DK1078001T3 - IL-6 antagonost peptider - Google Patents

IL-6 antagonost peptider

Info

Publication number
DK1078001T3
DK1078001T3 DK99926326T DK99926326T DK1078001T3 DK 1078001 T3 DK1078001 T3 DK 1078001T3 DK 99926326 T DK99926326 T DK 99926326T DK 99926326 T DK99926326 T DK 99926326T DK 1078001 T3 DK1078001 T3 DK 1078001T3
Authority
DK
Denmark
Prior art keywords
seq
present
antagonist peptides
peptide
peptides
Prior art date
Application number
DK99926326T
Other languages
English (en)
Inventor
Ottaviano Serlupi-Crescenzi
Pietra Linda Della
Alessandro Bressan
Anna Rita Pezzotti
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Application granted granted Critical
Publication of DK1078001T3 publication Critical patent/DK1078001T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5412—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DK99926326T 1998-05-18 1999-05-18 IL-6 antagonost peptider DK1078001T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98108997A EP0972780A1 (en) 1998-05-18 1998-05-18 Il-6 antagonist peptides
PCT/EP1999/003421 WO1999060013A2 (en) 1998-05-18 1999-05-18 Il-6 antagonist peptides

Publications (1)

Publication Number Publication Date
DK1078001T3 true DK1078001T3 (da) 2007-02-19

Family

ID=8231951

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99926326T DK1078001T3 (da) 1998-05-18 1999-05-18 IL-6 antagonost peptider

Country Status (14)

