DK1066056T4 - Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernmangel, fremgangsmåde til fremstilling af jerndextranforbindelsen og anvendelse af denne forbindelse til fremstilling af et... - Google Patents

Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernmangel, fremgangsmåde til fremstilling af jerndextranforbindelsen og anvendelse af denne forbindelse til fremstilling af et...

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Publication number
DK1066056T4
DK1066056T4 DK99908785T DK99908785T DK1066056T4 DK 1066056 T4 DK1066056 T4 DK 1066056T4 DK 99908785 T DK99908785 T DK 99908785T DK 99908785 T DK99908785 T DK 99908785T DK 1066056 T4 DK1066056 T4 DK 1066056T4
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DK
Denmark
Prior art keywords
compound
iron
iron dextran
prevention
preparing
Prior art date
Application number
DK99908785T
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English (en)
Other versions
DK1066056T3 (da
Inventor
Lars Christensen
Hans Berg Andreasen
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Pharmacosmos Holding As
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Application filed by Pharmacosmos Holding As filed Critical Pharmacosmos Holding As
Application granted granted Critical
Publication of DK1066056T3 publication Critical patent/DK1066056T3/da
Publication of DK1066056T4 publication Critical patent/DK1066056T4/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK99908785T 1998-03-25 1999-03-24 Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernmangel, fremgangsmåde til fremstilling af jerndextranforbindelsen og anvendelse af denne forbindelse til fremstilling af et... DK1066056T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK199800420A DK172860B1 (da) 1998-03-25 1998-03-25 Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman
PCT/DK1999/000160 WO1999048533A1 (en) 1998-03-25 1999-03-24 An iron-dextran compound for use as a component in a therapeutical composition for prophylaxis or treatment of iron-deficiency, a process for producing said iron-dextran compound and use of said compound for the preparation of a parenterally administrable therapeutical composition

Publications (2)

Publication Number Publication Date
DK1066056T3 DK1066056T3 (da) 2002-10-14
DK1066056T4 true DK1066056T4 (da) 2009-04-14

Family

ID=8093321

Family Applications (2)

Application Number Title Priority Date Filing Date
DK199800420A DK172860B1 (da) 1998-03-25 1998-03-25 Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman
DK99908785T DK1066056T4 (da) 1998-03-25 1999-03-24 Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernmangel, fremgangsmåde til fremstilling af jerndextranforbindelsen og anvendelse af denne forbindelse til fremstilling af et...

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK199800420A DK172860B1 (da) 1998-03-25 1998-03-25 Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman

Country Status (28)

Country Link
US (1) US6291440B1 (da)
EP (1) EP1066056B2 (da)
JP (1) JP4558198B2 (da)
KR (1) KR100612071B1 (da)
CN (1) CN1147322C (da)
AR (1) AR015738A1 (da)
AT (1) ATE220560T1 (da)
AU (1) AU740432B2 (da)
BR (1) BRPI9908914B8 (da)
CA (1) CA2322633C (da)
CZ (1) CZ300823B6 (da)
DE (1) DE69902154T3 (da)
DK (2) DK172860B1 (da)
EA (1) EA003427B1 (da)
ES (1) ES2180279T5 (da)
HK (1) HK1033426A1 (da)
HU (1) HU228483B1 (da)
ID (1) ID26778A (da)
NO (1) NO329591B1 (da)
NZ (1) NZ505983A (da)
PL (1) PL195582B1 (da)
PT (1) PT1066056E (da)
SI (1) SI1066056T2 (da)
SK (1) SK284499B6 (da)
TR (1) TR200002733T2 (da)
UA (1) UA70939C2 (da)
WO (1) WO1999048533A1 (da)
ZA (1) ZA200004016B (da)

