DK0750618T3 - Oxazolidinonderivater og farmaceutiske præparater indeholdende dem - Google Patents

Oxazolidinonderivater og farmaceutiske præparater indeholdende dem

Info

Publication number
DK0750618T3
DK0750618T3 DK95913624T DK95913624T DK0750618T3 DK 0750618 T3 DK0750618 T3 DK 0750618T3 DK 95913624 T DK95913624 T DK 95913624T DK 95913624 T DK95913624 T DK 95913624T DK 0750618 T3 DK0750618 T3 DK 0750618T3
Authority
DK
Denmark
Prior art keywords
pharmaceutical preparations
oxazolidinone derivatives
preparations containing
present
derivatives
Prior art date
Application number
DK95913624T
Other languages
Danish (da)
English (en)
Inventor
Hiroyoshi Yamada
Kiyotaka Munesada
Mikio Taniguchi
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of DK0750618T3 publication Critical patent/DK0750618T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36—One oxygen atom
    • C07D263/38—One oxygen atom attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK95913624T 1994-03-15 1995-03-14 Oxazolidinonderivater og farmaceutiske præparater indeholdende dem DK0750618T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP4394994 1994-03-15
JP14656594 1994-06-28
JP6235167A JPH0873455A (ja) 1994-03-15 1994-09-29 オキサゾリジノン誘導体及びこれを有効成分とする医薬組成物
PCT/US1995/002972 WO1995025106A1 (en) 1994-03-15 1995-03-14 Oxazolidinone derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
DK0750618T3 true DK0750618T3 (da) 2003-06-10

Family

ID=27291734

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95913624T DK0750618T3 (da) 1994-03-15 1995-03-14 Oxazolidinonderivater og farmaceutiske præparater indeholdende dem

Country Status (14)

