DK0625989T3 - DNA-sekvenser kodende for hidtil ukendte vækst-/differentieringsfaktorer - Google Patents

DNA-sekvenser kodende for hidtil ukendte vækst-/differentieringsfaktorer

Info

Publication number
DK0625989T3
DK0625989T3 DK93903966T DK93903966T DK0625989T3 DK 0625989 T3 DK0625989 T3 DK 0625989T3 DK 93903966 T DK93903966 T DK 93903966T DK 93903966 T DK93903966 T DK 93903966T DK 0625989 T3 DK0625989 T3 DK 0625989T3
Authority
DK
Denmark
Prior art keywords
dna sequences
proteins
sequences encoding
differentiation factors
encoding novel
Prior art date
Application number
DK93903966T
Other languages
English (en)
Inventor
Helge Neidhardt
Gertrud Hoetten
Original Assignee
Bioph Biotech Entw Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioph Biotech Entw Pharm Gmbh filed Critical Bioph Biotech Entw Pharm Gmbh
Application granted granted Critical
Publication of DK0625989T3 publication Critical patent/DK0625989T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK93903966T 1992-02-12 1993-02-12 DNA-sekvenser kodende for hidtil ukendte vækst-/differentieringsfaktorer DK0625989T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92102324 1992-02-12
PCT/EP1993/000350 WO1993016099A2 (en) 1992-02-12 1993-02-12 Dna sequences encoding novel growth/differentiation factors

Publications (1)

Publication Number Publication Date
DK0625989T3 true DK0625989T3 (da) 2000-06-26

Family

ID=8209321

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93903966T DK0625989T3 (da) 1992-02-12 1993-02-12 DNA-sekvenser kodende for hidtil ukendte vækst-/differentieringsfaktorer

Country Status (16)

Country Link
EP (1) EP0625989B1 (da)
JP (2) JP3193050B2 (da)
KR (1) KR0172186B1 (da)
AT (1) ATE188996T1 (da)
CA (1) CA2129820C (da)
CZ (2) CZ287715B6 (da)
DE (1) DE69327645T2 (da)
DK (1) DK0625989T3 (da)
ES (1) ES2141761T3 (da)
GR (1) GR3032482T3 (da)
HU (1) HU218845B (da)
NZ (1) NZ249113A (da)
PT (1) PT625989E (da)
RU (1) RU2208638C2 (da)
UA (1) UA48105C2 (da)
WO (1) WO1993016099A2 (da)

