DK0785948T3 - Analoger af keratinocyt vækstfaktor - Google Patents

Analoger af keratinocyt vækstfaktor

Info

Publication number: DK0785948T3
Authority: DK; Denmark
Prior art keywords: growth factor; analogues; keratinocyte growth; keratinocyte; mammals
Prior art date: 1994-10-13

Application number

DK95934793T

Other languages

English (en)

Inventor

Charles F Morris

William C Kenney

Bao-Lu Chen

Eric W Hsu

Original Assignee

Amgen Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-13

Filing date

1995-10-12

Publication date

2003-08-04

1995-10-12 Application filed by Amgen Inc filed Critical Amgen Inc

2003-08-04 Application granted granted Critical

2003-08-04 Publication of DK0785948T3 publication Critical patent/DK0785948T3/da

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factors [FGF]

DK95934793T 1994-10-13 1995-10-12 Analoger af keratinocyt vækstfaktor DK0785948T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US32334094A	1994-10-13	1994-10-13
US32347594A	1994-10-13	1994-10-13
US48782595A	1995-06-07	1995-06-07
PCT/IB1995/000971 WO1996011949A2 (en)	1994-10-13	1995-10-12	Analogs of keratinocyte growth factor

Publications (1)

Publication Number	Publication Date
DK0785948T3 true DK0785948T3 (da)	2003-08-04

Family

ID=27406268

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK95934793T DK0785948T3 (da)	1994-10-13	1995-10-12	Analoger af keratinocyt vækstfaktor
DK95934808T DK0804479T3 (da)	1994-10-13	1995-10-12	Fremgangsmåde til behandling af diabetes mellitus ved anvendelse af KGF

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK95934808T DK0804479T3 (da)	1994-10-13	1995-10-12	Fremgangsmåde til behandling af diabetes mellitus ved anvendelse af KGF

Country Status (23)

