SE9503672L - Partiklar för fördröjd frisättning - Google Patents
Partiklar för fördröjd frisättningInfo
- Publication number
- SE9503672L SE9503672L SE9503672A SE9503672A SE9503672L SE 9503672 L SE9503672 L SE 9503672L SE 9503672 A SE9503672 A SE 9503672A SE 9503672 A SE9503672 A SE 9503672A SE 9503672 L SE9503672 L SE 9503672L
- Authority
- SE
- Sweden
- Prior art keywords
- core particles
- particles
- organic solvent
- active substance
- delayed release
- Prior art date
Links
- 230000003111 delayed effect Effects 0.000 title 1
- 239000002245 particle Substances 0.000 title 1
- 239000007771 core particle Substances 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 239000011859 microparticle Substances 0.000 abstract 2
- 239000003960 organic solvent Substances 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 229940088623 biologically active substance Drugs 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 230000001627 detrimental effect Effects 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Priority Applications (25)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9503672A SE505146C2 (sv) | 1995-10-19 | 1995-10-19 | Partiklar för fördröjd frisättning |
EP01117830A EP1142569B1 (en) | 1995-10-19 | 1996-09-03 | Coating of small particles |
AT01117830T ATE326953T1 (de) | 1995-10-19 | 1996-09-03 | Umhüllung kleiner partikel |
US09/051,709 US6120787A (en) | 1995-10-19 | 1996-09-03 | Sustained release particles |
JP9515728A JP2000501380A (ja) | 1995-10-19 | 1996-09-03 | 持続放出性粒子 |
ES01117830T ES2267637T3 (es) | 1995-10-19 | 1996-09-03 | Revestimiento de pequeñas particulas. |
PCT/SE1996/001091 WO1997014408A1 (en) | 1995-10-19 | 1996-09-03 | Sustained release particles |
DE69625240T DE69625240T2 (de) | 1995-10-19 | 1996-09-03 | Methode zur herstellung von partikeln mit verzoegerter freisetzung |
EP96935641A EP0869774B1 (en) | 1995-10-19 | 1996-09-03 | Method for manufacturing sustained release particles |
EP06010350A EP1716849A1 (en) | 1995-10-19 | 1996-09-03 | Coating of small particles |
KR1019980702757A KR100482262B1 (ko) | 1995-10-19 | 1996-09-03 | 서방성입자 |
IL12405296A IL124052A (en) | 1995-10-19 | 1996-09-03 | Method of preparing parenterally administrable sustained release microparticles and microparticles obtainable thereby |
HU9901205A HUP9901205A3 (en) | 1995-10-19 | 1996-09-03 | Sustained release particles |
DE69636177T DE69636177T2 (de) | 1995-10-19 | 1996-09-03 | Umhüllung kleiner Partikel |
DE0869774T DE869774T1 (de) | 1995-10-19 | 1996-09-03 | Partikel mit verzögerter freisetzung |
ES96935641T ES2125209T3 (es) | 1995-10-19 | 1996-09-03 | Metodo para fabricar particulas de liberacion sostenida. |
PT96935641T PT869774E (pt) | 1995-10-19 | 1996-09-03 | Metodo para a producao de particulas de libertacao retardada |
CZ19981173A CZ293059B6 (cs) | 1995-10-19 | 1996-09-03 | Způsob přípravy mikročástic s trvalým uvolňováním |
DK96935641T DK0869774T3 (da) | 1995-10-19 | 1996-09-03 | Fremgangsmåde til fremstilling af vedvarende frigivende partikler |
CA 2234615 CA2234615C (en) | 1995-10-19 | 1996-09-03 | Sustained release particles |
AT96935641T ATE228826T1 (de) | 1995-10-19 | 1996-09-03 | Methode zur herstellung von partikeln mit verzoegerter freisetzung |
AU73478/96A AU699080B2 (en) | 1995-10-19 | 1996-09-03 | Sustained release particles |
