DK0975594T3 - Fremgangsmåde til fremstilling af indolderivater - Google Patents

Fremgangsmåde til fremstilling af indolderivater

Info

Publication number
DK0975594T3
DK0975594T3 DK98933651T DK98933651T DK0975594T3 DK 0975594 T3 DK0975594 T3 DK 0975594T3 DK 98933651 T DK98933651 T DK 98933651T DK 98933651 T DK98933651 T DK 98933651T DK 0975594 T3 DK0975594 T3 DK 0975594T3
Authority
DK
Denmark
Prior art keywords
preparation
indole derivatives
indole
derivatives
Prior art date
Application number
DK98933651T
Other languages
Danish (da)
English (en)
Inventor
David Charles Waite
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0975594T3 publication Critical patent/DK0975594T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C311/04—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
DK98933651T 1997-07-08 1998-06-16 Fremgangsmåde til fremstilling af indolderivater DK0975594T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9714383.8A GB9714383D0 (en) 1997-07-08 1997-07-08 Improved process
PCT/EP1998/003996 WO1999002493A1 (fr) 1997-07-08 1998-06-16 Procede de production de derives indole

Publications (1)

Publication Number Publication Date
DK0975594T3 true DK0975594T3 (da) 2002-10-14

Family

ID=10815557

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98933651T DK0975594T3 (da) 1997-07-08 1998-06-16 Fremgangsmåde til fremstilling af indolderivater

Country Status (15)

Country Link
US (1) US6281357B1 (fr)
EP (1) EP0975594B1 (fr)
AR (1) AR013183A1 (fr)
AT (1) ATE224367T1 (fr)
AU (1) AU8339798A (fr)
CA (1) CA2286720A1 (fr)
DE (1) DE69808068T2 (fr)
DK (1) DK0975594T3 (fr)
ES (1) ES2182342T3 (fr)
GB (1) GB9714383D0 (fr)
IL (1) IL132442A0 (fr)
PL (1) PL337000A1 (fr)
PT (1) PT975594E (fr)
WO (1) WO1999002493A1 (fr)
ZA (1) ZA985918B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9801690D0 (en) * 1998-01-27 1998-03-25 Pfizer Ltd Therapeutic agents
US6100291A (en) * 1998-03-16 2000-08-08 Allelix Biopharmaceuticals Inc. Pyrrolidine-indole compounds having 5-HT6 affinity
JP4897221B2 (ja) * 2002-12-20 2012-03-14 チバ ホールディング インコーポレーテッド アミン類の合成及びその合成のための中間体
US20100022581A1 (en) * 2008-07-02 2010-01-28 Memory Pharmaceuticals Corporation Pyrrolidine-substituted azaindole compounds having 5-ht6 receptor affinity
CN102775342A (zh) * 2011-05-12 2012-11-14 上海医药工业研究院 一种抗偏头痛药物阿莫曲坦的制备方法
CN109311897B (zh) 2017-03-20 2021-07-20 福马治疗股份有限公司 作为丙酮酸激酶(pkr)活化剂的吡咯并吡咯组合物
US20200129485A1 (en) 2018-09-19 2020-04-30 Forma Therapeutics, Inc. Treating sickle cell disease with a pyruvate kinase r activating compound
US20230055923A1 (en) 2018-09-19 2023-02-23 Forma Therapeutics, Inc. Activating pyruvate kinase r
CN110483341A (zh) * 2019-07-23 2019-11-22 上海药明康德新药开发有限公司 一种1-氰基-n-甲基甲磺酰胺的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
AU651637B2 (en) * 1990-10-15 1994-07-28 Pfizer Inc. Indole derivatives
GB9103770D0 (en) * 1991-02-22 1991-04-10 Glaxo Group Ltd Chemical compounds
CA2084531A1 (fr) * 1991-12-19 1993-06-20 David W. Smith Derives antimigraines 4-pyrimidinyle et pyridinyle d'indol-3yl-alkylpiperazines

Also Published As

Publication number Publication date
CA2286720A1 (fr) 1999-01-21
ZA985918B (en) 2000-01-10
EP0975594B1 (fr) 2002-09-18
PL337000A1 (en) 2000-07-31
DE69808068D1 (de) 2002-10-24
GB9714383D0 (en) 1997-09-10
ATE224367T1 (de) 2002-10-15
PT975594E (pt) 2002-12-31
EP0975594A1 (fr) 2000-02-02
US6281357B1 (en) 2001-08-28
AU8339798A (en) 1999-02-08
AR013183A1 (es) 2000-12-13
ES2182342T3 (es) 2003-03-01
IL132442A0 (en) 2001-03-19
WO1999002493A1 (fr) 1999-01-21
DE69808068T2 (de) 2003-02-06

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