Country	Link
EP (2)	EP0804479B1 (da)
JP (2)	JP4426646B2 (da)
KR (1)	KR100278597B1 (da)
CN (1)	CN1168678A (da)
AT (2)	ATE342278T1 (da)
AU (1)	AU3707795A (da)
BG (2)	BG101392A (da)
BR (2)	BR9509329A (da)
CA (2)	CA2201940C (da)
CZ (3)	CZ297328B6 (da)
DE (2)	DE69535264T2 (da)
DK (2)	DK0785948T3 (da)
EE (2)	EE9700225A (da)
ES (2)	ES2273338T3 (da)
FI (2)	FI971420A0 (da)
HU (2)	HU226168B1 (da)
NO (2)	NO318761B1 (da)
NZ (2)	NZ505502A (da)
PL (2)	PL182888B1 (da)
PT (2)	PT804479E (da)
SI (2)	SI0785948T1 (da)
SK (2)	SK284534B6 (da)
WO (2)	WO1996011950A1 (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2250213C2 (ru)	1989-01-31	2005-04-20	Джеффри С. РУБИН	Выделенный белок фактора роста кератиноцита (kgf), рекомбинантная молекула днк, вектор, способ конструирования клетки-хозяина, способ получения белка, фармацевтическая композиция
US7084119B2 (en)	1993-06-29	2006-08-01	Chiron Corporation	Truncated keratinocyte growth factor (KGF) having increased biological activity
CA2166278A1 (en)	1993-06-29	1995-01-12	Denis J. Gospodarowicz	A truncated keratinocyte growth factor (kgf) having increased biological activity
HU220584B1 (hu) *	1994-10-13	2002-03-28	Amgen Inc.	A keratinocita növekedési faktorok tisztítására szolgáló módszer
US6693077B1 (en)	1995-02-14	2004-02-17	Human Genome Sciences, Inc.	Keratinocyte growth factor-2
US6077692A (en)	1995-02-14	2000-06-20	Human Genome Sciences, Inc.	Keratinocyte growth factor-2
US7232667B2 (en)	1995-02-14	2007-06-19	Human Genome Sciences, Inc.	Keratinocyte growth factor-2 polynucleotides
WO1996034017A1 (en) *	1995-04-27	1996-10-31	Coöperatie Suiker Unie U.A.	Inulin derivatives
EP1473366A1 (en) *	1996-10-15	2004-11-03	Amgen Inc.	Keratinocyte growth factor-2 products
ES2218666T3 (es) *	1996-10-15	2004-11-16	Amgen Inc.,	Producto a base del factor de crecimiento de queratinocitos-2 (kggf-2).
US6743422B1 (en)	1996-10-15	2004-06-01	Amgen, Inc.	Keratinocyte growth factor-2 products
US7495087B2 (en)	1997-07-14	2009-02-24	Bolder Biotechnology, Inc.	Cysteine muteins in the C-D loop of human interleukin-11
WO1999003887A1 (en)	1997-07-14	1999-01-28	Bolder Biotechnology, Inc.	Derivatives of growth hormone and related proteins
US20080076706A1 (en)	1997-07-14	2008-03-27	Bolder Biotechnology, Inc.	Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof
US7153943B2 (en)	1997-07-14	2006-12-26	Bolder Biotechnology, Inc.	Derivatives of growth hormone and related proteins, and methods of use thereof
US6869927B1 (en)	1997-12-22	2005-03-22	Human Genome Sciences, Inc.	Keratinocyte growth factor-2 formulations
JP2001526239A (ja)	1997-12-22	2001-12-18	ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド	角質細胞増殖因子−２製剤
US6242666B1 (en) *	1998-12-16	2001-06-05	The Scripps Research Institute	Animal model for identifying a common stem/progenitor to liver cells and pancreatic cells
ATE526401T1 (de) *	1999-01-14	2011-10-15	Bolder Biotechnology Inc	Verfahren zur herstellung von proteinen mit freien cysteinresten
US8288126B2 (en)	1999-01-14	2012-10-16	Bolder Biotechnology, Inc.	Methods for making proteins containing free cysteine residues
US6248725B1 (en)	1999-02-23	2001-06-19	Amgen, Inc.	Combinations and methods for promoting in vivo liver cell proliferation and enhancing in vivo liver-directed gene transduction
MXPA03006988A (es) *	2001-02-06	2003-11-18	Merck Patent Gmbh	Factor de crecimiento de queratinocitos (kgf) modificado con inmunogenicidad reducida.
AU2007214362B2 (en) *	2001-08-21	2009-11-26	Novartis Vaccines And Diagnostics, Inc.	KGF polypeptide compositions
AU2002326742B2 (en) *	2001-08-21	2007-05-31	Novartis Vaccines And Diagnostics, Inc.	KGF polypeptide compositions
ES2504441T3 (es)	2004-12-15	2014-10-08	Swedish Orphan Biovitrum Ab (Publ)	Formulaciones terapéuticas del factor de crecimiento de queratinocitos
CN102242124B (zh) *	2010-05-10	2013-05-22	齐鲁制药有限公司	改造的角化细胞生长因子基因及其在酵母中的表达
KR102440312B1 (ko) *	2020-08-28	2022-09-05	한국해양과학기술원	온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4959314A (en) *	1984-11-09	1990-09-25	Cetus Corporation	Cysteine-depleted muteins of biologically active proteins
JPH01137994A (ja) *	1987-08-10	1989-05-30	Shionogi & Co Ltd	ｒｅｇ蛋白質
CA1306456C (en) *	1988-07-27	1992-08-18	Marjan International Pty. Ltd.	Carpet stretcher
RU2250213C2 (ru) *	1989-01-31	2005-04-20	Джеффри С. РУБИН	Выделенный белок фактора роста кератиноцита (kgf), рекомбинантная молекула днк, вектор, способ конструирования клетки-хозяина, способ получения белка, фармацевтическая композиция
JP3303211B2 (ja) *	1991-04-26	2002-07-15	武田薬品工業株式会社	ｂＦＧＦムテインおよびその製造法
CZ285996B6 (cs) *	1993-03-26	1999-12-15	Amgen Inc.	Způsob in vitro stimulace produkce nekeratinocytových epithelových buněk a růstový faktor keratinocytů pro léčbu chorob
US5348563A (en) *	1993-06-29	1994-09-20	Honeywell Inc.	Air purifying apparatus
CA2166278A1 (en) *	1993-06-29	1995-01-12	Denis J. Gospodarowicz	A truncated keratinocyte growth factor (kgf) having increased biological activity
GB9315501D0 (en) *	1993-07-27	1993-09-08	Ici Plc	Surfactant compositions
AU7475694A (en) *	1993-08-02	1995-02-28	Prizm Pharmaceuticals, Inc.	Monogenous preparations of cytotoxic conjugates