Country Link
EP (1) EP0750618B1 (de)
JP (2) JPH0873455A (de)
KR (1) KR100340365B1 (de)
CN (1) CN1143961A (de)
AT (1) ATE232862T1 (de)
AU (1) AU681953B2 (de)
CA (1) CA2183972C (de)
DE (1) DE69529670T2 (de)
DK (1) DK0750618T3 (de)
ES (1) ES2191048T3 (de)
LV (1) LV13155B (de)
NZ (1) NZ283011A (de)
PT (1) PT750618E (de)
WO (1) WO1995025106A1 (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2218088A1 (en) * 1995-05-11 1996-11-14 Pharmacia & Upjohn Company Spirocyclic and bicyclic diazinyl and carbazinyl oxazolidinones
JPH11512429A (ja) * 1995-09-15 1999-10-26 ファルマシア・アンド・アップジョン・カンパニー アミノアリールオキサゾリジノン ｎ−オキシド
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
ES2166073T3 (es) * 1996-04-11 2002-04-01 Upjohn Co Procedimiento para preparar oxazolidinonas.
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
DE19709443C1 (de) * 1997-03-07 1998-10-08 Clariant Gmbh Verfahren zur Herstellung von N-Carboxyalkyl-3-fluor-4-dialkylaminoanilinen und N-Carboxymethyl-3-fluor-4-morpholinoanilin und N-Carboxyisobutyl-3-fluor-4-morpholinoanilin
DE19750968A1 (de) * 1997-03-07 1998-09-10 Clariant Gmbh Verfahren zur Herstellung von N-Carboxyalkyl-3-fluor-4-dialkylaminoanilinen
US6037354A (en) * 1997-06-18 2000-03-14 Merck & Co., Inc. Alpha 1a adrenergic receptor antagonists
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
KR100467309B1 (ko) * 1997-09-04 2005-07-18 씨제이 주식회사 옥사졸리디논유도체및그의제조방법및항균제조성물
KR100463111B1 (ko) * 1997-10-30 2005-06-13 씨제이 주식회사 신규한옥사졸리디논유도체및제조방법및그를함유하는항균제조성물
AU739055B2 (en) * 1997-11-12 2001-10-04 Pharmacia & Upjohn Company Oxazolidinone derivatives and pharmaceutical compositions
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
ATE222894T1 (de) * 1998-02-13 2002-09-15 Upjohn Co Substituierte aminophenylisoxazolinderivate verwendbar als antimikrobielle agenzien
WO2003008389A1 (en) * 2001-07-16 2003-01-30 Ranbaxy Laboratories Limited Oxazolidinone derivatives as potential antimicrobials
CA2415965A1 (en) 2000-07-17 2002-01-24 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
WO2002064574A2 (en) 2001-02-07 2002-08-22 Ortho-Mcneil Pharmaceutical, Inc. Pyridoarylphenyl oxazolidinone antibacterials, and related compositions and methods
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US6956040B2 (en) 2001-07-16 2005-10-18 Ranbaxy Laboratories Limited Oxazolidinone piperazinyl derivatives as potential antimicrobials
KR100445437B1 (ko) * 2002-02-08 2004-08-21 한국과학기술연구원 네오마이신-옥사졸리디논 헤테로 이합체, 그의 제조방법및 그의 용도
AR038536A1 (es) 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7141588B2 (en) 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
CA2492743A1 (en) * 2002-07-11 2004-01-22 Wockhardt Limited Antimicrobial oxazolidinones, process of their preparation, and pharmaceutical compositions containing them
CA2492194A1 (en) * 2002-07-11 2004-01-22 Wockhardt Limited Antibacterial cyano-(substituted)-methylenepiperidinophenyl oxazolidinones targeting multiple ribonucleoproteins sites
WO2004009549A2 (en) * 2002-07-18 2004-01-29 Actelion Pharmaceuticals Ltd Piperidines useful for the treatment of central nervous system disorders
CA2491287A1 (en) 2002-08-12 2004-02-19 Pharmacia & Upjohn Company N-aryl-2-oxazolidinones and their derivatives
BR0316483A (pt) 2002-11-21 2005-10-11 Upjohn Co Derivados de n-(4-(piperazin-1-il)-fenil-2-oxazolidinona-5-carboxami da e compostos relacionados como agentes antibacterianos
EP1660488A1 (de) * 2003-08-25 2006-05-31 Warner-Lambert Company LLC Neue antibakterielle aryloxazolidinone
US7687627B2 (en) * 2003-09-08 2010-03-30 Wockhardt Limited Substituted piperidino phenyloxazolidinones having antimicrobial activity with improved in vivo efficacy
CN100545150C (zh) * 2003-09-12 2009-09-30 中国科学院上海药物研究所 含吡啶环的噁唑烷酮类化合物、制备方法及用途
US7304050B2 (en) 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
US20090018123A1 (en) * 2005-06-20 2009-01-15 Milind D Sindkhedkar Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation
ES2556183T3 (es) * 2006-05-09 2016-01-13 Wockhardt Limited Piperidinofeniloxazolidinonas sustituidas
US8288416B2 (en) 2006-09-25 2012-10-16 Wockhardt Ltd. Substituted piperidinophenyl oxazolidinones
BRPI1014213A2 (pt) 2009-03-27 2015-08-25 Council Scient Ind Res "1,4-dioxa-8-azaspiro [4,5] decanos substituídos úteis como fungicidas e processo para a preparação dos mesmos.
KR20130102614A (ko) 2010-11-03 2013-09-17 욱크하르트 리미티드 인산 모노-(1-[4-[(s)-5-(아세틸아미노메틸)-2-옥소-옥사졸리딘-3-일]-2,6-디플루오로페닐]-4-메톡시메틸피페리딘-4-일) 에스테르의 제조 방법
JP5796134B2 (ja) * 2011-09-29 2015-10-21 山東軒竹医薬科技有限公司 ビアリールヘテロ環で置換されたオキサゾリドン抗菌薬
CN104364240B (zh) * 2012-06-08 2017-02-22 四川贝力克生物技术有限责任公司 一种用于预防或治疗分支杆菌疾病的药物
WO2015173664A1 (en) 2014-05-14 2015-11-19 Wockhardt Limited Process for the preparation of (5s)-n-{3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide
US20210267953A1 (en) * 2018-07-25 2021-09-02 Cadila Healthcare Limited Substituted oxazolidinones for the treatment of mammalian infections
CA3183397A1 (en) 2020-06-18 2021-12-23 Daryl C. Drummond Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
JP3176626B2 (ja) * 1991-11-01 2001-06-18 ファルマシア・アンド・アップジョン・カンパニー 抗菌剤として有用な置換アリール−およびヘテロアリールフェニルオキサゾリジノン類
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny

Also Published As

Publication number Publication date
JPH0873455A (ja) 1996-03-19
CN1143961A (zh) 1997-02-26
KR100340365B1 (ko) 2002-11-23
MX9604072A (es) 1997-09-30
CA2183972A1 (en) 1995-09-21
PT750618E (pt) 2003-06-30
AU2099995A (en) 1995-10-03
DE69529670T2 (de) 2003-09-18
AU681953B2 (en) 1997-09-11
JPH09512785A (ja) 1997-12-22
DE69529670D1 (de) 2003-03-27
JP3628329B2 (ja) 2005-03-09
WO1995025106A1 (en) 1995-09-21
NZ283011A (en) 1997-09-22
LV13155B (en) 2004-06-20
ATE232862T1 (de) 2003-03-15
CA2183972C (en) 2005-07-05
ES2191048T3 (es) 2003-09-01
EP0750618B1 (de) 2003-02-19
EP0750618A1 (de) 1997-01-02

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