FI971536A0 - Keratinosyytti-kasvutekijän analogeja - Google Patents

Keratinosyytti-kasvutekijän analogeja

Info

Publication number
FI971536A0
FI971536A0 FI971536A FI971536A FI971536A0 FI 971536 A0 FI971536 A0 FI 971536A0 FI 971536 A FI971536 A FI 971536A FI 971536 A FI971536 A FI 971536A FI 971536 A0 FI971536 A0 FI 971536A0
Authority
FI
Finland
Prior art keywords
growth factor
analogues
keratinocyte growth
keratinocyte
mammals
Prior art date
Application number
FI971536A
Other languages
English (en)
Swedish (sv)
Other versions
FI120040B (fi
FI971536A (fi
Inventor
Charles F Morris
William C Kenney
Bao-Lu Chen
Eric W Hsu
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of FI971536A0 publication Critical patent/FI971536A0/fi
Publication of FI971536A publication Critical patent/FI971536A/fi
Application granted granted Critical
Publication of FI120040B publication Critical patent/FI120040B/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1825Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI971536A 1994-10-13 1997-04-11 Keratinosyytti-kasvutekijän analogeja FI120040B (fi)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US32347594A 1994-10-13 1994-10-13
US32334094A 1994-10-13 1994-10-13
US32347594 1994-10-13
US32334094 1994-10-13
US48782595A 1995-06-07 1995-06-07
US48782595 1995-06-07
IB9500992 1995-10-12
PCT/IB1995/000992 WO1996011950A1 (en) 1994-10-13 1995-10-12 Method of treating diabetes mellitus using kgf

Publications (3)

Publication Number Publication Date
FI971536A0 true FI971536A0 (fi) 1997-04-11
FI971536A FI971536A (fi) 1997-06-09
FI120040B FI120040B (fi) 2009-06-15

Family

ID=27406268

Family Applications (2)

Application Number Title Priority Date Filing Date
FI971420A FI971420A0 (fi) 1994-10-13 1997-04-04 Menetelmä diabetes mellituksen hoitamiseksi KGF:ää käyttämällä
FI971536A FI120040B (fi) 1994-10-13 1997-04-11 Keratinosyytti-kasvutekijän analogeja

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI971420A FI971420A0 (fi) 1994-10-13 1997-04-04 Menetelmä diabetes mellituksen hoitamiseksi KGF:ää käyttämällä

Country Status (23)

Country Link
EP (2) EP0785948B1 (fi)
JP (2) JP4216329B2 (fi)
KR (1) KR100278597B1 (fi)
CN (1) CN1168678A (fi)
AT (2) ATE237633T1 (fi)
AU (1) AU3707795A (fi)
BG (2) BG101392A (fi)
BR (2) BR9509269A (fi)
CA (2) CA2202075C (fi)
CZ (3) CZ98197A3 (fi)
DE (2) DE69530403T2 (fi)
DK (2) DK0804479T3 (fi)
EE (2) EE9700225A (fi)
ES (2) ES2273338T3 (fi)
FI (2) FI971420A0 (fi)
HU (2) HUT78050A (fi)
NO (2) NO318761B1 (fi)
NZ (2) NZ505502A (fi)
PL (2) PL320484A1 (fi)
PT (2) PT804479E (fi)
SI (2) SI0804479T1 (fi)
SK (2) SK43197A3 (fi)
WO (2) WO1996011949A2 (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU647732B2 (en) 1989-01-31 1994-03-31 Stuart A. Aaronson DNA encoding a growth factor specific for epithelial cells
CN1129955A (zh) 1993-06-29 1996-08-28 奇龙公司 截短的生物活性更高的角质形成细胞生长因子
US7084119B2 (en) 1993-06-29 2006-08-01 Chiron Corporation Truncated keratinocyte growth factor (KGF) having increased biological activity
DK0785949T3 (da) * 1994-10-13 2003-08-18 Amgen Inc Fremgangsmåde til oprensning af keratinocytvækstfaktorer
US6693077B1 (en) 1995-02-14 2004-02-17 Human Genome Sciences, Inc. Keratinocyte growth factor-2
US7232667B2 (en) 1995-02-14 2007-06-19 Human Genome Sciences, Inc. Keratinocyte growth factor-2 polynucleotides
US6077692A (en) * 1995-02-14 2000-06-20 Human Genome Sciences, Inc. Keratinocyte growth factor-2
WO1996034017A1 (en) * 1995-04-27 1996-10-31 Coöperatie Suiker Unie U.A. Inulin derivatives
US6743422B1 (en) 1996-10-15 2004-06-01 Amgen, Inc. Keratinocyte growth factor-2 products
AU727678C (en) * 1996-10-15 2005-05-12 Biovitrum Ab (Publ) Keratinocyte growth factor-2 products
EP1473366A1 (en) * 1996-10-15 2004-11-03 Amgen Inc. Keratinocyte growth factor-2 products
US20080076706A1 (en) 1997-07-14 2008-03-27 Bolder Biotechnology, Inc. Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof
WO2000042175A1 (en) * 1999-01-14 2000-07-20 Bolder Biotechnology Inc. Methods for making proteins containing free cysteine residues
US7153943B2 (en) 1997-07-14 2006-12-26 Bolder Biotechnology, Inc. Derivatives of growth hormone and related proteins, and methods of use thereof
IL133974A0 (en) 1997-07-14 2001-04-30 Bolder Biotechnology Inc Derivatives of growth hormone and related proteins
US7495087B2 (en) 1997-07-14 2009-02-24 Bolder Biotechnology, Inc. Cysteine muteins in the C-D loop of human interleukin-11
US6869927B1 (en) 1997-12-22 2005-03-22 Human Genome Sciences, Inc. Keratinocyte growth factor-2 formulations
JP2001526239A (ja) 1997-12-22 2001-12-18 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド 角質細胞増殖因子−2製剤
US6242666B1 (en) * 1998-12-16 2001-06-05 The Scripps Research Institute Animal model for identifying a common stem/progenitor to liver cells and pancreatic cells
US8288126B2 (en) 1999-01-14 2012-10-16 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
US6248725B1 (en) 1999-02-23 2001-06-19 Amgen, Inc. Combinations and methods for promoting in vivo liver cell proliferation and enhancing in vivo liver-directed gene transduction
US20040063634A1 (en) * 2001-01-19 2004-04-01 Carr Francis J. Modified kertinocyte growth factor (kgf) with reduced immunogenicity
CA2457781A1 (en) * 2001-08-21 2003-02-27 Chiron Corporation Kgf polypeptide compositions
AU2007214362B2 (en) * 2001-08-21 2009-11-26 Novartis Vaccines And Diagnostics, Inc. KGF polypeptide compositions
PL1827483T3 (pl) 2004-12-15 2014-12-31 Swedish Orphan Biovitrum Ab Publ Formulacje terapeutyczne czynnika wzrostu keratynocytów
CN102242124B (zh) * 2010-05-10 2013-05-22 齐鲁制药有限公司 改造的角化细胞生长因子基因及其在酵母中的表达
KR102440312B1 (ko) * 2020-08-28 2022-09-05 한국해양과학기술원 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4959314A (en) * 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
JPH01137994A (ja) * 1987-08-10 1989-05-30 Shionogi & Co Ltd reg蛋白質
WO1990000877A1 (en) * 1988-07-27 1990-02-08 Marjan International Pty Ltd Carpet stretcher
AU647732B2 (en) * 1989-01-31 1994-03-31 Stuart A. Aaronson DNA encoding a growth factor specific for epithelial cells
JP3303211B2 (ja) * 1991-04-26 2002-07-15 武田薬品工業株式会社 bFGFムテインおよびその製造法
JP3578761B2 (ja) * 1993-03-26 2004-10-20 アムジエン・インコーポレーテツド 表皮ケラチン細胞成長因子の治療目的での使用
US5348563A (en) * 1993-06-29 1994-09-20 Honeywell Inc. Air purifying apparatus
CN1129955A (zh) * 1993-06-29 1996-08-28 奇龙公司 截短的生物活性更高的角质形成细胞生长因子
GB9315501D0 (en) * 1993-07-27 1993-09-08 Ici Plc Surfactant compositions
AU7475694A (en) * 1993-08-02 1995-02-28 Prizm Pharmaceuticals, Inc. Monogenous preparations of cytotoxic conjugates