NO19981558A NO320392B1 (no) | 1995-10-19 | 1998-04-06 | Fremgangsmate for fremstilling av parenteralt administrerbare mikrokapsler med vedvarende frigivelse, og mikropartikler ifolge denne fremgangsmaten |
HK98112027A HK1011182A1 (en) | 1995-10-19 | 1998-11-16 | Method for manufacturing sustained release particles |
HK01108604A HK1038309A1 (en) | 1995-10-19 | 1998-11-16 | Coating of small particles |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9503672A SE505146C2 (sv) | 1995-10-19 | 1995-10-19 | Partiklar för fördröjd frisättning |
Publications (3)
Publication Number | Publication Date |
---|---|
SE9503672D0 SE9503672D0 (sv) | 1995-10-19 |
SE9503672L true SE9503672L (sv) | 1997-04-20 |
SE505146C2 SE505146C2 (sv) | 1997-06-30 |
Family
ID=20399887
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9503672A SE505146C2 (sv) | 1995-10-19 | 1995-10-19 | Partiklar för fördröjd frisättning |
Country Status (17)
Country | Link |
---|---|
US (1) | US6120787A (sv) |
EP (3) | EP1716849A1 (sv) |
JP (1) | JP2000501380A (sv) |
KR (1) | KR100482262B1 (sv) |
AT (2) | ATE228826T1 (sv) |
AU (1) | AU699080B2 (sv) |
CZ (1) | CZ293059B6 (sv) |
DE (3) | DE869774T1 (sv) |
DK (1) | DK0869774T3 (sv) |
ES (2) | ES2267637T3 (sv) |
HK (1) | HK1011182A1 (sv) |
HU (1) | HUP9901205A3 (sv) |
IL (1) | IL124052A (sv) |
NO (1) | NO320392B1 (sv) |
PT (1) | PT869774E (sv) |
SE (1) | SE505146C2 (sv) |
WO (1) | WO1997014408A1 (sv) |
Families Citing this family (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2304096C (en) * | 1997-09-18 | 2003-09-09 | Skyepharma Inc. | Sustained-release liposomal anesthetic compositions |
US20070212422A1 (en) * | 1999-11-10 | 2007-09-13 | Manfred Keller | Dry powder for inhalation |
US6458387B1 (en) * | 1999-10-18 | 2002-10-01 | Epic Therapeutics, Inc. | Sustained release microspheres |
ES2169980B1 (es) | 1999-12-17 | 2003-11-01 | Lipotec Sa | Microcapsulas para la liberacion prolongada de farmacos. |
IT1318380B1 (it) * | 2000-03-09 | 2003-08-25 | Intercos Italiana | Polvere cosmetica rivestita. |
US6495164B1 (en) | 2000-05-25 | 2002-12-17 | Alkermes Controlled Therapeutics, Inc. I | Preparation of injectable suspensions having improved injectability |
DE60039540D1 (de) * | 2000-05-26 | 2008-08-28 | Frohwitter Bernhard | Mittel zum erhalten und/oder korrigieren der blutglukosekonzentration |
US6824822B2 (en) * | 2001-08-31 | 2004-11-30 | Alkermes Controlled Therapeutics Inc. Ii | Residual solvent extraction method and microparticles produced thereby |
SE517422C2 (sv) | 2000-10-06 | 2002-06-04 | Bioglan Ab | Farmaceutiskt acceptabel stärkelse |
SE517421C2 (sv) | 2000-10-06 | 2002-06-04 | Bioglan Ab | Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav |
EP1328258B1 (en) * | 2000-10-06 | 2008-10-01 | Pacira Pharmaceuticals Inc | A controlled-release, parenterally administrable microparticle preparation |
ATE430558T1 (de) | 2000-10-27 | 2009-05-15 | Baxter Healthcare Sa | Herstellung von mikrokügelchen |
SE518007C2 (sv) | 2000-11-16 | 2002-08-13 | Bioglan Ab | Förfarande för framställning av mikropartiklar |
US7034037B2 (en) * | 2001-06-29 | 2006-04-25 | Ethicon, Inc. | Compositions and medical devices utilizing bioabsorbable polymeric waxes and rapamycin |
US7030127B2 (en) * | 2001-06-29 | 2006-04-18 | Ethicon, Inc. | Composition and medical devices utilizing bioabsorbable polymeric waxes |