1995
- 1995-10-12 CA CA002201940A patent/CA2201940C/en not_active Expired - Fee Related
- 1995-10-12 CN CN95196410A patent/CN1168678A/zh active Pending
- 1995-10-12 KR KR1019970702343A patent/KR100278597B1/ko not_active IP Right Cessation
- 1995-10-12 BR BR9509329A patent/BR9509329A/pt not_active Application Discontinuation
- 1995-10-12 EP EP95934808A patent/EP0804479B1/en not_active Expired - Lifetime
- 1995-10-12 DK DK95934793T patent/DK0785948T3/da active
- 1995-10-12 AT AT95934808T patent/ATE342278T1/de active
- 1995-10-12 PT PT95934808T patent/PT804479E/pt unknown
- 1995-10-12 CZ CZ0105097A patent/CZ297328B6/cs not_active IP Right Cessation
- 1995-10-12 EE EE9700225A patent/EE9700225A/xx unknown
- 1995-10-12 DE DE69535264T patent/DE69535264T2/de not_active Expired - Lifetime
- 1995-10-12 AT AT95934793T patent/ATE237633T1/de active
- 1995-10-12 ES ES95934808T patent/ES2273338T3/es not_active Expired - Lifetime
- 1995-10-12 PT PT95934793T patent/PT785948E/pt unknown
- 1995-10-12 AU AU37077/95A patent/AU3707795A/en not_active Abandoned
- 1995-10-12 PL PL95319784A patent/PL182888B1/pl not_active IP Right Cessation
- 1995-10-12 EE EE9700081A patent/EE03975B1/xx not_active IP Right Cessation
- 1995-10-12 SK SK455-97A patent/SK284534B6/sk not_active IP Right Cessation
- 1995-10-12 JP JP51307696A patent/JP4426646B2/ja not_active Expired - Fee Related
- 1995-10-12 HU HU9901255A patent/HU226168B1/hu not_active IP Right Cessation
- 1995-10-12 WO PCT/IB1995/000992 patent/WO1996011950A1/en active IP Right Grant
- 1995-10-12 CA CA002202075A patent/CA2202075C/en not_active Expired - Fee Related
- 1995-10-12 ES ES95934793T patent/ES2196082T3/es not_active Expired - Lifetime
- 1995-10-12 SI SI9530654T patent/SI0785948T1/xx unknown
- 1995-10-12 PL PL95320484A patent/PL320484A1/xx unknown
- 1995-10-12 SK SK431-97A patent/SK43197A3/sk unknown
- 1995-10-12 JP JP51307796A patent/JP4216329B2/ja not_active Expired - Fee Related
- 1995-10-12 HU HU9901071A patent/HUT78050A/hu unknown
- 1995-10-12 DK DK95934808T patent/DK0804479T3/da active
- 1995-10-12 BR BR9509269A patent/BR9509269A/pt not_active Application Discontinuation
- 1995-10-12 SI SI9530728T patent/SI0804479T1/sl unknown
- 1995-10-12 EP EP95934793A patent/EP0785948B1/en not_active Expired - Lifetime
- 1995-10-12 DE DE69530403T patent/DE69530403T2/de not_active Expired - Lifetime
- 1995-10-12 CZ CZ20023953A patent/CZ297329B6/cs not_active IP Right Cessation
- 1995-10-12 CZ CZ97981A patent/CZ98197A3/cs unknown
- 1995-10-12 NZ NZ505502A patent/NZ505502A/en not_active IP Right Cessation
- 1995-10-12 WO PCT/IB1995/000971 patent/WO1996011949A2/en active IP Right Grant
1997
- 1997-04-04 FI FI971420A patent/FI971420A0/fi unknown
- 1997-04-04 NO NO19971568A patent/NO318761B1/no not_active IP Right Cessation
- 1997-04-04 NO NO971566A patent/NO971566L/no unknown
- 1997-04-07 BG BG101392A patent/BG101392A/xx unknown
- 1997-04-11 BG BG101408A patent/BG63167B1/bg unknown
- 1997-04-11 FI FI971536A patent/FI120040B/fi not_active IP Right Cessation
1999
- 1999-04-09 NZ NZ335109A patent/NZ335109A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI971536A (fi)	1997-06-09
WO1996011949A2 (en)	1996-04-25
DE69535264T2 (de)	2007-02-01
BG101392A (en)	1997-10-31
DE69535264D1 (de)	2006-11-23
HUT78058A (hu)	1999-07-28
NO318761B1 (no)	2005-05-02
JPH10507193A (ja)	1998-07-14
CA2202075C (en)	2003-12-09
FI120040B (fi)	2009-06-15
BG101408A (en)	1997-12-30
SK284534B6 (sk)	2005-06-02
JP4216329B2 (ja)	2009-01-28
EP0785948A1 (en)	1997-07-30
CZ297329B6 (cs)	2006-11-15
FI971420A (fi)	1997-04-04
EP0804479B1 (en)	2006-10-11
FI971536A0 (fi)	1997-04-11
SI0804479T1 (sl)	2006-12-31
PT804479E (pt)	2007-02-28
PL320484A1 (en)	1997-09-29
CA2202075A1 (en)	1996-04-25
DK0804479T3 (da)	2007-01-29
AU3707795A (en)	1996-05-06
FI971420A0 (fi)	1997-04-04
JP4426646B2 (ja)	2010-03-03
CA2201940C (en)	2009-05-12
BR9509329A (pt)	1997-10-14
NZ505502A (en)	2005-01-28
WO1996011949A3 (en)	1996-12-12
AU3708395A (en)	1996-05-06
PL182888B1 (pl)	2002-03-29
SK45597A3 (en)	1999-02-11
BG63167B1 (bg)	2001-05-31
ATE342278T1 (de)	2006-11-15
WO1996011950A1 (en)	1996-04-25
BR9509269A (pt)	1997-12-23
KR100278597B1 (ko)	2001-01-15
SK43197A3 (en)	1999-03-12
EE9700225A (et)	1998-02-16
JPH10507080A (ja)	1998-07-14
PL319784A1 (en)	1997-08-18
EE9700081A (et)	1997-10-15
NO971566L (no)	1997-04-14
ES2273338T3 (es)	2007-05-01
NZ335109A (en)	2000-08-25
DE69530403D1 (de)	2003-05-22
NO971568L (no)	1997-06-12
SI0785948T1 (en)	2003-08-31
CZ98197A3 (cs)	1998-11-11
AU681546B2 (en)	1997-08-28
EP0785948B1 (en)	2003-04-16
CZ297328B6 (cs)	2006-11-15
CN1168678A (zh)	1997-12-24
ES2196082T3 (es)	2003-12-16
NO971568D0 (no)	1997-04-04
EE03975B1 (et)	2003-02-17
ATE237633T1 (de)	2003-05-15
NO971566D0 (no)	1997-04-04
DE69530403T2 (de)	2003-10-30
CZ105097A3 (cs)	1998-10-14
PT785948E (pt)	2003-09-30
CA2201940A1 (en)	1996-04-25
HUT78050A (hu)	1999-07-28
HU226168B1 (en)	2008-05-28
EP0804479A1 (en)	1997-11-05