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US7025959B1 (en) 1992-02-12 2006-04-11 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh MP121, a growth/differentiation factor of the TGF-β family
US7067637B1 (en) 1992-02-12 2006-06-27 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh Antibody or antibody fragments specific for a protein of the TGF-β family
DE19525416A1 (de) 1995-07-12 1997-01-16 Bioph Biotech Entw Pharm Gmbh Verwendung von MP52 zur Behandlung und Prävention von Erkrankungen des Nervensystems
US6120760A (en) 1992-02-12 2000-09-19 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Growth/differentiation factors of the TGF-β family
US5807713A (en) * 1992-02-12 1998-09-15 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung DNA encoding growth/differentiation factor
US6171584B1 (en) 1992-02-12 2001-01-09 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh Method of treatment with growth/differentiation factors of the TGF-β family
CA2153654A1 (en) 1993-01-12 1994-07-21 Se-Jin Lee Growth differentiation factor-5
CA2165776A1 (en) * 1993-07-09 1995-01-19 Se-Jin Lee Growth differentiation factor-6
JPH09503904A (ja) 1993-07-09 1997-04-22 ザ ジョーンズ ホプキンス ユニバーシティー スクール オブ メディシン 増殖分化因子−７
IL110589A0 (en) * 1993-08-10 1994-11-11 Bioph Biotech Entw Pharm Gmbh Growth/differentiation factor of the TGF- beta family
US6764994B1 (en) 1993-08-10 2004-07-20 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh Growth/differential factor of the TGF-B family
WO1995016035A2 (en) * 1993-12-07 1995-06-15 Genetics Institute, Inc. Bmp-12, bmp-13 and tendon-inducing compositions thereof
US6027919A (en) * 1993-12-07 2000-02-22 Genetics Institute, Inc. BMP-12 and BMP-13 proteins and DNA encoding them
IL114397A0 (en) * 1994-07-01 1995-10-31 Bioph Biotech Entw Pharm Gmbh Growth/differentiation factor of the TGF-beta-family
DE69518760T2 (de) * 1994-07-13 2001-05-23 The Johns Hopkins University School Of Medicine, Baltimore Wachstumsdifferenzierungsfaktor-12
WO1996014335A1 (en) 1994-11-07 1996-05-17 The Government Of The United States Of America, Asrepresented By The Secretary, Department Of Health And Human Services Cartilage-derived morphogenetic proteins
US5846770A (en) * 1994-11-22 1998-12-08 Genetics Institute, Inc. DNA molecules encoding human chordin
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US5700774A (en) * 1996-03-26 1997-12-23 Genetics Institute, Inc. Compositions comprising bone morphogenic proteins and truncated parathyroid hormone related peptide, and methods of inducing cartilage by administration of same
JPH1080273A (ja) * 1996-05-13 1998-03-31 Hoechst Yakuhin Kogyo Kk Ｍｐ５２に対するモノクローナル抗体
US5965403A (en) * 1996-09-18 1999-10-12 Genetics Institute, Inc. Nucleic acids encoding bone morphogenic protein-16 (BMP-16)
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US20010016646A1 (en) 1998-03-20 2001-08-23 David C. Rueger Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects
US7041641B2 (en) 1997-03-20 2006-05-09 Stryker Corporation Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
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US7344716B2 (en) 2003-05-13 2008-03-18 Depuy Spine, Inc. Transdiscal administration of specific inhibitors of pro-inflammatory cytokines
US8273347B2 (en) 2003-05-13 2012-09-25 Depuy Spine, Inc. Autologous treatment of degenerated disc with cells
US7553827B2 (en) 2003-08-13 2009-06-30 Depuy Spine, Inc. Transdiscal administration of cycline compounds
US7429378B2 (en) 2003-05-13 2008-09-30 Depuy Spine, Inc. Transdiscal administration of high affinity anti-MMP inhibitors
US8361467B2 (en) 2003-07-30 2013-01-29 Depuy Spine, Inc. Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints
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US8895540B2 (en) 2003-11-26 2014-11-25 DePuy Synthes Products, LLC Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
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US7575751B2 (en) 2004-04-27 2009-08-18 Research Development Foundation Activin-A mutants
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US20060069008A1 (en) 2004-09-28 2006-03-30 Sanjay Mistry Treatment of neurological deficits in the striatum or substanta nigra pars compacta
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US8147860B2 (en) 2005-12-06 2012-04-03 Etex Corporation Porous calcium phosphate bone material
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US20090298761A1 (en) 2006-05-17 2009-12-03 Donald Engelman Methods of treating cartilage defects using a soluble morphogenic protein complex
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
JP5484047B2 (ja) 2006-06-30 2014-05-07 バイオミメティック セラピューティクス， エルエルシー 回旋筋腱板傷害を処置するためのｐｄｇｆ−生体マトリックス組成物および方法
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Also Published As

Publication number Publication date
HU218845B (hu) 2000-12-28
AU666170B2 (en) 1996-02-01
AU3497193A (en) 1993-09-03
NZ249113A (en) 1996-07-26
WO1993016099A2 (en) 1993-08-19
CZ287810B6 (cs) 2001-02-14
DE69327645D1 (de) 2000-02-24
HU9402143D0 (en) 1994-09-28
JP3193050B2 (ja) 2001-07-30
GR3032482T3 (en) 2000-05-31
ES2141761T3 (es) 2000-04-01
RU94046367A (ru) 1997-03-27
EP0625989B1 (en) 2000-01-19
ATE188996T1 (de) 2000-02-15
EP0625989A1 (en) 1994-11-30
JPH09182593A (ja) 1997-07-15
JPH07503847A (ja) 1995-04-27
CA2129820C (en) 2003-06-17
CZ194294A3 (en) 1995-10-18
RU2208638C2 (ru) 2003-07-20
CA2129820A1 (en) 1993-08-19
JP3493105B2 (ja) 2004-02-03
UA48105C2 (uk) 2002-08-15
DE69327645T2 (de) 2000-09-07
KR950700331A (ko) 1995-01-16
HUT67683A (en) 1995-04-28
PT625989E (pt) 2000-06-30
WO1993016099A3 (en) 1993-09-30
CZ287715B6 (en) 2001-01-17
KR0172186B1 (ko) 1999-02-01

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