DK0647654T3 - Anomere fluor-ribosylaminer - Google Patents

Anomere fluor-ribosylaminer

Info

Publication number: DK0647654T3
Authority: DK; Denmark
Prior art keywords: anomeric; ribosylamines; fluoro; difluororibosyl; deoxynucleosides
Prior art date: 1993-09-16

Application number

DK94306670T

Other languages

Danish (da)

English (en)

Inventor

Charles David Jones

Thomas Edward Mabry

Larry Wayne Hertel

Julian Stanley Kroin

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-09-16

Filing date

1994-09-12

Publication date

2000-03-13

1994-09-12 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2000-03-13 Application granted granted Critical

2000-03-13 Publication of DK0647654T3 publication Critical patent/DK0647654T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Quinoline Compounds (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Catalysts (AREA)
Noodles (AREA)

DK94306670T 1993-09-16 1994-09-12 Anomere fluor-ribosylaminer DK0647654T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/122,876 US5480992A (en)	1993-09-16	1993-09-16	Anomeric fluororibosyl amines

Publications (1)

Publication Number	Publication Date
DK0647654T3 true DK0647654T3 (da)	2000-03-13

Family

ID=22405359

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94306670T DK0647654T3 (da)	1993-09-16	1994-09-12	Anomere fluor-ribosylaminer

Country Status (15)

Country	Link
US (3)	US5480992A (ja)
EP (1)	EP0647654B1 (ja)
JP (1)	JP3762445B2 (ja)
KR (1)	KR100322355B1 (ja)
AT (1)	ATE186731T1 (ja)
BR (1)	BR9403572A (ja)
CA (1)	CA2130124C (ja)
DE (1)	DE69421665T2 (ja)
DK (1)	DK0647654T3 (ja)
ES (1)	ES2139714T3 (ja)
FI (1)	FI113179B (ja)
GR (1)	GR3032603T3 (ja)
HU (1)	HU220672B1 (ja)
IL (2)	IL110932A (ja)
TW (1)	TW342392B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6906495B2 (en) *	2002-05-13	2005-06-14	Splashpower Limited	Contact-less power transfer
US7214791B2 (en) *	2004-07-01	2007-05-08	Shenzhen Hande Technology Co., Ltd.	Method for preparation of 2′-deoxy-2′, 2′-difluoro-β-cytidine or pharmaceutically acceptable salts thereof by using 1,6-anhydro-β-d-glucose as raw material
US20070191598A1 (en) *	2006-02-07	2007-08-16	Chemagis Ltd.	Process for Preparing Gemcitabine and Associated Intermediates
US20070249823A1 (en) *	2006-04-20	2007-10-25	Chemagis Ltd.	Process for preparing gemcitabine and associated intermediates
US20080262215A1 (en) *	2007-04-23	2008-10-23	Chemagis Ltd.	Gemcitabine production process

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2270235B1 (ja) *	1974-02-15	1982-09-03	Sanofi Sa
FR2315500A2 (fr) *	1975-06-24	1977-01-21	Labaz	Procede de preparation d'un diazidocyclohexanediol
US4526988A (en) *	1983-03-10	1985-07-02	Eli Lilly And Company	Difluoro antivirals and intermediate therefor
US4879377A (en) *	1983-11-18	1989-11-07	Bristol-Myers Company	Nucleoside process
CA1264738A (en) *	1984-12-04	1990-01-23	Eli Lilly And Company	Treatment of tumors in mammals
US4965374A (en) *	1987-08-28	1990-10-23	Eli Lilly And Company	Process for and intermediates of 2',2'-difluoronucleosides
JPH0232093A (ja) *	1988-06-08	1990-02-01	Merrell Dow Pharmaceut Inc	抗レトロウィルスジフルオロ化ヌクレオシド類

1993
- 1993-09-16 US US08/122,876 patent/US5480992A/en not_active Expired - Lifetime
1994
- 1994-08-11 TW TW083107347A patent/TW342392B/zh not_active IP Right Cessation
- 1994-08-15 CA CA002130124A patent/CA2130124C/en not_active Expired - Fee Related
- 1994-09-12 EP EP94306670A patent/EP0647654B1/en not_active Expired - Lifetime
- 1994-09-12 DE DE69421665T patent/DE69421665T2/de not_active Expired - Lifetime
- 1994-09-12 DK DK94306670T patent/DK0647654T3/da active
- 1994-09-12 ES ES94306670T patent/ES2139714T3/es not_active Expired - Lifetime
- 1994-09-12 AT AT94306670T patent/ATE186731T1/de active
- 1994-09-12 IL IL11093294A patent/IL110932A/xx not_active IP Right Cessation
- 1994-09-14 JP JP21985394A patent/JP3762445B2/ja not_active Expired - Fee Related
- 1994-09-15 KR KR1019940023346A patent/KR100322355B1/ko not_active IP Right Cessation
- 1994-09-15 HU HU9402646A patent/HU220672B1/hu not_active IP Right Cessation
- 1994-09-15 BR BR9403572A patent/BR9403572A/pt not_active Application Discontinuation
- 1994-09-15 FI FI944281A patent/FI113179B/fi not_active IP Right Cessation
1995
- 1995-05-30 US US08/453,736 patent/US5541345A/en not_active Expired - Lifetime
- 1995-05-30 US US08/453,734 patent/US5594155A/en not_active Expired - Lifetime
2000
- 2000-02-09 GR GR20000400301T patent/GR3032603T3/el unknown
- 2000-07-10 IL IL13724800A patent/IL137248A0/xx unknown

Also Published As

Publication number	Publication date
EP0647654A3 (ja)	1995-05-03
DE69421665T2 (de)	2000-05-25
EP0647654B1 (en)	1999-11-17
KR100322355B1 (ko)	2002-11-30
JPH07149783A (ja)	1995-06-13
CA2130124A1 (en)	1995-03-17
IL110932A0 (en)	1994-11-28
US5541345A (en)	1996-07-30
TW342392B (en)	1998-10-11
FI113179B (fi)	2004-03-15
ES2139714T3 (es)	2000-02-16
HU9402646D0 (en)	1994-12-28
IL137248A0 (en)	2001-07-24
JP3762445B2 (ja)	2006-04-05
ATE186731T1 (de)	1999-12-15
IL110932A (en)	2003-05-29
KR950008529A (ko)	1995-04-19
DE69421665D1 (de)	1999-12-23
CA2130124C (en)	2004-08-10
US5480992A (en)	1996-01-02
FI944281A0 (fi)	1994-09-15
US5594155A (en)	1997-01-14
EP0647654A2 (en)	1995-04-12
FI944281A (fi)	1995-03-17
BR9403572A (pt)	1995-05-16
HUT72590A (en)	1996-05-28
GR3032603T3 (en)	2000-05-31
HU220672B1 (hu)	2002-04-29

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