NO177266C - Analogifremgangsmåte for fremstilling av terapeutisk aktive substituerte azoler - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive substituerte azoler

Info

Publication number: NO177266C
Authority: NO; Norway
Prior art keywords: preparation; therapeutically active; analogous process; active substituted; substituted azoles
Prior art date: 1990-04-04

Application number

NO911302A

Other languages

English (en)

Other versions

NO911302D0 (no

NO911302L (no

NO177266B (no

Inventor

Adalbert Wagner

Rainer Henning

Hermann Gerhards

Bernward Scholkens

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-04-04

Filing date

1991-04-03

Publication date

1995-08-16

1991-04-03 Application filed by Hoechst Ag filed Critical Hoechst Ag

1991-04-03 Publication of NO911302D0 publication Critical patent/NO911302D0/no

1991-10-07 Publication of NO911302L publication Critical patent/NO911302L/no

1995-01-12 Priority to NO950118A priority Critical patent/NO179705C/no

1995-05-08 Publication of NO177266B publication Critical patent/NO177266B/no

1995-08-16 Publication of NO177266C publication Critical patent/NO177266C/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Coloring (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Detergent Compositions (AREA)
Pyrrole Compounds (AREA)
Cephalosporin Compounds (AREA)

NO911302A 1990-04-04 1991-04-03 Analogifremgangsmåte for fremstilling av terapeutisk aktive substituerte azoler NO177266C (no)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
NO950118A NO179705C (no)	1990-04-04	1995-01-12	Nye azolderivater

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4010797A DE4010797A1 (de)	1990-04-04	1990-04-04	Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung

Publications (4)

Publication Number	Publication Date
NO911302D0 NO911302D0 (no)	1991-04-03
NO911302L NO911302L (no)	1991-10-07
NO177266B NO177266B (no)	1995-05-08
NO177266C true NO177266C (no)	1995-08-16

Family

ID=6403704

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO911302A NO177266C (no)	1990-04-04	1991-04-03	Analogifremgangsmåte for fremstilling av terapeutisk aktive substituerte azoler

Country Status (25)

Country	Link
US (2)	US5350751A (no)
EP (1)	EP0450566B1 (no)
JP (1)	JP3212036B2 (no)
KR (1)	KR910018376A (no)
CN (2)	CN1031940C (no)
AT (1)	ATE124696T1 (no)
AU (2)	AU644857B2 (no)
CA (1)	CA2039622A1 (no)
CZ (1)	CZ280248B6 (no)
DE (2)	DE4010797A1 (no)
DK (1)	DK0450566T3 (no)
ES (1)	ES2076395T3 (no)
FI (1)	FI911584A (no)
HU (2)	HU213096B (no)
IE (1)	IE67790B1 (no)
IL (1)	IL97760A (no)
MA (1)	MA22112A1 (no)
MX (1)	MX25204A (no)
MY (1)	MY109937A (no)
NO (1)	NO177266C (no)
NZ (2)	NZ260561A (no)
PT (1)	PT97254B (no)
RU (2)	RU2060255C1 (no)
SK (1)	SK278797B6 (no)
ZA (1)	ZA912458B (no)