US6967234B2 (en) * | 2002-12-18 | 2005-11-22 | Ethicon, Inc. | Alkyd-lactone copolymers for medical applications |
ES2307779T3 (es) * | 2001-08-16 | 2008-12-01 | Baxter International Inc. | Formulaciones de microparticulas a base de propelentes. |
US7105181B2 (en) | 2001-10-05 | 2006-09-12 | Jagotec, Ag | Microparticles |
AU2003216288B2 (en) | 2002-02-13 | 2009-09-24 | Duke University | Modulation of immune response by non-peptide binding stress response polypeptides |
SE0201599D0 (sv) | 2002-03-21 | 2002-05-30 | Skyepharma Ab | Microparticles |
US7005136B2 (en) | 2002-03-29 | 2006-02-28 | Ethicon, Inc. | Bone replacement materials utilizing bioabsorbable liquid polymers |
US7326426B2 (en) * | 2002-03-29 | 2008-02-05 | Ethicon, Inc. | Compositions and medical devices utilizing bioabsorbable liquid polymers |
US7368125B2 (en) * | 2002-06-05 | 2008-05-06 | Ethicon, Inc. | Amphiphilic polymers for medical applications |
US7026374B2 (en) * | 2002-06-25 | 2006-04-11 | Aruna Nathan | Injectable microdispersions for medical applications |
US7101566B2 (en) * | 2002-06-28 | 2006-09-05 | Ethicon, Inc. | Polymer coated microparticles for sustained release |
WO2004030631A2 (en) | 2002-10-01 | 2004-04-15 | Chiron Corporation | Anti-cancer and anti-infectious disease compositions and methods for using same |
US6872799B2 (en) | 2002-12-18 | 2005-03-29 | Ethicon, Inc. | Functionalized polymers for medical applications |
US6866860B2 (en) | 2002-12-19 | 2005-03-15 | Ethicon, Inc. | Cationic alkyd polyesters for medical applications |
US20040120981A1 (en) * | 2002-12-20 | 2004-06-24 | Aruna Nathan | Crosslinked alkyd polyesters for medical applications |
JP2006523613A (ja) * | 2002-12-20 | 2006-10-19 | エスティ.ジェイムス アソシエイト エルエルシー/フェイバー リサーチ シリーズ | 徐放性医薬投与のための被覆粒子 |
US7060299B2 (en) * | 2002-12-31 | 2006-06-13 | Battelle Memorial Institute | Biodegradable microparticles that stabilize and control the release of proteins |
JP2009513493A (ja) * | 2003-06-26 | 2009-04-02 | メディオラニューム ファーマシューティカルス リミテッド | 制限された活性成分の初期放出を有し、続いてその徐放性を直線的に変化させる皮下インプラント |
TWI357815B (en) * | 2003-06-27 | 2012-02-11 | Euro Celtique Sa | Multiparticulates |
WO2005035088A2 (en) * | 2003-07-18 | 2005-04-21 | Baxter International, Inc. | Method for preparing small spherical by controlled phase separation |
US20070092452A1 (en) * | 2003-07-18 | 2007-04-26 | Julia Rashba-Step | Methods for fabrication, uses, compositions of inhalable spherical particles |
US20050142205A1 (en) * | 2003-07-18 | 2005-06-30 | Julia Rashba-Step | Methods for encapsulating small spherical particles prepared by controlled phase separation |
CA2532874A1 (en) * | 2003-07-22 | 2005-02-03 | Baxter International Inc. | Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof |
KR100453273B1 (ko) * | 2003-09-04 | 2004-10-15 | 주식회사 펩트론 | 초음파 이중공급노즐을 이용한 서방성 미립구의 제조 방법 |
US7456254B2 (en) * | 2004-04-15 | 2008-11-25 | Alkermes, Inc. | Polymer-based sustained release device |
US20060110423A1 (en) * | 2004-04-15 | 2006-05-25 | Wright Steven G | Polymer-based sustained release device |
US8617613B2 (en) | 2004-04-15 | 2013-12-31 | Alkermes Pharma Ireland Limited | Polymer-based sustained release device |
US8728525B2 (en) | 2004-05-12 | 2014-05-20 | Baxter International Inc. | Protein microspheres retaining pharmacokinetic and pharmacodynamic properties |
WO2005112885A2 (en) * | 2004-05-12 | 2005-12-01 | Baxter International Inc. | Oligonucleotide-containing microspheres, their use for the manufacture of a medicament for treating diabetes type 1 |
