A1/en not_active Abandoned
- 2001-09-13 CA CA002422033A patent/CA2422033A1/en not_active Abandoned
- 2001-09-13 DK DK01970886T patent/DK1351703T3/da active
- 2001-09-13 EP EP01970886A patent/EP1351703B1/de not_active Expired - Lifetime
- 2001-09-13 WO PCT/US2001/028557 patent/WO2002022153A2/en active IP Right Grant
- 2001-09-13 DE DE60121808T patent/DE60121808T2/de not_active Expired - Lifetime
-
2010
- 2010-11-09 US US12/942,302 patent/US20110077207A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE60121808T2 (de) | 2007-03-29 |
EP1351703B1 (de) | 2006-07-26 |
JP2004525074A (ja) | 2004-08-19 |
EP1351703A2 (de) | 2003-10-15 |
DE60121808D1 (de) | 2006-09-07 |
ATE333888T1 (de) | 2006-08-15 |
WO2002022153A3 (en) | 2003-06-19 |
EP1803733A2 (de) | 2007-07-04 |
JP4908723B2 (ja) | 2012-04-04 |
AU2001290837A1 (en) | 2002-03-26 |
ATE460429T1 (de) | 2010-03-15 |
US20020085992A1 (en) | 2002-07-04 |
WO2002022153A2 (en) | 2002-03-21 |
US7855269B2 (en) | 2010-12-21 |
DE60141546D1 (de) | 2010-04-22 |
US20110077207A1 (en) | 2011-03-31 |
ES2267814T3 (es) | 2007-03-16 |
EP1803733B1 (de) | 2010-03-10 |
EP1803733A3 (de) | 2007-10-31 |
CA2422033A1 (en) | 2002-03-21 |
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