GR3032603T3 - Anomeric flouroribosyl amines. - Google Patents

Anomeric flouroribosyl amines.

Info

Publication number
GR3032603T3
GR3032603T3 GR20000400301T GR20000400301T GR3032603T3 GR 3032603 T3 GR3032603 T3 GR 3032603T3 GR 20000400301 T GR20000400301 T GR 20000400301T GR 20000400301 T GR20000400301 T GR 20000400301T GR 3032603 T3 GR3032603 T3 GR 3032603T3
Authority
GR
Greece
Prior art keywords
anomeric
flouroribosyl
amines
difluororibosyl
deoxynucleosides
Prior art date
Application number
GR20000400301T
Other languages
English (en)
Inventor
Larry Wayne Hertel
Charles David Jones
Julian Stanley Kroin
Thomas Edward Mabry
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of GR3032603T3 publication Critical patent/GR3032603T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
  • Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Noodles (AREA)
GR20000400301T 1993-09-16 2000-02-09 Anomeric flouroribosyl amines. GR3032603T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/122,876 US5480992A (en) 1993-09-16 1993-09-16 Anomeric fluororibosyl amines

Publications (1)

Publication Number Publication Date
GR3032603T3 true GR3032603T3 (en) 2000-05-31

Family

ID=22405359

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000400301T GR3032603T3 (en) 1993-09-16 2000-02-09 Anomeric flouroribosyl amines.

Country Status (15)

Country Link
US (3) US5480992A (el)
EP (1) EP0647654B1 (el)
JP (1) JP3762445B2 (el)
KR (1) KR100322355B1 (el)
AT (1) ATE186731T1 (el)
BR (1) BR9403572A (el)
CA (1) CA2130124C (el)
DE (1) DE69421665T2 (el)
DK (1) DK0647654T3 (el)
ES (1) ES2139714T3 (el)
FI (1) FI113179B (el)
GR (1) GR3032603T3 (el)
HU (1) HU220672B1 (el)
IL (2) IL110932A (el)
TW (1) TW342392B (el)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6906495B2 (en) * 2002-05-13 2005-06-14 Splashpower Limited Contact-less power transfer
US7214791B2 (en) * 2004-07-01 2007-05-08 Shenzhen Hande Technology Co., Ltd. Method for preparation of 2′-deoxy-2′, 2′-difluoro-β-cytidine or pharmaceutically acceptable salts thereof by using 1,6-anhydro-β-d-glucose as raw material
WO2007092705A2 (en) * 2006-02-07 2007-08-16 Chemagis Ltd. Process for preparing gemcitabine and associated intermediates
US20070249823A1 (en) * 2006-04-20 2007-10-25 Chemagis Ltd. Process for preparing gemcitabine and associated intermediates
US20080262215A1 (en) * 2007-04-23 2008-10-23 Chemagis Ltd. Gemcitabine production process

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2270235B1 (el) * 1974-02-15 1982-09-03 Sanofi Sa
FR2315500A2 (fr) * 1975-06-24 1977-01-21 Labaz Procede de preparation d'un diazidocyclohexanediol
US4526988A (en) * 1983-03-10 1985-07-02 Eli Lilly And Company Difluoro antivirals and intermediate therefor
US4879377A (en) * 1983-11-18 1989-11-07 Bristol-Myers Company Nucleoside process
DE3587500T2 (de) * 1984-12-04 1993-12-16 Lilly Co Eli Tumorbehandlung bei Säugetieren.
US4965374A (en) * 1987-08-28 1990-10-23 Eli Lilly And Company Process for and intermediates of 2',2'-difluoronucleosides
JPH0232093A (ja) * 1988-06-08 1990-02-01 Merrell Dow Pharmaceut Inc 抗レトロウィルスジフルオロ化ヌクレオシド類

Also Published As

Publication number Publication date
FI944281A (fi) 1995-03-17
ATE186731T1 (de) 1999-12-15
US5541345A (en) 1996-07-30
US5480992A (en) 1996-01-02
TW342392B (en) 1998-10-11
FI944281A0 (fi) 1994-09-15
EP0647654A2 (en) 1995-04-12
DE69421665T2 (de) 2000-05-25
EP0647654A3 (el) 1995-05-03
IL110932A (en) 2003-05-29
JP3762445B2 (ja) 2006-04-05
KR100322355B1 (ko) 2002-11-30
CA2130124A1 (en) 1995-03-17
KR950008529A (ko) 1995-04-19
IL137248A0 (en) 2001-07-24
FI113179B (fi) 2004-03-15
HU220672B1 (hu) 2002-04-29
US5594155A (en) 1997-01-14
HUT72590A (en) 1996-05-28
ES2139714T3 (es) 2000-02-16
IL110932A0 (en) 1994-11-28
DE69421665D1 (de) 1999-12-23
DK0647654T3 (da) 2000-03-13
BR9403572A (pt) 1995-05-16
HU9402646D0 (en) 1994-12-28
JPH07149783A (ja) 1995-06-13
CA2130124C (en) 2004-08-10
EP0647654B1 (en) 1999-11-17

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