ATE409025T1 (de) | 2004-05-12 | 2008-10-15 | Baxter Int | Nukleinsäure-mikrokügelchen, ihre herstellung und abgabe |
US8333995B2 (en) | 2004-05-12 | 2012-12-18 | Baxter International, Inc. | Protein microspheres having injectable properties at high concentrations |
EP1824460B1 (en) * | 2004-11-10 | 2014-12-24 | Tolmar Therapeutics, Inc. | A stabilized polymeric delivery system |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
US8318210B2 (en) | 2005-02-28 | 2012-11-27 | Neos Therapeutics, Lp | Compositions and methods of making sustained release liquid formulations |
US20060260777A1 (en) * | 2005-04-27 | 2006-11-23 | Julia Rashba-Step | Surface-modified microparticles and methods of forming and using the same |
US8017152B2 (en) * | 2005-05-27 | 2011-09-13 | Stratosphere Pharma Ab | Cores and microcapsules suitable for parenteral administration as well as process for their manufacture |
EP1726299A3 (en) | 2005-05-27 | 2007-04-18 | StratoSphere Pharma AB | Cores and microcapsules suitable for parenteral administration as well as process for their manufacture |
EP1931387A4 (en) * | 2005-09-07 | 2012-07-11 | Southwest Res Inst | BIODEGRADABLE MICROTEILED PHARMACEUTICAL FORMULATIONS WITH IMPROVED RELEASE RATES |
US9693967B2 (en) | 2005-09-07 | 2017-07-04 | Southwest Research Institute | Biodegradable microparticle pharmaceutical formulations exhibiting improved released rates |
US20070092553A1 (en) * | 2005-10-21 | 2007-04-26 | Pfab Lp | Compositions and methods of making rapidly dissolving lonically masked formulations |
US20080286375A1 (en) * | 2005-11-15 | 2008-11-20 | Amorepacific Corporation | Method for Preparing Sustained-Release Microparticles Comprising Sucrose Acetate Isobutyrate |
GB0602897D0 (en) * | 2006-02-13 | 2006-03-22 | Jagotec Ag | Improvements In Or Relating To Dry Powder Inhaler Devices |
US20070281031A1 (en) * | 2006-06-01 | 2007-12-06 | Guohan Yang | Microparticles and methods for production thereof |
JP5118139B2 (ja) | 2006-08-04 | 2013-01-16 | バクスター・インターナショナル・インコーポレイテッド | 新規発症自己免疫性糖尿病を予防および/または逆転させるためのマイクロスフィアに基づく組成物 |
DK2049081T3 (da) | 2006-08-09 | 2013-02-25 | Intarcia Therapeutics Inc | Osmotiske leveringssystemer og stempelarrangementer |
MX2009003661A (es) * | 2006-10-06 | 2009-04-22 | Baxter Int | Microcapsulas que contienen microparticulas modificadas en la superficie y metodos para formar y utilizar las mismas. |
GB0622818D0 (en) * | 2006-11-15 | 2006-12-27 | Jagotec Ag | Improvements in or relating to organic compounds |
GB0625303D0 (en) * | 2006-12-19 | 2007-01-24 | Jagotec Ag | Improvements in and relating to metered dose inhalers |
AU2008231093A1 (en) * | 2007-03-22 | 2008-10-02 | Alkermes, Inc. | Coacervation process |
GB0707612D0 (en) | 2007-04-19 | 2007-05-30 | Stratosphere Pharma Ab | Cores and microcapsules suitable for parenteral administration as well as process for their manufacture |
ES2402172T3 (es) | 2007-04-23 | 2013-04-29 | Intarcia Therapeutics, Inc | Formulación en suspensión de péptidos insulinotrópicos y usos de los mismos |
JP2010529040A (ja) * | 2007-05-30 | 2010-08-26 | ネオス・セラピューティクス・エルピー | イオン性樹脂系の懸濁液における薬物放出の調節 |
US20080317865A1 (en) * | 2007-06-20 | 2008-12-25 | Alkermes, Inc. | Quench liquids and washing systems for production of microparticles |
