DK105082A - Fremgangsmaade til fremstilling af substituerede trifluormethylphenyl-tetrahydropyridiner - Google Patents

Fremgangsmaade til fremstilling af substituerede trifluormethylphenyl-tetrahydropyridiner Download PDF

Info

Publication number: DK105082A
Authority: DK; Denmark
Prior art keywords: trifluormethylphenyl; tetrahydropyridines; preparing substituted; substituted; preparing
Prior art date: 1981-03-11

Application number

DK105082A

Other languages

English (en)

Other versions

DK152843C (da

DK152843B (da

Inventor

D Nisato

E Crisafulli

A Bianchetti

P Carminati

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-03-11

Filing date

1982-03-10

Publication date

1982-09-12

1982-03-10 Application filed by Sanofi Sa filed Critical Sanofi Sa

1982-09-12 Publication of DK105082A publication Critical patent/DK105082A/da

1988-05-24 Publication of DK152843B publication Critical patent/DK152843B/da

1988-10-03 Application granted granted Critical

1988-10-03 Publication of DK152843C publication Critical patent/DK152843C/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Child & Adolescent Psychology (AREA)
Hematology (AREA)
Obesity (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK105082A 1981-03-11 1982-03-10 Analogifremgangsmaade til fremstilling af n-substituerede 4-(3-trifluormethylphenyl)-1,2,3,6-tetrahydropyridiner og farmaceutisk acceptable salte deraf DK152843C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8104890		1981-03-11
FR8104890A FR2501682A1 (fr)	1981-03-11	1981-03-11	Trifluoromethylphenylpyridines a activite anorexigene, un procede de preparation et compositions pharmaceutiques en contenant

Publications (3)

Publication Number	Publication Date
DK105082A true DK105082A (da)	1982-09-12
DK152843B DK152843B (da)	1988-05-24
DK152843C DK152843C (da)	1988-10-03

Family

ID=9256120

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK105082A DK152843C (da)	1981-03-11	1982-03-10	Analogifremgangsmaade til fremstilling af n-substituerede 4-(3-trifluormethylphenyl)-1,2,3,6-tetrahydropyridiner og farmaceutisk acceptable salte deraf

Country Status (20)

Country	Link
US (2)	US4472408A (da)
EP (1)	EP0060176B1 (da)
JP (1)	JPS57159766A (da)
AR (2)	AR229174A1 (da)
AT (1)	ATE11044T1 (da)
AU (1)	AU547692B2 (da)
CA (1)	CA1196643A (da)
DE (1)	DE3261731D1 (da)
DK (1)	DK152843C (da)
ES (3)	ES510302A0 (da)
FI (1)	FI76786C (da)
FR (1)	FR2501682A1 (da)
GR (1)	GR79178B (da)
IE (1)	IE52365B1 (da)
IL (1)	IL65169A0 (da)
NO (1)	NO158736C (da)
NZ (1)	NZ199973A (da)
PT (1)	PT74559B (da)
YU (2)	YU50782A (da)
ZA (1)	ZA821518B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2531707A1 (fr) *	1982-08-16	1984-02-17	Midy Spa	Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques
DE3438394A1 (de) *	1984-10-19	1986-04-30	Merck Patent Gmbh, 6100 Darmstadt	Pyridinderivate
HU198454B (en) *	1987-12-14	1989-10-30	Richter Gedeon Vegyeszet	Process for production of new derivatives of tetrahydrospiridin and medical compositions containing these compounds
FR2639226B1 (fr) *	1988-11-18	1993-11-05	Sanofi	Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles anxio-depressifs
FR2650505B1 (fr) *	1989-08-07	1994-06-03	Midy Spa	Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale
FR2672213B1 (fr) *	1991-02-05	1995-03-10	Sanofi Sa	Utilisation de derives 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridiniques comme capteurs de radicaux libres.