Country Link
US (2) US6599875B1 (da)
EP (2) EP0972780A1 (da)
JP (1) JP4468578B2 (da)
AT (1) ATE347563T1 (da)
AU (1) AU749616B2 (da)
CA (2) CA2690399C (da)
CY (1) CY1105865T1 (da)
DE (1) DE69934308T2 (da)
DK (1) DK1078001T3 (da)
ES (1) ES2273492T3 (da)
IL (2) IL139575A0 (da)
PT (1) PT1078001E (da)
SI (1) SI1078001T1 (da)
WO (1) WO1999060013A2 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0972780A1 (en) * 1998-05-18 2000-01-19 Applied Research Systems ARS Holding N.V. Il-6 antagonist peptides
CA2346996C (en) 1998-10-23 2013-11-19 Amgen Inc. Dimeric thrombopoietin peptide mimetics binding to mp1 receptor and having thrombopoietic activity
US7488590B2 (en) 1998-10-23 2009-02-10 Amgen Inc. Modified peptides as therapeutic agents
US8143380B2 (en) 2004-07-08 2012-03-27 Amgen Inc. Therapeutic peptides
US20070036788A1 (en) * 2004-09-22 2007-02-15 Ahmed Sheriff Use of a compound for reducing the biological effectiveness of il-6
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
CA2648644C (en) 2006-04-07 2016-01-05 Osaka University Muscle regeneration promoter
US9283260B2 (en) 2006-04-21 2016-03-15 Amgen Inc. Lyophilized therapeutic peptibody formulations
BRPI0806812B8 (pt) 2007-01-23 2021-09-14 Chugai Pharmaceutical Co Ltd Agente para suprimir reação de rejeição crônica e uso de um inibidor de il-6
TWI528973B (zh) 2008-06-05 2016-04-11 Chugai Pharmaceutical Co Ltd Nerve infiltration inhibitor
EP2361096B1 (en) 2008-11-25 2019-01-02 AlderBio Holdings LLC Il-6-specific antibody to prevent or treat cachexia
EP2578231B1 (en) 2010-05-28 2022-10-26 Chugai Seiyaku Kabushiki Kaisha Antitumor t cell response enhancer
CA2818814A1 (en) 2010-11-23 2012-05-31 Alder Biopharmaceuticals, Inc. Anti-il-6 antibodies for the treatment of anemia
RS60050B1 (sr) 2011-01-18 2020-04-30 Bioniz Llc Kompozicije za modulaciju aktivnosti gama-c-citokina
WO2013063229A1 (en) 2011-10-25 2013-05-02 The Regents Of The University Of Michigan Her2 targeting agent treatment in non-her2-amplified cancers having her2 expressing cancer stem cells
US9959384B2 (en) 2013-12-10 2018-05-01 Bioniz, Llc Methods of developing selective peptide antagonists
CN103923182A (zh) * 2014-01-17 2014-07-16 南通诚信氨基酸有限公司 白介素-6多肽抑制剂及其应用
WO2017062685A1 (en) 2015-10-09 2017-04-13 Bioniz, Llc Modulating gamma - c -cytokine activity
EP3620531A4 (en) 2017-05-02 2021-03-17 National Center of Neurology and Psychiatry METHOD OF PREDICTION AND EVALUATION OF THERAPEUTIC EFFECT IN DISEASES RELATING TO IL-6 AND NEUTROPHILS
JP7235249B2 (ja) 2017-10-20 2023-03-08 学校法人兵庫医科大学 抗ｉｌ－６受容体抗体を含有する術後の癒着を抑制するための医薬組成物
WO2020201362A2 (en) 2019-04-02 2020-10-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods of predicting and preventing cancer in patients having premalignant lesions
CN116003530B (zh) * 2022-12-27 2023-12-15 西湖大学 一种针对白细胞介素-6的d-蛋白抑制剂及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4420782C1 (de) * 1994-06-15 1995-08-17 Fluegge Ulf Ingo Prof Dr DNA-Sequenz, kodierend einen 2-Oxoglutarat/Malat-Translokator, Plasmide, Bakterien, Hefen und Pflanzen enthaltend diesen Transporter
AU3719395A (en) * 1994-09-21 1996-04-09 Cytogen Corporation Antigen binding peptides (abtides) from peptide libraries
AU3204895A (en) * 1995-02-01 1996-08-21 University Of Massachusetts Medical Center Methods of selecting a random peptide that binds to a target protein
CA2220433C (en) * 1995-05-11 2010-02-16 Applied Research Systems Ars Holding N.V. Il-6 activity inhibitor
AU6731896A (en) * 1995-07-17 1997-02-18 Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V. Cyclitol
DK0852587T3 (da) * 1995-09-28 2009-06-08 Yeda Res & Dev Syntetiske peptider der inhiberer IL-6-aktivitet
EP0928293A1 (en) * 1996-06-20 1999-07-14 Koster, Henk W. Il-6 and il-6-receptor derived peptides having il-6 antagonistic or agonistic activity
EP0972780A1 (en) * 1998-05-18 2000-01-19 Applied Research Systems ARS Holding N.V. Il-6 antagonist peptides

Also Published As

Publication number Publication date
CA2332817C (en) 2010-08-31
ES2273492T3 (es) 2007-05-01
EP0972780A1 (en) 2000-01-19
ATE347563T1 (de) 2006-12-15
SI1078001T1 (sl) 2007-04-30
CA2332817A1 (en) 1999-11-25
EP1078001B1 (en) 2006-12-06
IL139575A (en) 2008-03-20
JP4468578B2 (ja) 2010-05-26
IL139575A0 (en) 2002-02-10
AU4362799A (en) 1999-12-06
CY1105865T1 (el) 2011-02-02
JP2002527354A (ja) 2002-08-27
AU749616B2 (en) 2002-06-27
WO1999060013A3 (en) 2000-03-09
US20030186876A1 (en) 2003-10-02
CA2690399A1 (en) 1999-11-25
CA2690399C (en) 2015-01-20
DE69934308T2 (de) 2007-03-29
US6838433B2 (en) 2005-01-04
EP1078001A2 (en) 2001-02-28
WO1999060013A2 (en) 1999-11-25
PT1078001E (pt) 2007-01-31
DE69934308D1 (de) 2007-01-18
US6599875B1 (en) 2003-07-29

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