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DE4010797A1 (de) *	1990-04-04	1991-10-10	Hoechst Ag	Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
DE4023215A1 (de) *	1990-07-21	1992-01-23	Hoechst Ag	Substituierte azole, verfahren zu deren herstellung, sie enthaltende mittel und deren verwendung
PH31175A (en) *	1990-10-31	1998-03-20	Squibb & Sons Inc	Indole and benzimi-dazole-substituted imidazole and benzimidazole derivatives.
US5374615A (en) *	1990-10-31	1994-12-20	E. R. Squibb & Sons, Inc.	Indole- and benzimidazole-substituted imidazole and benzimidazole derivatives
DE4036706A1 (de) *	1990-11-17	1992-05-21	Hoechst Ag	Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie
TW197428B (no)	1991-01-04	1993-01-01	Hoechst Ag
CA2058198A1 (en) *	1991-01-04	1992-07-05	Adalbert Wagner	Azole derivatives, process for their preparation, and their use
GB9108811D0 (en) *	1991-04-24	1991-06-12	Erba Carlo Spa	N-imidazolyl derivatives of substituted indole
TW215434B (no) *	1992-03-07	1993-11-01	Hoechst Ag
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RU2103262C1 (ru) *	1992-07-16	1998-01-27	Лонца АГ Гампель/Валлис	Способ получения 2-замещенных 5-хлоримидазол-4-карбальдегидов
EP0614889A1 (de) *	1993-03-12	1994-09-14	Lonza Ag	Verfahren zur Herstellung von gegebenenfalls 2-substituierten 5-Chlorimidazol-4-carbaldehyden
US5442075A (en) *	1993-03-12	1995-08-15	Lonza Ltd.	Process for the production of 2-substituted 5-chlorimidazole-4-carbaldehydes
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HUE026011T2 (en)	2006-03-22	2016-05-30	Hoffmann La Roche	Pyrazoles as 11-beta-HSD-1
EP2170930B3 (en)	2007-06-04	2013-10-02	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
JP2011522828A (ja)	2008-06-04	2011-08-04	シナジーファーマシューティカルズインコーポレイテッド	胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
AU2009270833B2 (en)	2008-07-16	2015-02-19	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
WO2011038086A2 (en) *	2009-09-23	2011-03-31	Amira Pharmaceuticals, Inc.	Indolizine inhibitors of 5-lipoxygenase
US20120214840A1 (en) *	2009-09-23	2012-08-23	Panmira Pharmaceuticals, Llc	Indolizine inhibitors of 5-lipoxygenase
CN110483499A (zh)	2009-11-05	2019-11-22	圣母大学	咪唑并[1,2-a]吡啶类化合物及其合成及使用方法
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
WO2014151206A1 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
CA2905435A1 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
EP3004138B1 (en)	2013-06-05	2024-03-13	Bausch Health Ireland Limited	Ultra-pure agonists of guanylate cyclase c, method of making and using same
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US4859691A (en) *	1987-07-08	1989-08-22	Ciba-Geigy Corporation	Certain 1,2-benzisoxazole derivatives
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GB8724912D0 (en) *	1987-10-23	1987-11-25	Wellcome Found	Indole derivatives
US5015651A (en) *	1988-01-07	1991-05-14	E. I. Du Pont De Nemours And Company	Treatment of hypertension with 1,2,4-angiotensin II antagonists
CA1338238C (en) *	1988-01-07	1996-04-09	David John Carini	Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
JP2614756B2 (ja) *	1988-08-10	1997-05-28	日本ケミファ株式会社	イミダゾール誘導体およびその製造法ならびにこれを含有する抗潰瘍剤
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DE4010797A1 (de) *	1990-04-04	1991-10-10	Hoechst Ag	Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
DE4023215A1 (de) *	1990-07-21	1992-01-23	Hoechst Ag	Substituierte azole, verfahren zu deren herstellung, sie enthaltende mittel und deren verwendung
TW215434B (no) *	1992-03-07	1993-11-01	Hoechst Ag

1990
- 1990-04-04 DE DE4010797A patent/DE4010797A1/de not_active Withdrawn
1991
- 1991-03-28 NZ NZ260561A patent/NZ260561A/xx unknown
- 1991-03-28 NZ NZ237644A patent/NZ237644A/en unknown
- 1991-04-02 AT AT91105178T patent/ATE124696T1/de not_active IP Right Cessation
- 1991-04-02 CZ CS91906A patent/CZ280248B6/cs not_active IP Right Cessation
- 1991-04-02 SK SK906-91A patent/SK278797B6/sk unknown
- 1991-04-02 US US07/679,233 patent/US5350751A/en not_active Expired - Lifetime
- 1991-04-02 MY MYPI91000552A patent/MY109937A/en unknown
- 1991-04-02 DK DK91105178.7T patent/DK0450566T3/da active
- 1991-04-02 ES ES91105178T patent/ES2076395T3/es not_active Expired - Lifetime
- 1991-04-02 EP EP91105178A patent/EP0450566B1/de not_active Expired - Lifetime
- 1991-04-02 FI FI911584A patent/FI911584A/fi unknown
- 1991-04-02 DE DE59105897T patent/DE59105897D1/de not_active Expired - Lifetime
- 1991-04-03 MX MX2520491A patent/MX25204A/es unknown
- 1991-04-03 ZA ZA912458A patent/ZA912458B/xx unknown
- 1991-04-03 IL IL97760A patent/IL97760A/xx not_active IP Right Cessation
- 1991-04-03 CN CN91102043A patent/CN1031940C/zh not_active Expired - Fee Related
- 1991-04-03 IE IE109891A patent/IE67790B1/en not_active IP Right Cessation
- 1991-04-03 JP JP09611991A patent/JP3212036B2/ja not_active Expired - Lifetime
- 1991-04-03 CA CA002039622A patent/CA2039622A1/en not_active Abandoned
- 1991-04-03 AU AU74013/91A patent/AU644857B2/en not_active Ceased
- 1991-04-03 RU SU914894882A patent/RU2060255C1/ru active
- 1991-04-03 NO NO911302A patent/NO177266C/no unknown
- 1991-04-04 KR KR1019910005416A patent/KR910018376A/ko active IP Right Grant
- 1991-04-04 MA MA22381A patent/MA22112A1/fr unknown
- 1991-04-04 PT PT97254A patent/PT97254B/pt not_active IP Right Cessation
- 1991-04-04 HU HU911091A patent/HU213096B/hu not_active IP Right Cessation
1993
- 1993-12-21 AU AU52560/93A patent/AU658781B2/en not_active Ceased
1994
- 1994-05-27 US US08/250,491 patent/US5440046A/en not_active Expired - Lifetime
- 1994-10-22 CN CN94117640A patent/CN1036263C/zh not_active Expired - Fee Related
1995
- 1995-05-30 RU RU9595108590A patent/RU2092482C1/ru active
- 1995-06-28 HU HU95P/P00507P patent/HU211464A9/hu unknown

Also Published As

Publication number	Publication date
IL97760A0 (en)	1992-06-21
MA22112A1 (fr)	1991-12-31
HU911091D0 (en)	1991-10-28
HU213096B (en)	1997-02-28
US5440046A (en)	1995-08-08
NO911302D0 (no)	1991-04-03
ATE124696T1 (de)	1995-07-15
EP0450566A1 (de)	1991-10-09
AU5256093A (en)	1994-02-24
IL97760A (en)	1997-06-10
CZ280248B6 (cs)	1995-12-13
IE911098A1 (en)	1991-10-09
DE4010797A1 (de)	1991-10-10
ES2076395T3 (es)	1995-11-01
CN1036263C (zh)	1997-10-29
MX25204A (es)	1993-08-01
PT97254B (pt)	1998-07-31
ZA912458B (en)	1991-12-24
CN1031940C (zh)	1996-06-05
IE67790B1 (en)	1996-04-17
HUT60734A (en)	1992-10-28
CN1105993A (zh)	1995-08-02
RU2092482C1 (ru)	1997-10-10
HU211464A9 (en)	1995-11-28
RU95108590A (ru)	1997-03-20
FI911584A (fi)	1991-10-05
RU2060255C1 (ru)	1996-05-20
KR910018376A (ko)	1991-11-30
CN1055361A (zh)	1991-10-16
NZ237644A (en)	1994-12-22
NO911302L (no)	1991-10-07
EP0450566B1 (de)	1995-07-05
JP3212036B2 (ja)	2001-09-25
SK278797B6 (sk)	1998-03-04
DE59105897D1 (de)	1995-08-10
CS9100906A2 (en)	1991-11-12
CA2039622A1 (en)	1991-10-05
FI911584A0 (fi)	1991-04-02
NO177266B (no)	1995-05-08
MY109937A (en)	1997-10-31
US5350751A (en)	1994-09-27
AU7401391A (en)	1991-10-10
AU644857B2 (en)	1993-12-23
DK0450566T3 (da)	1995-10-30
PT97254A (pt)	1992-01-31
AU658781B2 (en)	1995-04-27
NZ260561A (en)	1995-01-27
JPH04234876A (ja)	1992-08-24

Publication	Publication Date	Title
NO177266C (no)	1995-08-16	Analogifremgangsmåte for fremstilling av terapeutisk aktive substituerte azoler
DE3365772D1 (en)	1986-10-09	1,4-dihydropyridines, process for their preparation and their application as pharmaceutical preparations
DK599785A (da)	1986-06-22	Blokpolyestere og detergentkompositioner indeholdende disse
FI823923L (fi)	1983-05-18	Antifibrinolytiskt aktiva foereningar
ES2062374T3 (es)	1994-12-16	Heteroarilpiperazinas, agentes antipsicoticos.
IL57577A0 (en)	1979-10-31	1,2-dihydroquinolin-2-one derivatives,process for their preparation and pharmaceutical compositions containing the same
FI933903A0 (fi)	1993-09-07	Substituerade cyklohexanderivat, foerfarande foer framstaellning daerav och anvaendning av foereningar foer behandling av sjukdomar
NO924598D0 (no)	1992-11-27	Fremstilling av substituerte piperidiner
ES8203356A1 (es)	1982-04-01	Procedimiento para la preparacion de nuevas n-ariloxazolidi-nonas-2
DK0393424T3 (da)	1996-02-05	Fremgangsmåde til fremstilling af 2,7-diazabicyclo(3.3.0)octaner
DE59106966D1 (de)	1996-01-11	Verfahren zur Herstellung von 3-Amino-2-(het)aroyl-acrylsäurederivaten.
DE3564684D1 (en)	1988-10-06	Tetrahydrothienopyridines, process for their preparation and their pharmaceutical application
DK0623620T3 (da)	1999-06-07	5-HT3-pyrrolopyrazinderivater
SE9203824D0 (sv)	1992-12-18	Benzofuranylimidazole derivatives a process for the preparation and therapeutical compositions containing the same
DK0552631T3 (da)	1998-05-11	Alfa-Aryl-alfa-hydroxy-beta-imidazolinyl-propionsyreamider
ES2054631T3 (es)	1994-08-16	1-(2-halogeno-alcoxi-bencenosulfonil)-3-heteroaril-ureas, 3-substituidas.
FI922518A (fi)	1993-11-30	Menetelmä farmaseuttisesti käyttökelpoisten pilokarpiinijohdannaisten valmistamiseksi