DK1019039T3 - Komprimeret nitroglycerintablet og fremgangsmåde til dens fremstilling - Google Patents

Komprimeret nitroglycerintablet og fremgangsmåde til dens fremstilling

Info

Publication number
DK1019039T3
DK1019039T3 DK98948293T DK98948293T DK1019039T3 DK 1019039 T3 DK1019039 T3 DK 1019039T3 DK 98948293 T DK98948293 T DK 98948293T DK 98948293 T DK98948293 T DK 98948293T DK 1019039 T3 DK1019039 T3 DK 1019039T3
Authority
DK
Denmark
Prior art keywords
nitroglycerin
tablets
stable
direct compression
compression technology
Prior art date
Application number
DK98948293T
Other languages
English (en)
Inventor
Roberto L Capella
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of DK1019039T3 publication Critical patent/DK1019039T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK98948293T 1997-10-03 1998-09-16 Komprimeret nitroglycerintablet og fremgangsmåde til dens fremstilling DK1019039T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6110597P 1997-10-03 1997-10-03
PCT/US1998/019356 WO1999017766A1 (en) 1997-10-03 1998-09-16 Compressed nitroglycerin tablet and its method of manufacture

Publications (1)

Publication Number Publication Date
DK1019039T3 true DK1019039T3 (da) 2002-03-25

Family

ID=22033623

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98948293T DK1019039T3 (da) 1997-10-03 1998-09-16 Komprimeret nitroglycerintablet og fremgangsmåde til dens fremstilling

Country Status (16)

Country Link
US (1) US6500456B1 (da)
EP (1) EP1019039B1 (da)
JP (1) JP2001518500A (da)
KR (1) KR100569763B1 (da)
AT (1) ATE209911T1 (da)
AU (1) AU759018B2 (da)
BR (1) BR9812605B1 (da)
CA (1) CA2299231C (da)
DE (1) DE69802832T2 (da)
DK (1) DK1019039T3 (da)
ES (1) ES2169558T3 (da)
IL (1) IL134395A (da)
NZ (1) NZ502878A (da)
PT (1) PT1019039E (da)
TW (1) TWI228989B (da)
WO (1) WO1999017766A1 (da)