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3125488A (en) *		1964-03-17		Method of inducing analgesia by
US3072648A (en) *		1963-01-08		X-phenyl-s
GB881894A (en) *	1958-04-22	1961-11-08	Paul Adriaan Jan Janssen	Tetrahydropyridine derivatives
GB948071A (en) *	1959-05-01	1964-01-29	May & Baker Ltd	New heterocyclic compounds
FR86403E (fr) *	1959-05-01	1966-02-04	May & Baker Ltd	Nouveaux dérivés de la phényl-4 pipéridine et leur préparation
GB984364A (en) *	1961-07-28	1965-02-24	May & Baker Ltd	Substituted piperidines and tetrahydropyridines
US3284457A (en) *	1964-01-17	1966-11-08	Degussa	1-lower alkyl-4-substituted phenyl-1, 2, 3, 6-tetrahydropyridines and acid addition salts
US3626066A (en) *	1967-12-13	1971-12-07	Robins Co Inc A H	Arylpyridinyl-alkyl alcohol derivatives in compositions and methods for tranquilizing mammals
AT287711B (de) *	1968-06-25	1971-02-10	Boehringer Sohn Ingelheim	Verfahren zur Herstellung von neuen 1-Alkyl-1,2,5,6-tetrahydro-3-pyridylmethyl-carbonsäureestern sowie deren Säureadditionssalzen und quaternären Ammoniumverbindungen
DE2101997A1 (en) *	1971-01-16	1972-08-03	Farbenfabriken Bayer AG, 509öfLeverkusen	1-benzyl-4-subst-tetrahydropyridines - useful as intermediates for pharmaceuticals
US4024151A (en) *	1975-09-29	1977-05-17	E. R. Squibb & Sons, Inc.	4-Phenylpiperidinyl (and 4-phenyl-tetrahydropyridinyl) alkylamino-oxoalkanoic acids
US4012374A (en) *	1975-09-29	1977-03-15	E. R. Squibb & Sons, Inc.	1-[[4-Phenyl-piperidinyl (or tetrahydropyridinyl)]alkyl]-2,6-piperidinedione and analogs
FR2416886A1 (fr) *	1978-02-08	1979-09-07	Roussel Uclaf	Nouveaux derives de la 3-phenyl-tetrahydropyridine et leurs sels, procedes de preparation et application a titre de medicaments

1981
- 1981-03-11 FR FR8104890A patent/FR2501682A1/fr active Granted
1982
- 1982-02-24 AT AT82400320T patent/ATE11044T1/de not_active IP Right Cessation
- 1982-02-24 EP EP82400320A patent/EP0060176B1/fr not_active Expired
- 1982-02-24 DE DE8282400320T patent/DE3261731D1/de not_active Expired
- 1982-03-01 IE IE455/82A patent/IE52365B1/en not_active IP Right Cessation
- 1982-03-03 US US06/354,522 patent/US4472408A/en not_active Expired - Lifetime
- 1982-03-04 AU AU81111/82A patent/AU547692B2/en not_active Ceased
- 1982-03-04 GR GR67477A patent/GR79178B/el unknown
- 1982-03-04 IL IL65169A patent/IL65169A0/xx not_active IP Right Cessation
- 1982-03-08 ZA ZA821518A patent/ZA821518B/xx unknown
- 1982-03-09 YU YU00507/82A patent/YU50782A/xx unknown
- 1982-03-10 DK DK105082A patent/DK152843C/da not_active IP Right Cessation
- 1982-03-10 FI FI820826A patent/FI76786C/fi not_active IP Right Cessation
- 1982-03-10 PT PT74559A patent/PT74559B/pt not_active IP Right Cessation
- 1982-03-10 AR AR288693A patent/AR229174A1/es active
- 1982-03-10 NO NO820767A patent/NO158736C/no unknown
- 1982-03-10 NZ NZ199973A patent/NZ199973A/en unknown
- 1982-03-10 ES ES510302A patent/ES510302A0/es active Granted
- 1982-03-11 JP JP57037338A patent/JPS57159766A/ja active Granted
- 1982-03-11 CA CA000398149A patent/CA1196643A/en not_active Expired
- 1982-11-26 AR AR291420A patent/AR228330A1/es active
- 1982-12-23 ES ES518545A patent/ES518545A0/es active Granted
1983
- 1983-11-22 ES ES527456A patent/ES8407023A1/es not_active Expired
1984
- 1984-07-16 US US06/630,969 patent/US4602024A/en not_active Expired - Lifetime
- 1984-11-21 YU YU01954/84A patent/YU195484A/xx unknown

