DK1031575T3 - Fremgangsmåde til fremstilling af væksthormonsekretionsfremkaldende midler - Google Patents

Fremgangsmåde til fremstilling af væksthormonsekretionsfremkaldende midler

Info

Publication number: DK1031575T3
Authority: DK; Denmark
Prior art keywords: preparation; growth hormone; hormone secretion; inducers; secretion inducers
Prior art date: 1999-02-26

Application number

DK00301526T

Other languages

English (en)

Inventor

Frank Robert Busch

Charles Kwok-Fung Chiu

Clifford Nathaniel Meltz

Ronald James Post

Peter Robert Rose

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-02-26

Filing date

2000-02-25

Publication date

2005-01-03

2000-02-25 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2005-01-03 Application granted granted Critical

2005-01-03 Publication of DK1031575T3 publication Critical patent/DK1031575T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

DK00301526T 1999-02-26 2000-02-25 Fremgangsmåde til fremstilling af væksthormonsekretionsfremkaldende midler DK1031575T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US12274599P	1999-02-26	1999-02-26
EP00301526A EP1031575B1 (en)	1999-02-26	2000-02-25	Process for preparing growth hormone secretagogues

Publications (1)

Publication Number	Publication Date
DK1031575T3 true DK1031575T3 (da)	2005-01-03

Family

ID=22404505

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00301526T DK1031575T3 (da)	1999-02-26	2000-02-25	Fremgangsmåde til fremstilling af væksthormonsekretionsfremkaldende midler

Country Status (44)

Country	Link
US (2)	US6541634B2 (da)
EP (2)	EP1449842A1 (da)
JP (3)	JP3437813B2 (da)
KR (2)	KR100372063B1 (da)
CN (3)	CN1837205A (da)
AP (1)	AP1221A (da)
AR (2)	AR029617A1 (da)
AT (1)	ATE277944T1 (da)
AU (1)	AU764122B2 (da)
BG (1)	BG104175A (da)
BR (2)	BRPI0017522B8 (da)
CA (1)	CA2299495C (da)
CO (1)	CO5160252A1 (da)
DE (1)	DE60014212T2 (da)
DK (1)	DK1031575T3 (da)
DZ (1)	DZ3018A1 (da)
EA (1)	EA003218B1 (da)
EE (1)	EE200000193A (da)
ES (1)	ES2226712T3 (da)
GT (1)	GT200000018A (da)
HK (1)	HK1030219A1 (da)
HN (1)	HN2000000021A (da)
HR (1)	HRP20000103A2 (da)
HU (1)	HUP0000907A3 (da)
ID (1)	ID24861A (da)
IL (2)	IL157103A (da)
IN (1)	IN192352B (da)
IS (1)	IS5380A (da)
MA (1)	MA25072A1 (da)
NO (1)	NO20000965L (da)
NZ (1)	NZ503062A (da)
OA (1)	OA11325A (da)
PA (1)	PA8491201A1 (da)
PE (1)	PE20001550A1 (da)
PL (1)	PL338628A1 (da)
PT (1)	PT1031575E (da)
SG (1)	SG90096A1 (da)
SI (1)	SI1031575T1 (da)
SK (1)	SK284982B6 (da)
TN (1)	TNSN00035A1 (da)