WO2009102467A2 (en) | 2008-02-13 | 2009-08-20 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
US8323615B2 (en) | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing multi-phasic dispersions |
US8323685B2 (en) | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing compositions containing microparticles |
US8367427B2 (en) | 2008-08-20 | 2013-02-05 | Baxter International Inc. | Methods of processing compositions containing microparticles |
LT2462246T (lt) | 2009-09-28 | 2017-11-27 | Intarcia Therapeutics, Inc | Esminio stacionaraus vaisto tiekimo greitas įgyvendinimas ir (arba) nutraukimas |
KR101331136B1 (ko) | 2011-01-12 | 2013-11-26 | 아주대학교산학협력단 | 약물의 초기 과다 방출 제어를 위한 약물전달 제형 및 이의 제조방법 |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
BR112015024234B1 (pt) | 2013-03-21 | 2022-11-16 | Eupraxia Pharmaceuticals USA LLC | Composição farmacêutica de liberação sustentada injetável, uso da mesma para diminuir inflamação ou controlar dor e método para formar micropartículas revestidas |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
AU2016270984B2 (en) | 2015-06-03 | 2021-02-25 | Intarcia Therapeutics, Inc. | Implant placement and removal systems |
TR201808237T4 (tr) | 2015-10-27 | 2018-07-23 | Eupraxia Pharmaceuticals Inc | Lokal anestetiklerin sürekli salım formülasyonları. |
TWI814219B (zh) | 2016-05-16 | 2023-09-01 | 美商因塔希亞治療公司 | 升糖素受體選擇性多肽和彼之使用方法 |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
IL267736B2 (en) | 2017-01-03 | 2024-03-01 | Intarcia Therapeutics Inc | Methods involving continuous administration of a GLP-1 receptor agonist and co-administration of a drug |
KR102383448B1 (ko) * | 2020-04-20 | 2022-04-06 | 한국화학연구원 | 락트산 또는 글리콜산을 포함하는 미립구형 서방출 제제 및 그의 제조방법 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3117027A (en) * | 1960-01-08 | 1964-01-07 | Wisconsin Alumni Res Found | Apparatus for coating particles in a fluidized bed |
US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US4384975A (en) * | 1980-06-13 | 1983-05-24 | Sandoz, Inc. | Process for preparation of microspheres |
US4479911A (en) * | 1982-01-28 | 1984-10-30 | Sandoz, Inc. | Process for preparation of microspheres and modification of release rate of core material |
US4637905A (en) * | 1982-03-04 | 1987-01-20 | Batelle Development Corporation | Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or ε-caprolactones |
CH661206A5 (fr) * | 1983-09-23 | 1987-07-15 | Debiopharm Sa | Procede pour la preparation d'un medicament destine au traitement de maladies hormonodependantes. |
US4568559A (en) * | 1984-02-06 | 1986-02-04 | Biotek, Inc. | Composite core coated microparticles and process of preparing same |
US4623588A (en) * | 1984-02-06 | 1986-11-18 | Biotek, Inc. | Controlled release composite core coated microparticles |
CA1236641A (en) * | 1984-07-06 | 1988-05-10 | Motoaki Tanaka | Copolymer of lactic acid and glycolic acid and method for producing same |
JP2551756B2 (ja) * | 1985-05-07 | 1996-11-06 | 武田薬品工業株式会社 | ポリオキシカルボン酸エステルおよびその製造法 |
US4666704A (en) * | 1985-05-24 | 1987-05-19 | International Minerals & Chemical Corp. | Controlled release delivery system for macromolecules |
SE459005B (sv) * | 1985-07-12 | 1989-05-29 | Aake Rikard Lindahl | Saett att framstaella sfaeriska polymerpartiklar |
CA1309022C (en) * | 1986-04-07 | 1992-10-20 | Richard James Harwood | Method for the preparation of a sustained release pharmaceutical composition and the composition prepared thereby |