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DK173138B1 (da) * 1998-11-20 2000-02-07 Pharmacosmos Holding As Fremgangsmåde til fremstilling af en jerndextranforbindelse, jerndextranforbindelse fremstillet efter fremgangsmåden, farma
US7871597B2 (en) 1999-04-09 2011-01-18 Amag Pharmaceuticals, Inc. Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents
WO2000061191A2 (en) * 1999-04-09 2000-10-19 Advanced Magnetics, Inc. Heat stable coated colloidal iron oxides
KR20020003344A (ko) * 2001-12-17 2002-01-12 유형선 철분 보급제 경구 투여 제제 조성물
NZ535761A (en) * 2002-04-09 2007-09-28 Pharmacosmos Holding As Iron dextrin compounds for the treatment of iron deficiency anaemia
DE10249552A1 (de) 2002-10-23 2004-05-13 Vifor (International) Ag Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel
US20060116349A1 (en) * 2003-03-14 2006-06-01 Luitpold Pharmaceuticals, Inc. Methods and compositions for administration of iron for the treatment of restless leg syndrome
DE102004031181A1 (de) * 2004-06-28 2006-01-19 Vifor (International) Ag Phosphatadsorbens
ITMO20050056A1 (it) * 2005-03-15 2006-09-16 Biofer Spa Processo per la preparazione di complessi del ferro trivalente con zuccheri mono-, di- e polisaccaridi.
EP1757299A1 (de) 2005-08-25 2007-02-28 Vifor (International) Ag Eisen(III)-Komplexverbindungen zur Behandlung von Eisenmangel-Zuständen bei Patienten mit chronisch-entzündlicher Darmerkrankung
CA2635894C (en) 2006-01-06 2017-09-12 Luitpold Pharmaceuticals, Inc. Methods and compositions for administration of iron
EP1947120A1 (de) * 2007-01-19 2008-07-23 Vifor (International) Ag Eisen-Kohlenhydrat-Komplex-Verbindungen
EP1997833A1 (de) * 2007-05-29 2008-12-03 Vifor (International) Ag Wasserlösliche Eisen-Kohlenhydratderivat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel
CN101585887B (zh) * 2008-05-22 2011-12-14 中国科学院过程工程研究所 应用纳滤技术对右旋糖酐铁络合物水溶液进行脱盐和浓缩的方法
CA2756580A1 (en) * 2009-03-25 2010-09-30 Hans Andreasen A stable iron oligosaccharide compound
CN101967205B (zh) * 2010-10-12 2013-04-17 滨州学院 一种β-葡聚糖铁复合物及其制备方法
EP2537866A1 (en) 2011-06-21 2012-12-26 Serumwerk Bernburg AG Hydroxyethyl starch derivatives, method for manufacturing the same and therapeutical uses thereof
PL398814A1 (pl) 2012-04-16 2013-10-28 Uniwersytet Jagiellonski Zastosowanie pochodnych dekstranu do przeciwdzialania lub leczenia niedokrwistosci
US10172882B2 (en) 2014-06-22 2019-01-08 Dexcel Pharma Technologies Ltd. Pharmaceutical compositions comprising ferric citrate and methods for the production thereof
US11040059B2 (en) * 2014-10-27 2021-06-22 Pharmacosmos Holding A/S Treatment or prevention of anaemia in pregnant non-human mammals
KR20200044030A (ko) * 2017-09-11 2020-04-28 파르마코스모스 홀딩 에이/에스 치료용 철 착화합물
CN109646454A (zh) * 2018-12-29 2019-04-19 博瑞生物医药(苏州)股份有限公司 异麦芽糖酐铁1000的制备方法
CN110183548B (zh) * 2019-06-28 2021-05-18 瑞普(天津)生物药业有限公司 一种低分子葡聚糖铁的制备方法及其应用
AU2022323733A1 (en) 2021-08-03 2024-02-29 Pharmacosmos Holding A/S Iron complex compounds for subcutaneous use in therapy of iron deficiency in companion animals