TR (1)	TR200000536A2 (da)
TW (2)	TWI286142B (da)
UA (1)	UA70306C2 (da)
ZA (1)	ZA200000888B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1132388A3 (en) *	2000-03-09	2004-03-03	Pfizer Products Inc.	Hexahydropyrazolo[4,3-c]pyridine metabolites
WO2001091752A1 (en)	2000-05-30	2001-12-06	Merck & Co., Inc.	Melanocortin receptor agonists
AU2003237595A1 (en) *	2003-05-26	2004-12-13	Biocon Limited	Process for the preparation of s(+)-2-ethoxy-4-(n-{1-(2-piperidinophelyl)-3-methyl-1- butyl} aminocarbonylmethyl)benzoic acid derivatives
WO2005027913A1 (en) *	2003-09-19	2005-03-31	Pfizer Products Inc.	Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and a growth hormone secretagogue
US9117477B2 (en)	2013-05-08	2015-08-25	HGST Netherlands B.V.	Perpendicular magnetic recording media having novel seed layer
WO2014192294A1 (en) *	2013-05-28	2014-12-04	Raqualia Pharma Inc.	Polymorph forms
CN109320515A (zh) *	2018-11-22	2019-02-12	常州大学	一种Capromorelin手性中间体的不对称合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8610980D0 (en)	1986-05-06	1986-06-11	Ici America Inc	Heterocyclic fused tricyclic compounds
GB8901423D0 (en)	1989-01-23	1989-03-15	Fujisawa Pharmaceutical Co	Pyrazolopyridine compound and processes for preparation thereof
US5536716A (en)	1992-12-11	1996-07-16	Merck & Co., Inc.	Spiro piperidines and homologs which promote release of growth hormone
PL322706A1 (en)	1993-11-09	1998-02-16	Merck & Co Inc	Piperidines, pyrolidines and hexahydro-1h-azepins enhancing growth hormone liberation
US5609150A (en)	1995-04-18	1997-03-11	Maged; Jeffrey M.	Method for dilating respiratory passages
TW432073B (en)	1995-12-28	2001-05-01	Pfizer	Pyrazolopyridine compounds
WO1997034604A1 (en)	1996-03-21	1997-09-25	Merck & Co., Inc.	4-spiroindoline piperidines promote release of growth hormone
WO1997036873A1 (en)	1996-04-03	1997-10-09	Merck & Co., Inc.	Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone
UA64751C2 (uk) *	1997-06-25	2004-03-15	Пфайзер Продактс Інк.	Спосіб лікування інсулінової толерантності речовинами, які посилюють секрецію гормону росту (варіанти) та фармацевтична композиція (варіанти)
JP3514774B2 (ja)	1997-06-25	2004-03-31	ファイザー・インク	成長ホルモン分泌促進薬としてのジペプチド誘導体
UA53716C2 (uk)	1997-06-25	2003-02-17	Пфайзер Продактс Інк.	Тартратна сіль заміщеного дипептиду, спосіб її одержання, проміжні сполуки та спосіб їх одержання, фармацевтична композиція (варіанти), спосіб підвищення рівнів ендогенного гормону росту та спосіб лікування або профілактики захворювань (варіанти)