SE8701479L (sv) * | 1987-04-09 | 1988-10-10 | Carbomatrix Ab | Metod foer inneslutning av biologiskt verksamma preparat samt anvaendning daerav |
US5019397A (en) * | 1988-04-21 | 1991-05-28 | Alza Corporation | Aqueous emulsion for pharmaceutical dosage form |
US5275819A (en) * | 1989-02-06 | 1994-01-04 | Amer Particle Technologies Inc. | Drug loaded pollen grains with an outer coating for pulsed delivery |
US5019400A (en) * | 1989-05-01 | 1991-05-28 | Enzytech, Inc. | Very low temperature casting of controlled release microspheres |
EP0550436A1 (en) * | 1989-11-06 | 1993-07-14 | Alkermes Controlled Therapeutics, Inc. | Protein microspheres and methods of using them |
FR2663207B1 (fr) * | 1990-06-15 | 1993-04-30 | Rhone Poulenc Nutrition Animal | Procede d'enrobage par un polymere ph sensible de principes actifs. |
EP0576675A4 (en) * | 1991-03-25 | 1994-06-01 | Fujisawa Pharmaceutical Co | Long-acting pharmaceutical preparation |
DE69220317T2 (de) * | 1991-10-01 | 1997-10-16 | Takeda Chemical Industries Ltd | Mikropartikeln-Zusammenfassung zur verlängerten Freigabe und Herstellung derselbe |
US5288502A (en) * | 1991-10-16 | 1994-02-22 | The University Of Texas System | Preparation and uses of multi-phase microspheres |
PT674506E (pt) * | 1992-12-02 | 2001-01-31 | Alkermes Inc | Microsferas contendo hormona de crescimento com libertacao controlada |
US5417982A (en) * | 1994-02-17 | 1995-05-23 | Modi; Pankaj | Controlled release of drugs or hormones in biodegradable polymer microspheres |
-
1995
- 1995-10-19 SE SE9503672A patent/SE505146C2/sv not_active IP Right Cessation
-
1996
- 1996-09-03 ES ES01117830T patent/ES2267637T3/es not_active Expired - Lifetime
- 1996-09-03 IL IL12405296A patent/IL124052A/xx not_active IP Right Cessation
- 1996-09-03 EP EP06010350A patent/EP1716849A1/en not_active Withdrawn
- 1996-09-03 US US09/051,709 patent/US6120787A/en not_active Expired - Fee Related
- 1996-09-03 EP EP01117830A patent/EP1142569B1/en not_active Expired - Lifetime
- 1996-09-03 ES ES96935641T patent/ES2125209T3/es not_active Expired - Lifetime
- 1996-09-03 PT PT96935641T patent/PT869774E/pt unknown
- 1996-09-03 WO PCT/SE1996/001091 patent/WO1997014408A1/en active IP Right Grant
- 1996-09-03 JP JP9515728A patent/JP2000501380A/ja active Pending
- 1996-09-03 KR KR1019980702757A patent/KR100482262B1/ko not_active IP Right Cessation
- 1996-09-03 DK DK96935641T patent/DK0869774T3/da active
- 1996-09-03 EP EP96935641A patent/EP0869774B1/en not_active Expired - Lifetime
- 1996-09-03 AT AT96935641T patent/ATE228826T1/de not_active IP Right Cessation
- 1996-09-03 DE DE0869774T patent/DE869774T1/de active Pending
- 1996-09-03 DE DE69636177T patent/DE69636177T2/de not_active Expired - Fee Related
- 1996-09-03 HU HU9901205A patent/HUP9901205A3/hu unknown
- 1996-09-03 CZ CZ19981173A patent/CZ293059B6/cs not_active IP Right Cessation
- 1996-09-03 AT AT01117830T patent/ATE326953T1/de not_active IP Right Cessation
- 1996-09-03 DE DE69625240T patent/DE69625240T2/de not_active Expired - Fee Related
- 1996-09-03 AU AU73478/96A patent/AU699080B2/en not_active Ceased
-
1998
- 1998-04-06 NO NO19981558A patent/NO320392B1/no unknown
- 1998-11-16 HK HK98112027A patent/HK1011182A1/xx not_active IP Right Cessation
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