DK0869774T3 - Fremgangsmåde til fremstilling af vedvarende frigivende partikler - Google Patents

Fremgangsmåde til fremstilling af vedvarende frigivende partikler

Info

Publication number
DK0869774T3
DK0869774T3 DK96935641T DK96935641T DK0869774T3 DK 0869774 T3 DK0869774 T3 DK 0869774T3 DK 96935641 T DK96935641 T DK 96935641T DK 96935641 T DK96935641 T DK 96935641T DK 0869774 T3 DK0869774 T3 DK 0869774T3
Authority
DK
Denmark
Prior art keywords
core particles
organic solvent
active substance
release particles
producing sustained
Prior art date
Application number
DK96935641T
Other languages
English (en)
Inventor
Nils-Ove Gustafsson
Timo Laakso
Peter Fyhr
Monica Joensson
Original Assignee
Jagotec Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jagotec Ag filed Critical Jagotec Ag
Application granted granted Critical
Publication of DK0869774T3 publication Critical patent/DK0869774T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK96935641T 1995-10-19 1996-09-03 Fremgangsmåde til fremstilling af vedvarende frigivende partikler DK0869774T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9503672A SE505146C2 (sv) 1995-10-19 1995-10-19 Partiklar för fördröjd frisättning
PCT/SE1996/001091 WO1997014408A1 (en) 1995-10-19 1996-09-03 Sustained release particles

Publications (1)

Publication Number Publication Date
DK0869774T3 true DK0869774T3 (da) 2003-03-24

Family

ID=20399887

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96935641T DK0869774T3 (da) 1995-10-19 1996-09-03 Fremgangsmåde til fremstilling af vedvarende frigivende partikler

Country Status (17)

Country Link
US (1) US6120787A (da)
EP (3) EP1142569B1 (da)
JP (1) JP2000501380A (da)
KR (1) KR100482262B1 (da)
AT (2) ATE326953T1 (da)
AU (1) AU699080B2 (da)
CZ (1) CZ293059B6 (da)
DE (3) DE69625240T2 (da)
DK (1) DK0869774T3 (da)
ES (2) ES2125209T3 (da)
HK (1) HK1011182A1 (da)
HU (1) HUP9901205A3 (da)
IL (1) IL124052A (da)
NO (1) NO320392B1 (da)
PT (1) PT869774E (da)
SE (1) SE505146C2 (da)
WO (1) WO1997014408A1 (da)

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Also Published As

Publication number Publication date
AU699080B2 (en) 1998-11-19
ATE228826T1 (de) 2002-12-15
SE9503672D0 (sv) 1995-10-19
NO320392B1 (no) 2005-11-28
EP1142569A2 (en) 2001-10-10
HUP9901205A2 (hu) 1999-08-30
DE69636177D1 (de) 2006-06-29
JP2000501380A (ja) 2000-02-08
ES2267637T3 (es) 2007-03-16
NO981558D0 (no) 1998-04-06
NO981558L (no) 1998-04-06
DE69636177T2 (de) 2007-03-29
WO1997014408A1 (en) 1997-04-24
HK1011182A1 (en) 1999-07-09
CZ117398A3 (cs) 1998-09-16
PT869774E (pt) 2003-04-30
ATE326953T1 (de) 2006-06-15
ES2125209T1 (es) 1999-03-01
EP0869774B1 (en) 2002-12-04
DE869774T1 (de) 1999-06-02
DE69625240T2 (de) 2003-09-11
KR100482262B1 (ko) 2006-04-14
CZ293059B6 (cs) 2004-01-14
AU7347896A (en) 1997-05-07
IL124052A (en) 2000-11-21
EP1142569B1 (en) 2006-05-24
HUP9901205A3 (en) 2001-04-28
EP1716849A1 (en) 2006-11-02
ES2125209T3 (es) 2003-07-01
US6120787A (en) 2000-09-19
SE9503672L (sv) 1997-04-20
SE505146C2 (sv) 1997-06-30
KR19990064267A (ko) 1999-07-26
EP1142569A3 (en) 2003-05-21
DE69625240D1 (de) 2003-01-16
EP0869774A1 (en) 1998-10-14

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