DK0759786T3 - Somatostatinbindende peptidmetal-chelatkonjugater - Google Patents

Somatostatinbindende peptidmetal-chelatkonjugater

Info

Publication number
DK0759786T3
DK0759786T3 DK95919827T DK95919827T DK0759786T3 DK 0759786 T3 DK0759786 T3 DK 0759786T3 DK 95919827 T DK95919827 T DK 95919827T DK 95919827 T DK95919827 T DK 95919827T DK 0759786 T3 DK0759786 T3 DK 0759786T3
Authority
DK
Denmark
Prior art keywords
agents
reagents
methods
imaging
preparing
Prior art date
Application number
DK95919827T
Other languages
English (en)
Inventor
Richard Dean
Original Assignee
Cis Bio Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cis Bio Int filed Critical Cis Bio Int
Application granted granted Critical
Publication of DK0759786T3 publication Critical patent/DK0759786T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008—Peptides; Proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK95919827T 1994-05-12 1995-05-12 Somatostatinbindende peptidmetal-chelatkonjugater DK0759786T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/241,625 US5783170A (en) 1991-11-27 1994-05-12 Peptide-metal chelate conjugates
PCT/US1995/006034 WO1995031221A1 (en) 1994-05-12 1995-05-12 Somatostatin binding peptide-metal chelate conjugates

Publications (1)

Publication Number Publication Date
DK0759786T3 true DK0759786T3 (da) 2007-01-29

Family

ID=22911488

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95919827T DK0759786T3 (da) 1994-05-12 1995-05-12 Somatostatinbindende peptidmetal-chelatkonjugater

Country Status (12)

Country Link
US (5) US5783170A (da)
EP (1) EP0759786B1 (da)
JP (1) JP3918157B2 (da)
CN (1) CN1078480C (da)
AT (1) ATE340594T1 (da)
AU (1) AU708797B2 (da)
DE (1) DE69535242T2 (da)
DK (1) DK0759786T3 (da)
ES (1) ES2274517T3 (da)
PT (1) PT759786E (da)
WO (1) WO1995031221A1 (da)
ZA (1) ZA953878B (da)

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US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
US5783170A (en) * 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
US6017512A (en) * 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
US6051206A (en) * 1994-06-03 2000-04-18 Diatide, Inc Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
US6713605B1 (en) * 1996-04-10 2004-03-30 Kansas State University Research Foundation Synthetic peptides that inhibit leukocyte superoxide anion production and/or attract leukocytes
US6685913B1 (en) 1999-03-09 2004-02-03 Thomas Jefferson University Lipid soluble radioactive metal chelates for tumor therapy
US6358491B1 (en) * 1999-08-27 2002-03-19 Berlex Laboratories, Inc. Somatostatin analogs
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US7019109B2 (en) * 2001-03-16 2006-03-28 The Salk Institute For Bilogical Studies SSTR1-selective analogs
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AU2003259172A1 (en) * 2002-07-24 2004-02-09 The Salk Institute For Biological Studies Receptor (sstr4)- selective somatostatin analogs
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Also Published As

Publication number Publication date
US5972308A (en) 1999-10-26
PT759786E (pt) 2007-01-31
AU708797B2 (en) 1999-08-12
AU2550095A (en) 1995-12-05
DE69535242D1 (de) 2006-11-09
US5965108A (en) 1999-10-12
EP0759786B1 (en) 2006-09-27
EP0759786A1 (en) 1997-03-05
US5981477A (en) 1999-11-09
CN1155248A (zh) 1997-07-23
JPH10500411A (ja) 1998-01-13
CN1078480C (zh) 2002-01-30
ATE340594T1 (de) 2006-10-15
US5985241A (en) 1999-11-16
JP3918157B2 (ja) 2007-05-23
ZA953878B (en) 1996-01-18
US5783170A (en) 1998-07-21
WO1995031221A1 (en) 1995-11-23
DE69535242T2 (de) 2007-05-16
ES2274517T3 (es) 2007-05-16

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