2000
- 2000-02-01 US US09/496,075 patent/US6541634B2/en not_active Expired - Lifetime
- 2000-02-16 SG SG200000835A patent/SG90096A1/en unknown
- 2000-02-17 IL IL157103A patent/IL157103A/en not_active IP Right Cessation
- 2000-02-17 IL IL134599A patent/IL134599A/en not_active IP Right Cessation
- 2000-02-18 IS IS5380A patent/IS5380A/is unknown
- 2000-02-21 HN HN2000000021A patent/HN2000000021A/es unknown
- 2000-02-21 IN IN138DE2000 patent/IN192352B/en unknown
- 2000-02-21 SK SK230-2000A patent/SK284982B6/sk not_active IP Right Cessation
- 2000-02-22 TW TW089103014A patent/TWI286142B/zh not_active IP Right Cessation
- 2000-02-22 BG BG104175A patent/BG104175A/bg unknown
- 2000-02-22 TW TW095134050A patent/TW200718702A/zh unknown
- 2000-02-23 MA MA25911A patent/MA25072A1/fr unknown
- 2000-02-23 OA OA1200000050A patent/OA11325A/en unknown
- 2000-02-23 GT GT200000018A patent/GT200000018A/es unknown
- 2000-02-23 ZA ZA200000888A patent/ZA200000888B/xx unknown
- 2000-02-23 TN TNTNSN00035A patent/TNSN00035A1/fr unknown
- 2000-02-23 DZ DZ000037A patent/DZ3018A1/xx active
- 2000-02-23 PE PE2000000148A patent/PE20001550A1/es not_active Application Discontinuation
- 2000-02-23 CO CO00012732A patent/CO5160252A1/es unknown
- 2000-02-24 UA UA2000021098A patent/UA70306C2/uk unknown
- 2000-02-24 ID IDP20000134D patent/ID24861A/id unknown
- 2000-02-24 JP JP2000047626A patent/JP3437813B2/ja not_active Expired - Lifetime
- 2000-02-24 AP APAP/P/2000/001754A patent/AP1221A/en active
- 2000-02-24 AU AU19471/00A patent/AU764122B2/en not_active Ceased
- 2000-02-24 AR ARP000100784A patent/AR029617A1/es active IP Right Grant
- 2000-02-24 CA CA2299495A patent/CA2299495C/en not_active Expired - Lifetime
- 2000-02-24 PA PA20008491201A patent/PA8491201A1/es unknown
- 2000-02-25 EA EA200000172A patent/EA003218B1/ru not_active IP Right Cessation
- 2000-02-25 NO NO20000965A patent/NO20000965L/no not_active Application Discontinuation
- 2000-02-25 PT PT00301526T patent/PT1031575E/pt unknown
- 2000-02-25 EP EP04009914A patent/EP1449842A1/en not_active Withdrawn
- 2000-02-25 KR KR10-2000-0009296A patent/KR100372063B1/ko active IP Right Grant
- 2000-02-25 SI SI200030502T patent/SI1031575T1/xx unknown
- 2000-02-25 EP EP00301526A patent/EP1031575B1/en not_active Expired - Lifetime
- 2000-02-25 CN CNA200610073385XA patent/CN1837205A/zh active Pending
- 2000-02-25 DE DE60014212T patent/DE60014212T2/de not_active Expired - Lifetime
- 2000-02-25 AT AT00301526T patent/ATE277944T1/de not_active IP Right Cessation
- 2000-02-25 HR HR20000103A patent/HRP20000103A2/hr not_active Application Discontinuation
- 2000-02-25 PL PL00338628A patent/PL338628A1/xx not_active IP Right Cessation
- 2000-02-25 TR TR2000/00536A patent/TR200000536A2/xx unknown
- 2000-02-25 CN CNB001053884A patent/CN1137891C/zh not_active Expired - Lifetime
- 2000-02-25 ES ES00301526T patent/ES2226712T3/es not_active Expired - Lifetime
- 2000-02-25 CN CNA031075525A patent/CN1515570A/zh active Pending
- 2000-02-25 DK DK00301526T patent/DK1031575T3/da active
- 2000-02-25 NZ NZ503062A patent/NZ503062A/en unknown
- 2000-02-25 HU HU0000907A patent/HUP0000907A3/hu unknown
- 2000-02-28 EE EEP200000193A patent/EE200000193A/xx unknown
- 2000-02-28 BR BRPI0017522A patent/BRPI0017522B8/pt not_active IP Right Cessation
- 2000-02-28 BR BRPI0000967A patent/BRPI0000967B8/pt not_active IP Right Cessation
2001
- 2001-02-21 HK HK01101247A patent/HK1030219A1/xx not_active IP Right Cessation
2002
- 2002-07-20 KR KR1020020042729A patent/KR100361783B1/ko active IP Right Grant
- 2002-10-30 US US10/283,720 patent/US6673929B2/en not_active Expired - Lifetime
2003
- 2003-04-04 JP JP2003101700A patent/JP2003261565A/ja active Pending
- 2003-04-04 JP JP2003101688A patent/JP4051314B2/ja not_active Expired - Lifetime
2006
- 2006-05-05 AR ARP060101825A patent/AR053722A2/es active IP Right Grant