Publication	Publication Date	Title
DK0785948T3 (da)	2003-08-04	Analoger af keratinocyt vækstfaktor
TR200100922T2 (tr)	2001-09-21	Aktif maddelerin akciğerler yolu ile tatbik edilmesi.
ES2186783T3 (es)	2003-05-16	Derivados de la dolastatina, su preparacion y uso.
ES2194106T3 (es)	2003-11-16	.ompuestos de imidazol
BR8907538A (pt)	1991-06-11	Processo e composicao de tecido para enxertos
FI973828A (fi)	1997-09-29	Yhdisteitä ja koostumuksia aktiivisten aineiden annostelemiseksi
ATE176383T1 (de)	1999-02-15	Dermal applizierbare formulierungen von parasitiziden
DE69630955D1 (de)	2004-01-15	Immortalisierung bzw. desimmortalisierung von zellen
DE69405919D1 (de)	1997-11-06	Zusammensetzungen zur Behandlung von Keratinfasern
MX9704050A (es)	1997-08-30	P-amidinobencilamidas de dipeptido novedosas con radicales sulfonilo o aminosulfonilo en terminal n.
DE69111768T2 (de)	1995-12-21	Enzymatische Zusammensetzung zur Bestimmung von Äthanol.
DE69824862D1 (de)	2004-08-05	Zusammenstellungen zur verbesserten wundheilung
ECSP961819A (es)	1997-11-04	Nuevos inhibidores de farnesil-transferasa, su preparacion y las composiciones farmaceuticas que contienen (caso st 95042)
KR900011870A (ko)	1990-08-02	혐기성 조성물
DE9411558U1 (de)	1994-10-06	Anordnung zur Sprachausgabe
ES273731Y (es)	1984-07-16	Instrumento aplicador de inyecciones para anestesia en odontologia.