Also Published As

Publication number	Publication date
FI76786C (fi)	1988-12-12
NO158736C (no)	1988-10-26
FI820826L (fi)	1982-09-12
NO158736B (no)	1988-07-18
GR79178B (da)	1984-10-02
DE3261731D1 (en)	1985-02-14
AU8111182A (en)	1982-09-16
US4472408A (en)	1984-09-18
ES527456A0 (es)	1984-09-01
NZ199973A (en)	1984-10-19
ES8407023A1 (es)	1984-09-01
ES8305329A1 (es)	1983-04-01
PT74559B (fr)	1983-11-10
JPS57159766A (en)	1982-10-01
EP0060176A1 (fr)	1982-09-15
YU50782A (en)	1985-03-20
DK152843C (da)	1988-10-03
IE820455L (en)	1982-09-11
ES8403109A1 (es)	1984-03-01
YU195484A (en)	1985-03-20
FR2501682A1 (fr)	1982-09-17
US4602024A (en)	1986-07-22
CA1196643A (en)	1985-11-12
ATE11044T1 (de)	1985-01-15
IE52365B1 (en)	1987-09-30
ES518545A0 (es)	1984-03-01
JPH0435459B2 (da)	1992-06-11
AR228330A1 (es)	1983-02-15
FI76786B (fi)	1988-08-31
NO820767L (no)	1982-09-13
ES510302A0 (es)	1983-04-01
AR229174A1 (es)	1983-06-30
FR2501682B1 (da)	1984-03-16
ZA821518B (en)	1983-01-26
AU547692B2 (en)	1985-10-31
IL65169A0 (en)	1982-05-31
EP0060176B1 (fr)	1985-01-02
PT74559A (fr)	1982-04-01
DK152843B (da)	1988-05-24

Legal Events

Date	Code	Title	Description
1994-11-21	PBP	Patent lapsed

Publication	Publication Date	Title
DK350083A (da)	1984-02-11	Fremgangsmaade til fremstilling af phenylethanolaminer
DK434381A (da)	1982-04-03	Fremgangsmaade til fremstilling af substituerede imonodicarboxylsyrer
DK280182A (da)	1982-12-24	Fremgangsmaade til fremstilling af n-aryl-piperazinalkanamider
DK417981A (da)	1982-03-23	Fremgangsmaade til fremstilling af 3-aryl-5-isothiazol-derivater
DK88081A (da)	1981-08-30	Fremgangsmaade til fremstilling af tetrazolderivater
DK343682A (da)	1983-02-04	Fremgangsmaade til fremstilling af thiazolidinylalkylen-piperazin-derivater
DK416082A (da)	1983-03-19	Fremgangsmaade til fremstilling af aminopropanolderivater af 2-hydroxy-beta-phenylpropiophenoner
DK357782A (da)	1983-02-11	Fremgangsmaade til fremstilling af tetrahydrofurancarboxylsyrederivater
DK479981A (da)	1982-05-01	Fremgangsmaade til fremstilling af 3-aryl-3-hydroxyphthalimidiner
DK460182A (da)	1983-04-17	Fremgangsmaade til fremstilling af staphylokinase
DK370582A (da)	1983-02-20	Fremgangsmaade til fremstilling af 2-beta-d-ribofuranosylthiazol-4-carboxamid
DK355584D0 (da)	1984-07-20	Fremgangsmaade til fremstilling af 3-exomethylen-cephalosporiner
DK343782A (da)	1983-02-04	Fremgangsmaade til fremstilling af spirothiazolidinyl-piperazin-derivater
DK40883A (da)	1983-08-04	Fremgangsmaade til fremstilling af benzothienylallylaminer
DK424083D0 (da)	1983-09-16	Fremgangsmade til fremstilling af anthracyclinglycosider
DK105082A (da)	1982-09-12	Fremgangsmaade til fremstilling af substituerede trifluormethylphenyl-tetrahydropyridiner
DK501582A (da)	1983-05-12	Fremgangsmaade til fremstilling af acylcyanider
DK548081A (da)	1982-06-12	Fremgangsmaade til fremstilling af buspiron
DK518883D0 (da)	1983-11-14	Fremgangsmade til fremstilling af 1-oxa-beta-lactam-forbindelser
DK385983A (da)	1984-02-25	Fremgangsmaade til fremstilling af 1-oxacephamer
DK219483D0 (da)	1983-05-17	Fremgangsmade til fremstilling af anthracyclinglycosider
DK212884A (da)	1984-10-30	Fremgangsmaade til fremstilling af isoxazolylimidazolidinoner
DK329685A (da)	1986-02-02	Fremgangsmaade til fremstilling af alfa-l-aspartyl-l-phenylalaninalkylestere
DK252482A (da)	1982-12-06	Fremgangsmaade til fremstilling af substituerede phenolethere af 2-hydroxy-3-dialkylaminopropanol
DK432683A (da)	1984-03-28	Fremgangsmaade til fremstilling af 2-hydroxy-2-phenylethylaminer