Also Published As

Publication number	Publication date
NO20000965L (no)	2000-08-28
KR100372063B1 (ko)	2003-02-14
SK284982B6 (sk)	2006-03-02
EA200000172A2 (ru)	2000-08-28
EA200000172A3 (ru)	2000-10-30
IN192352B (da)	2004-04-10
BRPI0000967B8 (pt)	2021-12-07
HK1030219A1 (en)	2001-04-27
AP2000001754A0 (en)	2000-03-31
MA25072A1 (fr)	2000-10-01
BRPI0017522B1 (pt)	2013-09-24
JP4051314B2 (ja)	2008-02-20
BRPI0000967A (pt)	2001-09-11
EP1031575A1 (en)	2000-08-30
SG90096A1 (en)	2002-07-23
DE60014212D1 (de)	2004-11-04
US20030158414A1 (en)	2003-08-21
EE200000193A (et)	2000-10-16
EP1031575B1 (en)	2004-09-29
US6673929B2 (en)	2004-01-06
TWI286142B (en)	2007-09-01
BRPI0017522B8 (pt)	2021-05-25
ATE277944T1 (de)	2004-10-15
HU0000907D0 (en)	2000-04-28
PA8491201A1 (es)	2001-04-30
SK2302000A3 (en)	2000-11-07
BRPI0000967B1 (pt)	2012-06-12
TR200000536A2 (tr)	2000-09-21
JP2003327585A (ja)	2003-11-19
JP2000247974A (ja)	2000-09-12
US20020002283A1 (en)	2002-01-03
JP3437813B2 (ja)	2003-08-18
GT200000018A (es)	2001-08-16
TW200718702A (en)	2007-05-16
CA2299495C (en)	2010-06-15
HRP20000103A2 (en)	2001-04-30
JP2003261565A (ja)	2003-09-19
PE20001550A1 (es)	2001-01-11
IL157103A0 (en)	2004-02-08
KR20020065455A (ko)	2002-08-13
KR100361783B1 (ko)	2002-11-22
IL134599A0 (en)	2001-04-30
ZA200000888B (en)	2001-08-23
AR053722A2 (es)	2007-05-16
BRPI0017522A2 (da)	2009-12-22
SI1031575T1 (en)	2005-02-28
CN1515570A (zh)	2004-07-28
CO5160252A1 (es)	2002-05-30
BG104175A (bg)	2000-12-29
ES2226712T3 (es)	2005-04-01
CA2299495A1 (en)	2000-08-26
NO20000965D0 (no)	2000-02-25
OA11325A (en)	2003-10-27
EP1449842A1 (en)	2004-08-25
AU1947100A (en)	2000-08-31
IL157103A (en)	2007-07-24
CN1837205A (zh)	2006-09-27
AR029617A1 (es)	2003-07-10
CN1137891C (zh)	2004-02-11
IL134599A (en)	2006-12-10
KR20010006698A (ko)	2001-01-26
EA003218B1 (ru)	2003-02-27
TNSN00035A1 (fr)	2005-11-10
IS5380A (is)	2000-08-27
PL338628A1 (en)	2000-08-28
US6541634B2 (en)	2003-04-01
PT1031575E (pt)	2004-11-30
HUP0000907A3 (en)	2001-05-28
HUP0000907A2 (en)	2001-03-28
NZ503062A (en)	2001-07-27
ID24861A (id)	2000-08-31
DZ3018A1 (fr)	2004-03-20
AP1221A (en)	2003-11-03
CN1270960A (zh)	2000-10-25
AU764122B2 (en)	2003-08-07
HN2000000021A (es)	2001-02-02
UA70306C2 (en)	2004-10-15
DE60014212T2 (de)	2005-12-15

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DE69837264D1 (de)	2007-04-19	Dipeptidderivate zur förderung der sekretion von wachstumshormon
IS5276A (is)	1999-11-26	Tartrat salt af setnu dípeptíði sem vaxtarhormónsseytir
ATE362472T1 (de)	2007-06-15	Wachstumhormonsekretionsförderer
DK1044969T3 (da)	2007-04-23	Fremgangsmåde og mellemprodukter til fremstilling af anti-cancer forbindelser
DK1150966T3 (da)	2002-12-30	Fremgangsmåde til fremstilling af 5-cyanophthalid
EE200200183A (et)	2003-06-16	Meetod polüisobuteenfenooli sisaldavate Mannichi aduktide saamiseks
FI20000564A (fi)	2001-04-16	Menetelmä nanolaminaattien valmistamiseksi
DK1140886T3 (da)	2003-07-28	Fremgangsmåde til fremstilling af 5-cyanophtalid
DK1147075T3 (da)	2003-12-08	Fremgangsmåde til fremstilling af L-phenylephrinhydrochlorid
DE60038118D1 (de)	2008-04-03	Formulierungen von wachstumshormonen
DK1114023T3 (da)	2004-09-27	Fremgangsmåde til fremstilling af carboxylsyrer
ATE375996T1 (de)	2007-11-15	Sekretionsfordermittel fur wachtumshormon
DK1131083T3 (da)	2004-04-26	Anvendelse af væksthormonfrigørende forbindelser og antagonister deraf til behandling af tumorer
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ATE339438T1 (de)	2006-10-15	Substanziell kristalline form von melagatran
PT1228056E (pt)	2005-02-28	Metodo de preparacao de citaloprame
DK1159296T3 (da)	2004-09-27	Fremgangsmåde til fremstilling af cyclo-(Asp-DPhe-NMeVal-Arg-Gly)
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DK1399577T3 (da)	2007-06-04	Fremgangsmåde til fremstilling af L-aminosyrer
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