DK0648202T3 - Substituerede (arylalkylaminobenzyl)aminopropanamidderivater, fremstilling deraf og anvendelse som anti-epileptiske, neurobeskyttende og antidepressive midler - Google Patents

Substituerede (arylalkylaminobenzyl)aminopropanamidderivater, fremstilling deraf og anvendelse som anti-epileptiske, neurobeskyttende og antidepressive midler

Info

Publication number
DK0648202T3
DK0648202T3 DK94911181.9T DK94911181T DK0648202T3 DK 0648202 T3 DK0648202 T3 DK 0648202T3 DK 94911181 T DK94911181 T DK 94911181T DK 0648202 T3 DK0648202 T3 DK 0648202T3
Authority
DK
Denmark
Prior art keywords
hydrogen
neuroprotective
arylalkylaminobenzyl
epileptic
substituted
Prior art date
Application number
DK94911181.9T
Other languages
English (en)
Inventor
Philippe Dostert
Alberto Bonsignori
Paolo Pevarello
Mario Varasi
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Application granted granted Critical
Publication of DK0648202T3 publication Critical patent/DK0648202T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK94911181.9T 1993-04-01 1994-03-15 Substituerede (arylalkylaminobenzyl)aminopropanamidderivater, fremstilling deraf og anvendelse som anti-epileptiske, neurobeskyttende og antidepressive midler DK0648202T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939306899A GB9306899D0 (en) 1993-04-01 1993-04-01 Substituted (arylalkylaminobenzyl) aminopropionamide derivatives and process for their preparation

Publications (1)

Publication Number Publication Date
DK0648202T3 true DK0648202T3 (da) 1997-10-27

Family

ID=10733226

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94911181.9T DK0648202T3 (da) 1993-04-01 1994-03-15 Substituerede (arylalkylaminobenzyl)aminopropanamidderivater, fremstilling deraf og anvendelse som anti-epileptiske, neurobeskyttende og antidepressive midler

Country Status (21)

Country Link
US (1) US5449692A (da)
EP (1) EP0648202B1 (da)
JP (1) JP3542600B2 (da)
KR (1) KR950701905A (da)
CN (1) CN1035939C (da)
AT (1) ATE152442T1 (da)
AU (1) AU667169B2 (da)
CA (1) CA2136008C (da)
DE (1) DE69402935T2 (da)
DK (1) DK0648202T3 (da)
ES (1) ES2104370T3 (da)
FI (1) FI945582A0 (da)
GB (1) GB9306899D0 (da)
GR (1) GR3024150T3 (da)
HU (1) HUT70944A (da)
IL (1) IL108970A0 (da)
NZ (1) NZ263183A (da)
PL (1) PL306538A1 (da)
RU (1) RU94046144A (da)
WO (1) WO1994022809A1 (da)
ZA (1) ZA941964B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9515412D0 (en) * 1995-07-27 1995-09-27 Pharmacia Spa 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives
IT1283489B1 (it) * 1996-07-23 1998-04-21 Chiesi Farma Spa Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico
WO1999026614A1 (en) 1997-11-21 1999-06-03 Euro-Celtique S.A. Substituted 2-aminoacetamides and the use thereof
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
US6281211B1 (en) 1999-02-04 2001-08-28 Euro-Celtique S.A. Substituted semicarbazides and the use thereof
EP1169060B1 (en) * 1999-04-09 2005-08-31 Euro-Celtique S.A. Sodium channel blocker compositions and the use thereof
JP4350508B2 (ja) 2001-09-03 2009-10-21 ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー ガバペンチンまたはその類似体とα−アミノアミドとを含む薬剤組成物およびその鎮痛用途
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
BRPI0515154A (pt) * 2004-09-10 2008-07-08 Newron Pharm Spa uso de (halobenzilóxi)benzilamino-propanamidas para a fabricação de medicamentos ativos, compostos e composição farmacêutica
CA2626747A1 (en) * 2005-10-26 2007-05-03 Boehringer Ingelheim International Gmbh (hetero)aryl compounds with mch antagonistic activity and medicaments comprising these compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1140748A (en) * 1966-06-23 1969-01-22 Ici Ltd New carboxylic acid derivatives
US4049663A (en) * 1972-06-06 1977-09-20 Allen & Hanburys Limited Ethylene diamine derivatives
DE3010599A1 (de) * 1979-03-22 1980-10-09 Continental Pharma Derivate von glycinamid, deren herstellung und verwendung
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
US4728668A (en) * 1985-04-16 1988-03-01 Usv Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4631287A (en) * 1985-04-16 1986-12-23 Usv Pharmaceutical Corp. Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4839369A (en) * 1985-04-16 1989-06-13 Rorer Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4725619A (en) * 1985-04-16 1988-02-16 Usv Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
IL94466A (en) * 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation

Also Published As

Publication number Publication date
WO1994022809A1 (en) 1994-10-13
ATE152442T1 (de) 1997-05-15
ES2104370T3 (es) 1997-10-01
DE69402935T2 (de) 1997-11-20
IL108970A0 (en) 1994-06-24
GB9306899D0 (en) 1993-05-26
CN1104018A (zh) 1995-06-21
ZA941964B (en) 1994-10-19
GR3024150T3 (en) 1997-10-31
JPH08504828A (ja) 1996-05-28
EP0648202A1 (en) 1995-04-19
JP3542600B2 (ja) 2004-07-14
EP0648202B1 (en) 1997-05-02
RU94046144A (ru) 1996-09-27
FI945582A (fi) 1994-11-28
KR950701905A (ko) 1995-05-17
HU9403809D0 (en) 1995-02-28
AU6377694A (en) 1994-10-24
PL306538A1 (en) 1995-04-03
AU667169B2 (en) 1996-03-07
CN1035939C (zh) 1997-09-24
HUT70944A (en) 1995-11-28
CA2136008C (en) 2005-06-14
CA2136008A1 (en) 1994-10-13
DE69402935D1 (de) 1997-06-05
FI945582A0 (fi) 1994-11-28
US5449692A (en) 1995-09-12
NZ263183A (en) 1996-02-27

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