DE69808068D1 - Verfahren zur herstellung von indolderivaten - Google Patents
Verfahren zur herstellung von indolderivatenInfo
- Publication number
- DE69808068D1 DE69808068D1 DE69808068T DE69808068T DE69808068D1 DE 69808068 D1 DE69808068 D1 DE 69808068D1 DE 69808068 T DE69808068 T DE 69808068T DE 69808068 T DE69808068 T DE 69808068T DE 69808068 D1 DE69808068 D1 DE 69808068D1
- Authority
- DE
- Germany
- Prior art keywords
- producing
- indolder derivatives
- indolder
- derivatives
- producing indolder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C311/04—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9714383.8A GB9714383D0 (en) | 1997-07-08 | 1997-07-08 | Improved process |
| PCT/EP1998/003996 WO1999002493A1 (en) | 1997-07-08 | 1998-06-16 | Process for the production of indole derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69808068D1 true DE69808068D1 (de) | 2002-10-24 |
| DE69808068T2 DE69808068T2 (de) | 2003-02-06 |
Family
ID=10815557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69808068T Expired - Fee Related DE69808068T2 (de) | 1997-07-08 | 1998-06-16 | Verfahren zur herstellung von indolderivaten |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6281357B1 (de) |
| EP (1) | EP0975594B1 (de) |
| AR (1) | AR013183A1 (de) |
| AT (1) | ATE224367T1 (de) |
| AU (1) | AU8339798A (de) |
| CA (1) | CA2286720A1 (de) |
| DE (1) | DE69808068T2 (de) |
| DK (1) | DK0975594T3 (de) |
| ES (1) | ES2182342T3 (de) |
| GB (1) | GB9714383D0 (de) |
| IL (1) | IL132442A0 (de) |
| PL (1) | PL337000A1 (de) |
| PT (1) | PT975594E (de) |
| WO (1) | WO1999002493A1 (de) |
| ZA (1) | ZA985918B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9801690D0 (en) * | 1998-01-27 | 1998-03-25 | Pfizer Ltd | Therapeutic agents |
| US6100291A (en) * | 1998-03-16 | 2000-08-08 | Allelix Biopharmaceuticals Inc. | Pyrrolidine-indole compounds having 5-HT6 affinity |
| CA2508290C (en) | 2002-12-20 | 2017-02-28 | Ciba Specialty Chemicals Holding Inc. | Synthesis of amines and intermediates for the synthesis thereof |
| US20100022581A1 (en) * | 2008-07-02 | 2010-01-28 | Memory Pharmaceuticals Corporation | Pyrrolidine-substituted azaindole compounds having 5-ht6 receptor affinity |
| CN102775342A (zh) * | 2011-05-12 | 2012-11-14 | 上海医药工业研究院 | 一种抗偏头痛药物阿莫曲坦的制备方法 |
| PL3448859T3 (pl) | 2017-03-20 | 2020-02-28 | Forma Therapeutics, Inc. | Kompozycje pirolopirolu jako aktywatory kinazy pirogronianowej (PKR) |
| JP7450610B2 (ja) | 2018-09-19 | 2024-03-15 | ノヴォ・ノルディスク・ヘルス・ケア・アーゲー | ピルビン酸キナーゼｒの活性化 |
| US20200129485A1 (en) | 2018-09-19 | 2020-04-30 | Forma Therapeutics, Inc. | Treating sickle cell disease with a pyruvate kinase r activating compound |
| CN110483341A (zh) * | 2019-07-23 | 2019-11-22 | 上海药明康德新药开发有限公司 | 一种1-氰基-n-甲基甲磺酰胺的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8419575D0 (en) * | 1984-08-01 | 1984-09-05 | Glaxo Group Ltd | Chemical compounds |
| WO1992006973A1 (en) * | 1990-10-15 | 1992-04-30 | Pfizer Inc. | Indole derivatives |
| GB9103770D0 (en) * | 1991-02-22 | 1991-04-10 | Glaxo Group Ltd | Chemical compounds |
| CA2084531A1 (en) * | 1991-12-19 | 1993-06-20 | David W. Smith | Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines |
-
1997
- 1997-07-08 GB GBGB9714383.8A patent/GB9714383D0/en active Pending
-
1998
- 1998-06-16 CA CA002286720A patent/CA2286720A1/en not_active Abandoned
- 1998-06-16 IL IL13244298A patent/IL132442A0/xx unknown
- 1998-06-16 ES ES98933651T patent/ES2182342T3/es not_active Expired - Lifetime
- 1998-06-16 AT AT98933651T patent/ATE224367T1/de not_active IP Right Cessation
- 1998-06-16 PT PT98933651T patent/PT975594E/pt unknown
- 1998-06-16 WO PCT/EP1998/003996 patent/WO1999002493A1/en not_active Application Discontinuation
- 1998-06-16 US US09/381,072 patent/US6281357B1/en not_active Expired - Fee Related
- 1998-06-16 AU AU83397/98A patent/AU8339798A/en not_active Abandoned
- 1998-06-16 EP EP98933651A patent/EP0975594B1/de not_active Expired - Lifetime
- 1998-06-16 DE DE69808068T patent/DE69808068T2/de not_active Expired - Fee Related
- 1998-06-16 PL PL98337000A patent/PL337000A1/xx unknown
- 1998-06-16 DK DK98933651T patent/DK0975594T3/da active
- 1998-07-06 AR ARP980103279A patent/AR013183A1/es not_active Application Discontinuation
- 1998-07-06 ZA ZA9805918A patent/ZA985918B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB9714383D0 (en) | 1997-09-10 |
| ES2182342T3 (es) | 2003-03-01 |
| EP0975594B1 (de) | 2002-09-18 |
| CA2286720A1 (en) | 1999-01-21 |
| ATE224367T1 (de) | 2002-10-15 |
| EP0975594A1 (de) | 2000-02-02 |
| ZA985918B (en) | 2000-01-10 |
| DK0975594T3 (da) | 2002-10-14 |
| WO1999002493A1 (en) | 1999-01-21 |
| AR013183A1 (es) | 2000-12-13 |
| PT975594E (pt) | 2002-12-31 |
| US6281357B1 (en) | 2001-08-28 |
| DE69808068T2 (de) | 2003-02-06 |
| AU8339798A (en) | 1999-02-08 |
| IL132442A0 (en) | 2001-03-19 |
| PL337000A1 (en) | 2000-07-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |