DK0450566T3 - Substituerede azoler, fremgangsmåde til deres fremstilling, midler indeholdende disse og deres anvendelse - Google Patents

Substituerede azoler, fremgangsmåde til deres fremstilling, midler indeholdende disse og deres anvendelse

Info

Publication number
DK0450566T3
DK0450566T3 DK91105178.7T DK91105178T DK0450566T3 DK 0450566 T3 DK0450566 T3 DK 0450566T3 DK 91105178 T DK91105178 T DK 91105178T DK 0450566 T3 DK0450566 T3 DK 0450566T3
Authority
DK
Denmark
Prior art keywords
preparation
processes
agents containing
substituted azoles
azoles
Prior art date
Application number
DK91105178.7T
Other languages
English (en)
Inventor
Adalbert Dr Wagner
Rainer Dr Henning
Hermann Dr Gerhards
Bernward Dr Schoelkens
Vevert Jean-Paul
Caille Jean-Claude
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Application granted granted Critical
Publication of DK0450566T3 publication Critical patent/DK0450566T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Coloring (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Detergent Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DK91105178.7T 1990-04-04 1991-04-02 Substituerede azoler, fremgangsmåde til deres fremstilling, midler indeholdende disse og deres anvendelse DK0450566T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4010797A DE4010797A1 (de) 1990-04-04 1990-04-04 Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung

Publications (1)

Publication Number Publication Date
DK0450566T3 true DK0450566T3 (da) 1995-10-30

Family

ID=6403704

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91105178.7T DK0450566T3 (da) 1990-04-04 1991-04-02 Substituerede azoler, fremgangsmåde til deres fremstilling, midler indeholdende disse og deres anvendelse

Country Status (25)

Country Link
US (2) US5350751A (da)
EP (1) EP0450566B1 (da)
JP (1) JP3212036B2 (da)
KR (1) KR910018376A (da)
CN (2) CN1031940C (da)
AT (1) ATE124696T1 (da)
AU (2) AU644857B2 (da)
CA (1) CA2039622A1 (da)
CZ (1) CZ280248B6 (da)
DE (2) DE4010797A1 (da)
DK (1) DK0450566T3 (da)
ES (1) ES2076395T3 (da)
FI (1) FI911584A (da)
HU (2) HU213096B (da)
IE (1) IE67790B1 (da)
IL (1) IL97760A (da)
MA (1) MA22112A1 (da)
MX (1) MX25204A (da)
MY (1) MY109937A (da)
NO (1) NO177266C (da)
NZ (2) NZ260561A (da)
PT (1) PT97254B (da)
RU (2) RU2060255C1 (da)
SK (1) SK278797B6 (da)
ZA (1) ZA912458B (da)

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DE4010797A1 (de) * 1990-04-04 1991-10-10 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
DE4023215A1 (de) * 1990-07-21 1992-01-23 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, sie enthaltende mittel und deren verwendung
PH31175A (en) * 1990-10-31 1998-03-20 Squibb & Sons Inc Indole and benzimi-dazole-substituted imidazole and benzimidazole derivatives.
US5374615A (en) * 1990-10-31 1994-12-20 E. R. Squibb & Sons, Inc. Indole- and benzimidazole-substituted imidazole and benzimidazole derivatives
DE4036706A1 (de) * 1990-11-17 1992-05-21 Hoechst Ag Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie
TW197428B (da) 1991-01-04 1993-01-01 Hoechst Ag
CA2058198A1 (en) * 1991-01-04 1992-07-05 Adalbert Wagner Azole derivatives, process for their preparation, and their use
GB9108811D0 (en) * 1991-04-24 1991-06-12 Erba Carlo Spa N-imidazolyl derivatives of substituted indole
TW215434B (da) * 1992-03-07 1993-11-01 Hoechst Ag
US5364869A (en) * 1992-03-09 1994-11-15 Abbott Laboratories Heterocycle-substituted benzyaminopyridine angiotensin II receptor antagonists
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JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
WO2011038097A2 (en) * 2009-09-23 2011-03-31 Amira Pharmaceuticals, Inc. Indolizine inhibitors of 5-lipoxygenase
WO2011038086A2 (en) * 2009-09-23 2011-03-31 Amira Pharmaceuticals, Inc. Indolizine inhibitors of 5-lipoxygenase
CN110483499A (zh) 2009-11-05 2019-11-22 圣母大学 咪唑并[1,2-a]吡啶类化合物及其合成及使用方法
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
JP6606491B2 (ja) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法
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Also Published As

Publication number Publication date
ZA912458B (en) 1991-12-24
IL97760A0 (en) 1992-06-21
MY109937A (en) 1997-10-31
US5350751A (en) 1994-09-27
CN1031940C (zh) 1996-06-05
CZ280248B6 (cs) 1995-12-13
CN1055361A (zh) 1991-10-16
HUT60734A (en) 1992-10-28
NO911302D0 (no) 1991-04-03
IL97760A (en) 1997-06-10
ES2076395T3 (es) 1995-11-01
CN1105993A (zh) 1995-08-02
HU213096B (en) 1997-02-28
CN1036263C (zh) 1997-10-29
JP3212036B2 (ja) 2001-09-25
FI911584A (fi) 1991-10-05
SK278797B6 (sk) 1998-03-04
DE4010797A1 (de) 1991-10-10
MX25204A (es) 1993-08-01
AU7401391A (en) 1991-10-10
US5440046A (en) 1995-08-08
CS9100906A2 (en) 1991-11-12
RU95108590A (ru) 1997-03-20
AU5256093A (en) 1994-02-24
RU2060255C1 (ru) 1996-05-20
PT97254B (pt) 1998-07-31
AU658781B2 (en) 1995-04-27
PT97254A (pt) 1992-01-31
NO177266C (no) 1995-08-16
HU911091D0 (en) 1991-10-28
DE59105897D1 (de) 1995-08-10
MA22112A1 (fr) 1991-12-31
JPH04234876A (ja) 1992-08-24
EP0450566B1 (de) 1995-07-05
IE911098A1 (en) 1991-10-09
HU211464A9 (en) 1995-11-28
AU644857B2 (en) 1993-12-23
IE67790B1 (en) 1996-04-17
EP0450566A1 (de) 1991-10-09
CA2039622A1 (en) 1991-10-05
NZ237644A (en) 1994-12-22
ATE124696T1 (de) 1995-07-15
NO177266B (no) 1995-05-08
NO911302L (no) 1991-10-07
NZ260561A (en) 1995-01-27
KR910018376A (ko) 1991-11-30
RU2092482C1 (ru) 1997-10-10
FI911584A0 (fi) 1991-04-02

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