Also Published As

Publication number Publication date
HUT78050A (hu) 1999-07-28
HU226168B1 (en) 2008-05-28
NO971566L (no) 1997-04-14
CZ297328B6 (cs) 2006-11-15
ES2273338T3 (es) 2007-05-01
CZ105097A3 (cs) 1998-10-14
EP0785948B1 (en) 2003-04-16
AU3707795A (en) 1996-05-06
DK0804479T3 (da) 2007-01-29
BG101392A (en) 1997-10-31
DE69535264T2 (de) 2007-02-01
FI971420A (fi) 1997-04-04
WO1996011949A2 (en) 1996-04-25
NZ505502A (en) 2005-01-28
CZ297329B6 (cs) 2006-11-15
EP0785948A1 (en) 1997-07-30
PT804479E (pt) 2007-02-28
ATE342278T1 (de) 2006-11-15
SI0804479T1 (sl) 2006-12-31
CZ98197A3 (cs) 1998-11-11
DE69535264D1 (de) 2006-11-23
NO971568D0 (no) 1997-04-04
JPH10507080A (ja) 1998-07-14
BG101408A (en) 1997-12-30
SK45597A3 (en) 1999-02-11
NO318761B1 (no) 2005-05-02
CN1168678A (zh) 1997-12-24
ES2196082T3 (es) 2003-12-16
FI120040B (fi) 2009-06-15
DE69530403D1 (de) 2003-05-22
SI0785948T1 (en) 2003-08-31
CA2202075C (en) 2003-12-09
DE69530403T2 (de) 2003-10-30
EE9700225A (et) 1998-02-16
EP0804479A1 (en) 1997-11-05
BR9509269A (pt) 1997-12-23
PL182888B1 (pl) 2002-03-29
ATE237633T1 (de) 2003-05-15
JP4216329B2 (ja) 2009-01-28
BR9509329A (pt) 1997-10-14
NO971566D0 (no) 1997-04-04
NO971568L (no) 1997-06-12
JP4426646B2 (ja) 2010-03-03
PT785948E (pt) 2003-09-30
EE9700081A (et) 1997-10-15
CA2201940A1 (en) 1996-04-25
JPH10507193A (ja) 1998-07-14
BG63167B1 (bg) 2001-05-31
FI971420A0 (fi) 1997-04-04
SK43197A3 (en) 1999-03-12
EP0804479B1 (en) 2006-10-11
EE03975B1 (et) 2003-02-17
FI971536A (fi) 1997-06-09
NZ335109A (en) 2000-08-25
HUT78058A (hu) 1999-07-28
PL320484A1 (en) 1997-09-29
PL319784A1 (en) 1997-08-18
AU3708395A (en) 1996-05-06
CA2202075A1 (en) 1996-04-25
CA2201940C (en) 2009-05-12
WO1996011950A1 (en) 1996-04-25
WO1996011949A3 (en) 1996-12-12
SK284534B6 (sk) 2005-06-02
KR100278597B1 (ko) 2001-01-15
AU681546B2 (en) 1997-08-28
DK0785948T3 (da) 2003-08-04

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