DK0753511T3 - 4-indol-1-ylsmørsyrederivater, deres fremstilling og deres anvendelse som inhibitorer af alfa 1-adrenerge receptorer og testosteron-5alfa-reduktaser - Google Patents

4-indol-1-ylsmørsyrederivater, deres fremstilling og deres anvendelse som inhibitorer af alfa 1-adrenerge receptorer og testosteron-5alfa-reduktaser

Info

Publication number
DK0753511T3
DK0753511T3 DK95913377T DK95913377T DK0753511T3 DK 0753511 T3 DK0753511 T3 DK 0753511T3 DK 95913377 T DK95913377 T DK 95913377T DK 95913377 T DK95913377 T DK 95913377T DK 0753511 T3 DK0753511 T3 DK 0753511T3
Authority
DK
Denmark
Prior art keywords
lower alkyl
alpha
reductases
represents hydrogen
testosterone
Prior art date
Application number
DK95913377T
Other languages
English (en)
Inventor
Kiyoshi Yoshida
Tadashi Kurimoto
Mineo Takei
Hiroki Sato
Original Assignee
Zeria Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeria Pharm Co Ltd filed Critical Zeria Pharm Co Ltd
Application granted granted Critical
Publication of DK0753511T3 publication Critical patent/DK0753511T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK95913377T 1994-03-30 1995-03-29 4-indol-1-ylsmørsyrederivater, deres fremstilling og deres anvendelse som inhibitorer af alfa 1-adrenerge receptorer og testosteron-5alfa-reduktaser DK0753511T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8262094 1994-03-30
PCT/JP1995/000599 WO1995026955A1 (fr) 1994-03-30 1995-03-29 Derive d'indole et medicament le contenant

Publications (1)

Publication Number Publication Date
DK0753511T3 true DK0753511T3 (da) 2001-09-24

Family

ID=13779508

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95913377T DK0753511T3 (da) 1994-03-30 1995-03-29 4-indol-1-ylsmørsyrederivater, deres fremstilling og deres anvendelse som inhibitorer af alfa 1-adrenerge receptorer og testosteron-5alfa-reduktaser

Country Status (14)

Country Link
US (1) US5760040A (da)
EP (1) EP0753511B1 (da)
KR (1) KR100349634B1 (da)
CN (1) CN1067985C (da)
AT (1) ATE203012T1 (da)
AU (1) AU681021B2 (da)
CA (1) CA2186499A1 (da)
DE (1) DE69521687T2 (da)
DK (1) DK0753511T3 (da)
ES (1) ES2160158T3 (da)
GR (1) GR3036735T3 (da)
PT (1) PT753511E (da)
UY (1) UY25970A1 (da)
WO (1) WO1995026955A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1135558A (ja) * 1997-07-18 1999-02-09 Zeria Pharmaceut Co Ltd ３−ベンゾイルインドール誘導体及びそれらを含有する医薬
AU3883099A (en) 1998-05-06 1999-11-23 Duke University Method of treating bladder and lower urinary tract syndromes
PL345166A1 (en) * 1998-06-30 2001-12-03 Zeria Pharm Co Ltd N-phenyl-n'-phenylpropylpiperazine derivatives and process for the preparation thereof
KR100368297B1 (ko) * 2000-05-31 2003-01-24 이승기 양성 전립선 비대증 치료용 메나퀴논 7
US7632955B2 (en) * 2001-12-13 2009-12-15 National Health Research Institutes Indole compounds
TWI317634B (en) * 2001-12-13 2009-12-01 Nat Health Research Institutes Aroyl indoles compounds
US7528165B2 (en) * 2001-12-13 2009-05-05 National Health Research Institutes Indole compounds
EP1833787A2 (en) * 2004-11-30 2007-09-19 Plexxikon, Inc. Indole derivatives for use as ppar active compounds
US7456289B2 (en) * 2004-12-31 2008-11-25 National Health Research Institutes Anti-tumor compounds
CA2621474A1 (en) * 2005-09-07 2007-03-15 Plexxikon, Inc. 1,3-disubstituted indole derivatives for use as ppar modulators
PE20090159A1 (es) * 2007-03-08 2009-02-21 Plexxikon Inc COMPUESTOS DERIVADOS DE ACIDO INDOL-PROPIONICO COMO MODULADORES PPARs
US9771316B2 (en) 2013-01-21 2017-09-26 Osaka University Phenoxyalkylamine compound

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935240A (en) 1987-06-04 1990-06-19 Ono Pharmaceutical Co., Ltd. Benzoylaminophenoxybutanoic acid derivatives
FR2632641B1 (fr) 1988-06-13 1990-10-12 Irceba ((aryl-4-piperazinyl-1)-2 ethoxy)-3 p-cymene, les derives ortho, meta, para monosubstitues ou disubstitues sur le noyau phenyle dudit produit, le procede de preparation desdits derives, et les medicaments contenant lesdits composes comme principe actif
FR2637596B1 (fr) 1988-10-11 1992-09-04 Irceba Methyl-4 ((aryl-4 piperazinyl-1)-2 ethyl)-5 thiazole et ses derives, leur procede de preparation et les medicaments en contenant
FR2658514B1 (fr) * 1990-02-19 1992-06-19 Irceba Nouveaux derives du methyl-4 thiazole, leurs procedes de preparation et les compositions pharmaceutiques en contenant.
GB9011335D0 (en) 1990-05-21 1990-07-11 Fujisawa Pharmaceutical Co Indolebutyric acid derivatives and process for preparation thereof
GB9115951D0 (en) * 1991-07-24 1991-09-11 Pfizer Ltd Indoles
CA2118697A1 (en) * 1991-09-11 1993-03-18 Satoshi Okada Indole derivatives as 5-alpha-reductase inhibitor
HRP930210A2 (en) * 1992-02-25 1995-06-30 Recordati Chem Pharm Heterobicyclic compounds and pharmaceutical preparations containing them
GB9204024D0 (en) * 1992-02-25 1992-04-08 Fujisawa Pharmaceutical Co Indole derivatives
EP0675109A1 (en) * 1992-12-21 1995-10-04 Taisho Pharmaceutical Co. Ltd N-substituted indole derivative

Also Published As

Publication number Publication date
ES2160158T3 (es) 2001-11-01
US5760040A (en) 1998-06-02
KR970702273A (ko) 1997-05-13
EP0753511B1 (en) 2001-07-11
ATE203012T1 (de) 2001-07-15
KR100349634B1 (ko) 2003-01-08
WO1995026955A1 (fr) 1995-10-12
AU2084195A (en) 1995-10-23
CN1067985C (zh) 2001-07-04
AU681021B2 (en) 1997-08-14
GR3036735T3 (en) 2001-12-31
EP0753511A1 (en) 1997-01-15
CN1145617A (zh) 1997-03-19
DE69521687T2 (de) 2001-10-25
PT753511E (pt) 2001-11-30
CA2186499A1 (en) 1995-10-12
UY25970A1 (es) 2001-08-27
DE69521687D1 (de) 2001-08-16
EP0753511A4 (en) 1997-07-23

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