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USRE24642E (en) 1959-04-28 Therapeutic preparations of iron
DK117730A (da)
US2885393A (en) 1956-02-24 1959-05-05 R K Laros Company Dextran-iron complex and process for making same
US3093545A (en) 1960-08-29 1963-06-11 Armour Pharma Therapeutic iron-dextran preparations
US3234209A (en) * 1963-09-13 1966-02-08 Chemicals Inc Process for making iron hydrogenated dextran
DE1293144B (de) * 1964-11-04 1969-04-24 Hausmann Ag Labor Verfahren zur Herstellung von Komplexverbindungen des Eisens mit Sorbit, Gluconsaeure und einem Oligosaccharid
GB1183940A (en) 1966-10-22 1970-03-11 Fisons Pharmaceuticals Ltd Ferric Hydroxide Complexes
GB1200902A (en) 1967-05-13 1970-08-05 Fisons Pharmaceuticals Ltd Iron-dextran complexes
CH507993A (de) 1967-07-13 1971-05-31 Kutnowskie Zakl Farma Verfahren zur Herstellung von Eisen(III)-komplexverbindungen mit hydriertem Dextran
DK129353B (da) 1968-04-29 1974-09-30 Fisons Pharmaceuticals Ltd Analogifremgangsmåde til fremstilling af et ferrihydroxid-dextranderivatkompleks eller en opløsning deraf.
US3697502A (en) 1969-11-03 1972-10-10 Christensen Henry M Method of making iron dextran-preparations
GB1562913A (en) * 1976-06-16 1980-03-19 Fisons Ltd Fractionating fluid mixtures of dextrans
DE3422249A1 (de) * 1984-06-15 1985-12-19 Pfeifer & Langen, 5000 Köln Wasserloesliches eisendextran und verfahren zu seiner herstellung
US5102652A (en) * 1986-07-03 1992-04-07 Advanced Magnetics Inc. Low molecular weight carbohydrates as additives to stabilize metal oxide compositions
US4827945A (en) 1986-07-03 1989-05-09 Advanced Magnetics, Incorporated Biologically degradable superparamagnetic materials for use in clinical applications
IT1263831B (it) * 1993-01-29 1996-09-04 Paolo Chiesi Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo basico, un acido ed una ciclodestrina
RU2093577C1 (ru) * 1993-11-04 1997-10-20 Государственный институт кровезаменителей и медицинских препаратов Способ получения декстрана
GB9402029D0 (en) * 1994-02-03 1994-03-30 Smithkline Beecham Plc Novel formulation
US5624668A (en) * 1995-09-29 1997-04-29 Luitpold Pharmaceuticals, Inc. Iron dextran formulations

Also Published As

Publication number Publication date
EA200000981A1 (ru) 2001-02-26
NO329591B1 (no) 2010-11-15
HK1033426A1 (en) 2001-08-31
EP1066056A1 (en) 2001-01-10
JP4558198B2 (ja) 2010-10-06
PL343164A1 (en) 2001-07-30
ES2180279T5 (es) 2009-05-05
TR200002733T2 (tr) 2000-12-21
PL195582B1 (pl) 2007-10-31
KR100612071B1 (ko) 2006-08-11
DE69902154D1 (de) 2002-08-22
AR015738A1 (es) 2001-05-16
ZA200004016B (en) 2001-07-25
DE69902154T3 (de) 2009-07-09
CA2322633A1 (en) 1999-09-30
ID26778A (id) 2001-02-08
AU740432B2 (en) 2001-11-01
BRPI9908914B1 (pt) 2012-06-12
EP1066056B1 (en) 2002-07-17
EP1066056B2 (en) 2008-12-10
SI1066056T1 (en) 2002-12-31
NO20004151L (no) 2000-08-18
PT1066056E (pt) 2002-12-31
BRPI9908914A (pt) 2000-11-21
DK172860B1 (da) 1999-08-16
AU2827399A (en) 1999-10-18
CA2322633C (en) 2009-01-27
HUP0101189A2 (hu) 2001-08-28
UA70939C2 (uk) 2004-11-15
CN1293577A (zh) 2001-05-02
HU228483B1 (en) 2013-03-28
DK42099A (da) 1999-08-16
SK14092000A3 (sk) 2001-04-09
DE69902154T2 (de) 2003-03-06
EA003427B1 (ru) 2003-04-24
HUP0101189A3 (en) 2003-12-29
JP2002507582A (ja) 2002-03-12
US6291440B1 (en) 2001-09-18
KR20010034641A (ko) 2001-04-25
BRPI9908914B8 (pt) 2021-07-06
NZ505983A (en) 2002-11-26
CN1147322C (zh) 2004-04-28
SI1066056T2 (sl) 2009-04-30
CZ20003535A3 (cs) 2001-04-11
ATE220560T1 (de) 2002-08-15
ES2180279T3 (es) 2003-02-01
CZ300823B6 (cs) 2009-08-19
NO20004151D0 (no) 2000-08-18
SK284499B6 (sk) 2005-05-05
DK1066056T3 (da) 2002-10-14
WO1999048533A1 (en) 1999-09-30

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