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CA2348452A1 (en) * 1998-10-27 2000-05-04 Biovail Technologies Ltd. Microparticles containing peg and/or peg glyceryl esters
US7815937B2 (en) * 1998-10-27 2010-10-19 Biovail Laboratories International Srl Quick dissolve compositions and tablets based thereon
US7815936B2 (en) 2001-10-30 2010-10-19 Evonik Degussa Gmbh Use of granular materials based on pyrogenically produced silicon dioxide in pharmaceutical compositions
US20040109889A1 (en) 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
KR101170844B1 (ko) * 2003-02-24 2012-08-02 파마슈티칼 프로덕션스, 인크. 경점막 약물 전달 시스템
US9358296B2 (en) 2003-02-24 2016-06-07 Pharmaceutical Productions Inc. Transmucosal drug delivery system
US10172810B2 (en) 2003-02-24 2019-01-08 Pharmaceutical Productions, Inc. Transmucosal ketamine delivery composition
US9498454B2 (en) 2003-02-24 2016-11-22 Pharmaceutical Productions Inc. Transmucosal drug delivery system
US9254294B2 (en) 2003-02-24 2016-02-09 Pharmaceutical Productions Inc. Transmucosal hormone delivery system
CA2530843A1 (en) * 2003-07-01 2005-01-20 Todd Maibach Film comprising therapeutic agents
US7999003B2 (en) * 2003-08-26 2011-08-16 Mannatech, Incorporated Antioxidant compositions and methods thereto
US20060134202A1 (en) * 2004-12-22 2006-06-22 Hack Jacob C Homeopathic sublingual dosage forms and methods thereof
US8865743B2 (en) 2006-01-06 2014-10-21 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US9289583B2 (en) 2006-01-06 2016-03-22 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US8202535B2 (en) 2006-01-06 2012-06-19 Acelrx Pharmaceuticals, Inc. Small-volume oral transmucosal dosage forms
US9066847B2 (en) 2007-01-05 2015-06-30 Aceirx Pharmaceuticals, Inc. Storage and dispensing devices for administration of oral transmucosal dosage forms
US8753308B2 (en) 2006-01-06 2014-06-17 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US8252328B2 (en) * 2006-01-06 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US8252329B2 (en) 2007-01-05 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US8535714B2 (en) 2006-01-06 2013-09-17 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8357114B2 (en) 2006-01-06 2013-01-22 Acelrx Pharmaceuticals, Inc. Drug dispensing device with flexible push rod
US20100215774A1 (en) * 2007-02-09 2010-08-26 Todd Maibach Film comprising nitroglycerin
US20090004254A1 (en) * 2007-06-19 2009-01-01 Todd Maibach Film comprising active drugs
US20090048237A1 (en) * 2007-08-07 2009-02-19 Acelrx Pharmaceuticals, Inc. Compositions and methods for procedural sedation and analgesia using oral transmucosal dosage forms
US8945592B2 (en) * 2008-11-21 2015-02-03 Acelrx Pharmaceuticals, Inc. Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same
US20110091544A1 (en) * 2009-10-16 2011-04-21 Acelrx Pharmaceuticals, Inc. Compositions and Methods for Mild Sedation, Anxiolysis and Analgesia in the Procedural Setting
EP2990032A1 (en) 2010-08-03 2016-03-02 G. Pohl-Boskamp GmbH & Co. KG Use of glyceryl trinitrate for treating traumatic edema
PL2678000T3 (pl) 2011-02-25 2018-08-31 G. Pohl-Boskamp Gmbh & Co. Kg Stabilizowane granulaty zawierające triazotan glicerolu
EP2668947B1 (en) 2012-05-31 2016-11-30 G. Pohl-Boskamp GmbH & Co. KG Induction of arteriogenesis with a nitric oxide-donor such as nitroglycerin
US9248099B2 (en) 2012-05-31 2016-02-02 Desmoid Aktiengesellschaft Use of stabilized granules containing glyceryl trinitrate for arteriogenesis
EP2668948A1 (en) * 2012-05-31 2013-12-04 G. Pohl-Boskamp GmbH & Co. KG Use of stabilized granules containing glyceryl trinitrate for arteriogenesis
US20150306090A1 (en) * 2012-08-31 2015-10-29 Astellas Pharma Inc. Orally administered medical composition
HUE051406T2 (hu) 2012-11-14 2021-03-01 Grace W R & Co Biológiailag aktív anyagot és rendezetlen szervetlen oxidot tartalmazó kompozíciók
US20140303227A1 (en) * 2013-03-14 2014-10-09 Pharmaceutical Productions Inc. Transmucosal hormone delivery system
EP2878310B1 (en) 2013-11-29 2017-01-11 G. Pohl-Boskamp GmbH & Co. KG Sprayable aqueous composition comprising glyceryl trinitrate
MX2015006022A (es) * 2014-02-07 2015-10-14 Scilabs Pharmaceuticals Sistemas de administracion de farmacos sublinguales, totalmente naturales, no toxicos.
CN113679682A (zh) * 2020-05-19 2021-11-23 珠海润都制药股份有限公司 一种***舌下片及其制备方法
CN114469881A (zh) * 2022-03-14 2022-05-13 河北坤安药业有限公司 一种***片及其制备方法
CN115154431B (zh) * 2022-07-21 2024-03-12 南京卓康医药科技有限公司 一种***片剂及其制备方法

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DE2357503A1 (de) * 1973-11-17 1975-05-28 Cassella Farbwerke Mainkur Ag Verfahren zur herstellung von festen carbocromen-hydrochlorid enthaltenden praeparaten
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
WO1996036330A2 (en) * 1995-05-17 1996-11-21 Cedars-Sinai Medical Center Compositions containing fatty acids for improving digestion and absorption in the small intestine
US5874418A (en) * 1997-05-05 1999-02-23 Cydex, Inc. Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use

Also Published As

Publication number Publication date
NZ502878A (en) 2002-03-01
AU759018B2 (en) 2003-04-03
ATE209911T1 (de) 2001-12-15
AU9489398A (en) 1999-04-27
IL134395A0 (en) 2001-04-30
EP1019039A1 (en) 2000-07-19
DE69802832D1 (de) 2002-01-17
WO1999017766A1 (en) 1999-04-15
DE69802832T2 (de) 2002-06-20
ES2169558T3 (es) 2002-07-01
KR20010030839A (ko) 2001-04-16
CA2299231C (en) 2003-03-18
TWI228989B (en) 2005-03-11
BR9812605B1 (pt) 2009-01-13
JP2001518500A (ja) 2001-10-16
BR9812605A (pt) 2000-08-01
CA2299231A1 (en) 1999-04-15
PT1019039E (pt) 2002-04-29
US6500456B1 (en) 2002-12-31
KR100569763B1 (ko) 2006-04-11
EP1019039B1 (en) 2001-12-05
IL134395A (en) 2005-08-31

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